CCL7 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description chemokine (C-C motif) ligand 7|This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6354)
External Link http://www.ncbi.nlm.nih.gov/gene/6354
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Genes

15 interacting proteins for CCL7 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AES amino-terminal enhancer of split
CCR1 chemokine (C-C motif) receptor 1
CCR10 chemokine (C-C motif) receptor 10
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CXCR3 chemokine (C-X-C motif) receptor 3
ELAVL1 ELAV like RNA binding protein 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GRK6 G protein-coupled receptor kinase 6
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3