| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cyclin D1|The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 595) |
| External Link | https://ncbi.nlm.nih.gov/gene/595 |
| Similar Terms | |
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499 genes differentially expressed following the CCND1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TLR4 | toll-like receptor 4 | 0.0196601 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0193288 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0184607 |
| RGS4 | regulator of G-protein signaling 4 | 0.0183674 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.0161498 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.0160448 |
| GPER1 | G protein-coupled estrogen receptor 1 | 0.0155013 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.015432 |
| IDE | insulin-degrading enzyme | 0.0149998 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.0149282 |
| CNTN1 | contactin 1 | 0.0147669 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0146473 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.0146197 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0146003 |
| PLAT | plasminogen activator, tissue | 0.0144306 |
| PENK | proenkephalin | 0.0142694 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0140163 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.0139614 |
| IL1B | interleukin 1, beta | 0.0138067 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.0133622 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.0131283 |
| EREG | epiregulin | 0.0130934 |
| IFI30 | interferon, gamma-inducible protein 30 | 0.0127249 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0126319 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.0126147 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | 0.0125923 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0125491 |
| KRT14 | keratin 14, type I | 0.0125482 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.0125386 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.0124216 |
| LY96 | lymphocyte antigen 96 | 0.0124014 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.0122768 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0122629 |
| KRT6A | keratin 6A, type II | 0.0121606 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.0117963 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0116626 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.0116324 |
| SIRT3 | sirtuin 3 | 0.0115433 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0114482 |
| TXNDC9 | thioredoxin domain containing 9 | 0.0113749 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.0113501 |
| CSTA | cystatin A (stefin A) | 0.0113479 |
| RCAN1 | regulator of calcineurin 1 | 0.0113119 |
| IL1RN | interleukin 1 receptor antagonist | 0.0112443 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.0111174 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.0110173 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0109789 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0108788 |
| POU2AF1 | POU class 2 associating factor 1 | 0.0108657 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0108325 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.0107852 |
| TUBB6 | tubulin, beta 6 class V | 0.0107061 |
| LAMC2 | laminin, gamma 2 | 0.0106543 |
| THBD | thrombomodulin | 0.0105496 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0105075 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0104926 |
| PLXNC1 | plexin C1 | 0.0103963 |
| LAMB3 | laminin, beta 3 | 0.0103963 |
| DACH1 | dachshund family transcription factor 1 | 0.0103763 |
| MMP2 | matrix metallopeptidase 2 | 0.0103752 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.0103464 |
| FOXG1 | forkhead box G1 | 0.0103403 |
| DIPK1A | divergent protein kinase domain 1A | 0.0103116 |
| RBM34 | RNA binding motif protein 34 | 0.0102903 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0102772 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.010272 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.0102535 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.0102393 |
| COL1A1 | collagen, type I, alpha 1 | 0.0102294 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.01022 |
| TPBG | trophoblast glycoprotein | 0.0102165 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0102143 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.0101967 |
| MEF2C | myocyte enhancer factor 2C | 0.0101915 |
| SIRPA | signal-regulatory protein alpha | 0.010175 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.0101635 |
| PLK2 | polo-like kinase 2 | 0.0101335 |
| GPC4 | glypican 4 | 0.0101235 |
| ARPP21 | cAMP-regulated phosphoprotein, 21kDa | 0.0101143 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0101065 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0100939 |
| S100P | S100 calcium binding protein P | 0.0100799 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0100427 |
| ACOT9 | acyl-CoA thioesterase 9 | 0.0100286 |
| NNMT | nicotinamide N-methyltransferase | 0.00999349 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00999033 |
| THBS2 | thrombospondin 2 | 0.0099611 |
| KRT17 | keratin 17, type I | 0.00992151 |
| IL6 | interleukin 6 | 0.0098961 |
| RIN2 | Ras and Rab interactor 2 | 0.00984346 |
| CEL | carboxyl ester lipase | 0.00977513 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.00970146 |
| LAMA2 | laminin, alpha 2 | 0.0097007 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.00962526 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00955191 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00952236 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00951798 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.00951793 |
| DCN | decorin | 0.00949018 |
| PRR16 | proline rich 16 | 0.00948032 |
| SDS | serine dehydratase | 0.00947037 |
| RAB13 | RAB13, member RAS oncogene family | 0.00947012 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00941105 |
| TNC | tenascin C | 0.00940076 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00939616 |
| JAG1 | jagged 1 | 0.00936454 |
| PCDH9 | protocadherin 9 | 0.00936407 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0093241 |
| TPM2 | tropomyosin 2 (beta) | 0.00928109 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.00921456 |
| VNN1 | vanin 1 | 0.00920655 |
| EHD3 | EH-domain containing 3 | 0.0091849 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00917752 |
| ZFHX4 | zinc finger homeobox 4 | 0.00913103 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00911082 |
| MAGED1 | melanoma antigen family D1 | 0.00911041 |
| TP63 | tumor protein p63 | 0.00900802 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.00899619 |
| CTBP2 | C-terminal binding protein 2 | 0.00897532 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00894184 |
| RAB40B | RAB40B, member RAS oncogene family | 0.00890122 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00889864 |
| SIX2 | SIX homeobox 2 | 0.00887175 |
| LUM | lumican | 0.00886577 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00881586 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00879781 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00879633 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00879063 |
| CALHM2 | calcium homeostasis modulator 2 | 0.00876812 |
| CD52 | CD52 molecule | 0.00873418 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00861544 |
| DUSP3 | dual specificity phosphatase 3 | 0.00858438 |
| TGM2 | transglutaminase 2 | 0.0085814 |
| FLT3 | fms-related tyrosine kinase 3 | 0.00857629 |
| STK10 | serine/threonine kinase 10 | 0.00855226 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00848419 |
| OPN3 | opsin 3 | 0.00848383 |
| ANO3 | anoctamin 3 | 0.00848098 |
| S100A7 | S100 calcium binding protein A7 | 0.00847332 |
| MMP19 | matrix metallopeptidase 19 | 0.00845772 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00845375 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00844831 |
| LDB2 | LIM domain binding 2 | 0.00838745 |
| DNASE2 | deoxyribonuclease II, lysosomal | 0.00834335 |
| PLIN3 | perilipin 3 | 0.00831542 |
| MICU2 | mitochondrial calcium uptake 2 | 0.00831268 |
| HAL | histidine ammonia-lyase | 0.0083101 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | 0.00828904 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00826535 |
| PTGES | prostaglandin E synthase | 0.00821453 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 0.00816097 |
| SPRR1B | small proline-rich protein 1B | 0.00815186 |
| PLEK | pleckstrin | 0.00814143 |
| LEPR | leptin receptor | 0.00814103 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00813276 |
| PRAF2 | PRA1 domain family, member 2 | 0.00812772 |
| FBN1 | fibrillin 1 | 0.00811631 |
| TSNAX | translin-associated factor X | 0.00807364 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.00805572 |
| CLCA2 | chloride channel accessory 2 | 0.00804737 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0080217 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00800995 |
| CD81 | CD81 molecule | 0.00800884 |
| RNF167 | ring finger protein 167 | 0.0079573 |
| HES1 | hes family bHLH transcription factor 1 | 0.00794499 |
| CA12 | carbonic anhydrase XII | 0.00794181 |
| SULF1 | sulfatase 1 | 0.00793848 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.00793823 |
| BMP2 | bone morphogenetic protein 2 | 0.00792071 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | 0.00787633 |
| RGS3 | regulator of G-protein signaling 3 | 0.00787135 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00785621 |
| TMEM47 | transmembrane protein 47 | 0.00782879 |
| CD84 | CD84 molecule | 0.00782358 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00781072 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00780989 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.00779787 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00778261 |
| DST | dystonin | 0.0077753 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00776774 |
| TRIM8 | tripartite motif containing 8 | 0.00774411 |
| DDN | dendrin | 0.00774349 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.00773227 |
| TAC1 | tachykinin, precursor 1 | 0.00772367 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.00770412 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.00769188 |
| EXOSC4 | exosome component 4 | 0.00766352 |
| AK5 | adenylate kinase 5 | 0.00765847 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.00765753 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00765641 |
| DSE | dermatan sulfate epimerase | 0.00765122 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00763942 |
| BIN1 | bridging integrator 1 | 0.00763762 |
| DUSP7 | dual specificity phosphatase 7 | 0.00762464 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.00760564 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.00760419 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00760182 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00758167 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00757665 |
| SFN | stratifin | 0.00754812 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00753645 |
| METRN | meteorin, glial cell differentiation regulator | 0.00752328 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.00752044 |
| RGS14 | regulator of G-protein signaling 14 | 0.00751669 |
| RABAC1 | Rab acceptor 1 (prenylated) | 0.00750568 |
| MAP7 | microtubule-associated protein 7 | 0.00749517 |
| CH25H | cholesterol 25-hydroxylase | 0.00746237 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.00745945 |
| POPDC3 | popeye domain containing 3 | 0.00745756 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00744941 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00744667 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.0074386 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00738471 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00736693 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00736608 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00734943 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00733152 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00733074 |
| ITGA8 | integrin, alpha 8 | 0.00732243 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00731423 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.00730497 |
| CTSW | cathepsin W | 0.00728537 |
| COL5A1 | collagen, type V, alpha 1 | 0.00726531 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00726215 |
| SP110 | SP110 nuclear body protein | 0.0072383 |
| AUTS2 | autism susceptibility candidate 2 | 0.00722987 |
| AIM2 | absent in melanoma 2 | 0.00722714 |
| STAB1 | stabilin 1 | 0.0072172 |
| MFAP4 | microfibrillar-associated protein 4 | 0.00720736 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00720246 |
| NAV3 | neuron navigator 3 | 0.00719642 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00719551 |
| SNAI2 | snail family zinc finger 2 | 0.00719106 |
| TRAF5 | TNF receptor-associated factor 5 | 0.00717414 |
| KRT6B | keratin 6B, type II | 0.00711025 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.00710586 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00708683 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.00706513 |
| ABR | active BCR-related | 0.00706059 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0070549 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 0.00705353 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00702446 |
| MTARC2 | mitochondrial amidoxime reducing component 2 | 0.00702404 |
| RAB6A | RAB6A, member RAS oncogene family | 0.00701718 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0070145 |
| SASH3 | SAM and SH3 domain containing 3 | 0.00701044 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.00700544 |
| CLEC7A | C-type lectin domain family 7, member A | 0.0069952 |
| KCNJ4 | potassium channel, inwardly rectifying subfamily J, member 4 | 0.0069839 |
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | -0.0237103 |
| TMSB15A | thymosin beta 15a | -0.0203197 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.018849 |
| BEX1 | brain expressed, X-linked 1 | -0.0184787 |
| NRCAM | neuronal cell adhesion molecule | -0.0176641 |
| RGCC | regulator of cell cycle | -0.0170381 |
| CA2 | carbonic anhydrase II | -0.0169469 |
| PROM1 | prominin 1 | -0.0163166 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.0150722 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.0149805 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0149412 |
| TSPAN12 | tetraspanin 12 | -0.0146802 |
| COQ8A | coenzyme Q8A | -0.0144572 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.0142191 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0140848 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.0136485 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.0136177 |
| MDFIC | MyoD family inhibitor domain containing | -0.0134829 |
| CHKB | choline kinase beta | -0.0133884 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0132788 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0131758 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.0131045 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0128918 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0128828 |
| ELOVL2 | ELOVL fatty acid elongase 2 | -0.0126923 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0125684 |
| FABP7 | fatty acid binding protein 7, brain | -0.0123083 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0122888 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0122634 |
| MAMLD1 | mastermind-like domain containing 1 | -0.0119832 |
| MMP11 | matrix metallopeptidase 11 | -0.011962 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.011955 |
| PODXL | podocalyxin-like | -0.0118756 |
| PDZK1 | PDZ domain containing 1 | -0.0118069 |
| PEG3 | paternally expressed 3 | -0.0114755 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0114492 |
| KRT8 | keratin 8, type II | -0.0114183 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.0113081 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.0112463 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.0110879 |
| EXPH5 | exophilin 5 | -0.0110877 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0110301 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0108258 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0108092 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0106881 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0106681 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0104874 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.0104474 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0104249 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | -0.0104039 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.0103461 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.0103429 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -0.0103276 |
| REEP1 | receptor accessory protein 1 | -0.0102732 |
| CANT1 | calcium activated nucleotidase 1 | -0.0102597 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.0101301 |
| MARCKSL1 | MARCKS-like 1 | -0.0101189 |
| TCP1 | t-complex 1 | -0.0100792 |
| PTCH1 | patched 1 | -0.0100619 |
| ELANE | elastase, neutrophil expressed | -0.00996888 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | -0.00996476 |
| CES1 | carboxylesterase 1 | -0.00985907 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.0098283 |
| KIF20A | kinesin family member 20A | -0.00981855 |
| H1-2 | H1.2 linker histone, cluster member | -0.0097924 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | -0.00978141 |
| IL17RB | interleukin 17 receptor B | -0.00972969 |
| TLE2 | transducin-like enhancer of split 2 | -0.00971045 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00968836 |
| FCGBP | Fc fragment of IgG binding protein | -0.00960642 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00957962 |
| A2M | alpha-2-macroglobulin | -0.00956115 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00955965 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0094711 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00938995 |
| GPR161 | G protein-coupled receptor 161 | -0.009373 |
| TMEM255A | transmembrane protein 255A | -0.00934674 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00932117 |
| PNMA8A | PNMA family member 8A | -0.00930235 |
| S100A10 | S100 calcium binding protein A10 | -0.00926123 |
| CD83 | CD83 molecule | -0.00925428 |
| ATF3 | activating transcription factor 3 | -0.00921048 |
| PGF | placental growth factor | -0.00920231 |
| CP | ceruloplasmin (ferroxidase) | -0.00920133 |
| SORBS3 | sorbin and SH3 domain containing 3 | -0.00918837 |
| DLD | dihydrolipoamide dehydrogenase | -0.00916353 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00915905 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00914664 |
| KIF1B | kinesin family member 1B | -0.00912305 |
| HHEX | hematopoietically expressed homeobox | -0.00912257 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00911369 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00907498 |
| HOXB7 | homeobox B7 | -0.00905728 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00900662 |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase | -0.00898963 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00898256 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.00894739 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.00893565 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.00892178 |
| PRTN3 | proteinase 3 | -0.00887673 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00881546 |
| CDC20 | cell division cycle 20 | -0.0087725 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.00876723 |
| STXBP6 | syntaxin binding protein 6 (amisyn) | -0.00874846 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00872474 |
| SSPN | sarcospan | -0.00870411 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | -0.00868491 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.0086728 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.00857275 |
| MLLT4-AS1 | MLLT4 antisense RNA 1 (head to head) | -0.00852969 |
| EZR | ezrin | -0.00852036 |
| TADA2A | transcriptional adaptor 2A | -0.00850255 |
| SCGN | secretagogin, EF-hand calcium binding protein | -0.00845184 |
| FAM169A | family with sequence similarity 169, member A | -0.00843714 |
| PAGE4 | P antigen family, member 4 (prostate associated) | -0.00840838 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | -0.0083834 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.00835294 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00834471 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.008341 |
| ALB | albumin | -0.00833753 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00831079 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00828026 |
| MED28 | mediator complex subunit 28 | -0.00826177 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00824214 |
| GOLM1 | golgi membrane protein 1 | -0.00822833 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00818773 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.00818142 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.0081602 |
| DIRAS2 | DIRAS family, GTP-binding RAS-like 2 | -0.00815376 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.0081508 |
| CD93 | CD93 molecule | -0.00814896 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00814015 |
| AK4 | adenylate kinase 4 | -0.00812597 |
| CADM1 | cell adhesion molecule 1 | -0.00811635 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00811118 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.00810825 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00806506 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 | -0.0080616 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00805825 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.00801687 |
| SNX10 | sorting nexin 10 | -0.00798816 |
| CRIP2 | cysteine-rich protein 2 | -0.00797798 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00797348 |
| EGF | epidermal growth factor | -0.00797297 |
| INSM1 | insulinoma-associated 1 | -0.00791001 |
| MT1F | metallothionein 1F | -0.0078825 |
| WTAP | Wilms tumor 1 associated protein | -0.00786104 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00786062 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | -0.00786027 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.00785536 |
| CBS | cystathionine-beta-synthase | -0.00785223 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00781096 |
| KRT23 | keratin 23, type I | -0.0077949 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.00777049 |
| OLFM4 | olfactomedin 4 | -0.00776935 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | -0.00775942 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | -0.00773039 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00772208 |
| STAT5B | signal transducer and activator of transcription 5B | -0.00771676 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00770576 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.00769011 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.0076626 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | -0.00765358 |
| CD44 | CD44 molecule (Indian blood group) | -0.00763763 |
| TXN | thioredoxin | -0.00762682 |
| GOLT1B | golgi transport 1B | -0.00760389 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic | -0.00758845 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00756431 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.00756389 |
| AHSG | alpha-2-HS-glycoprotein | -0.00751161 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00751027 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 | -0.0075027 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00749786 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.00749342 |
| GLUD1 | glutamate dehydrogenase 1 | -0.00749203 |
| PDE9A | phosphodiesterase 9A | -0.00748267 |
| NEUROD1 | neuronal differentiation 1 | -0.00746511 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00744379 |
| TSPAN7 | tetraspanin 7 | -0.00744029 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00743225 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | -0.00742709 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0073895 |
| RAB33A | RAB33A, member RAS oncogene family | -0.00738773 |
| SEPTIN4 | septin 4 | -0.00737802 |
| CIB2 | calcium and integrin binding family member 2 | -0.0073773 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.00737567 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00735539 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00732733 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00731582 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00730939 |
| H1-10 | H1.10 linker histone | -0.00726244 |
| FOLR1 | folate receptor 1 (adult) | -0.00723867 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00722994 |
| HMGN1 | high mobility group nucleosome binding domain 1 | -0.00722595 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00721556 |
| CCNE2 | cyclin E2 | -0.00721511 |
| PRKD3 | protein kinase D3 | -0.00719676 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | -0.00719083 |
| HPSE | heparanase | -0.00717854 |
| HMGB2 | high mobility group box 2 | -0.00714634 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00714111 |
| CTNNBL1 | catenin, beta like 1 | -0.00713526 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00713268 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0071323 |
| INHBB | inhibin, beta B | -0.00711326 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.00709311 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | -0.00709138 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.0070848 |
| TBP | TATA box binding protein | -0.007082 |
| ANXA3 | annexin A3 | -0.00707238 |
| CHGB | chromogranin B | -0.00706464 |
| PAX6 | paired box 6 | -0.00705253 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -0.00703686 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | -0.00697888 |
| DMD | dystrophin | -0.00697274 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00696513 |
| HK2 | hexokinase 2 | -0.00696473 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00696417 |
| GMPR | guanosine monophosphate reductase | -0.00696055 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00694822 |
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | -0.0069434 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.00693378 |
| PMP2 | peripheral myelin protein 2 | -0.00692328 |
| RNPEP | arginyl aminopeptidase (aminopeptidase B) | -0.00691925 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.00690725 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | -0.00690643 |
| TENM1 | teneurin transmembrane protein 1 | -0.00690331 |
| MAGOH | mago-nashi homolog, proliferation-associated (Drosophila) | -0.00690291 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.00688695 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.00688069 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.0068712 |
| PRPF4B | pre-mRNA processing factor 4B | -0.00684238 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00684232 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00683394 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00682343 |
| FERMT2 | fermitin family member 2 | -0.00682156 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.00681591 |
| UNC13B | unc-13 homolog B (C. elegans) | -0.00679996 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00679794 |
| TLCD3A | TLC domain containing 3A | -0.00676463 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00676071 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | -0.006743 |
| TMEM14B | transmembrane protein 14B | -0.00673311 |
| CDC45 | cell division cycle 45 | -0.00670728 |
| APOA2 | apolipoprotein A-II | -0.00669853 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -0.00669433 |
| ARRB2 | arrestin, beta 2 | -0.00667212 |
| NID1 | nidogen 1 | -0.00665671 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.00665614 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0066185 |
