| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cyclin A2|The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 890) |
| External Link | https://ncbi.nlm.nih.gov/gene/890 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the CCNA2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | 0.0223208 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0151592 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0150329 |
| MX1 | MX dynamin-like GTPase 1 | 0.0142931 |
| MXRA5 | matrix-remodelling associated 5 | 0.0138495 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0135654 |
| RRAGD | Ras-related GTP binding D | 0.0134856 |
| FBLN1 | fibulin 1 | 0.0127712 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.0120655 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0120258 |
| IFI44L | interferon-induced protein 44-like | 0.0117701 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0115831 |
| CCNE2 | cyclin E2 | 0.0113706 |
| XIC | X chromosome inactivation center | 0.0111955 |
| C3 | complement component 3 | 0.0110928 |
| ASS1 | argininosuccinate synthase 1 | 0.0110764 |
| IFI44 | interferon-induced protein 44 | 0.0110171 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.010765 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0106609 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0106426 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.0105393 |
| SRPX | sushi-repeat containing protein, X-linked | 0.0104344 |
| ADIRF | adipogenesis regulatory factor | 0.0103566 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.0101857 |
| CFB | complement factor B | 0.0101793 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.0101667 |
| SCPEP1 | serine carboxypeptidase 1 | 0.0101153 |
| MICB | MHC class I polypeptide-related sequence B | 0.0100232 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0100022 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00971934 |
| PCLAF | PCNA clamp associated factor | 0.00971666 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00964013 |
| LXN | latexin | 0.00951939 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00949486 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00945188 |
| GPR137B | G protein-coupled receptor 137B | 0.00942488 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00941014 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00940804 |
| GNAS | GNAS complex locus | 0.00931515 |
| HSPB11 | heat shock protein family B (small), member 11 | 0.0092996 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00928685 |
| S100A10 | S100 calcium binding protein A10 | 0.00915398 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00912276 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00911116 |
| PLAT | plasminogen activator, tissue | 0.00908069 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00906137 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00904543 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.00885082 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00881083 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00875069 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.0087254 |
| PSCA | prostate stem cell antigen | 0.00867681 |
| ASPN | asporin | 0.00866689 |
| ECM1 | extracellular matrix protein 1 | 0.00865417 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00863382 |
| MFAP5 | microfibrillar associated protein 5 | 0.00862004 |
| EFHD1 | EF-hand domain family, member D1 | 0.00861693 |
| ANXA4 | annexin A4 | 0.00859052 |
| TST | thiosulfate sulfurtransferase (rhodanese) | 0.00850826 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00849197 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00847568 |
| REG1A | regenerating islet-derived 1 alpha | 0.0084534 |
| DCN | decorin | 0.00837079 |
| COL4A1 | collagen, type IV, alpha 1 | 0.00835141 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.0082877 |
| COL5A2 | collagen, type V, alpha 2 | 0.00826381 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00824111 |
| MELK | maternal embryonic leucine zipper kinase | 0.00823834 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00822615 |
| GPX1 | glutathione peroxidase 1 | 0.00816232 |
| DUSP5 | dual specificity phosphatase 5 | 0.00810617 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00810277 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.00807793 |
| S100A8 | S100 calcium binding protein A8 | 0.00807477 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00800834 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.00799125 |
| TSPAN1 | tetraspanin 1 | 0.00797295 |
| TPD52 | tumor protein D52 | 0.00796543 |
| IRF7 | interferon regulatory factor 7 | 0.00795637 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00793813 |
| APOD | apolipoprotein D | 0.00787096 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00784805 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00782112 |
| STC1 | stanniocalcin 1 | 0.00781317 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00780888 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00777612 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00777117 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00775986 |
| FN1 | fibronectin 1 | 0.00773008 |
| CLEC3B | C-type lectin domain family 3, member B | 0.00770022 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00769379 |
| PRDX2 | peroxiredoxin 2 | 0.00764647 |
| FSTL1 | follistatin-like 1 | 0.00761373 |
| NXN | nucleoredoxin | 0.00760608 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00758081 |
| XAF1 | XIAP associated factor 1 | 0.00757235 |
| FHL1 | four and a half LIM domains 1 | 0.00756692 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0075626 |
| WLS | wntless Wnt ligand secretion mediator | 0.00755535 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00755475 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.00754729 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00751734 |
| TGFA | transforming growth factor, alpha | 0.00744851 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00744075 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.00743723 |
| CTSK | cathepsin K | 0.00740652 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00740296 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.0073599 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00731937 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00730229 |
| ITGAV | integrin, alpha V | 0.00716966 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00715834 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00715744 |
| TRIB2 | tribbles pseudokinase 2 | 0.00714208 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00712545 |
| THBS2 | thrombospondin 2 | 0.00711989 |
| GPX3 | glutathione peroxidase 3 | 0.00711157 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00711088 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.00710863 |
| BLNK | B-cell linker | 0.00710258 |
| MT1E | metallothionein 1E | 0.00706211 |
| HLA-B | major histocompatibility complex, class I, B | 0.00706024 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00704717 |
| PPIF | peptidylprolyl isomerase F | 0.00703159 |
| TSPO | translocator protein (18kDa) | 0.00700652 |
| ABHD3 | abhydrolase domain containing 3 | 0.00699176 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00697684 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00697097 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00696554 |
| FAM111A | family with sequence similarity 111, member A | 0.00694072 |
| COLEC12 | collectin sub-family member 12 | 0.00693647 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00686468 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0068605 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0068598 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00685628 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00683795 |
| ITGB4 | integrin, beta 4 | 0.00682672 |
| GOLM1 | golgi membrane protein 1 | 0.00679975 |
| SIK1 | salt-inducible kinase 1 | 0.00678901 |
| SP110 | SP110 nuclear body protein | 0.00676878 |
| ZNF91 | zinc finger protein 91 | 0.00674507 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00674065 |
| TUFT1 | tuftelin 1 | 0.00672425 |
| MME | membrane metallo-endopeptidase | 0.00671634 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00670721 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.0066979 |
| PXDC1 | PX domain containing 1 | 0.00668978 |
| ANXA10 | annexin A10 | 0.00668292 |
| GLRX | glutaredoxin (thioltransferase) | 0.00666148 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00663335 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | 0.00662763 |
| MX2 | MX dynamin-like GTPase 2 | 0.0066136 |
| OPTN | optineurin | 0.00661069 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00660877 |
| PLXNA1 | plexin A1 | 0.0065766 |
| CENPU | centromere protein U | 0.00657449 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00657321 |
| GOLGA8H | golgin A8 family, member H | 0.00657148 |
| IRF9 | interferon regulatory factor 9 | 0.00654768 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00654236 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00650432 |
| TJP2 | tight junction protein 2 | 0.00650334 |
| HLA-C | major histocompatibility complex, class I, C | 0.00649285 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.00649004 |
| INAVA | innate immunity activator | 0.00646538 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00645335 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00644934 |
| ZWINT | ZW10 interacting kinetochore protein | 0.00644298 |
| GDF15 | growth differentiation factor 15 | 0.00643798 |
| ORC6 | origin recognition complex, subunit 6 | 0.00643589 |
| AOX1 | aldehyde oxidase 1 | 0.00642907 |
| MITF | microphthalmia-associated transcription factor | 0.00642103 |
| RAB9A | RAB9A, member RAS oncogene family | 0.00639458 |
| OSBPL2 | oxysterol binding protein-like 2 | 0.00637933 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00635798 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00635424 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00632734 |
| TSPAN8 | tetraspanin 8 | 0.00632028 |
| SLC43A3 | solute carrier family 43, member 3 | 0.00631058 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00630799 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 0.00626859 |
| MGLL | monoglyceride lipase | 0.00625647 |
| PLXNB2 | plexin B2 | 0.00625147 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00622467 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.00621987 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00620295 |
| OGN | osteoglycin | 0.00619534 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | 0.00619505 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00619364 |
| DEFB1 | defensin, beta 1 | 0.00618103 |
| MT1X | metallothionein 1X | 0.00617736 |
| HIP1R | huntingtin interacting protein 1 related | 0.00617588 |
| RUNX1 | runt-related transcription factor 1 | 0.0061711 |
| NUP210 | nucleoporin 210kDa | 0.00616355 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00616303 |
| BRCA1 | breast cancer 1, early onset | 0.00616183 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.0061595 |
| G0S2 | G0/G1 switch 2 | 0.00615819 |
| CAV2 | caveolin 2 | 0.00615516 |
| SSPN | sarcospan | 0.00615122 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00613037 |
| GRN | granulin | 0.00611815 |
| FBLN2 | fibulin 2 | 0.00611614 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00611169 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.00610437 |
| CFD | complement factor D (adipsin) | 0.00609432 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00609195 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00608334 |
| MYO1B | myosin IB | 0.00607871 |
| GSN | gelsolin | 0.00607673 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 0.00607399 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00606443 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00605585 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00604606 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.0060268 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00599221 |
| CCNA2 | cyclin A2 | 0.00599076 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.00594907 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00592851 |
| FHL2 | four and a half LIM domains 2 | 0.00591434 |
| RRM2 | ribonucleotide reductase M2 | 0.00590648 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00590633 |
| HLA-F | major histocompatibility complex, class I, F | 0.00589752 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00589656 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00589643 |
| ZNF93 | zinc finger protein 93 | 0.00589397 |
| CDC25A | cell division cycle 25A | 0.00589358 |
| FNBP1L | formin binding protein 1-like | 0.00589047 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 0.00587398 |
| MXRA7 | matrix-remodelling associated 7 | 0.00587025 |
| THY1 | Thy-1 cell surface antigen | 0.00586222 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00585346 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00585256 |
| LHFP | lipoma HMGIC fusion partner | 0.00584658 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.00582824 |
| KRT8 | keratin 8, type II | 0.00582742 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0058236 |
| SLC35E3 | solute carrier family 35, member E3 | 0.00582302 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.00582012 |
| VCL | vinculin | 0.00580038 |
| ADCY9 | adenylate cyclase 9 | 0.00579366 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00577362 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.00577166 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.00576423 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.005762 |
| SGCE | sarcoglycan, epsilon | 0.00575815 |
| EMP1 | epithelial membrane protein 1 | 0.00575567 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00575077 |
| MMP7 | matrix metallopeptidase 7 | 0.00574719 |
| AGR2 | anterior gradient 2 | 0.00574489 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KIF20A | kinesin family member 20A | -0.0196221 |
| PLK1 | polo-like kinase 1 | -0.0158809 |
| CDC20 | cell division cycle 20 | -0.0130597 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0126544 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0122059 |
| MAGEA3 | melanoma antigen family A3 | -0.012086 |
| DEPDC1 | DEP domain containing 1 | -0.0120759 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -0.0108925 |
| ODC1 | ornithine decarboxylase 1 | -0.0105406 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.010081 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00966989 |
| MAGEA12 | melanoma antigen family A12 | -0.00955111 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.00954411 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00934955 |
| CENPE | centromere protein E, 312kDa | -0.00918703 |
| NEK2 | NIMA-related kinase 2 | -0.00909127 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0090763 |
| CDCA3 | cell division cycle associated 3 | -0.00888511 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.00883241 |
| EREG | epiregulin | -0.00857419 |
| PBK | PDZ binding kinase | -0.00839719 |
| PRMT1 | protein arginine methyltransferase 1 | -0.00838326 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00833445 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00804379 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00798047 |
| KIF18A | kinesin family member 18A | -0.00795915 |
| AURKA | aurora kinase A | -0.00790972 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.00785898 |
| S100A12 | S100 calcium binding protein A12 | -0.00779568 |
| MRPL58 | mitochondrial ribosomal protein L58 | -0.00774158 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -0.00771926 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.0077078 |
| AUTS2 | autism susceptibility candidate 2 | -0.00768205 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00761366 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00757417 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.00756511 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00739298 |
| NELL2 | NEL-like 2 (chicken) | -0.00729776 |
| CENPF | centromere protein F, 350/400kDa | -0.00720753 |
| LMNB1 | lamin B1 | -0.00719358 |
| MED28 | mediator complex subunit 28 | -0.00717598 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00710899 |
| E2F5 | E2F transcription factor 5, p130-binding | -0.00710043 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00708892 |
| PPID | peptidylprolyl isomerase D | -0.00702497 |
| PRAME | preferentially expressed antigen in melanoma | -0.00699113 |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 | -0.00698507 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00692087 |
| TPX2 | TPX2, microtubule-associated | -0.00686997 |
| PARPBP | PARP1 binding protein | -0.00685356 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00683917 |
| SRP72 | signal recognition particle 72kDa | -0.00683406 |
| DBF4 | DBF4 zinc finger | -0.00682192 |
| CDCA8 | cell division cycle associated 8 | -0.00680285 |
| RBMX | RNA binding motif protein, X-linked | -0.00678935 |
| NDC80 | NDC80 kinetochore complex component | -0.00677834 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00677203 |
| MMP12 | matrix metallopeptidase 12 | -0.00671247 |
| CDC42 | cell division cycle 42 | -0.00670522 |
| HMBS | hydroxymethylbilane synthase | -0.00666566 |
| GAL | galanin/GMAP prepropeptide | -0.00661267 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | -0.00658253 |
| OLFM1 | olfactomedin 1 | -0.00656549 |
| PRPF19 | pre-mRNA processing factor 19 | -0.00654489 |
| COPS4 | COP9 signalosome subunit 4 | -0.00652911 |
| ESR1 | estrogen receptor 1 | -0.00651243 |
| KIF4A | kinesin family member 4A | -0.00646562 |
| BCHE | butyrylcholinesterase | -0.00646523 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00646412 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | -0.00643804 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | -0.00641512 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00641187 |
| CENPA | centromere protein A | -0.00638387 |
| RPS5 | ribosomal protein S5 | -0.00638255 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.00636061 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00627152 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | -0.00626975 |
| OIP5 | Opa interacting protein 5 | -0.00623087 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00621612 |
| TTK | TTK protein kinase | -0.0061943 |
| FUS | FUS RNA binding protein | -0.00613327 |
| EXOSC9 | exosome component 9 | -0.00613099 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | -0.00610786 |
| ATG5 | autophagy related 5 | -0.00610071 |
| MAGEA1 | melanoma antigen family A1 | -0.00609169 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00608983 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00607374 |
| FABP7 | fatty acid binding protein 7, brain | -0.00605997 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00605731 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | -0.00604727 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00600953 |
| CDC25C | cell division cycle 25C | -0.00599907 |
| NUP37 | nucleoporin 37kDa | -0.00599253 |
| DSC2 | desmocollin 2 | -0.00597616 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00596337 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.00595205 |
| NOX1 | NADPH oxidase 1 | -0.005952 |
| KIF14 | kinesin family member 14 | -0.00595134 |
| GPR88 | G protein-coupled receptor 88 | -0.00592015 |
| PDAP1 | PDGFA associated protein 1 | -0.00591697 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00590131 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0058833 |
| EXOC5 | exocyst complex component 5 | -0.00586365 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00585426 |
| CIRBP | cold inducible RNA binding protein | -0.00584963 |
| PHB2 | prohibitin 2 | -0.0058224 |
| CNGB1 | cyclic nucleotide gated channel beta 1 | -0.005816 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.00580883 |
| FBL | fibrillarin | -0.0058047 |
| INTS12 | integrator complex subunit 12 | -0.00579059 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | -0.00578945 |
| ISOC2 | isochorismatase domain containing 2 | -0.00578859 |
| PTTG1 | pituitary tumor-transforming 1 | -0.00578543 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00578011 |
| SET | SET nuclear proto-oncogene | -0.00577009 |
| TRIM28 | tripartite motif containing 28 | -0.00574313 |
| COMMD10 | COMM domain containing 10 | -0.00573974 |
| SFPQ | splicing factor proline/glutamine-rich | -0.00572501 |
| HMGB2 | high mobility group box 2 | -0.00572164 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.00569375 |
| NDC1 | NDC1 transmembrane nucleoporin | -0.00569158 |
| ZNF750 | zinc finger protein 750 | -0.00568398 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00567956 |
| GYPA | glycophorin A (MNS blood group) | -0.0056367 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00562394 |
| PITX2 | paired-like homeodomain 2 | -0.00557035 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa | -0.00554491 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | -0.0055225 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00548773 |
| EIF4E | eukaryotic translation initiation factor 4E | -0.00548346 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 | -0.00547274 |
| COQ2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase | -0.00545346 |
| KIF1B | kinesin family member 1B | -0.00544838 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00544816 |
| CCNB2 | cyclin B2 | -0.00544627 |
| FOXG1 | forkhead box G1 | -0.00544254 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00543715 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.00543414 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00543149 |
| YME1L1 | YME1-like 1 ATPase | -0.00539236 |
| SATB2 | SATB homeobox 2 | -0.00538252 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00537136 |
| CDA | cytidine deaminase | -0.00536821 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00535508 |
| PRR16 | proline rich 16 | -0.00534711 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.00534189 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0053289 |
| SKA1 | spindle and kinetochore associated complex subunit 1 | -0.0053167 |
| RAD23A | RAD23 homolog A (S. cerevisiae) | -0.00531069 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00529916 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00528689 |
| CD1E | CD1e molecule | -0.00527917 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.00524969 |
| GTF2I | general transcription factor IIi | -0.00523991 |
| GPHN | gephyrin | -0.00523864 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00523849 |
| CEP55 | centrosomal protein 55kDa | -0.00523226 |
| MAGEA4 | melanoma antigen family A4 | -0.00522001 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.00521495 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) | -0.00520939 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | -0.00519917 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00518218 |
| CD200 | CD200 molecule | -0.00517955 |
| NREP | neuronal regeneration related protein | -0.00516977 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00515767 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma | -0.00515684 |
| SI | sucrase-isomaltase (alpha-glucosidase) | -0.00514903 |
| WDR12 | WD repeat domain 12 | -0.00514795 |
| CLCA1 | chloride channel accessory 1 | -0.00514648 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.0051433 |
| RRP15 | ribosomal RNA processing 15 homolog (S. cerevisiae) | -0.00513035 |
| SEPHS1 | selenophosphate synthetase 1 | -0.00512044 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00511767 |
| FAM86B1 | family with sequence similarity 86, member B1 | -0.00511395 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -0.00509844 |
| L1TD1 | LINE-1 type transposase domain containing 1 | -0.00509574 |
| LARP7 | La ribonucleoprotein domain family, member 7 | -0.00508784 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00508424 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.00507824 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00506024 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00503161 |
| GAP43 | growth associated protein 43 | -0.00500647 |
| HMGB1 | high mobility group box 1 | -0.00500237 |
| MKI67 | marker of proliferation Ki-67 | -0.00499913 |
| ARHGAP11A | Rho GTPase activating protein 11A | -0.00499418 |
| FOCAD | focadhesin | -0.00499124 |
| MAGEB2 | melanoma antigen family B2 | -0.00497301 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00496163 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | -0.00495529 |
| CDC123 | cell division cycle 123 | -0.00495257 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00495121 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00494318 |
| PLCB4 | phospholipase C, beta 4 | -0.00494179 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | -0.00494071 |
| MRPL3 | mitochondrial ribosomal protein L3 | -0.00494 |
| CHTOP | chromatin target of PRMT1 | -0.00493254 |
| ILF2 | interleukin enhancer binding factor 2 | -0.00493093 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00492591 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -0.00492264 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene | -0.00491826 |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 | -0.00490821 |
| GDI2 | GDP dissociation inhibitor 2 | -0.00490732 |
| ANAPC10 | anaphase promoting complex subunit 10 | -0.00489208 |
| BORA | bora, aurora kinase A activator | -0.00488378 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00486423 |
| CASC3 | cancer susceptibility candidate 3 | -0.00486289 |
| RIOX2 | ribosomal oxygenase 2 | -0.00486083 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00485922 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) | -0.00484595 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.00484386 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial | -0.00484371 |
| TPTE | transmembrane phosphatase with tensin homology | -0.00484112 |
| FABP6 | fatty acid binding protein 6, ileal | -0.0048033 |
| KIF23 | kinesin family member 23 | -0.00480182 |
| GPN1 | GPN-loop GTPase 1 | -0.00479925 |
| MATR3 | matrin 3 | -0.00477374 |
| TFB2M | transcription factor B2, mitochondrial | -0.00474664 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.00474539 |
| ODAM | odontogenic, ameloblast asssociated | -0.00474092 |
| CLCN3 | chloride channel, voltage-sensitive 3 | -0.0047391 |
| KAT8 | K(lysine) acetyltransferase 8 | -0.00473806 |
| UFSP2 | UFM1-specific peptidase 2 | -0.00473319 |
| BRD8 | bromodomain containing 8 | -0.00472865 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) | -0.00470954 |
| SEC24D | SEC24 family member D | -0.00470552 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00470254 |
| FZD3 | frizzled class receptor 3 | -0.004699 |
| C5ORF28 | chromosome 5 open reading frame 28 | -0.00469891 |
| CAPRIN1 | cell cycle associated protein 1 | -0.00469325 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00469295 |
| CCDC59 | coiled-coil domain containing 59 | -0.00468897 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00468489 |
| AQP4 | aquaporin 4 | -0.00468091 |
| ILK | integrin-linked kinase | -0.004678 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00467583 |
| LIG3 | ligase III, DNA, ATP-dependent | -0.00467311 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 | -0.00466551 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.00466386 |
| MAPKAPK5-AS1 | MAPKAPK5 antisense RNA 1 | -0.0046578 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00465382 |
| DARS2 | aspartyl-tRNA synthetase 2, mitochondrial | -0.0046437 |
| WDR74 | WD repeat domain 74 | -0.00462873 |
| SLAMF7 | SLAM family member 7 | -0.00462486 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.00462452 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0046218 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00461314 |
| PIMREG | PICALM interacting mitotic regulator | -0.00460989 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00460605 |