CCL8 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description chemokine (C-C motif) ligand 8|This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 6355)
External Link https://ncbi.nlm.nih.gov/gene/6355
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Genes

500 genes differentially expressed following the CCL8 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
NVL nuclear VCP-like 0.0141305
DEGS1 delta(4)-desaturase, sphingolipid 1 0.0130424
TOX3 TOX high mobility group box family member 3 0.0119129
WT1 Wilms tumor 1 0.0112758
BTG3 BTG family, member 3 0.0111433
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.0109605
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0107989
CHKB choline kinase beta 0.0107726
CHGB chromogranin B 0.0105548
PEG10 paternally expressed 10 0.00992923
KCTD12 potassium channel tetramerization domain containing 12 0.00979002
PIP prolactin-induced protein 0.00961987
DEFB1 defensin, beta 1 0.00960397
CCNB1 cyclin B1 0.00944052
CDCP1 CUB domain containing protein 1 0.00940303
NELL2 NEL-like 2 (chicken) 0.00940247
NCAM1 neural cell adhesion molecule 1 0.00925929
TMEM45A transmembrane protein 45A 0.0090708
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00903022
PLAT plasminogen activator, tissue 0.00880198
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00870278
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00866883
SNX7 sorting nexin 7 0.00865356
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00853717
ZNF395 zinc finger protein 395 0.0085348
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00843455
CCR2 chemokine (C-C motif) receptor 2 0.00840494
MAMLD1 mastermind-like domain containing 1 0.00838344
EVI2A ecotropic viral integration site 2A 0.00831233
GAS6 growth arrest-specific 6 0.00830164
SPON1 spondin 1, extracellular matrix protein 0.00819476
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00817951
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00816273
CLGN calmegin 0.00815865
VLDLR very low density lipoprotein receptor 0.00815011
CXCL8 chemokine (C-X-C motif) ligand 8 0.00808846
BHLHE41 basic helix-loop-helix family, member e41 0.00803414
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00799185
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.00788769
CDC45 cell division cycle 45 0.00788428
SST somatostatin 0.0078765
COL4A5 collagen, type IV, alpha 5 0.00774268
HOXB2 homeobox B2 0.00773742
GRB14 growth factor receptor-bound protein 14 0.0076806
SNAI2 snail family zinc finger 2 0.00767449
CD14 CD14 molecule 0.00766903
LPAR6 lysophosphatidic acid receptor 6 0.00764651
ZNF331 zinc finger protein 331 0.00762359
ITPRID2 ITPR interacting domain containing 2 0.0075279
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00751891
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00751797
C3 complement component 3 0.0074288
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00737616
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.00736893
CLEC2B C-type lectin domain family 2, member B 0.00734062
NELL1 NEL-like 1 (chicken) 0.00724788
SLIT2 slit homolog 2 (Drosophila) 0.00719409
GPM6B glycoprotein M6B 0.00719232
PDZK1IP1 PDZK1 interacting protein 1 0.00717073
PRAME preferentially expressed antigen in melanoma 0.00713033
PAEP progestagen-associated endometrial protein 0.00712348
VEGFA vascular endothelial growth factor A 0.00708726
SCG5 secretogranin V 0.00708552
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00708386
CAPN2 calpain 2, (m/II) large subunit 0.00707967
MOCOS molybdenum cofactor sulfurase 0.00706488
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.00703918
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.00701332
RNF130 ring finger protein 130 0.006965
HBEGF heparin-binding EGF-like growth factor 0.00688004
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.00683189
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.00680868
CDA cytidine deaminase 0.00680344
ASS1 argininosuccinate synthase 1 0.00680302
LCN2 lipocalin 2 0.00676603
LIF leukemia inhibitory factor 0.00675318
DHRS7 dehydrogenase/reductase (SDR family) member 7 0.00674242
LRRN3 leucine rich repeat neuronal 3 0.00673292
CLDN8 claudin 8 0.00672927
LTF lactotransferrin 0.00669581
SRPX sushi-repeat containing protein, X-linked 0.00664639
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.0065782
INHBA inhibin, beta A 0.00657628
TGM2 transglutaminase 2 0.00655221
AGO3 argonaute RISC catalytic component 3 0.00654548
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00653637
FABP1 fatty acid binding protein 1, liver 0.00653387
S100A7 S100 calcium binding protein A7 0.00649065
TUBB2A tubulin, beta 2A class IIa 0.00648838
XCL1 chemokine (C motif) ligand 1 0.00648521
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00647679
PDZK1 PDZ domain containing 1 0.00647168
GSTA1 glutathione S-transferase alpha 1 0.00646378
CYBRD1 cytochrome b reductase 1 0.00642186
CCP110 centriolar coiled coil protein 110kDa 0.00642011
PBX3 pre-B-cell leukemia homeobox 3 0.0064069
MFAP5 microfibrillar associated protein 5 0.00638455
CERS2 ceramide synthase 2 0.00638113
CYTIP cytohesin 1 interacting protein 0.00635708
AMIGO2 adhesion molecule with Ig-like domain 2 0.0063296
KRT81 keratin 81, type II 0.00629796
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0062928
KLK6 kallikrein-related peptidase 6 0.00628955
MTARC2 mitochondrial amidoxime reducing component 2 0.00628711
GPR183 G protein-coupled receptor 183 0.00627578
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 0.00627436
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00625184
GCG glucagon 0.00623614
TXNDC9 thioredoxin domain containing 9 0.00622331
EGLN3 egl-9 family hypoxia-inducible factor 3 0.00622056
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00621759
INSM1 insulinoma-associated 1 0.00618834
CIB1 calcium and integrin binding 1 (calmyrin) 0.00617798
TCF21 transcription factor 21 0.00617447
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.00616775
FHOD3 formin homology 2 domain containing 3 0.00616409
IL1B interleukin 1, beta 0.00615707
REEP1 receptor accessory protein 1 0.00612237
COPA coatomer protein complex, subunit alpha 0.00612099
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 0.00609516
F12 coagulation factor XII (Hageman factor) 0.00604423
BCHE butyrylcholinesterase 0.00603258
RGS2 regulator of G-protein signaling 2 0.00602732
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0060004
PICALM phosphatidylinositol binding clathrin assembly protein 0.00597649
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.00596539
BBX bobby sox homolog (Drosophila) 0.0059369
RNF139 ring finger protein 139 0.00589636
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.00589349
KCTD5 potassium channel tetramerization domain containing 5 0.00588307
CCL4 chemokine (C-C motif) ligand 4 0.00587634
BAG2 BCL2-associated athanogene 2 0.00587143
PBLD phenazine biosynthesis-like protein domain containing 0.00584398
AREG amphiregulin 0.00583944
CST6 cystatin E/M 0.00581121
ECI2 enoyl-CoA delta isomerase 2 0.00581096
RORA RAR-related orphan receptor A 0.00580793
SOSTDC1 sclerostin domain containing 1 0.00580536
LAMB1 laminin, beta 1 0.00580247
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.0057968
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00579408
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00579112
CHGA chromogranin A 0.00579081
CXCR4 chemokine (C-X-C motif) receptor 4 0.0057636
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00575147
CCDC86 coiled-coil domain containing 86 0.00573808
GPR65 G protein-coupled receptor 65 0.00573591
GSDME gasdermin E 0.00571756
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.00571222
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.00570898
FBXO28 F-box protein 28 0.00570195
MYRF myelin regulatory factor 0.0056933
IL10RA interleukin 10 receptor, alpha 0.0056834
NT5E 5'-nucleotidase, ecto (CD73) 0.00567682
ZBED2 zinc finger, BED-type containing 2 0.00565623
GDE1 glycerophosphodiester phosphodiesterase 1 0.00565558
DOCK4 dedicator of cytokinesis 4 0.00565103
HCRT hypocretin (orexin) neuropeptide precursor 0.00564967
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 0.00564427
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.00564405
PRSS21 protease, serine, 21 (testisin) 0.00561408
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00560775
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00560525
FPR3 formyl peptide receptor 3 0.00558688
AADAC arylacetamide deacetylase 0.00557953
BAD BCL2-associated agonist of cell death 0.0055727
COG2 component of oligomeric golgi complex 2 0.00556653
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.00556082
PIEZO2 piezo-type mechanosensitive ion channel component 2 0.00556075
PLAU plasminogen activator, urokinase 0.00555804
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.00555601
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00555459
INHBB inhibin, beta B 0.00554849
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00552251
TMEM100 transmembrane protein 100 0.00551716
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00551594
SOX11 SRY (sex determining region Y)-box 11 0.00549994
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00549518
KDM3A lysine (K)-specific demethylase 3A 0.00549478
GLIPR1 GLI pathogenesis-related 1 0.00549186
SGCE sarcoglycan, epsilon 0.00545775
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00545348
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00542771
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00541822
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.00539897
LAMC2 laminin, gamma 2 0.00539142
PEG3 paternally expressed 3 0.00539122
TGFA transforming growth factor, alpha 0.00536561
FDX1 ferredoxin 1 0.00535833
TFPI2 tissue factor pathway inhibitor 2 0.00535238
RAB4A RAB4A, member RAS oncogene family 0.00534251
DUSP10 dual specificity phosphatase 10 0.00534042
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00532482
GUCA2A guanylate cyclase activator 2A (guanylin) 0.00531995
HOXB7 homeobox B7 0.00531944
PODXL podocalyxin-like 0.00531437
NUSAP1 nucleolar and spindle associated protein 1 0.00530713
ST18 suppression of tumorigenicity 18, zinc finger 0.0052879
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.00528331
CXADR coxsackie virus and adenovirus receptor 0.00528059
KLK10 kallikrein-related peptidase 10 0.00526936
COTL1 coactosin-like F-actin binding protein 1 0.00526482
CCL13 chemokine (C-C motif) ligand 13 0.00525598
VNN1 vanin 1 0.00525042
LGALS2 lectin, galactoside-binding, soluble, 2 0.00524075
RHOBTB3 Rho-related BTB domain containing 3 0.00523781
ESRRG estrogen-related receptor gamma 0.00523316
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.00523171
CAV2 caveolin 2 0.00520839
ADGRF5 adhesion G protein-coupled receptor F5 0.00520255
COL4A6 collagen, type IV, alpha 6 0.00518639
PLEK2 pleckstrin 2 0.00517605
HLTF helicase-like transcription factor 0.0051624
POSTN periostin, osteoblast specific factor 0.00515435
TSPAN12 tetraspanin 12 0.0051474
NRIP1 nuclear receptor interacting protein 1 0.00514185
HSPA13 heat shock protein 70kDa family, member 13 0.00513737
RTN1 reticulon 1 0.00513218
TH tyrosine hydroxylase 0.00511734
FJX1 four jointed box 1 (Drosophila) 0.00510871
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.00509732
HOXA5 homeobox A5 0.00509428
SLC38A10 solute carrier family 38, member 10 0.0050822
ELP5 elongator acetyltransferase complex subunit 5 0.00508207
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00507095
FKBP2 FK506 binding protein 2, 13kDa 0.00506853
PRNP prion protein 0.00506556
GPX3 glutathione peroxidase 3 0.00505982
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.00505972
SAC3D1 SAC3 domain containing 1 0.00505911
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00504941
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.00504252
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.00503198
CHD9 chromodomain helicase DNA binding protein 9 0.00500799
CLIC5 chloride intracellular channel 5 0.00499964
BIRC3 baculoviral IAP repeat containing 3 0.00499666
CADM1 cell adhesion molecule 1 0.00498997
LITAF lipopolysaccharide-induced TNF factor 0.00498643
CD2 CD2 molecule 0.00498519
SAMHD1 SAM domain and HD domain 1 0.00497576
CSRP2 cysteine and glycine-rich protein 2 0.00496988
CSF1R colony stimulating factor 1 receptor 0.00496567
ACSF2 acyl-CoA synthetase family member 2 0.00496263
NXN nucleoredoxin 0.00495967
KLK8 kallikrein-related peptidase 8 0.00494974
CYC1 cytochrome c-1 0.00494184
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.00493867
CKAP4 cytoskeleton-associated protein 4 0.00492912
CALML5 calmodulin-like 5 0.00491835
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.00491779

decreased expression

Symbol Name Standardized Value
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0139003
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0136779
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.0119643
CNTN1 contactin 1 -0.0101323
LMO3 LIM domain only 3 (rhombotin-like 2) -0.0099356
VDAC1 voltage-dependent anion channel 1 -0.00956714
S100A8 S100 calcium binding protein A8 -0.00930382
GPNMB glycoprotein (transmembrane) nmb -0.00925662
IFITM1 interferon induced transmembrane protein 1 -0.00918155
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00911869
TESC tescalcin -0.00910787
BEX1 brain expressed, X-linked 1 -0.00898482
DRAM1 DNA-damage regulated autophagy modulator 1 -0.00883492
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00881139
TACSTD2 tumor-associated calcium signal transducer 2 -0.00876906
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00874351
BMP7 bone morphogenetic protein 7 -0.00873183
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -0.00866483
DKK3 dickkopf WNT signaling pathway inhibitor 3 -0.00862828
NRN1 neuritin 1 -0.00852322
MYBPC1 myosin binding protein C, slow type -0.00850949
VWF von Willebrand factor -0.00846829
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -0.00833368
C10ORF10 chromosome 10 open reading frame 10 -0.00832167
WEE1 WEE1 G2 checkpoint kinase -0.00825555
LYZ lysozyme -0.00820391
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00819969
RAI14 retinoic acid induced 14 -0.00819878
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00813651
TSPAN13 tetraspanin 13 -0.00810026
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00808898
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.0080784
CRYBG1 crystallin beta-gamma domain containing 1 -0.0080738
MSX1 msh homeobox 1 -0.00807352
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00798194
GSPT2 G1 to S phase transition 2 -0.00789247
SNAP25 synaptosomal-associated protein, 25kDa -0.00789043
MT1E metallothionein 1E -0.00787158
TPM4 tropomyosin 4 -0.00784641
IFITM2 interferon induced transmembrane protein 2 -0.00774938
FGFR3 fibroblast growth factor receptor 3 -0.00772273
NBEAL2 neurobeachin-like 2 -0.00763409
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.00757965
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.00757221
KRT13 keratin 13, type I -0.00753527
TRIM22 tripartite motif containing 22 -0.00751631
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.00750766
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.00736278
FCGRT Fc fragment of IgG, receptor, transporter, alpha -0.00735771
PER2 period circadian clock 2 -0.00733251
TSPAN8 tetraspanin 8 -0.00730776
FBLN2 fibulin 2 -0.00723286
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00722718
SFTPA2 surfactant protein A2 -0.00721173
WDR61 WD repeat domain 61 -0.00720378
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00719706
ICAM2 intercellular adhesion molecule 2 -0.00718168
C2CD5 C2 calcium-dependent domain containing 5 -0.00716631
MTCL1 microtubule crosslinking factor 1 -0.00714977
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.00712513
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00708264
TFF3 trefoil factor 3 (intestinal) -0.00707231
GPX2 glutathione peroxidase 2 -0.00699701
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0069949
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -0.00698375
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -0.00694918
CEMIP cell migration inducing protein, hyaluronan binding -0.00692655
CST3 cystatin C -0.00690744
SELL selectin L -0.00686176
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00682896
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00681636
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.00681112
ADIRF adipogenesis regulatory factor -0.00681018
CLU clusterin -0.00678727
DACH1 dachshund family transcription factor 1 -0.00670525
NDRG2 NDRG family member 2 -0.00670445
CCK cholecystokinin -0.00669276
NNMT nicotinamide N-methyltransferase -0.00667639
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.00666039
RTN2 reticulon 2 -0.00662114
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00660975
E2F2 E2F transcription factor 2 -0.00659959
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -0.00658778
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00658588
PLBD1 phospholipase B domain containing 1 -0.00656868
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00656016
GSAP gamma-secretase activating protein -0.00655014
ZCCHC2 zinc finger, CCHC domain containing 2 -0.00651222
NRGN neurogranin (protein kinase C substrate, RC3) -0.00648383
CYTL1 cytokine-like 1 -0.00646659
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00641487
NLRP2 NLR family, pyrin domain containing 2 -0.00641379
RAB29 RAB29, member RAS oncogene family -0.00637233
TRIB3 tribbles pseudokinase 3 -0.00631021
ATP9A ATPase, class II, type 9A -0.00629504
SELENOW selenoprotein W -0.00626678
EPAS1 endothelial PAS domain protein 1 -0.00624678
COCH cochlin -0.00623078
SPRR3 small proline-rich protein 3 -0.00619742
GMDS GDP-mannose 4,6-dehydratase -0.00619723
LEFTY1 left-right determination factor 1 -0.00619679
STK39 serine threonine kinase 39 -0.00618849
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -0.00617091
HEXB hexosaminidase B (beta polypeptide) -0.00615186
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 -0.00611703
AQP1 aquaporin 1 (Colton blood group) -0.00611506
TRIP6 thyroid hormone receptor interactor 6 -0.00611455
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.00610554
PF4 platelet factor 4 -0.00609077
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00608138
TNS3 tensin 3 -0.00606876
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00605043
CALML3 calmodulin-like 3 -0.00600918
MELK maternal embryonic leucine zipper kinase -0.00599686
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.0059822
ERLIN2 ER lipid raft associated 2 -0.00594679
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00590586
TM4SF1 transmembrane 4 L six family member 1 -0.00589421
TMPRSS11E transmembrane protease, serine 11E -0.0058844
TP63 tumor protein p63 -0.00583195
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00582149
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00580102
SEPP1 selenoprotein P, plasma, 1 -0.00579541
SMAGP small cell adhesion glycoprotein -0.00579169
ALPL alkaline phosphatase, liver/bone/kidney -0.00578186
PKP1 plakophilin 1 -0.0057809
SPRR1B small proline-rich protein 1B -0.00576617
PUDP pseudouridine 5'-phosphatase -0.00575123
PXDN peroxidasin -0.0057511
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa -0.00573384
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.00573205
ZNF589 zinc finger protein 589 -0.00572341
FBXO34 F-box protein 34 -0.00572078
MMP9 matrix metallopeptidase 9 -0.00571745
SLN sarcolipin -0.00568937
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -0.0056754
TGIF1 TGFB-induced factor homeobox 1 -0.00567493
TMEM176B transmembrane protein 176B -0.00564232
NEBL nebulette -0.00564012
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00563528
NOTCH1 notch 1 -0.00561801
MT1H metallothionein 1H -0.00559907
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00559851
IL1RN interleukin 1 receptor antagonist -0.0055853
EPHB3 EPH receptor B3 -0.0055744
CYRIA CYFIP related Rac1 interactor A -0.00557356
SPRR1A small proline-rich protein 1A -0.00556516
FRY furry homolog (Drosophila) -0.00556282
RPIA ribose 5-phosphate isomerase A -0.00556063
DLX5 distal-less homeobox 5 -0.00554795
TAGLN transgelin -0.00553855
FBN2 fibrillin 2 -0.00552515
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -0.005522
SMYD3 SET and MYND domain containing 3 -0.0054968
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.00548199
AVL9 AVL9 homolog (S. cerevisiase) -0.00548121
ZMYM2 zinc finger, MYM-type 2 -0.00547998
CSTA cystatin A (stefin A) -0.00547738
PWP1 PWP1 homolog (S. cerevisiae) -0.00546149
TRH thyrotropin-releasing hormone -0.00545064
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -0.00544208
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.0054396
TMPRSS4 transmembrane protease, serine 4 -0.00543854
KRAS Kirsten rat sarcoma viral oncogene homolog -0.005424
C1ORF54 chromosome 1 open reading frame 54 -0.00540868
HSPB8 heat shock 22kDa protein 8 -0.00539891
COL2A1 collagen, type II, alpha 1 -0.00534598
KIAA0226L KIAA0226-like -0.00533991
PLPBP pyridoxal phosphate binding protein -0.00533903
CAB39 calcium binding protein 39 -0.005332
GLO1 glyoxalase I -0.00532069
NOTCH3 notch 3 -0.00530923
IER2 immediate early response 2 -0.0053072
OLFM1 olfactomedin 1 -0.00530596
NFE2L2 nuclear factor, erythroid 2-like 2 -0.00530453
WIF1 WNT inhibitory factor 1 -0.00529906
PELI1 pellino E3 ubiquitin protein ligase 1 -0.0052949
PPT1 palmitoyl-protein thioesterase 1 -0.00528113
MME membrane metallo-endopeptidase -0.00527768
ZNF106 zinc finger protein 106 -0.00526379
CD81 CD81 molecule -0.00525974
CRISP3 cysteine-rich secretory protein 3 -0.00525743
LARP4B La ribonucleoprotein domain family, member 4B -0.00525701
IFITM3 interferon induced transmembrane protein 3 -0.00525492
SIX1 SIX homeobox 1 -0.0052494
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00523942
KRT15 keratin 15, type I -0.00523232
TNNC1 troponin C type 1 (slow) -0.00522591
HEATR1 HEAT repeat containing 1 -0.00522231
FBL fibrillarin -0.00521393
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.00521171
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00520706
ACKR3 atypical chemokine receptor 3 -0.00520677
ECM1 extracellular matrix protein 1 -0.00520206
PPIH peptidylprolyl isomerase H (cyclophilin H) -0.00520201
USP12P1 ubiquitin specific peptidase 12 pseudogene 1 -0.00519645
RAB15 RAB15, member RAS oncogene family -0.00518752
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.00516247
CAVIN2 caveolae associated protein 2 -0.00515201
HOPX HOP homeobox -0.00513988
BAG1 BCL2-associated athanogene -0.0051338
CYB5A cytochrome b5 type A (microsomal) -0.00512416
CRYM crystallin, mu -0.00511237
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -0.00511154
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00511059
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00510841
RFTN1 raftlin, lipid raft linker 1 -0.00509869
FAM107A family with sequence similarity 107, member A -0.00509437
RYR1 ryanodine receptor 1 (skeletal) -0.00509374
MT1HL1 metallothionein 1H-like 1 -0.00509115
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00507888
RNF141 ring finger protein 141 -0.00506713
FSTL1 follistatin-like 1 -0.00505995
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.00504238
MMP12 matrix metallopeptidase 12 -0.00504123
EGFL6 EGF-like-domain, multiple 6 -0.00503821
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.00503557
ERAP1 endoplasmic reticulum aminopeptidase 1 -0.00501727
ZDHHC13 zinc finger, DHHC-type containing 13 -0.00501528
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.00501428
ADAM23 ADAM metallopeptidase domain 23 -0.00500011
STATH statherin -0.00499057
EIF5A eukaryotic translation initiation factor 5A -0.00498317
PCCA propionyl CoA carboxylase, alpha polypeptide -0.00497828
PITX1 paired-like homeodomain 1 -0.00497422
CLINT1 clathrin interactor 1 -0.0049657
SPARCL1 SPARC-like 1 (hevin) -0.00496031
NOAZFP nucleolar atypical zinc finger -0.00495776
ARID5B AT rich interactive domain 5B (MRF1-like) -0.00495504
ENOPH1 enolase-phosphatase 1 -0.00495429
WNT5A wingless-type MMTV integration site family, member 5A -0.0049505
SPINT1 serine peptidase inhibitor, Kunitz type 1 -0.00494958
TBC1D2B TBC1 domain family, member 2B -0.00494782
WDR43 WD repeat domain 43 -0.0049457
ZNF750 zinc finger protein 750 -0.00494414
TSPYL5 TSPY-like 5 -0.00494198
H2AFJ H2A histone family, member J -0.0049282
RGS13 regulator of G-protein signaling 13 -0.00492203
DSG3 desmoglein 3 -0.00491776
CASP7 caspase 7, apoptosis-related cysteine peptidase -0.0049159
FGFR1 fibroblast growth factor receptor 1 -0.00491232
AKR1C3 aldo-keto reductase family 1, member C3 -0.00490687
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00488673
THBS4 thrombospondin 4 -0.00488382
ADCY3 adenylate cyclase 3 -0.00487878
DDAH2 dimethylarginine dimethylaminohydrolase 2 -0.00486378
LGI1 leucine-rich, glioma inactivated 1 -0.00486336
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -0.00486302
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00484849
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -0.00483399