CCNA2 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description cyclin A2|The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 890)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CCNA2
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Genes

68 co-expressed genes for CCNA2 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ASF1B anti-silencing function 1B histone chaperone
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AURKA aurora kinase A
AURKB aurora kinase B
BIRC5 baculoviral IAP repeat containing 5
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CCNA2 cyclin A2
CCNB2 cyclin B2
CDC20 cell division cycle 20
CDCA3 cell division cycle associated 3
CDCA8 cell division cycle associated 8
CDK1 cyclin-dependent kinase 1
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CKS1B CDC28 protein kinase regulatory subunit 1B
CKS2 CDC28 protein kinase regulatory subunit 2
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
E2F8 E2F transcription factor 8
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FANCI Fanconi anemia, complementation group I
FEN1 flap structure-specific endonuclease 1
FOXM1 forkhead box M1
GINS2 GINS complex subunit 2 (Psf2 homolog)
GMNN geminin, DNA replication inhibitor
H2AFX H2A histone family, member X
HJURP Holliday junction recognition protein
HMGB2 high mobility group box 2
HMMR hyaluronan-mediated motility receptor (RHAMM)
KIAA0101 KIAA0101
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF18B kinesin family member 18B
KIF20A kinesin family member 20A
KIF4A kinesin family member 4A
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
MELK maternal embryonic leucine zipper kinase
MKI67 marker of proliferation Ki-67
MT1JP metallothionein 1J, pseudogene
NCAPD2 non-SMC condensin I complex, subunit D2
NCAPG non-SMC condensin I complex, subunit G
NDC80 NDC80 kinetochore complex component
NUSAP1 nucleolar and spindle associated protein 1
PCNA proliferating cell nuclear antigen
PLK1 polo-like kinase 1
PRC1 protein regulator of cytokinesis 1
PRIM1 primase, DNA, polypeptide 1 (49kDa)
RACGAP1 Rac GTPase activating protein 1
RAD51AP1 RAD51 associated protein 1
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
SHCBP1 SHC SH2-domain binding protein 1
SMC2 structural maintenance of chromosomes 2
SMC4 structural maintenance of chromosomes 4
TMPO thymopoietin
TOP2A topoisomerase (DNA) II alpha 170kDa
TPX2 TPX2, microtubule-associated
TTK TTK protein kinase
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
ZWINT ZW10 interacting kinetochore protein