CCL17 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description chemokine (C-C motif) ligand 17|This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 6361)
External Link http://www.ncbi.nlm.nih.gov/gene/6361
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Genes

3 interacting proteins for CCL17 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CCR4 chemokine (C-C motif) receptor 4
CCR8 chemokine (C-C motif) receptor 8
VCAM1 vascular cell adhesion molecule 1