| Dataset | Guide to Pharmacology Protein Ligands of Receptors |
| Category | physical interactions |
| Type | ligand (protein) |
| Description | chemokine (C-C motif) ligand 11|This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 6356) |
| External Link | http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=6356 |
| Similar Terms | |
| Downloads & Tools |
4 receptors of the CCL11 ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.
