CCNA2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description cyclin A2|The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 890)
External Link https://ncbi.nlm.nih.gov/gene/890
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Genes

498 genes differentially expressed following the CCNA2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IFI27 interferon, alpha-inducible protein 27 0.0223208
IFI6 interferon, alpha-inducible protein 6 0.0151592
ISG15 ISG15 ubiquitin-like modifier 0.0150329
MX1 MX dynamin-like GTPase 1 0.0142931
MXRA5 matrix-remodelling associated 5 0.0138495
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0135654
RRAGD Ras-related GTP binding D 0.0134856
FBLN1 fibulin 1 0.0127712
GPNMB glycoprotein (transmembrane) nmb 0.0120655
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.0120258
IFI44L interferon-induced protein 44-like 0.0117701
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0115831
CCNE2 cyclin E2 0.0113706
XIC X chromosome inactivation center 0.0111955
C3 complement component 3 0.0110928
ASS1 argininosuccinate synthase 1 0.0110764
IFI44 interferon-induced protein 44 0.0110171
CXCL8 chemokine (C-X-C motif) ligand 8 0.010765
PLAAT3 phospholipase A and acyltransferase 3 0.0106609
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.0106426
SPINK1 serine peptidase inhibitor, Kazal type 1 0.0105393
SRPX sushi-repeat containing protein, X-linked 0.0104344
ADIRF adipogenesis regulatory factor 0.0103566
CSRP2 cysteine and glycine-rich protein 2 0.0101857
CFB complement factor B 0.0101793
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.0101667
SCPEP1 serine carboxypeptidase 1 0.0101153
MICB MHC class I polypeptide-related sequence B 0.0100232
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0100022
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00971934
PCLAF PCNA clamp associated factor 0.00971666
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00964013
LXN latexin 0.00951939
HSPB8 heat shock 22kDa protein 8 0.00949486
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00945188
GPR137B G protein-coupled receptor 137B 0.00942488
BST2 bone marrow stromal cell antigen 2 0.00941014
PDGFRL platelet-derived growth factor receptor-like 0.00940804
GNAS GNAS complex locus 0.00931515
HSPB11 heat shock protein family B (small), member 11 0.0092996
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00928685
S100A10 S100 calcium binding protein A10 0.00915398
COL14A1 collagen, type XIV, alpha 1 0.00912276
PARP12 poly (ADP-ribose) polymerase family, member 12 0.00911116
PLAT plasminogen activator, tissue 0.00908069
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00906137
NIBAN1 niban apoptosis regulator 1 0.00904543
PBLD phenazine biosynthesis-like protein domain containing 0.00885082
AKAP12 A kinase (PRKA) anchor protein 12 0.00881083
AMIGO2 adhesion molecule with Ig-like domain 2 0.00875069
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.0087254
PSCA prostate stem cell antigen 0.00867681
ASPN asporin 0.00866689
ECM1 extracellular matrix protein 1 0.00865417
FABP4 fatty acid binding protein 4, adipocyte 0.00863382
MFAP5 microfibrillar associated protein 5 0.00862004
EFHD1 EF-hand domain family, member D1 0.00861693
ANXA4 annexin A4 0.00859052
TST thiosulfate sulfurtransferase (rhodanese) 0.00850826
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00849197
GSTM3 glutathione S-transferase mu 3 (brain) 0.00847568
REG1A regenerating islet-derived 1 alpha 0.0084534
DCN decorin 0.00837079
COL4A1 collagen, type IV, alpha 1 0.00835141
AKR1C3 aldo-keto reductase family 1, member C3 0.0082877
COL5A2 collagen, type V, alpha 2 0.00826381
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00824111
MELK maternal embryonic leucine zipper kinase 0.00823834
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00822615
GPX1 glutathione peroxidase 1 0.00816232
DUSP5 dual specificity phosphatase 5 0.00810617
C8ORF4 chromosome 8 open reading frame 4 0.00810277
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.00807793
S100A8 S100 calcium binding protein A8 0.00807477
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00800834
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.00799125
TSPAN1 tetraspanin 1 0.00797295
TPD52 tumor protein D52 0.00796543
IRF7 interferon regulatory factor 7 0.00795637
ARHGAP29 Rho GTPase activating protein 29 0.00793813
APOD apolipoprotein D 0.00787096
AGTR1 angiotensin II receptor, type 1 0.00784805
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00782112
STC1 stanniocalcin 1 0.00781317
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00780888
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.00777612
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00777117
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.00775986
FN1 fibronectin 1 0.00773008
CLEC3B C-type lectin domain family 3, member B 0.00770022
APLP2 amyloid beta (A4) precursor-like protein 2 0.00769379
PRDX2 peroxiredoxin 2 0.00764647
FSTL1 follistatin-like 1 0.00761373
NXN nucleoredoxin 0.00760608
MYH10 myosin, heavy chain 10, non-muscle 0.00758081
XAF1 XIAP associated factor 1 0.00757235
FHL1 four and a half LIM domains 1 0.00756692
LGALS1 lectin, galactoside-binding, soluble, 1 0.0075626
WLS wntless Wnt ligand secretion mediator 0.00755535
DPYSL2 dihydropyrimidinase-like 2 0.00755475
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00754729
FXYD3 FXYD domain containing ion transport regulator 3 0.00751734
TGFA transforming growth factor, alpha 0.00744851
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00744075
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 0.00743723
CTSK cathepsin K 0.00740652
RSAD2 radical S-adenosyl methionine domain containing 2 0.00740296
ADGRF5 adhesion G protein-coupled receptor F5 0.0073599
SAMD4A sterile alpha motif domain containing 4A 0.00731937
PBX3 pre-B-cell leukemia homeobox 3 0.00730229
ITGAV integrin, alpha V 0.00716966
SPON2 spondin 2, extracellular matrix protein 0.00715834
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.00715744
TRIB2 tribbles pseudokinase 2 0.00714208
QPCT glutaminyl-peptide cyclotransferase 0.00712545
THBS2 thrombospondin 2 0.00711989
GPX3 glutathione peroxidase 3 0.00711157
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00711088
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 0.00710863
BLNK B-cell linker 0.00710258
MT1E metallothionein 1E 0.00706211
HLA-B major histocompatibility complex, class I, B 0.00706024
SCGB2A2 secretoglobin, family 2A, member 2 0.00704717
PPIF peptidylprolyl isomerase F 0.00703159
TSPO translocator protein (18kDa) 0.00700652
ABHD3 abhydrolase domain containing 3 0.00699176
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00697684
CD36 CD36 molecule (thrombospondin receptor) 0.00697097
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00696554
FAM111A family with sequence similarity 111, member A 0.00694072
COLEC12 collectin sub-family member 12 0.00693647
IFI16 interferon, gamma-inducible protein 16 0.00686468
GREM1 gremlin 1, DAN family BMP antagonist 0.0068605
IFITM1 interferon induced transmembrane protein 1 0.0068598
TACSTD2 tumor-associated calcium signal transducer 2 0.00685628
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00683795
ITGB4 integrin, beta 4 0.00682672
GOLM1 golgi membrane protein 1 0.00679975
SIK1 salt-inducible kinase 1 0.00678901
SP110 SP110 nuclear body protein 0.00676878
ZNF91 zinc finger protein 91 0.00674507
SGK1 serum/glucocorticoid regulated kinase 1 0.00674065
TUFT1 tuftelin 1 0.00672425
MME membrane metallo-endopeptidase 0.00671634
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00670721
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 0.0066979
PXDC1 PX domain containing 1 0.00668978
ANXA10 annexin A10 0.00668292
GLRX glutaredoxin (thioltransferase) 0.00666148
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00663335
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 0.00662763
MX2 MX dynamin-like GTPase 2 0.0066136
OPTN optineurin 0.00661069
CXCL14 chemokine (C-X-C motif) ligand 14 0.00660877
PLXNA1 plexin A1 0.0065766
CENPU centromere protein U 0.00657449
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00657321
GOLGA8H golgin A8 family, member H 0.00657148
IRF9 interferon regulatory factor 9 0.00654768
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.00654236
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.00650432
TJP2 tight junction protein 2 0.00650334
HLA-C major histocompatibility complex, class I, C 0.00649285
MAN1C1 mannosidase, alpha, class 1C, member 1 0.00649004
INAVA innate immunity activator 0.00646538
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00645335
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00644934
ZWINT ZW10 interacting kinetochore protein 0.00644298
GDF15 growth differentiation factor 15 0.00643798
ORC6 origin recognition complex, subunit 6 0.00643589
AOX1 aldehyde oxidase 1 0.00642907
MITF microphthalmia-associated transcription factor 0.00642103
RAB9A RAB9A, member RAS oncogene family 0.00639458
OSBPL2 oxysterol binding protein-like 2 0.00637933
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00635798
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00635424
TTC39A tetratricopeptide repeat domain 39A 0.00632734
TSPAN8 tetraspanin 8 0.00632028
SLC43A3 solute carrier family 43, member 3 0.00631058
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00630799
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.00626859
MGLL monoglyceride lipase 0.00625647
PLXNB2 plexin B2 0.00625147
SFRP4 secreted frizzled-related protein 4 0.00622467
TPST2 tyrosylprotein sulfotransferase 2 0.00621987
MDK midkine (neurite growth-promoting factor 2) 0.00620295
OGN osteoglycin 0.00619534
SMCO4 single-pass membrane protein with coiled-coil domains 4 0.00619505
PXMP2 peroxisomal membrane protein 2, 22kDa 0.00619364
DEFB1 defensin, beta 1 0.00618103
MT1X metallothionein 1X 0.00617736
HIP1R huntingtin interacting protein 1 related 0.00617588
RUNX1 runt-related transcription factor 1 0.0061711
NUP210 nucleoporin 210kDa 0.00616355
EGFL6 EGF-like-domain, multiple 6 0.00616303
BRCA1 breast cancer 1, early onset 0.00616183
CAPG capping protein (actin filament), gelsolin-like 0.0061595
G0S2 G0/G1 switch 2 0.00615819
CAV2 caveolin 2 0.00615516
SSPN sarcospan 0.00615122
CAV1 caveolin 1, caveolae protein, 22kDa 0.00613037
GRN granulin 0.00611815
FBLN2 fibulin 2 0.00611614
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.00611169
TM7SF2 transmembrane 7 superfamily member 2 0.00610437
CFD complement factor D (adipsin) 0.00609432
OASL 2'-5'-oligoadenylate synthetase-like 0.00609195
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00608334
MYO1B myosin IB 0.00607871
GSN gelsolin 0.00607673
OXCT1 3-oxoacid CoA transferase 1 0.00607399
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00606443
EIF5A eukaryotic translation initiation factor 5A 0.00605585
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00604606
VAMP8 vesicle-associated membrane protein 8 0.0060268
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00599221
CCNA2 cyclin A2 0.00599076
OSBPL3 oxysterol binding protein-like 3 0.00594907
SAMD9 sterile alpha motif domain containing 9 0.00592851
FHL2 four and a half LIM domains 2 0.00591434
RRM2 ribonucleotide reductase M2 0.00590648
PHYH phytanoyl-CoA 2-hydroxylase 0.00590633
HLA-F major histocompatibility complex, class I, F 0.00589752
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00589656
C1ORF115 chromosome 1 open reading frame 115 0.00589643
ZNF93 zinc finger protein 93 0.00589397
CDC25A cell division cycle 25A 0.00589358
FNBP1L formin binding protein 1-like 0.00589047
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.00587398
MXRA7 matrix-remodelling associated 7 0.00587025
THY1 Thy-1 cell surface antigen 0.00586222
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00585346
CYBA cytochrome b-245, alpha polypeptide 0.00585256
LHFP lipoma HMGIC fusion partner 0.00584658
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.00582824
KRT8 keratin 8, type II 0.00582742
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.0058236
SLC35E3 solute carrier family 35, member E3 0.00582302
SPINT1 serine peptidase inhibitor, Kunitz type 1 0.00582012
VCL vinculin 0.00580038
ADCY9 adenylate cyclase 9 0.00579366
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00577362
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00577166
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.00576423
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.005762
SGCE sarcoglycan, epsilon 0.00575815
EMP1 epithelial membrane protein 1 0.00575567
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00575077
MMP7 matrix metallopeptidase 7 0.00574719
AGR2 anterior gradient 2 0.00574489

decreased expression

Symbol Name Standardized Value
KIF20A kinesin family member 20A -0.0196221
PLK1 polo-like kinase 1 -0.0158809
CDC20 cell division cycle 20 -0.0130597
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.0126544
RAD23B RAD23 homolog B (S. cerevisiae) -0.0122059
MAGEA3 melanoma antigen family A3 -0.012086
DEPDC1 DEP domain containing 1 -0.0120759
UBE2S ubiquitin-conjugating enzyme E2S -0.0108925
ODC1 ornithine decarboxylase 1 -0.0105406
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.010081
PSRC1 proline/serine-rich coiled-coil 1 -0.00966989
MAGEA12 melanoma antigen family A12 -0.00955111
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.00954411
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00934955
CENPE centromere protein E, 312kDa -0.00918703
NEK2 NIMA-related kinase 2 -0.00909127
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -0.0090763
CDCA3 cell division cycle associated 3 -0.00888511
HMMR hyaluronan-mediated motility receptor (RHAMM) -0.00883241
EREG epiregulin -0.00857419
PBK PDZ binding kinase -0.00839719
PRMT1 protein arginine methyltransferase 1 -0.00838326
NPM3 nucleophosmin/nucleoplasmin 3 -0.00833445
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00804379
WNT5A wingless-type MMTV integration site family, member 5A -0.00798047
KIF18A kinesin family member 18A -0.00795915
AURKA aurora kinase A -0.00790972
BCLAF1 BCL2-associated transcription factor 1 -0.00785898
S100A12 S100 calcium binding protein A12 -0.00779568
MRPL58 mitochondrial ribosomal protein L58 -0.00774158
CDKN3 cyclin-dependent kinase inhibitor 3 -0.00771926
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.0077078
AUTS2 autism susceptibility candidate 2 -0.00768205
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00761366
BIRC5 baculoviral IAP repeat containing 5 -0.00757417
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.00756511
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00739298
NELL2 NEL-like 2 (chicken) -0.00729776
CENPF centromere protein F, 350/400kDa -0.00720753
LMNB1 lamin B1 -0.00719358
MED28 mediator complex subunit 28 -0.00717598
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00710899
E2F5 E2F transcription factor 5, p130-binding -0.00710043
SPC25 SPC25, NDC80 kinetochore complex component -0.00708892
PPID peptidylprolyl isomerase D -0.00702497
PRAME preferentially expressed antigen in melanoma -0.00699113
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -0.00698507
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00692087
TPX2 TPX2, microtubule-associated -0.00686997
PARPBP PARP1 binding protein -0.00685356
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -0.00683917
SRP72 signal recognition particle 72kDa -0.00683406
DBF4 DBF4 zinc finger -0.00682192
CDCA8 cell division cycle associated 8 -0.00680285
RBMX RNA binding motif protein, X-linked -0.00678935
NDC80 NDC80 kinetochore complex component -0.00677834
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00677203
MMP12 matrix metallopeptidase 12 -0.00671247
CDC42 cell division cycle 42 -0.00670522
HMBS hydroxymethylbilane synthase -0.00666566
GAL galanin/GMAP prepropeptide -0.00661267
GEMIN2 gem (nuclear organelle) associated protein 2 -0.00658253
OLFM1 olfactomedin 1 -0.00656549
PRPF19 pre-mRNA processing factor 19 -0.00654489
COPS4 COP9 signalosome subunit 4 -0.00652911
ESR1 estrogen receptor 1 -0.00651243
KIF4A kinesin family member 4A -0.00646562
BCHE butyrylcholinesterase -0.00646523
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00646412
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -0.00643804
AP1AR adaptor-related protein complex 1 associated regulatory protein -0.00641512
DLK1 delta-like 1 homolog (Drosophila) -0.00641187
CENPA centromere protein A -0.00638387
RPS5 ribosomal protein S5 -0.00638255
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.00636061
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00627152
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) -0.00626975
OIP5 Opa interacting protein 5 -0.00623087
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00621612
TTK TTK protein kinase -0.0061943
FUS FUS RNA binding protein -0.00613327
EXOSC9 exosome component 9 -0.00613099
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -0.00610786
ATG5 autophagy related 5 -0.00610071
MAGEA1 melanoma antigen family A1 -0.00609169
CCR7 chemokine (C-C motif) receptor 7 -0.00608983
KDM5D lysine (K)-specific demethylase 5D -0.00607374
FABP7 fatty acid binding protein 7, brain -0.00605997
CEMIP cell migration inducing protein, hyaluronan binding -0.00605731
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -0.00604727
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00600953
CDC25C cell division cycle 25C -0.00599907
NUP37 nucleoporin 37kDa -0.00599253
DSC2 desmocollin 2 -0.00597616
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.00596337
MRPS30 mitochondrial ribosomal protein S30 -0.00595205
NOX1 NADPH oxidase 1 -0.005952
KIF14 kinesin family member 14 -0.00595134
GPR88 G protein-coupled receptor 88 -0.00592015
PDAP1 PDGFA associated protein 1 -0.00591697
MAP2K6 mitogen-activated protein kinase kinase 6 -0.00590131
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -0.0058833
EXOC5 exocyst complex component 5 -0.00586365
SRSF1 serine/arginine-rich splicing factor 1 -0.00585426
CIRBP cold inducible RNA binding protein -0.00584963
PHB2 prohibitin 2 -0.0058224
CNGB1 cyclic nucleotide gated channel beta 1 -0.005816
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -0.00580883
FBL fibrillarin -0.0058047
INTS12 integrator complex subunit 12 -0.00579059
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -0.00578945
ISOC2 isochorismatase domain containing 2 -0.00578859
PTTG1 pituitary tumor-transforming 1 -0.00578543
XCL1 chemokine (C motif) ligand 1 -0.00578011
SET SET nuclear proto-oncogene -0.00577009
TRIM28 tripartite motif containing 28 -0.00574313
COMMD10 COMM domain containing 10 -0.00573974
SFPQ splicing factor proline/glutamine-rich -0.00572501
HMGB2 high mobility group box 2 -0.00572164
FKBP10 FK506 binding protein 10, 65 kDa -0.00569375
NDC1 NDC1 transmembrane nucleoporin -0.00569158
ZNF750 zinc finger protein 750 -0.00568398
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00567956
GYPA glycophorin A (MNS blood group) -0.0056367
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00562394
PITX2 paired-like homeodomain 2 -0.00557035
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa -0.00554491
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 -0.0055225
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.00548773
EIF4E eukaryotic translation initiation factor 4E -0.00548346
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -0.00547274
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -0.00545346
KIF1B kinesin family member 1B -0.00544838
ARL4A ADP-ribosylation factor-like 4A -0.00544816
CCNB2 cyclin B2 -0.00544627
FOXG1 forkhead box G1 -0.00544254
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00543715
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.00543414
SSX1 synovial sarcoma, X breakpoint 1 -0.00543149
YME1L1 YME1-like 1 ATPase -0.00539236
SATB2 SATB homeobox 2 -0.00538252
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00537136
CDA cytidine deaminase -0.00536821
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00535508
PRR16 proline rich 16 -0.00534711
SINHCAF SIN3-HDAC complex associated factor -0.00534189
ELL2 elongation factor, RNA polymerase II, 2 -0.0053289
SKA1 spindle and kinetochore associated complex subunit 1 -0.0053167
RAD23A RAD23 homolog A (S. cerevisiae) -0.00531069
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00529916
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00528689
CD1E CD1e molecule -0.00527917
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.00524969
GTF2I general transcription factor IIi -0.00523991
GPHN gephyrin -0.00523864
MNDA myeloid cell nuclear differentiation antigen -0.00523849
CEP55 centrosomal protein 55kDa -0.00523226
MAGEA4 melanoma antigen family A4 -0.00522001
NECTIN3 nectin cell adhesion molecule 3 -0.00521495
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -0.00520939
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 -0.00519917
ANKRD10 ankyrin repeat domain 10 -0.00518218
CD200 CD200 molecule -0.00517955
NREP neuronal regeneration related protein -0.00516977
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.00515767
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma -0.00515684
SI sucrase-isomaltase (alpha-glucosidase) -0.00514903
WDR12 WD repeat domain 12 -0.00514795
CLCA1 chloride channel accessory 1 -0.00514648
MRPL12 mitochondrial ribosomal protein L12 -0.0051433
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -0.00513035
SEPHS1 selenophosphate synthetase 1 -0.00512044
PUF60 poly-U binding splicing factor 60KDa -0.00511767
FAM86B1 family with sequence similarity 86, member B1 -0.00511395
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -0.00509844
L1TD1 LINE-1 type transposase domain containing 1 -0.00509574
LARP7 La ribonucleoprotein domain family, member 7 -0.00508784
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00508424
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -0.00507824
ARMCX2 armadillo repeat containing, X-linked 2 -0.00506024
IFRD2 interferon-related developmental regulator 2 -0.00503161
GAP43 growth associated protein 43 -0.00500647
HMGB1 high mobility group box 1 -0.00500237
MKI67 marker of proliferation Ki-67 -0.00499913
ARHGAP11A Rho GTPase activating protein 11A -0.00499418
FOCAD focadhesin -0.00499124
MAGEB2 melanoma antigen family B2 -0.00497301
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00496163
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase -0.00495529
CDC123 cell division cycle 123 -0.00495257
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -0.00495121
ANO1 anoctamin 1, calcium activated chloride channel -0.00494318
PLCB4 phospholipase C, beta 4 -0.00494179
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.00494071
MRPL3 mitochondrial ribosomal protein L3 -0.00494
CHTOP chromatin target of PRMT1 -0.00493254
ILF2 interleukin enhancer binding factor 2 -0.00493093
EPAS1 endothelial PAS domain protein 1 -0.00492591
TACC3 transforming, acidic coiled-coil containing protein 3 -0.00492264
PTTG3P pituitary tumor-transforming 3, pseudogene -0.00491826
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 -0.00490821
GDI2 GDP dissociation inhibitor 2 -0.00490732
ANAPC10 anaphase promoting complex subunit 10 -0.00489208
BORA bora, aurora kinase A activator -0.00488378
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.00486423
CASC3 cancer susceptibility candidate 3 -0.00486289
RIOX2 ribosomal oxygenase 2 -0.00486083
TBL1X transducin (beta)-like 1X-linked -0.00485922
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -0.00484595
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.00484386
OXSM 3-oxoacyl-ACP synthase, mitochondrial -0.00484371
TPTE transmembrane phosphatase with tensin homology -0.00484112
FABP6 fatty acid binding protein 6, ileal -0.0048033
KIF23 kinesin family member 23 -0.00480182
GPN1 GPN-loop GTPase 1 -0.00479925
MATR3 matrin 3 -0.00477374
TFB2M transcription factor B2, mitochondrial -0.00474664
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -0.00474539
ODAM odontogenic, ameloblast asssociated -0.00474092
CLCN3 chloride channel, voltage-sensitive 3 -0.0047391
KAT8 K(lysine) acetyltransferase 8 -0.00473806
UFSP2 UFM1-specific peptidase 2 -0.00473319
BRD8 bromodomain containing 8 -0.00472865
PNO1 partner of NOB1 homolog (S. cerevisiae) -0.00470954
SEC24D SEC24 family member D -0.00470552
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00470254
FZD3 frizzled class receptor 3 -0.004699
C5ORF28 chromosome 5 open reading frame 28 -0.00469891
CAPRIN1 cell cycle associated protein 1 -0.00469325
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00469295
CCDC59 coiled-coil domain containing 59 -0.00468897
SCRG1 stimulator of chondrogenesis 1 -0.00468489
AQP4 aquaporin 4 -0.00468091
ILK integrin-linked kinase -0.004678
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00467583
LIG3 ligase III, DNA, ATP-dependent -0.00467311
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 -0.00466551
TRA2B transformer 2 beta homolog (Drosophila) -0.00466386
MAPKAPK5-AS1 MAPKAPK5 antisense RNA 1 -0.0046578
PBX1 pre-B-cell leukemia homeobox 1 -0.00465382
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -0.0046437
WDR74 WD repeat domain 74 -0.00462873
SLAMF7 SLAM family member 7 -0.00462486
SRSF3 serine/arginine-rich splicing factor 3 -0.00462452
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.0046218
RSL1D1 ribosomal L1 domain containing 1 -0.00461314
PIMREG PICALM interacting mitotic regulator -0.00460989
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.00460605