| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | chemokine (C-C motif) ligand 5|This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] (NCBI Entrez Gene Database, 6352) |
| External Link | https://ncbi.nlm.nih.gov/gene/6352 |
| Similar Terms | |
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499 genes differentially expressed following the CCL5 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| S100A8 | S100 calcium binding protein A8 | 0.017594 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0153062 |
| PLK1 | polo-like kinase 1 | 0.0138598 |
| XPO7 | exportin 7 | 0.0125966 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0115742 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0111964 |
| NPTX2 | neuronal pentraxin II | 0.0111337 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.0108613 |
| S100A9 | S100 calcium binding protein A9 | 0.0107603 |
| HOPX | HOP homeobox | 0.0107113 |
| MAP7 | microtubule-associated protein 7 | 0.010427 |
| FCGBP | Fc fragment of IgG binding protein | 0.01033 |
| GNAS | GNAS complex locus | 0.0099763 |
| PROM1 | prominin 1 | 0.00964925 |
| OPHN1 | oligophrenin 1 | 0.00955647 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00952527 |
| STOM | stomatin | 0.00945261 |
| CD93 | CD93 molecule | 0.00919987 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00912812 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.0090677 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00905669 |
| LYZ | lysozyme | 0.00894318 |
| TSPAN13 | tetraspanin 13 | 0.00893045 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00872515 |
| RPA3 | replication protein A3, 14kDa | 0.00867055 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00860589 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00859752 |
| CDCA4 | cell division cycle associated 4 | 0.0085938 |
| NEBL | nebulette | 0.00849314 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00844813 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00838499 |
| FABP7 | fatty acid binding protein 7, brain | 0.00832427 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00813036 |
| MPZL2 | myelin protein zero-like 2 | 0.00805712 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00785515 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.00777811 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00777316 |
| TMSB15A | thymosin beta 15a | 0.00776554 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00772562 |
| SDC2 | syndecan 2 | 0.00772165 |
| PCLAF | PCNA clamp associated factor | 0.00771483 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00768545 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.00766712 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 0.00764827 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00762666 |
| CCNC | cyclin C | 0.00760485 |
| KIF20A | kinesin family member 20A | 0.00759329 |
| REEP1 | receptor accessory protein 1 | 0.00754401 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00752233 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | 0.00751725 |
| MLF1 | myeloid leukemia factor 1 | 0.00748852 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00748146 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00744586 |
| THBD | thrombomodulin | 0.00742982 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00741672 |
| PLSCR4 | phospholipid scramblase 4 | 0.00736803 |
| CCNA2 | cyclin A2 | 0.0073418 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.00732527 |
| SKP1 | S-phase kinase-associated protein 1 | 0.00729604 |
| TUSC3 | tumor suppressor candidate 3 | 0.00729368 |
| CD200 | CD200 molecule | 0.0072417 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00721181 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00720223 |
| FRZB | frizzled-related protein | 0.00717584 |
| COMMD10 | COMM domain containing 10 | 0.00715347 |
| TMEM47 | transmembrane protein 47 | 0.00714471 |
| CD34 | CD34 molecule | 0.00712097 |
| ANOS1 | anosmin 1 | 0.00710031 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00708701 |
| HMGB2 | high mobility group box 2 | 0.0070473 |
| PLP1 | proteolipid protein 1 | 0.00704532 |
| LAMA4 | laminin, alpha 4 | 0.00704381 |
| PBK | PDZ binding kinase | 0.00704311 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00702176 |
| WDR61 | WD repeat domain 61 | 0.0069964 |
| GMFG | glia maturation factor, gamma | 0.00697502 |
| MRPL39 | mitochondrial ribosomal protein L39 | 0.00697488 |
| SLC35A5 | solute carrier family 35, member A5 | 0.00697396 |
| ACKR3 | atypical chemokine receptor 3 | 0.00696343 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00696123 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 0.00695464 |
| TMEM14B | transmembrane protein 14B | 0.00692499 |
| RDX | radixin | 0.00692022 |
| SRGN | serglycin | 0.00691093 |
| FZD6 | frizzled class receptor 6 | 0.00688638 |
| S100A7 | S100 calcium binding protein A7 | 0.00687988 |
| DEK | DEK proto-oncogene | 0.00685578 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00681739 |
| MGP | matrix Gla protein | 0.00681513 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00679411 |
| HOXA5 | homeobox A5 | 0.00678507 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00677221 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00676811 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00676716 |
| TFDP1 | transcription factor Dp-1 | 0.00675971 |
| TXNIP | thioredoxin interacting protein | 0.00675003 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.0067484 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.0067477 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00673911 |
| CALD1 | caldesmon 1 | 0.00673678 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00673279 |
| HPF1 | histone PARylation factor 1 | 0.00671291 |
| S100B | S100 calcium binding protein B | 0.00670105 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00669953 |
| SNX10 | sorting nexin 10 | 0.00668366 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00666189 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00665572 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00664871 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00664089 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0065839 |
| HBB | hemoglobin, beta | 0.00654176 |
| VDAC3 | voltage-dependent anion channel 3 | 0.00652525 |
| PLPBP | pyridoxal phosphate binding protein | 0.00652082 |
| LAPTM5 | lysosomal protein transmembrane 5 | 0.00651892 |
| COPS4 | COP9 signalosome subunit 4 | 0.00651353 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00650704 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.00650496 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.00649756 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00645879 |
| TMX1 | thioredoxin-related transmembrane protein 1 | 0.00645817 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00644941 |
| MOCS2 | molybdenum cofactor synthesis 2 | 0.0064462 |
| KLHL23 | kelch-like family member 23 | 0.00641494 |
| DEPDC1 | DEP domain containing 1 | 0.00641251 |
| TPM4 | tropomyosin 4 | 0.00640466 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00640455 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00639851 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.00639202 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.00638984 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00637955 |
| OLFM1 | olfactomedin 1 | 0.00635927 |
| SELENOW | selenoprotein W | 0.00634529 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00633534 |
| RGCC | regulator of cell cycle | 0.00631326 |
| SPRR1B | small proline-rich protein 1B | 0.00630298 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00628753 |
| EMP2 | epithelial membrane protein 2 | 0.00628408 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00627594 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.00626001 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00624831 |
| BARD1 | BRCA1 associated RING domain 1 | 0.00622 |
| CA4 | carbonic anhydrase IV | 0.0062128 |
| ESD | esterase D | 0.00619603 |
| PRKD3 | protein kinase D3 | 0.00619273 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00615692 |
| MEF2C | myocyte enhancer factor 2C | 0.00615059 |
| HSBP1 | heat shock factor binding protein 1 | 0.00614238 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00611394 |
| TSPAN6 | tetraspanin 6 | 0.00609481 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.00609091 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00608098 |
| TIPRL | TOR signaling pathway regulator | 0.00603619 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | 0.00602546 |
| IFT52 | intraflagellar transport 52 | 0.00598844 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00597799 |
| TMEM45A | transmembrane protein 45A | 0.0059489 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.0059441 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00593861 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00593516 |
| ANGPT2 | angiopoietin 2 | 0.00593066 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | 0.0059248 |
| PRELID3B | PRELI domain containing 3B | 0.00591031 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00590702 |
| PLN | phospholamban | 0.00590377 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00590331 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00589707 |
| DCK | deoxycytidine kinase | 0.00589563 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00587613 |
| CDK1 | cyclin-dependent kinase 1 | 0.00585691 |
| TYRP1 | tyrosinase-related protein 1 | 0.00585166 |
| DHFR | dihydrofolate reductase | 0.00584189 |
| LMAN1 | lectin, mannose-binding, 1 | 0.00582169 |
| METRN | meteorin, glial cell differentiation regulator | 0.0058208 |
| HMGN1 | high mobility group nucleosome binding domain 1 | 0.00580689 |
| CBFB | core-binding factor, beta subunit | 0.005798 |
| CFI | complement factor I | 0.00579663 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | 0.00579563 |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 | 0.00577168 |
| CRIP2 | cysteine-rich protein 2 | 0.00577118 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.00576438 |
| TSPAN12 | tetraspanin 12 | 0.00576082 |
| PUDP | pseudouridine 5'-phosphatase | 0.0057605 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.00575914 |
| PLS3 | plastin 3 | 0.00575589 |
| MANSC1 | MANSC domain containing 1 | 0.00573729 |
| VBP1 | von Hippel-Lindau binding protein 1 | 0.00571478 |
| PRDX3 | peroxiredoxin 3 | 0.00571177 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00569349 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00569263 |
| TYROBP | TYRO protein tyrosine kinase binding protein | 0.00569023 |
| CRYZ | crystallin, zeta (quinone reductase) | 0.00568734 |
| CPE | carboxypeptidase E | 0.00566549 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00566118 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00564961 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00563173 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.0056307 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.00562398 |
| FHL1 | four and a half LIM domains 1 | 0.00560866 |
| EXOC5 | exocyst complex component 5 | 0.005607 |
| SLC2A4RG | SLC2A4 regulator | 0.00558149 |
| ERLIN2 | ER lipid raft associated 2 | 0.00557126 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.00556241 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.00556069 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00555225 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00553477 |
| RGS5 | regulator of G-protein signaling 5 | 0.00552376 |
| KLHDC3 | kelch domain containing 3 | 0.00552181 |
| CYTL1 | cytokine-like 1 | 0.00551959 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.00551958 |
| MEOX2 | mesenchyme homeobox 2 | 0.00551713 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.00551696 |
| CBX3 | chromobox homolog 3 | 0.005504 |
| KARS1 | lysyl-tRNA synthetase 1 | 0.00549245 |
| SUMO3 | small ubiquitin-like modifier 3 | 0.00549199 |
| ITM2A | integral membrane protein 2A | 0.00548967 |
| ANKRD46 | ankyrin repeat domain 46 | 0.00548857 |
| PTTG1 | pituitary tumor-transforming 1 | 0.00548526 |
| CDCA3 | cell division cycle associated 3 | 0.00548326 |
| PODXL | podocalyxin-like | 0.00548259 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit | 0.00547886 |
| SRM | spermidine synthase | 0.00546546 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.00546518 |
| CLCA4 | chloride channel accessory 4 | 0.00545058 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00544891 |
| PTMA | prothymosin, alpha | 0.00543565 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.00543513 |
| CALR | calreticulin | 0.00540541 |
| TRIP13 | thyroid hormone receptor interactor 13 | 0.00540336 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00540192 |
| CEL | carboxyl ester lipase | 0.0053987 |
| MRPL20 | mitochondrial ribosomal protein L20 | 0.0053941 |
| S1PR1 | sphingosine-1-phosphate receptor 1 | 0.0053871 |
| NREP | neuronal regeneration related protein | 0.00537799 |
| GAS1 | growth arrest-specific 1 | 0.00537451 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.00536984 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00536372 |
| ALPL | alkaline phosphatase, liver/bone/kidney | 0.00535716 |
| SIRT5 | sirtuin 5 | 0.00535299 |
| SELL | selectin L | 0.00535297 |
| UFL1 | UFM1-specific ligase 1 | 0.00535146 |
| HMGB1 | high mobility group box 1 | 0.00534784 |
| KRT10 | keratin 10, type I | 0.00534771 |
| MDFIC | MyoD family inhibitor domain containing | 0.00533782 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00532406 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | 0.00532026 |
| CEP43 | centrosomal protein 43 | 0.00531728 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.005313 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.00531111 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00530877 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00529042 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0157076 |
| BMP4 | bone morphogenetic protein 4 | -0.0137665 |
| TSPAN8 | tetraspanin 8 | -0.0130344 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0129032 |
| POU2AF1 | POU class 2 associating factor 1 | -0.0125297 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0124742 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.0121099 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.0116327 |
| IRS2 | insulin receptor substrate 2 | -0.0114334 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0111966 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.010236 |
| KLK11 | kallikrein-related peptidase 11 | -0.00977292 |
| HMOX1 | heme oxygenase 1 | -0.00974206 |
| MMP7 | matrix metallopeptidase 7 | -0.00956522 |
| G0S2 | G0/G1 switch 2 | -0.00945529 |
| CALB1 | calbindin 1, 28kDa | -0.00925867 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00925113 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00919497 |
| LOXL1 | lysyl oxidase-like 1 | -0.00917997 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00914459 |
| KRT19 | keratin 19, type I | -0.00898668 |
| STC2 | stanniocalcin 2 | -0.00883211 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00863344 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00861194 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00852126 |
| CD9 | CD9 molecule | -0.00845655 |
| RNF167 | ring finger protein 167 | -0.008423 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -0.00837401 |
| HSPA2 | heat shock 70kDa protein 2 | -0.0083237 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00818034 |
| RRBP1 | ribosome binding protein 1 | -0.00815865 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00815216 |
| LAMB3 | laminin, beta 3 | -0.00815195 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00811072 |
| ATF4 | activating transcription factor 4 | -0.00808897 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00803128 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00789192 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00787653 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0078515 |
| JAG1 | jagged 1 | -0.00784034 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00784003 |
| PDGFC | platelet derived growth factor C | -0.0078096 |
| LARP6 | La ribonucleoprotein domain family, member 6 | -0.00778366 |
| RRAGD | Ras-related GTP binding D | -0.00776594 |
| H1-0 | H1.0 linker histone | -0.0077623 |
| TGFA | transforming growth factor, alpha | -0.00761319 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00761153 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00760588 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00752547 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.0075205 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00751825 |
| GAS6 | growth arrest-specific 6 | -0.00749046 |
| SPATA20 | spermatogenesis associated 20 | -0.00747924 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00746594 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00746109 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00745722 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00742477 |
| INHBA | inhibin, beta A | -0.00741996 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00738299 |
| DNMBP | dynamin binding protein | -0.00731516 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00728235 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | -0.00726842 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | -0.00724517 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00723725 |
| PLAU | plasminogen activator, urokinase | -0.00722913 |
| PSEN1 | presenilin 1 | -0.00717373 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00712129 |
| ZNF91 | zinc finger protein 91 | -0.00711423 |
| STK38 | serine/threonine kinase 38 | -0.00709734 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00708388 |
| REG1A | regenerating islet-derived 1 alpha | -0.00708343 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00708033 |
| TGM2 | transglutaminase 2 | -0.00707857 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00707259 |
| CAMTA2 | calmodulin binding transcription activator 2 | -0.00706121 |
| PDLIM4 | PDZ and LIM domain 4 | -0.00705952 |
| HEPH | hephaestin | -0.00704872 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00703272 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00701618 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | -0.00698156 |
| ODC1 | ornithine decarboxylase 1 | -0.00697616 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00697463 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00693716 |
| TPD52 | tumor protein D52 | -0.00692494 |
| PSAP | prosaposin | -0.00691301 |
| YBX3 | Y box binding protein 3 | -0.006902 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00688224 |
| SECISBP2L | SECIS binding protein 2-like | -0.0068621 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0068507 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.00671609 |
| PTK2 | protein tyrosine kinase 2 | -0.00671603 |
| LCN2 | lipocalin 2 | -0.00670131 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.00668393 |
| MVP | major vault protein | -0.0066317 |
| NKX3-1 | NK3 homeobox 1 | -0.00662666 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.00661896 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 | -0.00659606 |
| FADS3 | fatty acid desaturase 3 | -0.00653609 |
| FAM50A | family with sequence similarity 50, member A | -0.00653439 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.00650899 |
| LAMC2 | laminin, gamma 2 | -0.00647159 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.0064301 |
| WASHC4 | WASH complex subunit 4 | -0.00642701 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.00641597 |
| MSMB | microseminoprotein, beta- | -0.00640128 |
| FOSL2 | FOS-like antigen 2 | -0.00639891 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.00639887 |
| AOC1 | amine oxidase, copper containing 1 | -0.00639267 |
| RRAGA | Ras-related GTP binding A | -0.00639101 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00631247 |
| BLNK | B-cell linker | -0.0063114 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00630691 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00629041 |
| SIK3 | SIK family kinase 3 | -0.00628585 |
| LIF | leukemia inhibitory factor | -0.00624637 |
| DUSP5 | dual specificity phosphatase 5 | -0.00624477 |
| NEO1 | neogenin 1 | -0.00622694 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00622106 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00621905 |
| SQSTM1 | sequestosome 1 | -0.00621707 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | -0.00620531 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 | -0.00619894 |
| CD19 | CD19 molecule | -0.00619263 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00618736 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00617849 |
| ACTN1 | actinin, alpha 1 | -0.00616782 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00616143 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0061571 |
| ADRB2 | adrenoceptor beta 2, surface | -0.00614833 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00612924 |
| OPTN | optineurin | -0.0061289 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.00612552 |
| SMAD7 | SMAD family member 7 | -0.00612006 |
| MYRF | myelin regulatory factor | -0.00611315 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.00611229 |
| PRKCA | protein kinase C, alpha | -0.00611181 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 | -0.00610008 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00608609 |
| VGLL4 | vestigial-like family member 4 | -0.00607611 |
| PLXNA1 | plexin A1 | -0.00600639 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | -0.00598307 |
| ABHD4 | abhydrolase domain containing 4 | -0.0059698 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00596616 |
| NRBF2 | nuclear receptor binding factor 2 | -0.00596012 |
| PLXNB2 | plexin B2 | -0.00595927 |
| RETREG2 | reticulophagy regulator family member 2 | -0.00595705 |
| ZC3H12A | zinc finger CCCH-type containing 12A | -0.00594876 |
| CA12 | carbonic anhydrase XII | -0.00593443 |
| KCTD5 | potassium channel tetramerization domain containing 5 | -0.00593312 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.005931 |
| ERCC5 | excision repair cross-complementation group 5 | -0.00592563 |
| TRIB2 | tribbles pseudokinase 2 | -0.00592337 |
| JMJD1C | jumonji domain containing 1C | -0.0059136 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00591 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00590261 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00590099 |
| CCN3 | cellular communication network factor 3 | -0.00589659 |
| MCOLN1 | mucolipin 1 | -0.0058885 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00587904 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00586429 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | -0.00580875 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | -0.00579698 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.00578595 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | -0.00576462 |
| CDR2L | cerebellar degeneration-related protein 2-like | -0.00576221 |
| HOMER3 | homer scaffolding protein 3 | -0.00576053 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00573893 |
| AGR2 | anterior gradient 2 | -0.00573605 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | -0.0057067 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | -0.00569483 |
| MED13 | mediator complex subunit 13 | -0.00569387 |
| HIST1H2BH | histone cluster 1, H2bh | -0.0056937 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00569014 |
| FBLN1 | fibulin 1 | -0.00568502 |
| CD82 | CD82 molecule | -0.00568343 |
| PAEP | progestagen-associated endometrial protein | -0.00568038 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00567704 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | -0.00567658 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00567634 |
| TPP1 | tripeptidyl peptidase I | -0.00567579 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00566963 |
| GAB2 | GRB2-associated binding protein 2 | -0.00565862 |
| MLPH | melanophilin | -0.0056476 |
| CTBP2 | C-terminal binding protein 2 | -0.00564641 |
| TLE4 | transducin-like enhancer of split 4 | -0.0056453 |
| PAX5 | paired box 5 | -0.00563704 |
| USP47 | ubiquitin specific peptidase 47 | -0.00562763 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00561637 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00561403 |
| CUX1 | cut-like homeobox 1 | -0.00561227 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.00560629 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.00560543 |
| TPST2 | tyrosylprotein sulfotransferase 2 | -0.00560329 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 | -0.00559651 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.00559362 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | -0.00559265 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.00558934 |
| HIP1R | huntingtin interacting protein 1 related | -0.00556836 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.00556393 |
| GSDME | gasdermin E | -0.00555984 |
| GPR137B | G protein-coupled receptor 137B | -0.00555621 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -0.00554967 |
| TUFT1 | tuftelin 1 | -0.00554441 |
| NOTCH2 | notch 2 | -0.00550957 |
| YARS1 | tyrosyl-tRNA synthetase 1 | -0.00550281 |
| ITGB4 | integrin, beta 4 | -0.00549642 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00548984 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00548826 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00548768 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00548283 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | -0.00547933 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.00547667 |
| TRIB3 | tribbles pseudokinase 3 | -0.00547593 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | -0.00547057 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00545691 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | -0.00545123 |
| LYST | lysosomal trafficking regulator | -0.0054512 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00542477 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00541461 |
| IPO13 | importin 13 | -0.00539527 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00538823 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.00538337 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.00538112 |
| TUG1 | taurine up-regulated 1 (non-protein coding) | -0.00537734 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00536479 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 | -0.00535953 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.00535645 |
| PLXNA3 | plexin A3 | -0.0053521 |
| NPC2 | Niemann-Pick disease, type C2 | -0.00534683 |
| KLK2 | kallikrein-related peptidase 2 | -0.0053454 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00533697 |
| BRD4 | bromodomain containing 4 | -0.005336 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00532816 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.00532648 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0053228 |
| GOLGB1 | golgin B1 | -0.00530453 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.00529517 |
| NADSYN1 | NAD synthetase 1 | -0.00528699 |
| H1-2 | H1.2 linker histone, cluster member | -0.00528634 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00527647 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0052729 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00526017 |
| CLCN7 | chloride channel, voltage-sensitive 7 | -0.00525827 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | -0.00524501 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00524385 |
| FTSJ3 | FtsJ homolog 3 (E. coli) | -0.0052404 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.00522253 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | -0.00521855 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00521691 |
