CCNA1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description cyclin A1|The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8900)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CCNA1
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Genes

66 co-expressed genes for CCNA1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ACR acrosin
ACRV1 acrosomal vesicle protein 1
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACTL7A actin-like 7A
ACTL7B actin-like 7B
AKAP3 A kinase (PRKA) anchor protein 3
ANKRD7 ankyrin repeat domain 7
APH1B APH1B gamma secretase subunit
C9ORF9 chromosome 9 open reading frame 9
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC70 coiled-coil domain containing 70
CCIN calicin
CCNA1 cyclin A1
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CRISP2 cysteine-rich secretory protein 2
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25
DNALI1 dynein, axonemal, light intermediate chain 1
FSCN3 fascin actin-bundling protein 3, testicular
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GID4 GID complex subunit 4
GRK4 G protein-coupled receptor kinase 4
GSG1 germ cell associated 1
GSTM3 glutathione S-transferase mu 3 (brain)
HRASLS HRAS-like suppressor
HSPA1L heat shock 70kDa protein 1-like
IL13RA2 interleukin 13 receptor, alpha 2
IQCE IQ motif containing E
KCNK4 potassium channel, two pore domain subfamily K, member 4
KDM4D lysine (K)-specific demethylase 4D
LDHC lactate dehydrogenase C
LOC81691 exonuclease NEF-sp
MLF1 myeloid leukemia factor 1
MROH7 maestro heat-like repeat family member 7
MS4A5 membrane-spanning 4-domains, subfamily A, member 5
OAZ3 ornithine decarboxylase antizyme 3
ODF1 outer dense fiber of sperm tails 1
ODF2 outer dense fiber of sperm tails 2
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PGK2 phosphoglycerate kinase 2
PHF7 PHD finger protein 7
PIAS2 protein inhibitor of activated STAT, 2
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRM1 protamine 1
PRM2 protamine 2
RBMXL2 RNA binding motif protein, X-linked-like 2
RFPL3S RFPL3 antisense
RIBC2 RIB43A domain with coiled-coils 2
ROPN1 rhophilin associated tail protein 1
SLC6A16 solute carrier family 6, member 16
SOX5 SRY (sex determining region Y)-box 5
SPA17 sperm autoantigenic protein 17
SPAG6 sperm associated antigen 6
SPATA6 spermatogenesis associated 6
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TCP11 t-complex 11, testis-specific
TEX14 testis expressed 14
TKTL1 transketolase-like 1
TNP1 transition protein 1 (during histone to protamine replacement)
TPTE transmembrane phosphatase with tensin homology
TSSK2 testis-specific serine kinase 2
TUBA3C tubulin, alpha 3c
UBQLN3 ubiquilin 3
YBX2 Y box binding protein 2
ZC2HC1C zinc finger, C2HC-type containing 1C
ZMYND10 zinc finger, MYND-type containing 10
ZPBP zona pellucida binding protein