| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cyclin E1|The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 898) |
| External Link | https://ncbi.nlm.nih.gov/gene/898 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the CCNE1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0129698 |
| TLR4 | toll-like receptor 4 | 0.0126143 |
| CLU | clusterin | 0.0104049 |
| CST3 | cystatin C | 0.0103611 |
| MGP | matrix Gla protein | 0.0102888 |
| KRT7 | keratin 7, type II | 0.0101507 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.0101149 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00977927 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00964265 |
| KRT19 | keratin 19, type I | 0.00947439 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00837826 |
| AOX1 | aldehyde oxidase 1 | 0.00825064 |
| TSPAN8 | tetraspanin 8 | 0.00805117 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00799593 |
| KRT18 | keratin 18, type I | 0.00799301 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00798182 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00784797 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00770344 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00759581 |
| HOXC6 | homeobox C6 | 0.00755107 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00750414 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00750394 |
| S100P | S100 calcium binding protein P | 0.00743123 |
| CFB | complement factor B | 0.00737772 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00736837 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00735811 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00727404 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00726488 |
| TRIM22 | tripartite motif containing 22 | 0.00716873 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00708084 |
| C7 | complement component 7 | 0.00703045 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00701556 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00701031 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00693465 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00683695 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00681749 |
| PALLD | palladin, cytoskeletal associated protein | 0.0067717 |
| AGR2 | anterior gradient 2 | 0.00674628 |
| CD302 | CD302 molecule | 0.00673579 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.0067151 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | 0.00669424 |
| LIPG | lipase, endothelial | 0.00664596 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00663883 |
| TGM2 | transglutaminase 2 | 0.00662854 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00656486 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00652797 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00646573 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00646122 |
| C1S | complement component 1, s subcomponent | 0.00643475 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00638085 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00634286 |
| HOPX | HOP homeobox | 0.00630615 |
| PLSCR4 | phospholipid scramblase 4 | 0.00629556 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00628612 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00624624 |
| IL18 | interleukin 18 | 0.00622499 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00621924 |
| C1R | complement component 1, r subcomponent | 0.00610276 |
| CSTA | cystatin A (stefin A) | 0.00607077 |
| PEG3 | paternally expressed 3 | 0.00604494 |
| FILIP1L | filamin A interacting protein 1-like | 0.00602911 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00601993 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00597197 |
| LHFP | lipoma HMGIC fusion partner | 0.00596783 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00590774 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00590121 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00589655 |
| METTL7A | methyltransferase like 7A | 0.00588583 |
| MSMB | microseminoprotein, beta- | 0.00585527 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.0058547 |
| MSLN | mesothelin | 0.00584764 |
| GNAS | GNAS complex locus | 0.00579974 |
| IRS2 | insulin receptor substrate 2 | 0.00579441 |
| TPD52L1 | tumor protein D52-like 1 | 0.00577863 |
| CHGB | chromogranin B | 0.00577856 |
| NOTCH2 | notch 2 | 0.00572456 |
| TSPAN13 | tetraspanin 13 | 0.00571272 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00568941 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00565024 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00561095 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00556047 |
| PERP | PERP, TP53 apoptosis effector | 0.00554366 |
| PROM1 | prominin 1 | 0.00550591 |
| AHR | aryl hydrocarbon receptor | 0.00547098 |
| SYT1 | synaptotagmin I | 0.00546561 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | 0.00544011 |
| MAP7 | microtubule-associated protein 7 | 0.00543369 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00543153 |
| ASS1 | argininosuccinate synthase 1 | 0.00542286 |
| STK39 | serine threonine kinase 39 | 0.0054083 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00535851 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00523624 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 0.00522565 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | 0.00519829 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00516814 |
| C2 | complement component 2 | 0.0051543 |
| STMN2 | stathmin 2 | 0.00515134 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00514349 |
| PSCA | prostate stem cell antigen | 0.00514344 |
| CFH | complement factor H | 0.00507149 |
| CP | ceruloplasmin (ferroxidase) | 0.00505346 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00503927 |
| C3 | complement component 3 | 0.00503374 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00499252 |
| S100A11 | S100 calcium binding protein A11 | 0.0049903 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00496602 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00495003 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00492075 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00491633 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00488786 |
| RND3 | Rho family GTPase 3 | 0.00488528 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.00488495 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00487447 |
| HEBP2 | heme binding protein 2 | 0.00486057 |
| TFF1 | trefoil factor 1 | 0.00485313 |
| TGFA | transforming growth factor, alpha | 0.00484954 |
| FGF13 | fibroblast growth factor 13 | 0.00483813 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00482887 |
| THBS1 | thrombospondin 1 | 0.0048027 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00479555 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00472987 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00472607 |
| TRIM16 | tripartite motif containing 16 | 0.00469738 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00469701 |
| PSAP | prosaposin | 0.00467528 |
| ABLIM1 | actin binding LIM protein 1 | 0.00467328 |
| SSPN | sarcospan | 0.00466352 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00465822 |
| CD99 | CD99 molecule | 0.00465011 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00464977 |
| PLXNB2 | plexin B2 | 0.0046434 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00464244 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00463137 |
| RAB8A | RAB8A, member RAS oncogene family | 0.0046194 |
| MFAP5 | microfibrillar associated protein 5 | 0.00461079 |
| CORO1B | coronin, actin binding protein, 1B | 0.00460387 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00459379 |
| ACTB | actin, beta | 0.00459287 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | 0.00458089 |
| FADS3 | fatty acid desaturase 3 | 0.00458003 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.00457748 |
| HNMT | histamine N-methyltransferase | 0.00456513 |
| OSMR | oncostatin M receptor | 0.00453664 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.004519 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00451375 |
| FHL1 | four and a half LIM domains 1 | 0.00449663 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00449627 |
| NOTCH2NL | notch 2 N-terminal like | 0.00448661 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00448512 |
| MGLL | monoglyceride lipase | 0.00446959 |
| SEPTIN6 | septin 6 | 0.0044618 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.00445821 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.0044522 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00444655 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 0.00444446 |
| CAV2 | caveolin 2 | 0.00444175 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00442945 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00442591 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.00441088 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.00440295 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 0.00439962 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00439685 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00438867 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00438749 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00437736 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00437193 |
| DSE | dermatan sulfate epimerase | 0.00436927 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0043615 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.0043573 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00435233 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00432524 |
| SHTN1 | shootin 1 | 0.00431965 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00431533 |
| MVP | major vault protein | 0.00431116 |
| CTTN | cortactin | 0.00430789 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00430667 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00429288 |
| RET | ret proto-oncogene | 0.00428451 |
| AXL | AXL receptor tyrosine kinase | 0.00428285 |
| BAD | BCL2-associated agonist of cell death | 0.00426983 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00426207 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00424463 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00423865 |
| GRAMD2B | GRAM domain containing 2B | 0.00422757 |
| MTMR11 | myotubularin related protein 11 | 0.00422559 |
| ADCY9 | adenylate cyclase 9 | 0.00420461 |
| CLDN1 | claudin 1 | 0.00418438 |
| GSTK1 | glutathione S-transferase kappa 1 | 0.00416251 |
| L1CAM | L1 cell adhesion molecule | 0.00416121 |
| IQCG | IQ motif containing G | 0.00415662 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00415182 |
| TSPYL5 | TSPY-like 5 | 0.00414941 |
| MAPK13 | mitogen-activated protein kinase 13 | 0.00414678 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00413988 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00411989 |
| SOCS1 | suppressor of cytokine signaling 1 | 0.00411457 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00411272 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 0.0040962 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.00409121 |
| KRT8 | keratin 8, type II | 0.00409098 |
| PRKCZ | protein kinase C, zeta | 0.00409066 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0040881 |
| MAOA | monoamine oxidase A | 0.00408788 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00407386 |
| BEX1 | brain expressed, X-linked 1 | 0.00407234 |
| NFIB | nuclear factor I/B | 0.00404301 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00403566 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00403013 |
| RAB29 | RAB29, member RAS oncogene family | 0.00402571 |
| HLA-B | major histocompatibility complex, class I, B | 0.00402166 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | 0.00401688 |
| CFI | complement factor I | 0.00400941 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00400406 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00400122 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00399988 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 | 0.00399927 |
| REEP1 | receptor accessory protein 1 | 0.00399891 |
| RHOD | ras homolog family member D | 0.00398447 |
| CSK | c-src tyrosine kinase | 0.00398134 |
| C1RL | complement component 1, r subcomponent-like | 0.00397385 |
| ADI1 | acireductone dioxygenase 1 | 0.00397144 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00394722 |
| PCP4 | Purkinje cell protein 4 | 0.00394323 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00393192 |
| UFM1 | ubiquitin-fold modifier 1 | 0.00393185 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00393086 |
| EHF | ets homologous factor | 0.00392714 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00392694 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00391922 |
| DUSP4 | dual specificity phosphatase 4 | 0.00391803 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00390564 |
| HHEX | hematopoietically expressed homeobox | 0.00390515 |
| XAF1 | XIAP associated factor 1 | 0.00390453 |
| MEIS1 | Meis homeobox 1 | 0.00390383 |
| PXDC1 | PX domain containing 1 | 0.00390149 |
| PDGFC | platelet derived growth factor C | 0.00389728 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00389332 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.0038594 |
| MACROH2A1 | macroH2A.1 histone | 0.00385754 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00384938 |
| RAB32 | RAB32, member RAS oncogene family | 0.00384509 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00384501 |
| ANXA3 | annexin A3 | 0.0038368 |
| SAMHD1 | SAM domain and HD domain 1 | 0.00381683 |
| DUSP5 | dual specificity phosphatase 5 | 0.00381214 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00380352 |
| SNAI2 | snail family zinc finger 2 | 0.0038023 |
| CLDN4 | claudin 4 | 0.00380003 |
| ANXA10 | annexin A10 | 0.00379913 |
| ELOB | elongin B | 0.00378976 |
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | -0.0114816 |
| SIRT3 | sirtuin 3 | -0.0109958 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00938207 |
| CA12 | carbonic anhydrase XII | -0.0086123 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00730331 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00728784 |
| CALML3 | calmodulin-like 3 | -0.00721481 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00693465 |
| GPM6B | glycoprotein M6B | -0.00679672 |
| ZNF586 | zinc finger protein 586 | -0.006667 |
| AOC1 | amine oxidase, copper containing 1 | -0.00663533 |
| KRT14 | keratin 14, type I | -0.00663004 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0062141 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00618224 |
| GPER1 | G protein-coupled estrogen receptor 1 | -0.00608902 |
| PLK1 | polo-like kinase 1 | -0.00606646 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00606122 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.0059413 |
| RCAN1 | regulator of calcineurin 1 | -0.00587923 |
| HMG20B | high mobility group 20B | -0.00581834 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00575658 |
| NVL | nuclear VCP-like | -0.00574868 |
| LEFTY1 | left-right determination factor 1 | -0.00569751 |
| PRKCA | protein kinase C, alpha | -0.0056877 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00566342 |
| TBXA2R | thromboxane A2 receptor | -0.00560263 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00546236 |
| LRRC15 | leucine rich repeat containing 15 | -0.0054168 |
| CYTIP | cytohesin 1 interacting protein | -0.00538859 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.00534271 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -0.00533447 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | -0.00531929 |
| ANGPTL2 | angiopoietin-like 2 | -0.00530474 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.00530321 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00530003 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | -0.00529932 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00528213 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00527431 |
| NELL2 | NEL-like 2 (chicken) | -0.00517931 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00516675 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00514961 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0051341 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00510299 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0051006 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.00507735 |
| COCH | cochlin | -0.00504537 |
| CST7 | cystatin F (leukocystatin) | -0.00503742 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00502681 |
| CLC | Charcot-Leyden crystal galectin | -0.00502636 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00502136 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00501147 |
| THY1 | Thy-1 cell surface antigen | -0.00498808 |
| KRT1 | keratin 1, type II | -0.00498115 |
| XPO7 | exportin 7 | -0.00492662 |
| SPP1 | secreted phosphoprotein 1 | -0.00491513 |
| SPAG5 | sperm associated antigen 5 | -0.0048964 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00485712 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | -0.00481782 |
| CD48 | CD48 molecule | -0.00481308 |
| CD69 | CD69 molecule | -0.00481051 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00481021 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00479998 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00479679 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00478897 |
| NDRG1 | N-myc downstream regulated 1 | -0.00474656 |
| PRAME | preferentially expressed antigen in melanoma | -0.00473755 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0047349 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00472091 |
| CDCA4 | cell division cycle associated 4 | -0.00470281 |
| CD248 | CD248 molecule, endosialin | -0.00469567 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.00465916 |
| VEGFA | vascular endothelial growth factor A | -0.00465381 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00461261 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 | -0.00461246 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.00460382 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.00458941 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -0.00457768 |
| BCL2A1 | BCL2-related protein A1 | -0.00457363 |
| NOTCH3 | notch 3 | -0.00456269 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00455491 |
| MAST3 | microtubule associated serine/threonine kinase 3 | -0.00454958 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.004525 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00452066 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.00451771 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00449975 |
| NKG7 | natural killer cell granule protein 7 | -0.00447506 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00447352 |
| HAS2 | hyaluronan synthase 2 | -0.00445315 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.004453 |
| S100A7 | S100 calcium binding protein A7 | -0.00444375 |
| KRT5 | keratin 5, type II | -0.00440922 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00439959 |
| ANO3 | anoctamin 3 | -0.00434862 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00433249 |
| RPS5 | ribosomal protein S5 | -0.0043286 |
| MMP9 | matrix metallopeptidase 9 | -0.0043269 |
| SNX7 | sorting nexin 7 | -0.00431512 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00431127 |
| YBX3 | Y box binding protein 3 | -0.0043053 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.00429077 |
| STK10 | serine/threonine kinase 10 | -0.00426633 |
| MFSD12 | major facilitator superfamily domain containing 12 | -0.00426294 |
| CD8A | CD8a molecule | -0.00424818 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00424135 |
| CLEC5A | C-type lectin domain family 5, member A | -0.00423131 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0042216 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | -0.00421072 |
| DLX5 | distal-less homeobox 5 | -0.00420092 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00417982 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00417901 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00416926 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00416535 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -0.00416063 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00413894 |
| LOR | loricrin | -0.00410163 |
| PGAP2 | post-GPI attachment to proteins 2 | -0.00409968 |
| PMEL | premelanosome protein | -0.00403276 |
| THBD | thrombomodulin | -0.00402333 |
| GPR88 | G protein-coupled receptor 88 | -0.00401134 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | -0.00401059 |
| CPOX | coproporphyrinogen oxidase | -0.00398863 |
| PIMREG | PICALM interacting mitotic regulator | -0.00398622 |
| COL5A3 | collagen, type V, alpha 3 | -0.00398473 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00398253 |
| GDI2 | GDP dissociation inhibitor 2 | -0.00396728 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0039661 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00394946 |
| RESF1 | retroelement silencing factor 1 | -0.0039404 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.00393766 |
| GAL3ST1 | galactose-3-O-sulfotransferase 1 | -0.00393325 |
| KIF21B | kinesin family member 21B | -0.00393032 |
| DSG1 | desmoglein 1 | -0.00392719 |
| BMP2 | bone morphogenetic protein 2 | -0.00392354 |
| ANGPT2 | angiopoietin 2 | -0.00392229 |
| SRGN | serglycin | -0.00392145 |
| BTG3 | BTG family, member 3 | -0.00391011 |
| MMD | monocyte to macrophage differentiation-associated | -0.00389275 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.00388898 |
| BOP1 | block of proliferation 1 | -0.0038882 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0038859 |
| RNF144A | ring finger protein 144A | -0.00387578 |
| KIF20A | kinesin family member 20A | -0.00386272 |
| FBLN1 | fibulin 1 | -0.00385469 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00384699 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00384209 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.00382398 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00382 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00381988 |
| KLF13 | Kruppel-like factor 13 | -0.00381638 |
| RETN | resistin | -0.00380612 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | -0.00379768 |
| SLAMF7 | SLAM family member 7 | -0.00379058 |
| S100B | S100 calcium binding protein B | -0.00379015 |
| CLDN8 | claudin 8 | -0.0037821 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.0037805 |
| RLN1 | relaxin 1 | -0.00377624 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00377613 |
| NES | nestin | -0.00377314 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00376959 |
| DDN | dendrin | -0.00374959 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00374133 |
| FECH | ferrochelatase | -0.00374126 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00373763 |
| FSCN1 | fascin actin-bundling protein 1 | -0.00373349 |
| STAB1 | stabilin 1 | -0.00373321 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00372347 |
| CD177 | CD177 molecule | -0.00371654 |
| GABRA5 | gamma-aminobutyric acid (GABA) A receptor, alpha 5 | -0.00369411 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 | -0.00368527 |
| PCDHGA3 | protocadherin gamma subfamily A, 3 | -0.00368379 |
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 | -0.00368217 |
| CA4 | carbonic anhydrase IV | -0.00366589 |
| VBP1 | von Hippel-Lindau binding protein 1 | -0.00366346 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00365436 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00365271 |
| CTSG | cathepsin G | -0.00365083 |
| RUNX3 | runt-related transcription factor 3 | -0.00364109 |
| MIA | melanoma inhibitory activity | -0.00362155 |
| HSP90B2P | heat shock protein 90kDa beta (Grp94), member 2, pseudogene | -0.00361707 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.00361569 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.00361505 |
| ILF2 | interleukin enhancer binding factor 2 | -0.00360581 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00360575 |
| POU5F1P3 | POU class 5 homeobox 1 pseudogene 3 | -0.0036004 |
| PLAT | plasminogen activator, tissue | -0.00360018 |
| ZNF395 | zinc finger protein 395 | -0.00359717 |
| PLVAP | plasmalemma vesicle associated protein | -0.00359593 |
| GLO1 | glyoxalase I | -0.00359177 |
| CHEK1 | checkpoint kinase 1 | -0.00358 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00357588 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -0.00356577 |
| HSPA13 | heat shock protein 70kDa family, member 13 | -0.00356291 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00354665 |
| FOXG1 | forkhead box G1 | -0.00354237 |
| PF4 | platelet factor 4 | -0.00353838 |
| AMPD1 | adenosine monophosphate deaminase 1 | -0.00352078 |
| GDF3 | growth differentiation factor 3 | -0.00351435 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -0.00351356 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00351167 |
| PRTN3 | proteinase 3 | -0.00351095 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.00350814 |
| RPL10 | ribosomal protein L10 | -0.00350593 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.00350423 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | -0.00350089 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.00349932 |
| COL1A2 | collagen, type I, alpha 2 | -0.00349312 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa | -0.00348839 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00348569 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | -0.0034814 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00347806 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00347586 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.00346123 |
| FHOD3 | formin homology 2 domain containing 3 | -0.0034609 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00345886 |
| FBXO11 | F-box protein 11 | -0.00345604 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00345453 |
| RGCC | regulator of cell cycle | -0.00344762 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.00344573 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00344268 |
| KAT7 | K(lysine) acetyltransferase 7 | -0.00343893 |
| CHKB | choline kinase beta | -0.00342989 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00342778 |
| MATK | megakaryocyte-associated tyrosine kinase | -0.00342026 |
| REEP5 | receptor accessory protein 5 | -0.00341984 |
| PAEP | progestagen-associated endometrial protein | -0.00341649 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0034102 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00340596 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00340503 |
| EVI2A | ecotropic viral integration site 2A | -0.0034037 |
| HGD | homogentisate 1,2-dioxygenase | -0.00339461 |
| RGS20 | regulator of G-protein signaling 20 | -0.00339339 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00338347 |
| LSP1 | lymphocyte-specific protein 1 | -0.00338099 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | -0.00337431 |
| OLFML2B | olfactomedin-like 2B | -0.00336948 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00336586 |
| KIF18A | kinesin family member 18A | -0.00336022 |
| ADD3 | adducin 3 (gamma) | -0.00335743 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00335385 |
| ZBED4 | zinc finger, BED-type containing 4 | -0.00335137 |
| P2RY10 | purinergic receptor P2Y, G-protein coupled, 10 | -0.0033506 |
| TP73-AS1 | TP73 antisense RNA 1 | -0.00334984 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00334906 |
| ACP6 | acid phosphatase 6, lysophosphatidic | -0.00333711 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00333137 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -0.00332598 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | -0.00332432 |
| CDSN | corneodesmosin | -0.00332346 |
| KLF1 | Kruppel-like factor 1 (erythroid) | -0.00331825 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.00331641 |
