CCL4 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description chemokine (C-C motif) ligand 4|The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012] (NCBI Entrez Gene Database, 6351)
External Link https://ncbi.nlm.nih.gov/gene/6351
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Genes

498 genes differentially expressed following the CCL4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0144158
HSPA1A heat shock 70kDa protein 1A 0.0141794
PEG10 paternally expressed 10 0.0122344
KYNU kynureninase 0.0116268
FTH1 ferritin, heavy polypeptide 1 0.0114085
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0109423
KRT14 keratin 14, type I 0.0108449
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.0107482
COG7 component of oligomeric golgi complex 7 0.010681
TM4SF1 transmembrane 4 L six family member 1 0.0104162
MMP7 matrix metallopeptidase 7 0.010329
CXCL10 chemokine (C-X-C motif) ligand 10 0.0100939
KRT7 keratin 7, type II 0.0100716
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0100489
FN1 fibronectin 1 0.00996674
FGG fibrinogen gamma chain 0.00975324
HMOX1 heme oxygenase 1 0.00963793
ZNF91 zinc finger protein 91 0.00955429
MEIS2 Meis homeobox 2 0.00950507
IPO13 importin 13 0.00941589
GSDME gasdermin E 0.00940035
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.00935683
CCL20 chemokine (C-C motif) ligand 20 0.00925266
MAGEA3 melanoma antigen family A3 0.00924889
LPAR6 lysophosphatidic acid receptor 6 0.00923986
TFPI2 tissue factor pathway inhibitor 2 0.00915426
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00904285
NVL nuclear VCP-like 0.00900011
IL32 interleukin 32 0.00889351
BCHE butyrylcholinesterase 0.00883986
MVP major vault protein 0.00876698
GARS1 glycyl-tRNA synthetase 1 0.00871496
HSPB1 heat shock 27kDa protein 1 0.00868214
AMIGO2 adhesion molecule with Ig-like domain 2 0.00861177
SQSTM1 sequestosome 1 0.00860308
VNN1 vanin 1 0.00848785
C10ORF10 chromosome 10 open reading frame 10 0.00838662
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00825129
WT1 Wilms tumor 1 0.00817816
HIST1H2AC histone cluster 1, H2ac 0.00809388
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00805371
TYMP thymidine phosphorylase 0.00801488
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.00793468
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00791684
PRAME preferentially expressed antigen in melanoma 0.00778539
IFI16 interferon, gamma-inducible protein 16 0.00777993
TLR4 toll-like receptor 4 0.00771728
CP ceruloplasmin (ferroxidase) 0.00770389
RRAGD Ras-related GTP binding D 0.00763855
LY96 lymphocyte antigen 96 0.00762625
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00759742
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00752701
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 0.00751431
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.00738564
VGLL4 vestigial-like family member 4 0.0073137
COL4A5 collagen, type IV, alpha 5 0.00731284
KRT15 keratin 15, type I 0.00726141
NUPR1 nuclear protein, transcriptional regulator, 1 0.00725406
GPNMB glycoprotein (transmembrane) nmb 0.00722758
CTSA cathepsin A 0.00721718
GADD45A growth arrest and DNA-damage-inducible, alpha 0.0072072
SH3TC1 SH3 domain and tetratricopeptide repeats 1 0.00719073
ACTN1 actinin, alpha 1 0.00719014
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.00717508
SHB Src homology 2 domain containing adaptor protein B 0.00714868
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00714218
PFN2 profilin 2 0.00712182
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.00709141
CRYBG1 crystallin beta-gamma domain containing 1 0.00707928
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.00703807
GSTM3 glutathione S-transferase mu 3 (brain) 0.00703192
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00702781
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00698703
HOMER3 homer scaffolding protein 3 0.00697598
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00696927
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.00696338
ARL8B ADP-ribosylation factor-like 8B 0.006924
RIN2 Ras and Rab interactor 2 0.00690628
LAMB3 laminin, beta 3 0.00683385
DMXL2 Dmx-like 2 0.00677795
ITGAV integrin, alpha V 0.00676121
AKAP12 A kinase (PRKA) anchor protein 12 0.00675134
DPYD dihydropyrimidine dehydrogenase 0.00674988
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00673187
BRD4 bromodomain containing 4 0.00670685
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00670231
IL1RN interleukin 1 receptor antagonist 0.00669175
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00664744
AKAP8L A kinase (PRKA) anchor protein 8-like 0.00664255
FGB fibrinogen beta chain 0.00661058
PDE10A phosphodiesterase 10A 0.00660497
APOB apolipoprotein B 0.0065699
IGSF3 immunoglobulin superfamily, member 3 0.00656394
MT1G metallothionein 1G 0.0065621
ADA adenosine deaminase 0.00652574
GEM GTP binding protein overexpressed in skeletal muscle 0.00652268
LAMB1 laminin, beta 1 0.00649252
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00646909
SNAI2 snail family zinc finger 2 0.00643559
APOD apolipoprotein D 0.00641478
ACP3 acid phosphatase 3 0.00641469
EYA1 EYA transcriptional coactivator and phosphatase 1 0.0064018
HDAC9 histone deacetylase 9 0.00639355
YBX3 Y box binding protein 3 0.00639222
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00637231
NPAS2 neuronal PAS domain protein 2 0.00636939
HIST1H2BK histone cluster 1, H2bk 0.00636863
GBP2 guanylate binding protein 2, interferon-inducible 0.00633739
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00633126
HSPH1 heat shock 105kDa/110kDa protein 1 0.00631851
JAG1 jagged 1 0.00630186
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.00629883
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.00626014
MINK1 misshapen-like kinase 1 0.00623122
RRAD Ras-related associated with diabetes 0.00622204
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00621495
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.00620189
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.00620151
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.00618905
INAVA innate immunity activator 0.00618384
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 0.00614766
CXCL9 chemokine (C-X-C motif) ligand 9 0.00614589
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00614381
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00613853
SVIL supervillin 0.00613635
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.00612835
COPS7A COP9 signalosome subunit 7A 0.00610519
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.00609996
EXT1 exostosin glycosyltransferase 1 0.00609854
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.0060795
COL9A2 collagen, type IX, alpha 2 0.00604316
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.00602257
COL7A1 collagen, type VII, alpha 1 0.00596521
AKR1C3 aldo-keto reductase family 1, member C3 0.00594264
IGFBP1 insulin-like growth factor binding protein 1 0.00592649
CADM1 cell adhesion molecule 1 0.00592204
PAEP progestagen-associated endometrial protein 0.00591365
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00591248
DENND2B DENN domain containing 2B 0.00587513
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00585794
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.00585388
AKR1C2 aldo-keto reductase family 1, member C2 0.00585093
MBNL2 muscleblind-like splicing regulator 2 0.00583831
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00582452
AMDHD2 amidohydrolase domain containing 2 0.00581862
UPP1 uridine phosphorylase 1 0.0057986
USP3 ubiquitin specific peptidase 3 0.00578946
CRP C-reactive protein, pentraxin-related 0.00578004
RAB29 RAB29, member RAS oncogene family 0.00576599
PLXNB2 plexin B2 0.00576477
LAMC2 laminin, gamma 2 0.00575408
AFP alpha-fetoprotein 0.00574369
MLPH melanophilin 0.00572911
CLEC2B C-type lectin domain family 2, member B 0.00569944
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.00567972
ACSL3 acyl-CoA synthetase long-chain family member 3 0.00566852
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.00564976
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00564234
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00563164
MITF microphthalmia-associated transcription factor 0.00562861
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00561061
PLA1A phospholipase A1 member A 0.0056077
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00559704
KRT5 keratin 5, type II 0.00558388
PFKM phosphofructokinase, muscle 0.00557983
PYGB phosphorylase, glycogen; brain 0.00557132
SDCBP syndecan binding protein (syntenin) 0.00556293
TRIB1 tribbles pseudokinase 1 0.00555723
H1-2 H1.2 linker histone, cluster member 0.00554437
G6PD glucose-6-phosphate dehydrogenase 0.00553738
CSRP1 cysteine and glycine-rich protein 1 0.00553409
RIPK4 receptor-interacting serine-threonine kinase 4 0.00552127
SGCE sarcoglycan, epsilon 0.00551559
LDOC1 leucine zipper, down-regulated in cancer 1 0.00548586
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.00544824
COL4A6 collagen, type IV, alpha 6 0.00543883
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00543384
AGRN agrin 0.00540786
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.0053909
TXNRD1 thioredoxin reductase 1 0.00536806
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.00536668
AKR1C1 aldo-keto reductase family 1, member C1 0.00534461
TMEM51 transmembrane protein 51 0.00534193
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00533856
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.00533533
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.00532104
GABARAPL1 GABA(A) receptor-associated protein like 1 0.00531279
FAM110B family with sequence similarity 110, member B 0.00531238
EVC Ellis van Creveld protein 0.00530705
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00530571
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00529016
LYST lysosomal trafficking regulator 0.00528907
GLS glutaminase 0.00528015
PARP12 poly (ADP-ribose) polymerase family, member 12 0.00527838
SLC12A8 solute carrier family 12, member 8 0.00527777
OPN3 opsin 3 0.00526801
SNX7 sorting nexin 7 0.00526604
LIMK2 LIM domain kinase 2 0.00525408
AIM2 absent in melanoma 2 0.00523278
ERBB4 erb-b2 receptor tyrosine kinase 4 0.00522078
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.00521897
PMEPA1 prostate transmembrane protein, androgen induced 1 0.00520997
G0S2 G0/G1 switch 2 0.00520641
PEG3 paternally expressed 3 0.00520086
EFNA1 ephrin-A1 0.00517245
FAM114A1 family with sequence similarity 114, member A1 0.00516519
BASP1 brain abundant, membrane attached signal protein 1 0.00516343
SP100 SP100 nuclear antigen 0.00515131
FOSL2 FOS-like antigen 2 0.00513852
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00513717
FADS3 fatty acid desaturase 3 0.0051286
TRIB3 tribbles pseudokinase 3 0.00512809
HTRA1 HtrA serine peptidase 1 0.00511364
SMG7 SMG7 nonsense mediated mRNA decay factor 0.00510111
PRSS21 protease, serine, 21 (testisin) 0.00509941
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.00509887
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00508483
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.00508427
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.00507922
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00507596
PDZK1IP1 PDZK1 interacting protein 1 0.00507089
TUBA1A tubulin, alpha 1a 0.00506804
CRYAB crystallin, alpha B 0.00506365
OPTN optineurin 0.0050516
NPY neuropeptide Y 0.00503913
BAD BCL2-associated agonist of cell death 0.00503642
ABAT 4-aminobutyrate aminotransferase 0.00503343
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00503317
ZFP36L1 ZFP36 ring finger protein-like 1 0.00503071
SCGB2A1 secretoglobin, family 2A, member 1 0.00502855
TSPAN8 tetraspanin 8 0.00502844
FNDC3B fibronectin type III domain containing 3B 0.0050111
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.00500047
CXCL11 chemokine (C-X-C motif) ligand 11 0.00499303
MEIS1 Meis homeobox 1 0.0049837
DRAM1 DNA-damage regulated autophagy modulator 1 0.0049836
ETHE1 ethylmalonic encephalopathy 1 0.00497531
CD9 CD9 molecule 0.00496331
ISG20 interferon stimulated exonuclease gene 20kDa 0.00496152
IFI44 interferon-induced protein 44 0.00495572
NPC1 Niemann-Pick disease, type C1 0.00495254
LPIN1 lipin 1 0.00494956
SOAT1 sterol O-acyltransferase 1 0.00494632
PANK2 pantothenate kinase 2 0.00493637
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.00493393
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00492782
ZGPAT zinc finger, CCCH-type with G patch domain 0.00491042
INTS8 integrator complex subunit 8 0.00491022
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 0.00489168

decreased expression

Symbol Name Standardized Value
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.0179133
PRDX2 peroxiredoxin 2 -0.015312
MAP7 microtubule-associated protein 7 -0.0133408
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0130872
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.0127661
BMP4 bone morphogenetic protein 4 -0.0120528
SCD5 stearoyl-CoA desaturase 5 -0.0112658
OPHN1 oligophrenin 1 -0.0111765
CA2 carbonic anhydrase II -0.0106942
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0105081
HBB hemoglobin, beta -0.0105035
ADIRF adipogenesis regulatory factor -0.0103946
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.0103148
TFF3 trefoil factor 3 (intestinal) -0.0102961
OLFM1 olfactomedin 1 -0.00970456
CDCA4 cell division cycle associated 4 -0.00945943
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00939213
APOLD1 apolipoprotein L domain containing 1 -0.00934145
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00915712
TMSB15A thymosin beta 15a -0.00883074
AQP1 aquaporin 1 (Colton blood group) -0.00880946
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00878482
ANOS1 anosmin 1 -0.00861957
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -0.00856323
S100P S100 calcium binding protein P -0.00854722
HOPX HOP homeobox -0.00849397
EPCAM epithelial cell adhesion molecule -0.00833189
TCTA T-cell leukemia translocation altered -0.00817303
SCAMP1 secretory carrier membrane protein 1 -0.00814732
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00813514
FGFR3 fibroblast growth factor receptor 3 -0.00797278
PTCH1 patched 1 -0.00786418
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00784527
CIT citron rho-interacting serine/threonine kinase -0.00773051
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00772079
UGCG UDP-glucose ceramide glucosyltransferase -0.00762425
RPA3 replication protein A3, 14kDa -0.00757973
ESRP1 epithelial splicing regulatory protein 1 -0.00750756
MAT2A methionine adenosyltransferase II, alpha -0.00747269
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00735154
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00733813
PLK1 polo-like kinase 1 -0.00733524
KLK6 kallikrein-related peptidase 6 -0.00730854
RGS1 regulator of G-protein signaling 1 -0.00730847
AGTR1 angiotensin II receptor, type 1 -0.00727511
EGR2 early growth response 2 -0.00717833
KRT20 keratin 20, type I -0.00714996
CEMIP cell migration inducing protein, hyaluronan binding -0.00713512
TMEM38B transmembrane protein 38B -0.00711191
RCN2 reticulocalbin 2, EF-hand calcium binding domain -0.00710919
OIP5 Opa interacting protein 5 -0.00710603
CCNA2 cyclin A2 -0.00707311
TCTN2 tectonic family member 2 -0.00706797
PBK PDZ binding kinase -0.00702218
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00684208
SYT1 synaptotagmin I -0.00676525
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00675088
DEPDC1 DEP domain containing 1 -0.00673459
TYROBP TYRO protein tyrosine kinase binding protein -0.00669422
KIF20A kinesin family member 20A -0.00669219
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.006626
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00662583
EGR3 early growth response 3 -0.00659294
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.0065596
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00655008
CLDND1 claudin domain containing 1 -0.00654626
XYLT1 xylosyltransferase I -0.00650809
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00649053
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 -0.00647781
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00647571
TFDP1 transcription factor Dp-1 -0.00642243
LRRN3 leucine rich repeat neuronal 3 -0.00638941
HIGD1A HIG1 hypoxia inducible domain family, member 1A -0.0063512
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -0.00633136
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00629861
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00628825
SGPP1 sphingosine-1-phosphate phosphatase 1 -0.00627592
PRIM1 primase, DNA, polypeptide 1 (49kDa) -0.00622739
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00621216
RASA4 RAS p21 protein activator 4 -0.00620658
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00618137
CXADR coxsackie virus and adenovirus receptor -0.00616859
TUBGCP4 tubulin, gamma complex associated protein 4 -0.00615745
ADCY3 adenylate cyclase 3 -0.00615711
PSAT1 phosphoserine aminotransferase 1 -0.00610984
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.00610084
NTS neurotensin -0.00608982
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00608557
VSNL1 visinin-like 1 -0.00607752
KRT1 keratin 1, type II -0.00607721
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00605038
RCAN1 regulator of calcineurin 1 -0.00604917
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00604342
CPA3 carboxypeptidase A3 (mast cell) -0.00602638
BIRC5 baculoviral IAP repeat containing 5 -0.00599581
BMP7 bone morphogenetic protein 7 -0.00599447
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.00599252
SORD sorbitol dehydrogenase -0.0059883
AKAP7 A kinase (PRKA) anchor protein 7 -0.00598793
MAP2K6 mitogen-activated protein kinase kinase 6 -0.00597492
CES3 carboxylesterase 3 -0.00595113
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00594688
METTL7A methyltransferase like 7A -0.00591818
ADGRF5 adhesion G protein-coupled receptor F5 -0.00591636
FA2H fatty acid 2-hydroxylase -0.00591105
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -0.00590407
RBBP4 retinoblastoma binding protein 4 -0.00588896
GPA33 glycoprotein A33 (transmembrane) -0.00588527
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00588261
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa -0.00587993
NEK2 NIMA-related kinase 2 -0.00586632
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00586375
SPC25 SPC25, NDC80 kinetochore complex component -0.00586232
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -0.00585783
RNFT1 ring finger protein, transmembrane 1 -0.00584163
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00583205
EML4 echinoderm microtubule associated protein like 4 -0.00579501
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00579238
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00579165
SELENBP1 selenium binding protein 1 -0.00578404
FAR2 fatty acyl CoA reductase 2 -0.0057793
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00577567
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.0057552
MSLN mesothelin -0.0057493
CD302 CD302 molecule -0.00574193
BEX1 brain expressed, X-linked 1 -0.0057413
XK X-linked Kx blood group -0.00574079
MAB21L2 mab-21-like 2 (C. elegans) -0.00573156
TPGS2 tubulin polyglutamylase complex subunit 2 -0.00572059
ITGA6 integrin, alpha 6 -0.00570758
NPY1R neuropeptide Y receptor Y1 -0.00570406
TOB1 transducer of ERBB2, 1 -0.00569791
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.005697
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.00568077
FMO2 flavin containing monooxygenase 2 (non-functional) -0.00568002
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 -0.00567913
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00566468
CANX calnexin -0.00565349
FBXO11 F-box protein 11 -0.00564775
DCTN4 dynactin 4 (p62) -0.00564591
TMEM176B transmembrane protein 176B -0.00563486
NDUFA4 NDUFA4, mitochondrial complex associated -0.00563297
TUBB4B tubulin, beta 4B class IVb -0.00562551
SMC2 structural maintenance of chromosomes 2 -0.00562456
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 -0.00562352
CBR3 carbonyl reductase 3 -0.00562005
BAG1 BCL2-associated athanogene -0.00561637
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -0.00561605
NRN1 neuritin 1 -0.0056125
TXN thioredoxin -0.00560335
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00559104
PTBP3 polypyrimidine tract binding protein 3 -0.00559035
CH25H cholesterol 25-hydroxylase -0.00558943
LMAN1 lectin, mannose-binding, 1 -0.00557861
PMP2 peripheral myelin protein 2 -0.00552236
CLC Charcot-Leyden crystal galectin -0.00552053
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.00549702
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00549567
POSTN periostin, osteoblast specific factor -0.00549406
WDR61 WD repeat domain 61 -0.00549308
NUBPL nucleotide binding protein-like -0.00549023
CCL14 chemokine (C-C motif) ligand 14 -0.0054783
HMGB3 high mobility group box 3 -0.00547521
BDNF brain-derived neurotrophic factor -0.00545887
ATP5IF1 ATP synthase inhibitory factor subunit 1 -0.00543543
TUBB3 tubulin, beta 3 class III -0.00543086
TBCA tubulin folding cofactor A -0.00541473
NEIL3 nei endonuclease VIII-like 3 (E. coli) -0.00541132
TESC tescalcin -0.00537077
HSDL2 hydroxysteroid dehydrogenase like 2 -0.00536922
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 -0.00536326
COL14A1 collagen, type XIV, alpha 1 -0.00536125
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.0053598
PIGC phosphatidylinositol glycan anchor biosynthesis, class C -0.00535877
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -0.0053566
SET SET nuclear proto-oncogene -0.00533943
ZNF652 zinc finger protein 652 -0.00533629
UBE2S ubiquitin-conjugating enzyme E2S -0.00533287
GPM6B glycoprotein M6B -0.00531987
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -0.00531821
COX5A cytochrome c oxidase subunit Va -0.00530946
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -0.00529767
CARTPT CART prepropeptide -0.00528021
CD36 CD36 molecule (thrombospondin receptor) -0.00527905
GLO1 glyoxalase I -0.00526874
CENPX centromere protein X -0.00526659
RHOA ras homolog family member A -0.00526602
DMAC2L distal membrane arm assembly component 2 like -0.00526413
EXOC5 exocyst complex component 5 -0.00525027
RPL35 ribosomal protein L35 -0.00524807
DCLK1 doublecortin-like kinase 1 -0.00523646
KRCC1 lysine-rich coiled-coil 1 -0.00523306
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00522719
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.0052215
B3GNT1 -0.00521806
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00520497
PPA2 pyrophosphatase (inorganic) 2 -0.00519745
AK1 adenylate kinase 1 -0.00519486
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -0.00518921
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00518888
DLAT dihydrolipoamide S-acetyltransferase -0.00518535
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.0051701
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.00515339
KIF20B kinesin family member 20B -0.00514502
SMC1A structural maintenance of chromosomes 1A -0.00513598
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00513107
RFC5 replication factor C (activator 1) 5, 36.5kDa -0.00512067
FERMT1 fermitin family member 1 -0.00511327
UNG uracil-DNA glycosylase -0.00510094
EXPH5 exophilin 5 -0.00510033
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00508523
HOXC6 homeobox C6 -0.0050831
COBL cordon-bleu WH2 repeat protein -0.00507695
GOLGA8H golgin A8 family, member H -0.00504603
CLCA1 chloride channel accessory 1 -0.00503259
RGS5 regulator of G-protein signaling 5 -0.00500921
UGT8 UDP glycosyltransferase 8 -0.00500737
AQP4 aquaporin 4 -0.00499027
SRSF1 serine/arginine-rich splicing factor 1 -0.00497928
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -0.00497571
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -0.00497502
PER2 period circadian clock 2 -0.00496923
GPM6A glycoprotein M6A -0.00496438
ASF1B anti-silencing function 1B histone chaperone -0.00495585
TPBG trophoblast glycoprotein -0.00495323
APLNR apelin receptor -0.00495181
GPSM2 G-protein signaling modulator 2 -0.00494035
PTMA prothymosin, alpha -0.00493058
ZNF552 zinc finger protein 552 -0.00492362
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00491879
ADAM28 ADAM metallopeptidase domain 28 -0.00491441
SUMO3 small ubiquitin-like modifier 3 -0.00491018
PCYOX1 prenylcysteine oxidase 1 -0.00488922
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00488552
COX7B cytochrome c oxidase subunit VIIb -0.00487125
ARL5A ADP-ribosylation factor-like 5A -0.00487062
CDC6 cell division cycle 6 -0.00485698
SAMM50 SAMM50 sorting and assembly machinery component -0.0048567
PRKD3 protein kinase D3 -0.0048563
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00484645
HDAC6 histone deacetylase 6 -0.00484492
C1ORF56 chromosome 1 open reading frame 56 -0.00484402
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -0.00483664
CLU clusterin -0.00482571
CTNNA2 catenin (cadherin-associated protein), alpha 2 -0.00482534
CEP43 centrosomal protein 43 -0.00482373
ARHGAP19 Rho GTPase activating protein 19 -0.00481827
METTL5 methyltransferase like 5 -0.00481689
ZNF551 zinc finger protein 551 -0.00481122