CCL8 Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description chemokine (C-C motif) ligand 8|This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 6355)
External Link https://dgidb.org/results?searchType=drug&searchTerms=CCL8
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5 interacting proteins for the CCL8 drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
CCR8 chemokine (C-C motif) receptor 8 1.51234
CCR1 chemokine (C-C motif) receptor 1 0.341497
CCR3 chemokine (C-C motif) receptor 3 0.311365
CCR2 chemokine (C-C motif) receptor 2 0.199743
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.199743