CCDC6 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description coiled-coil domain containing 6|This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.[provided by RefSeq, Sep 2010] (NCBI Entrez Gene Database, 8030)
External Link http://www.ncbi.nlm.nih.gov/gene/8030
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Genes

213 interacting proteins for CCDC6 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABLIM1 actin binding LIM protein 1
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AKAP1 A kinase (PRKA) anchor protein 1
AMPD2 adenosine monophosphate deaminase 2
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
BABAM1 BRISC and BRCA1 A complex member 1
BAD BCL2-associated agonist of cell death
BAIAP2 BAI1-associated protein 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BUB3 BUB3 mitotic checkpoint protein
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD2AP CD2-associated protein
CDC25C cell division cycle 25C
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK16 cyclin-dependent kinase 16
CDK17 cyclin-dependent kinase 17
CDK18 cyclin-dependent kinase 18
CDK2 cyclin-dependent kinase 2
CEP170 centrosomal protein 170kDa
CEP170B centrosomal protein 170B
CHEK1 checkpoint kinase 1
CLASP1 cytoplasmic linker associated protein 1
CLASP2 cytoplasmic linker associated protein 2
CREB1 cAMP responsive element binding protein 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRTC2 CREB regulated transcription coactivator 2
CRTC3 CREB regulated transcription coactivator 3
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CUL1 cullin 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYLD cylindromatosis (turban tumor syndrome)
DCAF4 DDB1 and CUL4 associated factor 4
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND1A DENN/MADD domain containing 1A
DENND4A DENN/MADD domain containing 4A
DENND4C DENN/MADD domain containing 4C
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DMTN dematin actin binding protein
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOCK11 dedicator of cytokinesis 11
DOCK7 dedicator of cytokinesis 7
EDC3 enhancer of mRNA decapping 3
EIF4B eukaryotic translation initiation factor 4B
EIF4E2 eukaryotic translation initiation factor 4E family member 2
ELAVL1 ELAV like RNA binding protein 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EXO1 exonuclease 1
FAM175B family with sequence similarity 175, member B
FAM83B family with sequence similarity 83, member B
FBXO38 F-box protein 38
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOXO3 forkhead box O3
GAPVD1 GTPase activating protein and VPS9 domains 1
GIGYF1 GRB10 interacting GYF protein 1
GIGYF2 GRB10 interacting GYF protein 2
GLYATL3 glycine-N-acyltransferase-like 3
GMPS guanine monphosphate synthase
GRIP1 glutamate receptor interacting protein 1
GTF2I general transcription factor IIi
HDAC1 histone deacetylase 1
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HLTF helicase-like transcription factor
HNRNPR heterogeneous nuclear ribonucleoprotein R
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IGBP1 immunoglobulin (CD79A) binding protein 1
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
KIAA0355 KIAA0355
KIAA0930 KIAA0930
KIAA1671 KIAA1671
KIF1B kinesin family member 1B
KIF1C kinesin family member 1C
KIF3A kinesin family member 3A
KLC2 kinesin light chain 2
KLC4 kinesin light chain 4
KSR1 kinase suppressor of ras 1
LARP1 La ribonucleoprotein domain family, member 1
LIMA1 LIM domain and actin binding 1
LMO7 LIM domain 7
LUZP1 leucine zipper protein 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK3 mitogen-activated protein kinase 3
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MAST2 microtubule associated serine/threonine kinase 2
MAX MYC associated factor X
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MCMBP minichromosome maintenance complex binding protein
MTMR12 myotubularin related protein 12
MYC v-myc avian myelocytomatosis viral oncogene homolog
NADK NAD kinase
NAV1 neuron navigator 1
NCKAP1 NCK-associated protein 1
NCKIPSD NCK interacting protein with SH3 domain
NELFA negative elongation factor complex member A
NELFB negative elongation factor complex member B
NF1 neurofibromin 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUP98 nucleoporin 98kDa
PAAF1 proteasomal ATPase-associated factor 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARP8 poly (ADP-ribose) polymerase family, member 8
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHLDB2 pleckstrin homology-like domain, family B, member 2
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PKM pyruvate kinase, muscle
PKP2 plakophilin 2
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHA7 pleckstrin homology domain containing, family A member 7
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PPP4C protein phosphatase 4, catalytic subunit
PPP4R1 protein phosphatase 4, regulatory subunit 1
PPP4R2 protein phosphatase 4, regulatory subunit 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PUM1 pumilio RNA-binding family member 1
R3HDM1 R3H domain containing 1
R3HDM2 R3H domain containing 2
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAE1 ribonucleic acid export 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASAL2 RAS protein activator like 2
REEP4 receptor accessory protein 4
RICTOR RPTOR independent companion of MTOR, complex 2
RTKN rhotekin
SAMD4A sterile alpha motif domain containing 4A
SAMD4B sterile alpha motif domain containing 4B
SCML2 sex comb on midleg-like 2 (Drosophila)
SF3A1 splicing factor 3a, subunit 1, 120kDa
SH3PXD2A SH3 and PX domains 2A
SH3RF1 SH3 domain containing ring finger 1
SH3RF3 SH3 domain containing ring finger 3
SHKBP1 SH3KBP1 binding protein 1
SHROOM3 shroom family member 3
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SKP1 S-phase kinase-associated protein 1
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SORBS1 sorbin and SH3 domain containing 1
SORBS2 sorbin and SH3 domain containing 2
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SRP68 signal recognition particle 68kDa
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STK3 serine/threonine kinase 3
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D22A TBC1 domain family, member 22A
TBC1D22B TBC1 domain family, member 22B
TBC1D4 TBC1 domain family, member 4
TBC1D5 TBC1 domain family, member 5
TCP1 t-complex 1
TP53BP2 tumor protein p53 binding protein 2
TPD52L1 tumor protein D52-like 1
TRIM28 tripartite motif containing 28
TRIM32 tripartite motif containing 32
TRIP12 thyroid hormone receptor interactor 12
TSC2 tuberous sclerosis 2
TTC28 tetratricopeptide repeat domain 28
UBC ubiquitin C
UHRF1BP1L UHRF1 binding protein 1-like
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP19 ubiquitin specific peptidase 19
USP54 ubiquitin specific peptidase 54
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
USP8 ubiquitin specific peptidase 8
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VPS33B vacuolar protein sorting 33 homolog B (yeast)
WNK1 WNK lysine deficient protein kinase 1
YLPM1 YLP motif containing 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZCCHC8 zinc finger, CCHC domain containing 8
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF207 zinc finger protein 207