CCNA2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description cyclin A2|The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 890)
External Link http://www.ncbi.nlm.nih.gov/gene/890
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355 interacting proteins for CCNA2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
AHNAK AHNAK nucleoprotein
AKAP11 A kinase (PRKA) anchor protein 11
AKAP2 A kinase (PRKA) anchor protein 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALB albumin
ANAPC1 anaphase promoting complex subunit 1
ANAPC11 anaphase promoting complex subunit 11
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC7 anaphase promoting complex subunit 7
ANXA4 annexin A4
ANXA8 annexin A8
ANXA8L1 annexin A8-like 1
ARF4 ADP-ribosylation factor 4
ARID4A AT rich interactive domain 4A (RBP1-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATAD3B ATPase family, AAA domain containing 3B
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
BABAM1 BRISC and BRCA1 A complex member 1
BAG5 BCL2-associated athanogene 5
BARD1 BRCA1 associated RING domain 1
BIRC6 baculoviral IAP repeat containing 6
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BSG basigin (Ok blood group)
BTG1 B-cell translocation gene 1, anti-proliferative
C2CD5 C2 calcium-dependent domain containing 5
CA2 carbonic anhydrase II
CABLES1 Cdk5 and Abl enzyme substrate 1
CABLES2 Cdk5 and Abl enzyme substrate 2
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CAPZB capping protein (actin filament) muscle Z-line, beta
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CCDC124 coiled-coil domain containing 124
CCDC8 coiled-coil domain containing 8
CCNA1 cyclin A1
CCNB1 cyclin B1
CCNB2 cyclin B2
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCNE1 cyclin E1
CCNE2 cyclin E2
CCNH cyclin H
CCNJ cyclin J
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDC27 cell division cycle 27
CDC6 cell division cycle 6
CDK1 cyclin-dependent kinase 1
CDK13 cyclin-dependent kinase 13
CDK17 cyclin-dependent kinase 17
CDK18 cyclin-dependent kinase 18
CDK2 cyclin-dependent kinase 2
CDK3 cyclin-dependent kinase 3
CDK4 cyclin-dependent kinase 4
CDK5 cyclin-dependent kinase 5
CDK6 cyclin-dependent kinase 6
CDK7 cyclin-dependent kinase 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDT1 chromatin licensing and DNA replication factor 1
CHAF1A chromatin assembly factor 1, subunit A (p150)
CKS1B CDC28 protein kinase regulatory subunit 1B
CKS2 CDC28 protein kinase regulatory subunit 2
COPS2 COP9 signalosome subunit 2
COPS5 COP9 signalosome subunit 5
COPS6 COP9 signalosome subunit 6
CORO1C coronin, actin binding protein, 1C
CPNE1 copine I
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CREBBP CREB binding protein
CTBP2 C-terminal binding protein 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL1 cullin 1
DCAF7 DDB1 and CUL4 associated factor 7
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DICER1 dicer 1, ribonuclease type III
DPY30 dpy-30 homolog (C. elegans)
DTNBP1 dystrobrevin binding protein 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
E2F4 E2F transcription factor 4, p107/p130-binding
E2F5 E2F transcription factor 5, p130-binding
EBNA1BP2 EBNA1 binding protein 2
EDC4 enhancer of mRNA decapping 4
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFTUD2 elongation factor Tu GTP binding domain containing 2
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF4A1 eukaryotic translation initiation factor 4A1
EIF6 eukaryotic translation initiation factor 6
ENAH enabled homolog (Drosophila)
EP300 E1A binding protein p300
EP400 E1A binding protein p400
ERP44 endoplasmic reticulum protein 44
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
EZR ezrin
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAM117A family with sequence similarity 117, member A
FAM117B family with sequence similarity 117, member B
FAM175A family with sequence similarity 175, member A
FAM175B family with sequence similarity 175, member B
FAM53C family with sequence similarity 53, member C
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FARSB phenylalanyl-tRNA synthetase, beta subunit
FEN1 flap structure-specific endonuclease 1
FIBP fibroblast growth factor (acidic) intracellular binding protein
FNTA farnesyltransferase, CAAX box, alpha
FNTB farnesyltransferase, CAAX box, beta
FOLR1 folate receptor 1 (adult)
FOXK1 forkhead box K1
FOXM1 forkhead box M1
FTSJ3 FtsJ homolog 3 (E. coli)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GDI2 GDP dissociation inhibitor 2
GLCCI1 glucocorticoid induced 1
GLTSCR2 glioma tumor suppressor candidate region gene 2
GLUD1 glutamate dehydrogenase 1
GMNN geminin, DNA replication inhibitor
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GOLGA2 golgin A2
GTPBP4 GTP binding protein 4
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRA histone cell cycle regulator
HIST1H1A histone cluster 1, H1a
HIST1H1B histone cluster 1, H1b
HIST1H1C histone cluster 1, H1c
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IDE insulin-degrading enzyme
IFRD1 interferon-related developmental regulator 1
IFT54 intraflagellar transport 54
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
IQGAP1 IQ motif containing GTPase activating protein 1
ISCU iron-sulfur cluster assembly enzyme
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
KAT2B K(lysine) acetyltransferase 2B
KAT8 K(lysine) acetyltransferase 8
KCTD17 potassium channel tetramerization domain containing 17
KIAA0195 KIAA0195
KIAA0232 KIAA0232
KIF24 kinesin family member 24
KRT1 keratin 1, type II
LIN37 lin-37 DREAM MuvB core complex component
LIN52 lin-52 DREAM MuvB core complex component
LIN54 lin-54 DREAM MuvB core complex component
LIN7C lin-7 homolog C (C. elegans)
LIN9 lin-9 DREAM MuvB core complex component
LYAR Ly1 antibody reactive
LZTS2 leucine zipper, putative tumor suppressor 2
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAPK15 mitogen-activated protein kinase 15
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
MCM8 minichromosome maintenance complex component 8
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MISP mitotic spindle positioning
MNAT1 MNAT CDK-activating kinase assembly factor 1
MOV10 Mov10 RISC complex RNA helicase
MSL3 male-specific lethal 3 homolog (Drosophila)
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NAE1 NEDD8 activating enzyme E1 subunit 1
NEXN nexilin (F actin binding protein)
NFYA nuclear transcription factor Y, alpha
NFYB nuclear transcription factor Y, beta
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NOP2 NOP2 nucleolar protein
NRD1 nardilysin (N-arginine dibasic convertase)
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
ORC1 origin recognition complex, subunit 1
ORC2 origin recognition complex, subunit 2
ORC3 origin recognition complex, subunit 3
ORC4 origin recognition complex, subunit 4
ORC5 origin recognition complex, subunit 5
ORC6 origin recognition complex, subunit 6
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PCNA proliferating cell nuclear antigen
PDLIM7 PDZ and LIM domain 7 (enigma)
PFAS phosphoribosylformylglycinamidine synthase
PGK1 phosphoglycerate kinase 1
PGR progesterone receptor
PHGDH phosphoglycerate dehydrogenase
PKM pyruvate kinase, muscle
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPL periplakin
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R3F protein phosphatase 1, regulatory subunit 3F
PRC1 protein regulator of cytokinesis 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRPF8 pre-mRNA processing factor 8
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTMA prothymosin, alpha
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PURA purine-rich element binding protein A
RAD23A RAD23 homolog A (S. cerevisiae)
RB1 retinoblastoma 1
RBBP4 retinoblastoma binding protein 4
RBL1 retinoblastoma-like 1
RBL2 retinoblastoma-like 2
RBX1 ring-box 1, E3 ubiquitin protein ligase
RFC4 replication factor C (activator 1) 4, 37kDa
RNF169 ring finger protein 169
RPA1 replication protein A1, 70kDa
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SAMHD1 SAM domain and HD domain 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIPA1L2 signal-induced proliferation-associated 1 like 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKI SKI proto-oncogene
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5)
SP1 Sp1 transcription factor
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPRR2A small proline-rich protein 2A
SPRR2B small proline-rich protein 2B
SPRR2E small proline-rich protein 2E
SPTBN2 spectrin, beta, non-erythrocytic 2
SSB Sjogren syndrome antigen B (autoantigen La)
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
STAU1 staufen double-stranded RNA binding protein 1
STAU2 staufen double-stranded RNA binding protein 2
STIP1 stress-induced phosphoprotein 1
SVIL supervillin
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TARBP2 TAR (HIV-1) RNA binding protein 2
TCOF1 Treacher Collins-Franceschetti syndrome 1
TCP1 t-complex 1
TECR trans-2,3-enoyl-CoA reductase
TFDP1 transcription factor Dp-1
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TJP1 tight junction protein 1
TMOD3 tropomodulin 3 (ubiquitous)
TOLLIP toll interacting protein
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TP73 tumor protein p73
TRAP1 TNF receptor-associated protein 1
TRIM29 tripartite motif containing 29
TRIM33 tripartite motif containing 33
TROAP trophinin associated protein
TYMP thymidine phosphorylase
UBA3 ubiquitin-like modifier activating enzyme 3
UBC ubiquitin C
UBTF upstream binding transcription factor, RNA polymerase I
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
UIMC1 ubiquitin interaction motif containing 1
USP11 ubiquitin specific peptidase 11
USP37 ubiquitin specific peptidase 37
WDR48 WD repeat domain 48
WDR6 WD repeat domain 6
WEE1 WEE1 G2 checkpoint kinase
XRN2 5'-3' exoribonuclease 2
ZNF346 zinc finger protein 346
ZNF516 zinc finger protein 516