| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cyclin D3|The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] (NCBI Entrez Gene Database, 896) |
| External Link | https://ncbi.nlm.nih.gov/gene/896 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the CCND3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | 0.00967705 |
| BEX1 | brain expressed, X-linked 1 | 0.00827199 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00726928 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00704787 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.0069103 |
| SYNM | synemin, intermediate filament protein | 0.00677003 |
| ADIRF | adipogenesis regulatory factor | 0.00676034 |
| COL5A2 | collagen, type V, alpha 2 | 0.00637033 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00589036 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00587848 |
| S100A8 | S100 calcium binding protein A8 | 0.00568328 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00547716 |
| TPM2 | tropomyosin 2 (beta) | 0.00540365 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0052433 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.00522077 |
| PRNP | prion protein | 0.00517737 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00512778 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00507878 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00505058 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00500153 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00499869 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00497041 |
| S100A7 | S100 calcium binding protein A7 | 0.00496236 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0049235 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00487204 |
| SPRR3 | small proline-rich protein 3 | 0.00487166 |
| GM2A | GM2 ganglioside activator | 0.00486747 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00483663 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.00481836 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00473897 |
| NLGN4X | neuroligin 4, X-linked | 0.0047095 |
| REG1A | regenerating islet-derived 1 alpha | 0.00468119 |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.00463311 |
| GPR137B | G protein-coupled receptor 137B | 0.0046258 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00461372 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.00457162 |
| IL1RN | interleukin 1 receptor antagonist | 0.00455989 |
| FABP7 | fatty acid binding protein 7, brain | 0.00455281 |
| DENND2D | DENN/MADD domain containing 2D | 0.00448952 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00444246 |
| SIRPA | signal-regulatory protein alpha | 0.00444063 |
| CCND2 | cyclin D2 | 0.00437855 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00437463 |
| ABHD6 | abhydrolase domain containing 6 | 0.00428394 |
| RNASET2 | ribonuclease T2 | 0.00427098 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00426828 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00426244 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00417706 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.00417451 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00416677 |
| MMP1 | matrix metallopeptidase 1 | 0.00414293 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 0.00412258 |
| HMOX1 | heme oxygenase 1 | 0.00409836 |
| STK10 | serine/threonine kinase 10 | 0.0040852 |
| CRYAB | crystallin, alpha B | 0.00405081 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.00403543 |
| TMEM255A | transmembrane protein 255A | 0.00401811 |
| SPP1 | secreted phosphoprotein 1 | 0.00398081 |
| PTN | pleiotrophin | 0.00396968 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0039667 |
| PLS3 | plastin 3 | 0.00394421 |
| PLA1A | phospholipase A1 member A | 0.00392987 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00391248 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00388908 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00387952 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00386734 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00385942 |
| PTHLH | parathyroid hormone-like hormone | 0.00385019 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00384834 |
| RUNX3 | runt-related transcription factor 3 | 0.00384412 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.00383017 |
| FNBP1 | formin binding protein 1 | 0.00380404 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 0.00379855 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00378316 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00377972 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00376471 |
| VCL | vinculin | 0.00375544 |
| NLRP2 | NLR family, pyrin domain containing 2 | 0.00371695 |
| ANXA2 | annexin A2 | 0.00371239 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00369818 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00369121 |
| ITGA6 | integrin, alpha 6 | 0.00367804 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00366945 |
| MID1 | midline 1 | 0.00365251 |
| MAOB | monoamine oxidase B | 0.00364705 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 0.00363517 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 0.00362245 |
| PRDX2 | peroxiredoxin 2 | 0.00360981 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00360619 |
| TSPAN3 | tetraspanin 3 | 0.0035931 |
| TUBB6 | tubulin, beta 6 class V | 0.00355828 |
| MCAM | melanoma cell adhesion molecule | 0.00352657 |
| CTSB | cathepsin B | 0.00352484 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00352442 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00352277 |
| HK2 | hexokinase 2 | 0.00351976 |
| DEFB1 | defensin, beta 1 | 0.00351376 |
| MATN2 | matrilin 2 | 0.00349172 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00348692 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00347307 |
| MMP12 | matrix metallopeptidase 12 | 0.00346475 |
| TP63 | tumor protein p63 | 0.00345079 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00344867 |
| SP110 | SP110 nuclear body protein | 0.00344349 |
| NKG7 | natural killer cell granule protein 7 | 0.0034336 |
| IGF1R | insulin-like growth factor 1 receptor | 0.00342758 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00340735 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.00338962 |
| GSR | glutathione reductase | 0.00338448 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.0033842 |
| CD44 | CD44 molecule (Indian blood group) | 0.00337527 |
| LAMA4 | laminin, alpha 4 | 0.00337242 |
| GPX2 | glutathione peroxidase 2 | 0.00337152 |
| RCAN1 | regulator of calcineurin 1 | 0.00336187 |
| CFD | complement factor D (adipsin) | 0.00336153 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00335821 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00335653 |
| PLXNA1 | plexin A1 | 0.00335508 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00332557 |
| ATP10B | ATPase, class V, type 10B | 0.0033248 |
| GOLGA8A | golgin A8 family, member A | 0.00332263 |
| S100A10 | S100 calcium binding protein A10 | 0.00331945 |
| CTTN | cortactin | 0.00331574 |
| GLDC | glycine dehydrogenase (decarboxylating) | 0.00330998 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00330837 |
| PRSS3 | protease, serine, 3 | 0.00330737 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.00330572 |
| CALCA | calcitonin-related polypeptide alpha | 0.00329055 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | 0.00328377 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.00328295 |
| ZNF532 | zinc finger protein 532 | 0.00327659 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00326877 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.00326307 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0032625 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00326041 |
| KIAA0930 | KIAA0930 | 0.00325638 |
| CTSH | cathepsin H | 0.00325277 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00325226 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00324617 |
| CSTA | cystatin A (stefin A) | 0.00323507 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00323014 |
| CNN1 | calponin 1, basic, smooth muscle | 0.00322531 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.00322152 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00320709 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00320139 |
| SLC25A12 | solute carrier family 25 (aspartate/glutamate carrier), member 12 | 0.00320034 |
| UBE3C | ubiquitin protein ligase E3C | 0.00319908 |
| FHL1 | four and a half LIM domains 1 | 0.00319416 |
| MX2 | MX dynamin-like GTPase 2 | 0.00318198 |
| TGFA | transforming growth factor, alpha | 0.00317071 |
| TLR4 | toll-like receptor 4 | 0.00316042 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00316039 |
| WFS1 | Wolfram syndrome 1 (wolframin) | 0.00315288 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00314484 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 0.00314113 |
| BCHE | butyrylcholinesterase | 0.00314013 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00313894 |
| UBFD1 | ubiquitin family domain containing 1 | 0.00312263 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00312163 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00311509 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.00311308 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | 0.00311045 |
| COL1A2 | collagen, type I, alpha 2 | 0.00310855 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.00310411 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00310312 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.00310232 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00310031 |
| S100A9 | S100 calcium binding protein A9 | 0.00309973 |
| ARHGAP17 | Rho GTPase activating protein 17 | 0.0030937 |
| MAGEA3 | melanoma antigen family A3 | 0.00309307 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00309238 |
| ITGAV | integrin, alpha V | 0.0030923 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 0.00309039 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00308519 |
| ACLY | ATP citrate lyase | 0.00308282 |
| FAM198B | family with sequence similarity 198, member B | 0.00307375 |
| ACOT7 | acyl-CoA thioesterase 7 | 0.00307157 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.00306018 |
| SYT1 | synaptotagmin I | 0.00305418 |
| TSPO | translocator protein (18kDa) | 0.0030512 |
| EGR2 | early growth response 2 | 0.00304353 |
| MCC | mutated in colorectal cancers | 0.00303833 |
| GNLY | granulysin | 0.00303737 |
| RPL36 | ribosomal protein L36 | 0.00303646 |
| CA12 | carbonic anhydrase XII | 0.00303465 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00303309 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.00302639 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.00302309 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00301319 |
| TFRC | transferrin receptor | 0.00301311 |
| PLXNC1 | plexin C1 | 0.00301265 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00301237 |
| NDUFS2 | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 0.00300063 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00299536 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00299431 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.0029931 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00298654 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00297939 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00296291 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | 0.00295641 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00295527 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00295516 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00294923 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00294643 |
| DOCK10 | dedicator of cytokinesis 10 | 0.00294566 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00294489 |
| A2M | alpha-2-macroglobulin | 0.00294429 |
| GSDME | gasdermin E | 0.00293709 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.00292414 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.00292276 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | 0.00291046 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00290153 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00289322 |
| TENM1 | teneurin transmembrane protein 1 | 0.00288988 |
| SPRR2B | small proline-rich protein 2B | 0.00288946 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00288855 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.00287938 |
| CD99 | CD99 molecule | 0.00287483 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00287389 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00287318 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | 0.00286917 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00286788 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00286294 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00285365 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00285253 |
| UPK1A | uroplakin 1A | 0.00284931 |
| TRIM22 | tripartite motif containing 22 | 0.00284734 |
| AK4 | adenylate kinase 4 | 0.00284658 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.00284478 |
| EGR3 | early growth response 3 | 0.00283859 |
| IL1B | interleukin 1, beta | 0.00283452 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 | 0.00282067 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.00282021 |
| IFI44L | interferon-induced protein 44-like | 0.00281386 |
| CD200 | CD200 molecule | 0.00281337 |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.00280952 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00279967 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00279322 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00279138 |
| TCTA | T-cell leukemia translocation altered | 0.00278888 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.00278453 |
| LPIN1 | lipin 1 | 0.00277861 |
| TMEM140 | transmembrane protein 140 | 0.00277778 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00277681 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.00277245 |
| POPDC3 | popeye domain containing 3 | 0.002767 |
| LOXL2 | lysyl oxidase-like 2 | 0.00276675 |
| PRF1 | perforin 1 (pore forming protein) | 0.00276234 |
| CYBB | cytochrome b-245, beta polypeptide | 0.00275883 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.00275603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCND3 | cyclin D3 | -0.0100982 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00743315 |
| RPA3 | replication protein A3, 14kDa | -0.00721186 |
| LTF | lactotransferrin | -0.00675441 |
| CENPU | centromere protein U | -0.00636386 |
| ANXA3 | annexin A3 | -0.00635003 |
| NPY | neuropeptide Y | -0.00603224 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00595387 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00595338 |
| C7 | complement component 7 | -0.0054129 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00536181 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00535773 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00533103 |
| RGCC | regulator of cell cycle | -0.00531865 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00520298 |
| HMGB2 | high mobility group box 2 | -0.00518479 |
| CDC45 | cell division cycle 45 | -0.00494688 |
| MT1M | metallothionein 1M | -0.00491266 |
| TMSB15A | thymosin beta 15a | -0.00485324 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0048231 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00477658 |
| H2AFV | H2A histone family, member V | -0.00475696 |
| DEK | DEK proto-oncogene | -0.0046015 |
| H1-10 | H1.10 linker histone | -0.00459455 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00456124 |
| KLHDC3 | kelch domain containing 3 | -0.00450516 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00446348 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00444682 |
| PCNA | proliferating cell nuclear antigen | -0.00438961 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00437848 |
| DCK | deoxycytidine kinase | -0.0043753 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00431923 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00427086 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00415682 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00411398 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | -0.00410784 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00408669 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00407845 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | -0.00406092 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.00404435 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00404424 |
| USP1 | ubiquitin specific peptidase 1 | -0.00403696 |
| MAP7 | microtubule-associated protein 7 | -0.00398694 |
| CD1E | CD1e molecule | -0.00397787 |
| ATF1 | activating transcription factor 1 | -0.00392068 |
| GUK1 | guanylate kinase 1 | -0.00391731 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00386307 |
| GLO1 | glyoxalase I | -0.00383605 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00382333 |
| PROM1 | prominin 1 | -0.00381243 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | -0.00378798 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0037864 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00375332 |
| KIF20A | kinesin family member 20A | -0.00373126 |
| TMEM14B | transmembrane protein 14B | -0.00371985 |
| CD2AP | CD2-associated protein | -0.00371567 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00369617 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00368929 |
| PHYH | phytanoyl-CoA 2-hydroxylase | -0.00367603 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00366919 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.00366852 |
| KLHL2 | kelch-like family member 2 | -0.00365733 |
| KYNU | kynureninase | -0.00365486 |
| SEPHS1 | selenophosphate synthetase 1 | -0.00364606 |
| GPR88 | G protein-coupled receptor 88 | -0.00363512 |
| PON1 | paraoxonase 1 | -0.00363301 |
| SUMO3 | small ubiquitin-like modifier 3 | -0.00363172 |
| BRD2 | bromodomain containing 2 | -0.00362857 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00362678 |
| KRT7 | keratin 7, type II | -0.00362437 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00358692 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00358558 |
| FMO3 | flavin containing monooxygenase 3 | -0.0035652 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00356399 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00355889 |
| H2AX | H2A.X variant histone | -0.00354433 |
| DBF4 | DBF4 zinc finger | -0.00353434 |
| APOA2 | apolipoprotein A-II | -0.00353213 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00352561 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | -0.00350738 |
| HP | haptoglobin | -0.00348226 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00347374 |
| PLPP3 | phospholipid phosphatase 3 | -0.0034721 |
| STMN1 | stathmin 1 | -0.0034599 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00345986 |
| SAC3D1 | SAC3 domain containing 1 | -0.0034511 |
| CHKB | choline kinase beta | -0.00344983 |
| MED20 | mediator complex subunit 20 | -0.00344546 |
| COMP | cartilage oligomeric matrix protein | -0.00344522 |
| TRMT5 | tRNA methyltransferase 5 | -0.00343815 |
| TMPO | thymopoietin | -0.00343781 |
| KIF14 | kinesin family member 14 | -0.00343676 |
| NFE2 | nuclear factor, erythroid 2 | -0.00342715 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00339797 |
| TYMS | thymidylate synthetase | -0.00339446 |
| CCNA2 | cyclin A2 | -0.00338818 |
| PTTG1 | pituitary tumor-transforming 1 | -0.00337572 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00336698 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00335878 |
| RTN2 | reticulon 2 | -0.00335374 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | -0.00334921 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00334132 |
| EPCAM | epithelial cell adhesion molecule | -0.00333691 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0033189 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00331525 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00330893 |
| CCNB2 | cyclin B2 | -0.00330623 |
| ANGEL2 | angel homolog 2 (Drosophila) | -0.00328758 |
| GCHFR | GTP cyclohydrolase I feedback regulator | -0.00328488 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 | -0.00328474 |
| GPX4 | glutathione peroxidase 4 | -0.00325782 |
| SIVA1 | SIVA1, apoptosis-inducing factor | -0.00324723 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00324703 |
| AEBP1 | AE binding protein 1 | -0.0032468 |
| CDA | cytidine deaminase | -0.00324633 |
| CRY1 | cryptochrome circadian clock 1 | -0.00323306 |
| NKX3-1 | NK3 homeobox 1 | -0.00322174 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00320416 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00320098 |
| MACROH2A1 | macroH2A.1 histone | -0.00319454 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | -0.00319208 |
| MTCH1 | mitochondrial carrier 1 | -0.00319202 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00318725 |
| FOXM1 | forkhead box M1 | -0.00318636 |
| CRIP2 | cysteine-rich protein 2 | -0.00318486 |
| CDC20 | cell division cycle 20 | -0.00318364 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00318164 |
| GMNN | geminin, DNA replication inhibitor | -0.00317313 |
| HMGN1 | high mobility group nucleosome binding domain 1 | -0.0031726 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00316852 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00316061 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit | -0.00314835 |
| CCNE2 | cyclin E2 | -0.00314236 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00313935 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00313067 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.00313003 |
| SIK1 | salt-inducible kinase 1 | -0.00312727 |
| MRPS10 | mitochondrial ribosomal protein S10 | -0.00312351 |
| KLF10 | Kruppel-like factor 10 | -0.0031204 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00311925 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -0.00311787 |
| TSPAN13 | tetraspanin 13 | -0.00311717 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00310514 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.00310405 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00309698 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | -0.00309559 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0030932 |
| FMO5 | flavin containing monooxygenase 5 | -0.00309238 |
| NINJ2 | ninjurin 2 | -0.00309221 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00308219 |
| PRKD3 | protein kinase D3 | -0.00308121 |
| KIF5B | kinesin family member 5B | -0.00308059 |
| BAG6 | BCL2-associated athanogene 6 | -0.00307864 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00307858 |
| HES1 | hes family bHLH transcription factor 1 | -0.00305875 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | -0.00305495 |
| RRM2 | ribonucleotide reductase M2 | -0.00304433 |
| NELFE | negative elongation factor complex member E | -0.00303627 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.00303015 |
| NXT1 | nuclear transport factor 2-like export factor 1 | -0.00299536 |
| PDE9A | phosphodiesterase 9A | -0.00298925 |
| MUC1 | mucin 1, cell surface associated | -0.00298713 |
| CCDC28A | coiled-coil domain containing 28A | -0.00298117 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00298105 |
| TMEM126B | transmembrane protein 126B | -0.00297826 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00297439 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -0.00296867 |
| PNKP | polynucleotide kinase 3'-phosphatase | -0.00296825 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00295988 |
| ASGR2 | asialoglycoprotein receptor 2 | -0.00295372 |
| NEK2 | NIMA-related kinase 2 | -0.0029522 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | -0.00294251 |
| CHMP3 | charged multivesicular body protein 3 | -0.00294216 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00293869 |
| FLOT1 | flotillin 1 | -0.0029324 |
| HBZ | hemoglobin, zeta | -0.00293006 |
| BGN | biglycan | -0.00292811 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.00292511 |
| NINL | ninein-like | -0.00292411 |
| BARD1 | BRCA1 associated RING domain 1 | -0.00290578 |
| TPD52L1 | tumor protein D52-like 1 | -0.00290045 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00289683 |
| CEP55 | centrosomal protein 55kDa | -0.00289586 |
| GUSB | glucuronidase, beta | -0.00289257 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | -0.00289164 |
| CDT1 | chromatin licensing and DNA replication factor 1 | -0.00288574 |
| RMI1 | RecQ mediated genome instability 1 | -0.00288089 |
| CMC2 | C-x(9)-C motif containing 2 | -0.00288022 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00287794 |
| KNTC1 | kinetochore associated 1 | -0.00287565 |
| RFK | riboflavin kinase | -0.00286684 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00286037 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0028591 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -0.00285399 |
| AMH | anti-Mullerian hormone | -0.00285252 |
| BCL7B | B-cell CLL/lymphoma 7B | -0.00284795 |
| DAPK1 | death-associated protein kinase 1 | -0.0028466 |
| MIS12 | MIS12 kinetochore complex component | -0.00284658 |
| GATA2 | GATA binding protein 2 | -0.00283711 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -0.00283532 |
| CLIC1 | chloride intracellular channel 1 | -0.00283146 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.00283102 |
| BPI | bactericidal/permeability-increasing protein | -0.0028291 |
| EBAG9 | estrogen receptor binding site associated, antigen, 9 | -0.00282207 |
| NOTCH1 | notch 1 | -0.00282014 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00281601 |
| EFNA1 | ephrin-A1 | -0.00281562 |
| AURKB | aurora kinase B | -0.00281352 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00280978 |
| CDCA3 | cell division cycle associated 3 | -0.002798 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.002789 |
| AMD1 | adenosylmethionine decarboxylase 1 | -0.00278558 |
| KRT19 | keratin 19, type I | -0.00277757 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00277324 |
| PER1 | period circadian clock 1 | -0.00276337 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00276067 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00275555 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.00275513 |
| INHBA | inhibin, beta A | -0.00275358 |
| DSP | desmoplakin | -0.00275165 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0027469 |
| GSE1 | Gse1 coiled-coil protein | -0.00274595 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.00274559 |
| CLDN3 | claudin 3 | -0.00274266 |
| AOX1 | aldehyde oxidase 1 | -0.00273463 |
| DHFR | dihydrofolate reductase | -0.0027334 |
| NUP54 | nucleoporin 54kDa | -0.00273287 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.00273124 |
| LRRC15 | leucine rich repeat containing 15 | -0.00272703 |
| TAF11 | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa | -0.0027262 |
| KRT8 | keratin 8, type II | -0.00272275 |
| COLEC11 | collectin sub-family member 11 | -0.00272212 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | -0.00272028 |
| TGFB1 | transforming growth factor, beta 1 | -0.00271871 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | -0.00270693 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00270299 |
| CAPN1 | calpain 1, (mu/I) large subunit | -0.00270069 |
| RAD21 | RAD21 homolog (S. pombe) | -0.00270015 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | -0.00269803 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00269798 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00269721 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00269554 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.00269333 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.00269036 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00268907 |
| EREG | epiregulin | -0.00268866 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | -0.00268808 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 | -0.00268422 |
| ELN | elastin | -0.00268326 |
