| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cyclin D2|The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3). [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 894) |
| External Link | https://ncbi.nlm.nih.gov/gene/894 |
| Similar Terms | |
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498 genes differentially expressed following the CCND2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0201219 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.017448 |
| S100P | S100 calcium binding protein P | 0.0172118 |
| GNAS | GNAS complex locus | 0.016834 |
| MAGEA3 | melanoma antigen family A3 | 0.016621 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0162531 |
| DEFB1 | defensin, beta 1 | 0.015961 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0159201 |
| ANXA3 | annexin A3 | 0.0156673 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0156617 |
| KYNU | kynureninase | 0.0156469 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0152664 |
| RGCC | regulator of cell cycle | 0.0150942 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0148725 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0146994 |
| IL6ST | interleukin 6 signal transducer | 0.014493 |
| REEP5 | receptor accessory protein 5 | 0.0141453 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.0137245 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0137136 |
| MAL | mal, T-cell differentiation protein | 0.0135384 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0134677 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0133821 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0133667 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0130456 |
| EGR2 | early growth response 2 | 0.0128047 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0127211 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0127159 |
| MAGEA12 | melanoma antigen family A12 | 0.0126398 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0126151 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.012507 |
| ANXA1 | annexin A1 | 0.0124806 |
| PRNP | prion protein | 0.0124732 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.0123902 |
| SPRR3 | small proline-rich protein 3 | 0.0120632 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0118499 |
| MT2A | metallothionein 2A | 0.0118411 |
| KRT13 | keratin 13, type I | 0.0117808 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0116855 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0116196 |
| NCOA4 | nuclear receptor coactivator 4 | 0.0115359 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0114605 |
| KRT7 | keratin 7, type II | 0.0114279 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0113547 |
| LEPROT | leptin receptor overlapping transcript | 0.0113474 |
| CD93 | CD93 molecule | 0.0110786 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0110687 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0109788 |
| C3 | complement component 3 | 0.0108249 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0106902 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0106266 |
| BMP4 | bone morphogenetic protein 4 | 0.010623 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0105885 |
| TRAM1 | translocation associated membrane protein 1 | 0.0105545 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0104767 |
| DAZAP2 | DAZ associated protein 2 | 0.0104215 |
| STOM | stomatin | 0.0103823 |
| PSCA | prostate stem cell antigen | 0.0103157 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 0.010297 |
| IFI44 | interferon-induced protein 44 | 0.0102694 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.0101302 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0100974 |
| MYO1C | myosin IC | 0.010028 |
| KRT81 | keratin 81, type II | 0.0100205 |
| MSMB | microseminoprotein, beta- | 0.00988336 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00986432 |
| PROM1 | prominin 1 | 0.00985494 |
| SHTN1 | shootin 1 | 0.00982261 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00980231 |
| AGPS | alkylglycerone phosphate synthase | 0.00979832 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00978168 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00975373 |
| IFI44L | interferon-induced protein 44-like | 0.00974583 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0097079 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00962344 |
| YIPF5 | Yip1 domain family, member 5 | 0.00961254 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00959288 |
| FOXG1 | forkhead box G1 | 0.00957734 |
| TGM2 | transglutaminase 2 | 0.009527 |
| PRAME | preferentially expressed antigen in melanoma | 0.00950932 |
| FN1 | fibronectin 1 | 0.00940476 |
| PFKP | phosphofructokinase, platelet | 0.00937533 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00937287 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00935785 |
| RNASET2 | ribonuclease T2 | 0.0092843 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00927054 |
| S100A7 | S100 calcium binding protein A7 | 0.00926684 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00923134 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00919027 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00918063 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00916659 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0091617 |
| MUC16 | mucin 16, cell surface associated | 0.00915589 |
| DSG2 | desmoglein 2 | 0.00906502 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.0090525 |
| CAV2 | caveolin 2 | 0.00901928 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00899187 |
| IL6 | interleukin 6 | 0.00897384 |
| KRT17 | keratin 17, type I | 0.00896041 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00893939 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.00893147 |
| HSPE1 | heat shock 10kDa protein 1 | 0.00892484 |
| MT1F | metallothionein 1F | 0.00892111 |
| CFAP20 | cilia and flagella associated protein 20 | 0.00889266 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00888932 |
| MT1X | metallothionein 1X | 0.0088721 |
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 0.00885356 |
| CP | ceruloplasmin (ferroxidase) | 0.00884368 |
| MX2 | MX dynamin-like GTPase 2 | 0.0088363 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00877859 |
| MIR22HG | MIR22 host gene | 0.0087551 |
| BTG3 | BTG family, member 3 | 0.00871934 |
| KIF5C | kinesin family member 5C | 0.0086371 |
| FOLR1 | folate receptor 1 (adult) | 0.00862675 |
| ALB | albumin | 0.00859676 |
| TMEM59 | transmembrane protein 59 | 0.00857289 |
| BTG2 | BTG family, member 2 | 0.00856416 |
| MCL1 | myeloid cell leukemia 1 | 0.00855666 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00855569 |
| TSPAN8 | tetraspanin 8 | 0.00850141 |
| MSLN | mesothelin | 0.00849664 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00849268 |
| TJP2 | tight junction protein 2 | 0.00849109 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.0084775 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0084699 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00845112 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0084274 |
| ABLIM1 | actin binding LIM protein 1 | 0.00841091 |
| CFI | complement factor I | 0.00839125 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00834331 |
| STATH | statherin | 0.00831418 |
| KRT18 | keratin 18, type I | 0.00829031 |
| TFDP1 | transcription factor Dp-1 | 0.00828874 |
| MT1E | metallothionein 1E | 0.00827933 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00827904 |
| CTSC | cathepsin C | 0.00827843 |
| CTSB | cathepsin B | 0.00825139 |
| LAMB3 | laminin, beta 3 | 0.00822173 |
| IL27RA | interleukin 27 receptor, alpha | 0.00820752 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00820632 |
| YIPF6 | Yip1 domain family, member 6 | 0.00819765 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 0.00818861 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00818467 |
| IQCG | IQ motif containing G | 0.00817833 |
| ERGIC2 | ERGIC and golgi 2 | 0.00817484 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.00816476 |
| LYRM2 | LYR motif containing 2 | 0.0081638 |
| LAMC2 | laminin, gamma 2 | 0.00815597 |
| PEG3 | paternally expressed 3 | 0.0081515 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00813765 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00813424 |
| JPT2 | Jupiter microtubule associated homolog 2 | 0.00811302 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00808477 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00806929 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.00806399 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00796575 |
| PPIF | peptidylprolyl isomerase F | 0.00796519 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00794656 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00793767 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00792909 |
| RPN2 | ribophorin II | 0.00791735 |
| CANX | calnexin | 0.00790916 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00790903 |
| SP110 | SP110 nuclear body protein | 0.00790754 |
| KLK10 | kallikrein-related peptidase 10 | 0.00789495 |
| COG7 | component of oligomeric golgi complex 7 | 0.0078803 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.00786936 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00786933 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.00785178 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00784962 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00784193 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.00783136 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0078301 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.00782004 |
| MT1H | metallothionein 1H | 0.00781929 |
| AK4 | adenylate kinase 4 | 0.0078121 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00780929 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.0078087 |
| ARG2 | arginase 2 | 0.00778612 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00778319 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00778169 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | 0.00778027 |
| DCLRE1C | DNA cross-link repair 1C | 0.00777861 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00777717 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00776272 |
| KLK6 | kallikrein-related peptidase 6 | 0.00774369 |
| MAGED2 | melanoma antigen family D2 | 0.00772558 |
| RAB33A | RAB33A, member RAS oncogene family | 0.00770277 |
| NMD3 | NMD3 ribosome export adaptor | 0.00769019 |
| PRKCH | protein kinase C, eta | 0.0076821 |
| ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 | 0.00767457 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.00767456 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00766817 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00765592 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00765536 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.00765466 |
| EXOC5 | exocyst complex component 5 | 0.00764289 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00764017 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00763113 |
| OPTN | optineurin | 0.00761138 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.00760251 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00759838 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00759727 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00756614 |
| CCNG1 | cyclin G1 | 0.00756595 |
| COPA | coatomer protein complex, subunit alpha | 0.00756186 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00754972 |
| CCDC6 | coiled-coil domain containing 6 | 0.00754733 |
| ATP5F1C | ATP synthase F1 subunit gamma | 0.00753902 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.00753546 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.00752968 |
| ITGA6 | integrin, alpha 6 | 0.0075081 |
| HHEX | hematopoietically expressed homeobox | 0.00748918 |
| SET | SET nuclear proto-oncogene | 0.00747013 |
| PEX2 | peroxisomal biogenesis factor 2 | 0.0074599 |
| SP100 | SP100 nuclear antigen | 0.00744928 |
| ZNF706 | zinc finger protein 706 | 0.00744125 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.0074377 |
| CLDN10 | claudin 10 | 0.00742599 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 0.00741991 |
| RGS10 | regulator of G-protein signaling 10 | 0.00739955 |
| EFNA1 | ephrin-A1 | 0.00738928 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00737844 |
| ORM1 | orosomucoid 1 | 0.0073659 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00735697 |
| BST2 | bone marrow stromal cell antigen 2 | 0.0073533 |
| TRIM22 | tripartite motif containing 22 | 0.0073425 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00733699 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00732854 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00727625 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00727009 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.00726791 |
| WSB2 | WD repeat and SOCS box containing 2 | 0.00726275 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0072578 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.00725483 |
| PITX1 | paired-like homeodomain 1 | 0.0072488 |
| VDAC2 | voltage-dependent anion channel 2 | 0.00724808 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00723858 |
| FGG | fibrinogen gamma chain | 0.00723455 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00723047 |
| VWF | von Willebrand factor | 0.0072258 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 0.00722476 |
| HOMER1 | homer scaffolding protein 1 | 0.00721593 |
| ODAM | odontogenic, ameloblast asssociated | 0.00721034 |
| NELL2 | NEL-like 2 (chicken) | 0.00720793 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 | 0.0071895 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00718739 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00718346 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00718253 |
| SLC25A46 | solute carrier family 25, member 46 | 0.00717771 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -0.0283861 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0219477 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0207679 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0198073 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0196521 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.0188848 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0164565 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.014806 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.0145533 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.0144499 |
| FASN | fatty acid synthase | -0.0142486 |
| MMP9 | matrix metallopeptidase 9 | -0.0139324 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0136708 |
| CA12 | carbonic anhydrase XII | -0.0131298 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0131025 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.0130283 |
| TFF3 | trefoil factor 3 (intestinal) | -0.013 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0126674 |
| RAPSN | receptor-associated protein of the synapse | -0.0124399 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0122209 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.0119843 |
| EFNB2 | ephrin-B2 | -0.0117745 |
| CD320 | CD320 molecule | -0.0116863 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.011632 |
| SPON2 | spondin 2, extracellular matrix protein | -0.011484 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.0114614 |
| CD81 | CD81 molecule | -0.0111675 |
| PDZK1 | PDZ domain containing 1 | -0.0108196 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.0107269 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.0104443 |
| AUTS2 | autism susceptibility candidate 2 | -0.0103495 |
| COMP | cartilage oligomeric matrix protein | -0.0103176 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.0102761 |
| ECM1 | extracellular matrix protein 1 | -0.0102733 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.0102199 |
| AEBP1 | AE binding protein 1 | -0.0102097 |
| INTS1 | integrator complex subunit 1 | -0.0100845 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.0100001 |
| LMNB2 | lamin B2 | -0.00992994 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0097958 |
| KIAA0226L | KIAA0226-like | -0.00976652 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00973969 |
| TSPAN12 | tetraspanin 12 | -0.00967561 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00963577 |
| HMGB2 | high mobility group box 2 | -0.00961534 |
| HEPH | hephaestin | -0.00952097 |
| HOPX | HOP homeobox | -0.00950618 |
| IPO13 | importin 13 | -0.00949456 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00940143 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.00928501 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.00922372 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00920311 |
| PCDH9 | protocadherin 9 | -0.00917681 |
| AGR2 | anterior gradient 2 | -0.009137 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00913046 |
| PRODH | proline dehydrogenase (oxidase) 1 | -0.00909652 |
| PFKM | phosphofructokinase, muscle | -0.00908072 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00907893 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00901565 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00900003 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00888586 |
| FOXM1 | forkhead box M1 | -0.00886742 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00884016 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00883676 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00878142 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00877264 |
| REG3A | regenerating islet-derived 3 alpha | -0.00871321 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.0086732 |
| CCNF | cyclin F | -0.00865015 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | -0.00863274 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00862477 |
| CTBP2 | C-terminal binding protein 2 | -0.00858978 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | -0.00858652 |
| DGKZ | diacylglycerol kinase, zeta | -0.00856833 |
| LRRC15 | leucine rich repeat containing 15 | -0.00851179 |
| EPHB6 | EPH receptor B6 | -0.00849462 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic | -0.00843243 |
| AMACR | alpha-methylacyl-CoA racemase | -0.0084126 |
| XYLT1 | xylosyltransferase I | -0.00840545 |
| NOTCH1 | notch 1 | -0.00838978 |
| KRT2 | keratin 2, type II | -0.00835631 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00835355 |
| CDC20 | cell division cycle 20 | -0.00832611 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 | -0.00832361 |
| EHD2 | EH-domain containing 2 | -0.00832098 |
| SMYD3 | SET and MYND domain containing 3 | -0.00828411 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00828229 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00826885 |
| GRAMD4 | GRAM domain containing 4 | -0.00825788 |
| GAL | galanin/GMAP prepropeptide | -0.00822534 |
| ELN | elastin | -0.00822338 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00821507 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00819011 |
| KIAA0930 | KIAA0930 | -0.00815404 |
| PNKP | polynucleotide kinase 3'-phosphatase | -0.00809879 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00805952 |
| HDC | histidine decarboxylase | -0.00804076 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00803478 |
| RAB25 | RAB25, member RAS oncogene family | -0.00801357 |
| DACH1 | dachshund family transcription factor 1 | -0.00800849 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00800455 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.00797119 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00793903 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00792828 |
| SMTN | smoothelin | -0.00790759 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.0078978 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00789754 |
| HMG20B | high mobility group 20B | -0.00789576 |
| CRYM | crystallin, mu | -0.00789487 |
| CD84 | CD84 molecule | -0.00788517 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00784821 |
| APOD | apolipoprotein D | -0.00782177 |
| POLD2 | polymerase (DNA directed), delta 2, accessory subunit | -0.00781204 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00780956 |
| THOC6 | THO complex 6 | -0.00780272 |
| THBS4 | thrombospondin 4 | -0.00778301 |
| DSC1 | desmocollin 1 | -0.00776862 |
| STK26 | serine/threonine protein kinase 26 | -0.00776078 |
| ITGA7 | integrin, alpha 7 | -0.00775205 |
| TSPAN13 | tetraspanin 13 | -0.0076939 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.00769105 |
| ZNF589 | zinc finger protein 589 | -0.0076843 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | -0.00767423 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00767052 |
| VPREB3 | pre-B lymphocyte 3 | -0.00766938 |
| TNC | tenascin C | -0.00766569 |
| CLC | Charcot-Leyden crystal galectin | -0.00764958 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00764529 |
| TARDBP | TAR DNA binding protein | -0.00762498 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00760983 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00760939 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00760905 |
| LSR | lipolysis stimulated lipoprotein receptor | -0.00760454 |
| CDC25B | cell division cycle 25B | -0.00760132 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | -0.00759723 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.00759436 |
| GUSB | glucuronidase, beta | -0.00759058 |
| BCL7A | B-cell CLL/lymphoma 7A | -0.0075756 |
| MACROD1 | MACRO domain containing 1 | -0.00756544 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.00755181 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 | -0.00753408 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | -0.00752606 |
| TRIM28 | tripartite motif containing 28 | -0.00751566 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00750994 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00750921 |
| TSPAN4 | tetraspanin 4 | -0.00750056 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00748029 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.00745586 |
| CTSD | cathepsin D | -0.00741238 |
| THY1 | Thy-1 cell surface antigen | -0.00741048 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.00740926 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00740407 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00739772 |
| HMGB3 | high mobility group box 3 | -0.00738582 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | -0.00736092 |
| PPA2 | pyrophosphatase (inorganic) 2 | -0.00735575 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.00734859 |
| PLPP3 | phospholipid phosphatase 3 | -0.00733993 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.00733929 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00732168 |
| ENAH | enabled homolog (Drosophila) | -0.00731383 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00731355 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | -0.00730869 |
| MAOA | monoamine oxidase A | -0.00726905 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00726539 |
| ATG4B | autophagy related 4B, cysteine peptidase | -0.00726434 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00725955 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00724807 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00724504 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | -0.00724205 |
| NOX1 | NADPH oxidase 1 | -0.00724084 |
| REX1BD | required for excision 1-B domain containing | -0.00723755 |
| CEP70 | centrosomal protein 70kDa | -0.00723417 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00721576 |
| DSG1 | desmoglein 1 | -0.00721291 |
| CENPT | centromere protein T | -0.00720205 |
| TRAPPC6A | trafficking protein particle complex 6A | -0.00718149 |
| LOR | loricrin | -0.0071796 |
| POSTN | periostin, osteoblast specific factor | -0.00713917 |
| NEO1 | neogenin 1 | -0.00713477 |
| MLPH | melanophilin | -0.00713126 |
| ITGA8 | integrin, alpha 8 | -0.00711516 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00711002 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -0.00710767 |
| CDK10 | cyclin-dependent kinase 10 | -0.00709422 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | -0.00709078 |
| COL1A2 | collagen, type I, alpha 2 | -0.00708965 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00708694 |
| LOXL1 | lysyl oxidase-like 1 | -0.00707507 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 | -0.00707067 |
| CLDN3 | claudin 3 | -0.00707025 |
| RANGAP1 | Ran GTPase activating protein 1 | -0.00705847 |
| FST | follistatin | -0.00703867 |
| SFN | stratifin | -0.00703865 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00703113 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00700598 |
| SDC3 | syndecan 3 | -0.00700561 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00699049 |
| FSTL1 | follistatin-like 1 | -0.00697845 |
| EXPH5 | exophilin 5 | -0.00697044 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00695714 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | -0.00694215 |
| PCP4 | Purkinje cell protein 4 | -0.006934 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00693294 |
| KRT1 | keratin 1, type II | -0.00692418 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00691564 |
| DMPK | dystrophia myotonica-protein kinase | -0.00690705 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.0068845 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00688421 |
| PTK2B | protein tyrosine kinase 2 beta | -0.0068785 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00687464 |
| H2AX | H2A.X variant histone | -0.00686575 |
| FLNC | filamin C, gamma | -0.00686258 |
| RNF43 | ring finger protein 43 | -0.00686117 |
| NSUN5 | NOP2/Sun domain family, member 5 | -0.00685956 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00685328 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) | -0.00683858 |
| CTSK | cathepsin K | -0.00683691 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.00682828 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00682121 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00681617 |
| MPC2 | mitochondrial pyruvate carrier 2 | -0.00680996 |
| TMEM164 | transmembrane protein 164 | -0.00678936 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00678593 |
| NISCH | nischarin | -0.00677311 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00675866 |
| ATP5F1D | ATP synthase F1 subunit delta | -0.00675142 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00674733 |
| PMM1 | phosphomannomutase 1 | -0.00673205 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00672549 |
| HMGB1 | high mobility group box 1 | -0.00671476 |
| DES | desmin | -0.0066932 |
| MAGED1 | melanoma antigen family D1 | -0.00668657 |
| RRAGA | Ras-related GTP binding A | -0.00668514 |
| COL3A1 | collagen, type III, alpha 1 | -0.00668186 |
| RTN3 | reticulon 3 | -0.0066768 |
| GPSM2 | G-protein signaling modulator 2 | -0.00667278 |
| TMEM176B | transmembrane protein 176B | -0.00665787 |
| CIDEA | cell death-inducing DFFA-like effector a | -0.00664236 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -0.00664216 |
| PHGDH | phosphoglycerate dehydrogenase | -0.00663273 |
| H1-0 | H1.0 linker histone | -0.00661924 |
| VARS | valyl-tRNA synthetase | -0.0066062 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00658806 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00657888 |
| PFKL | phosphofructokinase, liver | -0.00657532 |
| CAMP | cathelicidin antimicrobial peptide | -0.00655152 |
| ZNF329 | zinc finger protein 329 | -0.00654935 |
| FAM117A | family with sequence similarity 117, member A | -0.00653328 |
