CCL27 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description chemokine (C-C motif) ligand 27|This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 10850)
External Link http://www.ncbi.nlm.nih.gov/gene/10850
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Genes

2 interacting proteins for CCL27 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CCR10 chemokine (C-C motif) receptor 10
GRK6 G protein-coupled receptor kinase 6