CCDC88C Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description coiled-coil domain containing 88C|This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the dishevelled protein and is a negative regulator of the Wnt signalling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the dishevelled protein. Dishevelled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintenance, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain. [provided by RefSeq, Jan 2013] (NCBI Entrez Gene Database, 440193)
External Link http://www.ncbi.nlm.nih.gov/gene/440193
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Genes

413 interacting proteins for CCDC88C from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A1CF APOBEC1 complementation factor
ACLY ATP citrate lyase
AHNAK AHNAK nucleoprotein
AIM1 absent in melanoma 1
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ALKBH5 AlkB family member 5, RNA demethylase
ALMS1 Alstrom syndrome protein 1
ALYREF Aly/REF export factor
AMER1 APC membrane recruitment protein 1
AMOTL1 angiomotin like 1
AMOTL2 angiomotin like 2
ANAPC1 anaphase promoting complex subunit 1
ANAPC5 anaphase promoting complex subunit 5
ANXA2 annexin A2
APC adenomatous polyposis coli
API5 apoptosis inhibitor 5
APP amyloid beta (A4) precursor protein
ATAD3A ATPase family, AAA domain containing 3A
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
AUH AU RNA binding protein/enoyl-CoA hydratase
BAG2 BCL2-associated athanogene 2
BAG3 BCL2-associated athanogene 3
BAG5 BCL2-associated athanogene 5
BUD31 BUD31 homolog (S. cerevisiae)
C14ORF166 chromosome 14 open reading frame 166
C19ORF53 chromosome 19 open reading frame 53
C1QBP complement component 1, q subcomponent binding protein
CALD1 caldesmon 1
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CAPRIN1 cell cycle associated protein 1
CCDC77 coiled-coil domain containing 77
CDC42 cell division cycle 42
CELF1 CUGBP, Elav-like family member 1
CEP192 centrosomal protein 192kDa
CEP295 centrosomal protein 295kDa
CEP72 centrosomal protein 72kDa
CEP85 centrosomal protein 85kDa
CEP89 centrosomal protein 89kDa
CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1
CIRBP cold inducible RNA binding protein
CKAP4 cytoskeleton-associated protein 4
CKAP5 cytoskeleton associated protein 5
CNTROB centrobin, centrosomal BRCA2 interacting protein
COL17A1 collagen, type XVII, alpha 1
COLGALT1 collagen beta(1-O)galactosyltransferase 1
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CPT1A carnitine palmitoyltransferase 1A (liver)
CSDE1 cold shock domain containing E1, RNA-binding
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
DAP3 death associated protein 3
DARS aspartyl-tRNA synthetase
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DAZAP1 DAZ associated protein 1
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DUS3L dihydrouridine synthase 3-like (S. cerevisiae)
DVL1 dishevelled segment polarity protein 1
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EFTUD2 elongation factor Tu GTP binding domain containing 2
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF3D eukaryotic translation initiation factor 3, subunit D
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF3G eukaryotic translation initiation factor 3, subunit G
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF3K eukaryotic translation initiation factor 3, subunit K
EIF3L eukaryotic translation initiation factor 3, subunit L
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF4B eukaryotic translation initiation factor 4B
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF4H eukaryotic translation initiation factor 4H
ELAVL1 ELAV like RNA binding protein 1
EMG1 EMG1 N1-specific pseudouridine methyltransferase
EPRS glutamyl-prolyl-tRNA synthetase
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERH enhancer of rudimentary homolog (Drosophila)
EWSR1 EWS RNA-binding protein 1
EXOSC4 exosome component 4
EXOSC5 exosome component 5
EXOSC7 exosome component 7
EXOSC9 exosome component 9
FAM98B family with sequence similarity 98, member B
FASTKD2 FAST kinase domains 2
FBL fibrillarin
FGFBP1 fibroblast growth factor binding protein 1
FMR1 fragile X mental retardation 1
FUBP1 far upstream element (FUSE) binding protein 1
FUBP3 far upstream element (FUSE) binding protein 3
FUS FUS RNA binding protein
FXR1 fragile X mental retardation, autosomal homolog 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GEMIN5 gem (nuclear organelle) associated protein 5
GLTSCR2 glioma tumor suppressor candidate region gene 2
GTF2I general transcription factor IIi
GTPBP10 GTP-binding protein 10 (putative)
GVINP1 GTPase, very large interferon inducible pseudogene 1
H1FX H1 histone family, member X
HDLBP high density lipoprotein binding protein
HIST1H1B histone cluster 1, H1b
HIST1H1C histone cluster 1, H1c
HIST1H1E histone cluster 1, H1e
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPL heterogeneous nuclear ribonucleoprotein L
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSPA1B heat shock 70kDa protein 1B
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HTATSF1 HIV-1 Tat specific factor 1
IARS isoleucyl-tRNA synthetase
IFI16 interferon, gamma-inducible protein 16
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
INADL InaD-like (Drosophila)
INTS3 integrator complex subunit 3
IQGAP1 IQ motif containing GTPase activating protein 1
ITSN2 intersectin 2
KARS lysyl-tRNA synthetase
KCTD12 potassium channel tetramerization domain containing 12
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KHSRP KH-type splicing regulatory protein
KPNB1 karyopherin (importin) beta 1
LAD1 ladinin 1
LARP4 La ribonucleoprotein domain family, member 4
LARS leucyl-tRNA synthetase
LATS2 large tumor suppressor kinase 2
LDHA lactate dehydrogenase A
LDHB lactate dehydrogenase B
LIG3 ligase III, DNA, ATP-dependent
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC59 leucine rich repeat containing 59
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYZ lysozyme
LZTS2 leucine zipper, putative tumor suppressor 2
MAP4 microtubule-associated protein 4
MAPK8 mitogen-activated protein kinase 8
MARK2 MAP/microtubule affinity-regulating kinase 2
MARS methionyl-tRNA synthetase
MATR3 matrin 3
MCM3 minichromosome maintenance complex component 3
MCM5 minichromosome maintenance complex component 5
MED1 mediator complex subunit 1
MGME1 mitochondrial genome maintenance exonuclease 1
MIA3 melanoma inhibitory activity family, member 3
MOGS mannosyl-oligosaccharide glucosidase
MPDZ multiple PDZ domain protein
MPG N-methylpurine-DNA glycosylase
MPHOSPH9 M-phase phosphoprotein 9
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPS11 mitochondrial ribosomal protein S11
MRPS14 mitochondrial ribosomal protein S14
MRPS18B mitochondrial ribosomal protein S18B
MRPS18C mitochondrial ribosomal protein S18C
MRPS2 mitochondrial ribosomal protein S2
MRPS23 mitochondrial ribosomal protein S23
MRPS27 mitochondrial ribosomal protein S27
MRPS28 mitochondrial ribosomal protein S28
MRPS31 mitochondrial ribosomal protein S31
MRPS34 mitochondrial ribosomal protein S34
MRPS35 mitochondrial ribosomal protein S35
MRPS9 mitochondrial ribosomal protein S9
MSH2 mutS homolog 2
MTDH metadherin
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NCL nucleolin
NINL ninein-like
NOA1 nitric oxide associated 1
NONO non-POU domain containing, octamer-binding
NOP14 NOP14 nucleolar protein
NOTCH1 notch 1
NOTCH2 notch 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
NUP160 nucleoporin 160kDa
NUSAP1 nucleolar and spindle associated protein 1
NXF1 nuclear RNA export factor 1
OFD1 oral-facial-digital syndrome 1
PABPN1 poly(A) binding protein, nuclear 1
PARD3 par-3 family cell polarity regulator
PARP1 poly (ADP-ribose) polymerase 1
PCBP1 poly(rC) binding protein 1
PCBP2 poly(rC) binding protein 2
PCM1 pericentriolar material 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PEG10 paternally expressed 10
PHLDB2 pleckstrin homology-like domain, family B, member 2
PKM pyruvate kinase, muscle
PKP3 plakophilin 3
PKP4 plakophilin 4
PLEC plectin
PNO1 partner of NOB1 homolog (S. cerevisiae)
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POLRMT polymerase (RNA) mitochondrial (DNA directed)
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPF19 pre-mRNA processing factor 19
PRPF4 pre-mRNA processing factor 4
PRRC2C proline-rich coiled-coil 2C
PSPC1 paraspeckle component 1
PTBP1 polypyrimidine tract binding protein 1
PTCD3 pentatricopeptide repeat domain 3
PTRF polymerase I and transcript release factor
PUF60 poly-U binding splicing factor 60KDa
QARS glutaminyl-tRNA synthetase
RANBP2 RAN binding protein 2
RARS arginyl-tRNA synthetase
RARS2 arginyl-tRNA synthetase 2, mitochondrial
RASAL2 RAS protein activator like 2
RBM14 RNA binding motif protein 14
RBM15 RNA binding motif protein 15
RBM19 RNA binding motif protein 19
RBM27 RNA binding motif protein 27
RBM3 RNA binding motif (RNP1, RRM) protein 3
RBM39 RNA binding motif protein 39
RBMX RNA binding motif protein, X-linked
RECQL RecQ helicase-like
RFC1 replication factor C (activator 1) 1, 145kDa
RFC2 replication factor C (activator 1) 2, 40kDa
RNASEH1 ribonuclease H1
RNMT RNA (guanine-7-) methyltransferase
RPL17 ribosomal protein L17
RPL19 ribosomal protein L19
RPL22 ribosomal protein L22
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL26 ribosomal protein L26
RPL27A ribosomal protein L27a
RPL31 ribosomal protein L31
RPL32 ribosomal protein L32
RPL35 ribosomal protein L35
RPL36A ribosomal protein L36a
RPL38 ribosomal protein L38
RPL5 ribosomal protein L5
RPL7A ribosomal protein L7a
RPL8 ribosomal protein L8
RPP38 ribonuclease P/MRP 38kDa subunit
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS12 ribosomal protein S12
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15A ribosomal protein S15a
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS2 ribosomal protein S2
RPS23 ribosomal protein S23
RPS24 ribosomal protein S24
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS27 ribosomal protein S27
RPS28 ribosomal protein S28
RPS29 ribosomal protein S29
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS4X ribosomal protein S4, X-linked
RPS4Y2 ribosomal protein S4, Y-linked 2
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RSL1D1 ribosomal L1 domain containing 1
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase
S100A10 S100 calcium binding protein A10
SAFB2 scaffold attachment factor B2
SART1 squamous cell carcinoma antigen recognized by T cells
SDCCAG3 serologically defined colon cancer antigen 3
SEC16A SEC16 homolog A (S. cerevisiae)
SEPT2 septin 2
SEPT9 septin 9
SERBP1 SERPINE1 mRNA binding protein 1
SF3A1 splicing factor 3a, subunit 1, 120kDa
SF3A2 splicing factor 3a, subunit 2, 66kDa
SF3A3 splicing factor 3a, subunit 3, 60kDa
SF3B1 splicing factor 3b, subunit 1, 155kDa
SF3B2 splicing factor 3b, subunit 2, 145kDa
SF3B3 splicing factor 3b, subunit 3, 130kDa
SF3B5 splicing factor 3b, subunit 5, 10kDa
SFPQ splicing factor proline/glutamine-rich
SGPL1 sphingosine-1-phosphate lyase 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLIRP SRA stem-loop interacting RNA binding protein
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SND1 staphylococcal nuclease and tudor domain containing 1
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SNRPB2 small nuclear ribonucleoprotein polypeptide B
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SOX15 SRY (sex determining region Y)-box 15
SPATS2L spermatogenesis associated, serine-rich 2-like
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP9 signal recognition particle 9kDa
SRPRB signal recognition particle receptor, B subunit
SRSF11 serine/arginine-rich splicing factor 11
SRSF2 serine/arginine-rich splicing factor 2
SRSF3 serine/arginine-rich splicing factor 3
SRSF4 serine/arginine-rich splicing factor 4
SRSF5 serine/arginine-rich splicing factor 5
SRSF6 serine/arginine-rich splicing factor 6
STRAP serine/threonine kinase receptor associated protein
STXBP4 syntaxin binding protein 4
SUB1 SUB1 homolog (S. cerevisiae)
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TARDBP TAR DNA binding protein
TCHP trichoplein, keratin filament binding
TFAM transcription factor A, mitochondrial
TFB2M transcription factor B2, mitochondrial
THRAP3 thyroid hormone receptor associated protein 3
TNRC6B trinucleotide repeat containing 6B
TOX4 TOX high mobility group box family member 4
TP53 tumor protein p53
TRA2B transformer 2 beta homolog (Drosophila)
TRIM25 tripartite motif containing 25
TRIM27 tripartite motif containing 27
TRIM28 tripartite motif containing 28
TRIM29 tripartite motif containing 29
TRIM37 tripartite motif containing 37
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae)
TRMT6 tRNA methyltransferase 6
TRMT61A tRNA methyltransferase 61A
TUFM Tu translation elongation factor, mitochondrial
U2AF2 U2 small nuclear RNA auxiliary factor 2
U2SURP U2 snRNP-associated SURP domain containing
UBC ubiquitin C
USP10 ubiquitin specific peptidase 10
USP39 ubiquitin specific peptidase 39
USP54 ubiquitin specific peptidase 54
WBSCR22 Williams Beuren syndrome chromosome region 22
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
XRN2 5'-3' exoribonuclease 2
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZC2HC1A zinc finger, C2HC-type containing 1A
ZC3H15 zinc finger CCCH-type containing 15