| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | chemokine (C-C motif) ligand 21|This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 6366) |
| External Link | https://ncbi.nlm.nih.gov/gene/6366 |
| Similar Terms | |
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498 genes differentially expressed following the CCL21 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CA2 | carbonic anhydrase II | 0.013127 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0120444 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0118097 |
| XPO7 | exportin 7 | 0.011651 |
| ADD3 | adducin 3 (gamma) | 0.0115581 |
| S100A7 | S100 calcium binding protein A7 | 0.0110238 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0106586 |
| BEX1 | brain expressed, X-linked 1 | 0.0102236 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00994509 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00993958 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00962504 |
| TSPAN8 | tetraspanin 8 | 0.00942721 |
| REEP5 | receptor accessory protein 5 | 0.00941149 |
| TFDP1 | transcription factor Dp-1 | 0.00931248 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00923531 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00909542 |
| CCNG1 | cyclin G1 | 0.00907707 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00902845 |
| XIC | X chromosome inactivation center | 0.00885809 |
| EXOC5 | exocyst complex component 5 | 0.00880948 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00876068 |
| CD200 | CD200 molecule | 0.00860389 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 0.00856288 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00851808 |
| PRDX2 | peroxiredoxin 2 | 0.00845095 |
| MRPL19 | mitochondrial ribosomal protein L19 | 0.00836463 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00824408 |
| LYZ | lysozyme | 0.00816872 |
| DCTN4 | dynactin 4 (p62) | 0.00812879 |
| NEBL | nebulette | 0.00811922 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00811211 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00805685 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00800586 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00798164 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00793858 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00792703 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00787911 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00787547 |
| MECOM | MDS1 and EVI1 complex locus | 0.00785963 |
| GPC3 | glypican 3 | 0.0078328 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00778949 |
| MRPS33 | mitochondrial ribosomal protein S33 | 0.00773357 |
| ITGA6 | integrin, alpha 6 | 0.0076819 |
| YIPF5 | Yip1 domain family, member 5 | 0.00767262 |
| EGR2 | early growth response 2 | 0.00762856 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0076153 |
| COMMD10 | COMM domain containing 10 | 0.00761085 |
| FZD6 | frizzled class receptor 6 | 0.00760956 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00760867 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00757143 |
| FERMT1 | fermitin family member 1 | 0.00756694 |
| RBBP4 | retinoblastoma binding protein 4 | 0.0075362 |
| TMEM230 | transmembrane protein 230 | 0.00747878 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00746024 |
| SLC35A5 | solute carrier family 35, member A5 | 0.00742339 |
| ITM2C | integral membrane protein 2C | 0.00742094 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.00740038 |
| FOLR1 | folate receptor 1 (adult) | 0.00734442 |
| GCH1 | GTP cyclohydrolase 1 | 0.00733357 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00733093 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00732016 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.00729057 |
| HOPX | HOP homeobox | 0.00727886 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00725293 |
| MCL1 | myeloid cell leukemia 1 | 0.00722529 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00718883 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.00717151 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00712473 |
| NRN1 | neuritin 1 | 0.00711694 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0070986 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00709169 |
| PDHB | pyruvate dehydrogenase (lipoamide) beta | 0.00708034 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | 0.00706849 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00703836 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00702646 |
| RETREG1 | reticulophagy regulator 1 | 0.00701097 |
| HBB | hemoglobin, beta | 0.00700586 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00700486 |
| SET | SET nuclear proto-oncogene | 0.0069982 |
| BTG3 | BTG family, member 3 | 0.00696574 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | 0.006891 |
| KRT1 | keratin 1, type II | 0.00687966 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00687297 |
| FBN1 | fibrillin 1 | 0.00687124 |
| CFI | complement factor I | 0.00686347 |
| OPHN1 | oligophrenin 1 | 0.00685075 |
| FABP7 | fatty acid binding protein 7, brain | 0.00678117 |
| RGCC | regulator of cell cycle | 0.0067696 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00674767 |
| FOXG1 | forkhead box G1 | 0.00673584 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00672945 |
| SPRR1A | small proline-rich protein 1A | 0.00672229 |
| MRPS28 | mitochondrial ribosomal protein S28 | 0.00669767 |
| PLS3 | plastin 3 | 0.00669144 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00668653 |
| RCAN1 | regulator of calcineurin 1 | 0.00668176 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | 0.00667945 |
| NREP | neuronal regeneration related protein | 0.00667532 |
| DEFB1 | defensin, beta 1 | 0.00667245 |
| MFAP2 | microfibrillar-associated protein 2 | 0.00664944 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00664881 |
| GMFG | glia maturation factor, gamma | 0.00662477 |
| TMEM204 | transmembrane protein 204 | 0.00662383 |
| LAGE3 | L antigen family, member 3 | 0.00661599 |
| CLIC5 | chloride intracellular channel 5 | 0.00661544 |
| CLDND1 | claudin domain containing 1 | 0.0066095 |
| GRP | gastrin-releasing peptide | 0.00660563 |
| MRPS18B | mitochondrial ribosomal protein S18B | 0.0065899 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.00655704 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00655211 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00651513 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00651102 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.00650573 |
| PRRX1 | paired related homeobox 1 | 0.00650196 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 0.00648723 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00647864 |
| DOK5 | docking protein 5 | 0.0064659 |
| RHOA | ras homolog family member A | 0.00646362 |
| ESD | esterase D | 0.00645633 |
| ATP10B | ATPase, class V, type 10B | 0.00644526 |
| TTC1 | tetratricopeptide repeat domain 1 | 0.00643692 |
| KRT81 | keratin 81, type II | 0.00642127 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0064107 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.0064071 |
| NDN | necdin, melanoma antigen (MAGE) family member | 0.00640336 |
| WDR61 | WD repeat domain 61 | 0.00638982 |
| KIAA0100 | KIAA0100 | 0.00638682 |
| CALML3 | calmodulin-like 3 | 0.0063749 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00636434 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0063604 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00635431 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00633678 |
| NSG1 | neuron specific gene family member 1 | 0.00632943 |
| NEK7 | NIMA-related kinase 7 | 0.00632527 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00630371 |
| STON1 | stonin 1 | 0.00629855 |
| STOM | stomatin | 0.00628893 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00628892 |
| MEG3 | maternally expressed 3 (non-protein coding) | 0.00628798 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00628386 |
| MRPL17 | mitochondrial ribosomal protein L17 | 0.00626014 |
| EGR3 | early growth response 3 | 0.00625563 |
| PXDN | peroxidasin | 0.00625324 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00624465 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00623363 |
| S100P | S100 calcium binding protein P | 0.00622687 |
| ACOT7 | acyl-CoA thioesterase 7 | 0.00622079 |
| MCTS1 | malignant T cell amplified sequence 1 | 0.00621688 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00619935 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00618795 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00617371 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00617344 |
| PLP1 | proteolipid protein 1 | 0.00617302 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00616514 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00615254 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.00614552 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.00614501 |
| GAB2 | GRB2-associated binding protein 2 | 0.00612469 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 0.00610331 |
| ATP5F1C | ATP synthase F1 subunit gamma | 0.00609988 |
| OLFML3 | olfactomedin-like 3 | 0.00609812 |
| ATP5PD | ATP synthase peripheral stalk subunit d | 0.00608745 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.00606641 |
| CNN2 | calponin 2 | 0.0060631 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.00604831 |
| MAGED2 | melanoma antigen family D2 | 0.00604362 |
| CDC42 | cell division cycle 42 | 0.00604318 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00604024 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00602685 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.00602331 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00600701 |
| CST7 | cystatin F (leukocystatin) | 0.00599832 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00599754 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | 0.0059714 |
| DENND1B | DENN/MADD domain containing 1B | 0.0059695 |
| MX2 | MX dynamin-like GTPase 2 | 0.00595795 |
| C1QBP | complement component 1, q subcomponent binding protein | 0.00595781 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00593124 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00593 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 0.00592021 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00589413 |
| MED6 | mediator complex subunit 6 | 0.00589143 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.00585355 |
| KLF6 | Kruppel-like factor 6 | 0.00584858 |
| CANX | calnexin | 0.00584811 |
| TRAM1 | translocation associated membrane protein 1 | 0.00584723 |
| BMP2 | bone morphogenetic protein 2 | 0.00584172 |
| MFAP4 | microfibrillar-associated protein 4 | 0.0058381 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00583661 |
| ICAM3 | intercellular adhesion molecule 3 | 0.00583073 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00581694 |
| PRKCQ | protein kinase C, theta | 0.00580805 |
| HSBP1 | heat shock factor binding protein 1 | 0.00579134 |
| S100B | S100 calcium binding protein B | 0.00577701 |
| RHOH | ras homolog family member H | 0.00577451 |
| MRPL23 | mitochondrial ribosomal protein L23 | 0.00576454 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00576358 |
| YIPF6 | Yip1 domain family, member 6 | 0.00575242 |
| ZNF207 | zinc finger protein 207 | 0.00574298 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | 0.00574032 |
| MOCS2 | molybdenum cofactor synthesis 2 | 0.00572736 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00571923 |
| TOX | thymocyte selection-associated high mobility group box | 0.00570403 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00570207 |
| LRRC17 | leucine rich repeat containing 17 | 0.00569074 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00568507 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00568341 |
| CRYZ | crystallin, zeta (quinone reductase) | 0.00568336 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00566328 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00564877 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 0.00564039 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 0.00561866 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 0.00560901 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00560512 |
| POPDC3 | popeye domain containing 3 | 0.00560286 |
| EDN3 | endothelin 3 | 0.00559839 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00559503 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00559299 |
| IVL | involucrin | 0.00557466 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | 0.00557365 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | 0.00557316 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00557055 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | 0.00556545 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.0055565 |
| AK2 | adenylate kinase 2 | 0.00555536 |
| HIKESHI | heat shock protein nuclear import factor hikeshi | 0.005549 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.00554718 |
| SPRR1B | small proline-rich protein 1B | 0.00554114 |
| SELENOT | selenoprotein T | 0.00554006 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.00553036 |
| SLC22A18 | solute carrier family 22, member 18 | 0.00552245 |
| LTA4H | leukotriene A4 hydrolase | 0.00552102 |
| KRCC1 | lysine-rich coiled-coil 1 | 0.00551064 |
| CD93 | CD93 molecule | 0.00550879 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00550843 |
| TSPAN3 | tetraspanin 3 | 0.00550111 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00549371 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00549036 |
| RAB4A | RAB4A, member RAS oncogene family | 0.00548143 |
| CTTN | cortactin | 0.00547925 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00547378 |
| TNNC1 | troponin C type 1 (slow) | 0.00546486 |
| TCTN3 | tectonic family member 3 | 0.00545836 |
| TMEM45A | transmembrane protein 45A | 0.00545613 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | 0.00545555 |
| EMP2 | epithelial membrane protein 2 | 0.00543441 |
| PLPBP | pyridoxal phosphate binding protein | 0.00543309 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.00543196 |
| KRT20 | keratin 20, type I | 0.00542421 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00541121 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0157467 |
| APOD | apolipoprotein D | -0.0144514 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0142467 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0140518 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0137006 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0125433 |
| MMP7 | matrix metallopeptidase 7 | -0.01126 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0110165 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.0109632 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.010878 |
| GSDME | gasdermin E | -0.010685 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0103073 |
| CD9 | CD9 molecule | -0.0102804 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0101177 |
| NOTCH2 | notch 2 | -0.0099259 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.0097836 |
| PROM1 | prominin 1 | -0.00976006 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00967021 |
| PTK2B | protein tyrosine kinase 2 beta | -0.0095652 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00952158 |
| MAP7 | microtubule-associated protein 7 | -0.0094998 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00937817 |
| STK26 | serine/threonine protein kinase 26 | -0.00932662 |
| HDAC9 | histone deacetylase 9 | -0.00929504 |
| PDLIM4 | PDZ and LIM domain 4 | -0.00928562 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00923278 |
| TGM2 | transglutaminase 2 | -0.00923144 |
| TSPAN12 | tetraspanin 12 | -0.00908262 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00901435 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00899612 |
| LTF | lactotransferrin | -0.0088988 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00865321 |
| AGR2 | anterior gradient 2 | -0.00850765 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | -0.00850428 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00850015 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00842678 |
| PMP22 | peripheral myelin protein 22 | -0.00827607 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00822673 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.00815233 |
| CENPU | centromere protein U | -0.00811432 |
| KRT19 | keratin 19, type I | -0.0080793 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00800781 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00795534 |
| NRCAM | neuronal cell adhesion molecule | -0.00793485 |
| WDR7 | WD repeat domain 7 | -0.00792389 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00781704 |
| PCP4 | Purkinje cell protein 4 | -0.00774649 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00764368 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | -0.00764125 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00762978 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00761102 |
| LCN2 | lipocalin 2 | -0.00760439 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00758286 |
| PXDC1 | PX domain containing 1 | -0.00757971 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00752845 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | -0.00752181 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00744112 |
| KCTD5 | potassium channel tetramerization domain containing 5 | -0.00738174 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | -0.00738105 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -0.0073776 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.00735018 |
| CAPN1 | calpain 1, (mu/I) large subunit | -0.00731728 |
| NOTCH2NL | notch 2 N-terminal like | -0.00731621 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00727876 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00726368 |
| NPY | neuropeptide Y | -0.00721126 |
| DIPK1A | divergent protein kinase domain 1A | -0.00718972 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00717332 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | -0.00717045 |
| RRAGD | Ras-related GTP binding D | -0.00714354 |
| DGKZ | diacylglycerol kinase, zeta | -0.00711518 |
| KRT7 | keratin 7, type II | -0.00706877 |
| H1-2 | H1.2 linker histone, cluster member | -0.00706638 |
| IPO13 | importin 13 | -0.00706087 |
| NKX3-1 | NK3 homeobox 1 | -0.00702085 |
| PAEP | progestagen-associated endometrial protein | -0.00700955 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.00698174 |
| CDC20 | cell division cycle 20 | -0.00697675 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00697482 |
| RTN3 | reticulon 3 | -0.00697255 |
| EMP3 | epithelial membrane protein 3 | -0.00691106 |
| SUGP2 | SURP and G patch domain containing 2 | -0.00688965 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00685317 |
| EFHD2 | EF-hand domain family, member D2 | -0.00678553 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00677157 |
| MLPH | melanophilin | -0.00672824 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.00672434 |
| GLRX2 | glutaredoxin 2 | -0.00670558 |
| KLHL24 | kelch-like family member 24 | -0.00669655 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.00666677 |
| PLXNB2 | plexin B2 | -0.00664789 |
| RAPSN | receptor-associated protein of the synapse | -0.00664286 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00660931 |
| ANKRD36 | ankyrin repeat domain 36 | -0.00660258 |
| XYLT1 | xylosyltransferase I | -0.00658685 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00658673 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | -0.00657415 |
| TOX3 | TOX high mobility group box family member 3 | -0.00653136 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00652852 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00652763 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma | -0.00651941 |
| MUC1 | mucin 1, cell surface associated | -0.00651858 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.00649926 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00645838 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00645434 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00644463 |
| GUSB | glucuronidase, beta | -0.00642384 |
| DOCK4 | dedicator of cytokinesis 4 | -0.00642226 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0064196 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00640398 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00638567 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.00637284 |
| ITGA8 | integrin, alpha 8 | -0.00636742 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.006342 |
| CD84 | CD84 molecule | -0.00632575 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.00632485 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | -0.00630205 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.00627928 |
| YBX3 | Y box binding protein 3 | -0.00627017 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.00625604 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.00625109 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | -0.0062278 |
| BLNK | B-cell linker | -0.00622662 |
| TXNIP | thioredoxin interacting protein | -0.00622334 |
| HIP1R | huntingtin interacting protein 1 related | -0.00621491 |
| SIKE1 | suppressor of IKBKE 1 | -0.00619533 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) | -0.00619497 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00619083 |
| NXN | nucleoredoxin | -0.00616084 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.00615196 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00613669 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | -0.00612053 |
| ZNF91 | zinc finger protein 91 | -0.00611457 |
| KLK3 | kallikrein-related peptidase 3 | -0.0060981 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00608709 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | -0.00608141 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00606785 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00603231 |
| MACROD1 | MACRO domain containing 1 | -0.00602761 |
| TPD52L1 | tumor protein D52-like 1 | -0.00600981 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00600652 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | -0.00599356 |
| TNC | tenascin C | -0.00598525 |
| PNKP | polynucleotide kinase 3'-phosphatase | -0.00596625 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00596502 |
| CEP70 | centrosomal protein 70kDa | -0.00594693 |
| CDK17 | cyclin-dependent kinase 17 | -0.00593316 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00591706 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.00591448 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0059067 |
| ARL8B | ADP-ribosylation factor-like 8B | -0.00589197 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00587455 |
| NAPA | N-ethylmaleimide-sensitive factor attachment protein, alpha | -0.00587271 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00587071 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00586949 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00585225 |
| RAB8A | RAB8A, member RAS oncogene family | -0.00584226 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | -0.00583515 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00581666 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00581017 |
| CLGN | calmegin | -0.00579776 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | -0.00579769 |
| C3 | complement component 3 | -0.00579679 |
| IRS2 | insulin receptor substrate 2 | -0.00579349 |
| FADS1 | fatty acid desaturase 1 | -0.00577912 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00577391 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -0.00577378 |
| TLN1 | talin 1 | -0.00576303 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.00575195 |
| COBL | cordon-bleu WH2 repeat protein | -0.00574989 |
| HMGB2 | high mobility group box 2 | -0.00573939 |
| PLD3 | phospholipase D family, member 3 | -0.00573498 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | -0.00572669 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00571293 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | -0.0057071 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.00570425 |
| DPP4 | dipeptidyl-peptidase 4 | -0.00569459 |
| MYO10 | myosin X | -0.00569134 |
| CLCN7 | chloride channel, voltage-sensitive 7 | -0.00568917 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00568879 |
| CAMTA2 | calmodulin binding transcription activator 2 | -0.00568757 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00568545 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00566809 |
| CUL9 | cullin 9 | -0.00565924 |
| MAOA | monoamine oxidase A | -0.00564285 |
| RANGAP1 | Ran GTPase activating protein 1 | -0.00564268 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.00563831 |
| KLK2 | kallikrein-related peptidase 2 | -0.00563622 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00563198 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00562866 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00562386 |
| TGFB1 | transforming growth factor, beta 1 | -0.00562014 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00560976 |
| FAIM | Fas apoptotic inhibitory molecule | -0.0056063 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00559625 |
| LIPG | lipase, endothelial | -0.00558984 |
| DENND4B | DENN/MADD domain containing 4B | -0.00558838 |
| TSPO | translocator protein (18kDa) | -0.00558636 |
| GHR | growth hormone receptor | -0.00558273 |
| CCN3 | cellular communication network factor 3 | -0.00558272 |
| PYGL | phosphorylase, glycogen, liver | -0.00557976 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -0.00556231 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.00555874 |
| DNMBP | dynamin binding protein | -0.00555162 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.0055489 |
| FADS3 | fatty acid desaturase 3 | -0.00554739 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.00554553 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | -0.00552744 |
| TAPBP | TAP binding protein (tapasin) | -0.00550571 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00548389 |
| H1-0 | H1.0 linker histone | -0.00547792 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 | -0.0054773 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00547476 |
| WTAP | Wilms tumor 1 associated protein | -0.00545424 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 | -0.00545385 |
| KIAA0930 | KIAA0930 | -0.00545186 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00544479 |
| ZNF12 | zinc finger protein 12 | -0.00544234 |
| STK38 | serine/threonine kinase 38 | -0.00543251 |
| HOXC10 | homeobox C10 | -0.00543001 |
| ATG4B | autophagy related 4B, cysteine peptidase | -0.00542848 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00542657 |
| ANAPC2 | anaphase promoting complex subunit 2 | -0.0054264 |
| PEX6 | peroxisomal biogenesis factor 6 | -0.00541888 |
| PASK | PAS domain containing serine/threonine kinase | -0.00539669 |
| DES | desmin | -0.00539258 |
| COMT | catechol-O-methyltransferase | -0.00534412 |
| NOTCH1 | notch 1 | -0.00534151 |
| PLXNB1 | plexin B1 | -0.00533225 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00532755 |
| ZNF83 | zinc finger protein 83 | -0.005326 |
| SOAT1 | sterol O-acyltransferase 1 | -0.00529727 |
| TRIM37 | tripartite motif containing 37 | -0.00529597 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | -0.00529141 |
| C7ORF26 | chromosome 7 open reading frame 26 | -0.00528722 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00528472 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa | -0.00528356 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.00528351 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | -0.00527988 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.00527461 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | -0.00526827 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00526517 |
| MRPS2 | mitochondrial ribosomal protein S2 | -0.0052635 |
| APMAP | adipocyte plasma membrane associated protein | -0.00526088 |
| CRYM | crystallin, mu | -0.00526074 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 | -0.0052425 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00523647 |
| PGAP3 | post-GPI attachment to proteins 3 | -0.00522355 |
