| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cyclin T1|This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013] (NCBI Entrez Gene Database, 904) |
| External Link | https://ncbi.nlm.nih.gov/gene/904 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the CCNT1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TLR4 | toll-like receptor 4 | 0.0168862 |
| MEF2C | myocyte enhancer factor 2C | 0.0131096 |
| TXNDC9 | thioredoxin domain containing 9 | 0.012147 |
| H1-2 | H1.2 linker histone, cluster member | 0.0118055 |
| HIST1H2AC | histone cluster 1, H2ac | 0.0110635 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0108677 |
| RGS4 | regulator of G-protein signaling 4 | 0.0108264 |
| NPY1R | neuropeptide Y receptor Y1 | 0.0107137 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.0105015 |
| BID | BH3 interacting domain death agonist | 0.0102998 |
| CDCA4 | cell division cycle associated 4 | 0.0101221 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0100281 |
| E2F2 | E2F transcription factor 2 | 0.00985011 |
| NNMT | nicotinamide N-methyltransferase | 0.00940615 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0093447 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00932817 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00932782 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.0093244 |
| LY86 | lymphocyte antigen 86 | 0.0091039 |
| POSTN | periostin, osteoblast specific factor | 0.00901832 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00888075 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00884507 |
| OXTR | oxytocin receptor | 0.00861965 |
| WT1 | Wilms tumor 1 | 0.00856773 |
| EGR3 | early growth response 3 | 0.00853341 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0083938 |
| NVL | nuclear VCP-like | 0.00836855 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00834272 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00828731 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00812831 |
| ESD | esterase D | 0.00789946 |
| LY96 | lymphocyte antigen 96 | 0.00786842 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00773981 |
| THBS1 | thrombospondin 1 | 0.00742273 |
| PITX3 | paired-like homeodomain 3 | 0.0073357 |
| CLDN3 | claudin 3 | 0.00730486 |
| DAXX | death-domain associated protein | 0.00727767 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.0072689 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00726078 |
| RGS2 | regulator of G-protein signaling 2 | 0.00715148 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.00712312 |
| GNAS | GNAS complex locus | 0.00696747 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | 0.00696107 |
| ADI1 | acireductone dioxygenase 1 | 0.00694097 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.00692788 |
| SATB2 | SATB homeobox 2 | 0.00692548 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.00688335 |
| MSLN | mesothelin | 0.00688197 |
| LIPT1 | lipoyltransferase 1 | 0.0068126 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.0067878 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00673921 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00670286 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00667487 |
| EFNB2 | ephrin-B2 | 0.00665033 |
| WDR61 | WD repeat domain 61 | 0.00660182 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00659844 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00657725 |
| LRRC17 | leucine rich repeat containing 17 | 0.00654774 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00654124 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00653701 |
| HIST1H2BH | histone cluster 1, H2bh | 0.00652583 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00650342 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 0.00642681 |
| GTF3A | general transcription factor IIIA | 0.00642219 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00638689 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00638238 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00627432 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00624737 |
| CHPT1 | choline phosphotransferase 1 | 0.00620697 |
| PODXL | podocalyxin-like | 0.00620303 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00619318 |
| HMGB3 | high mobility group box 3 | 0.00619105 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00618764 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.0061361 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.00613145 |
| MARCKSL1 | MARCKS-like 1 | 0.00612885 |
| TSPAN12 | tetraspanin 12 | 0.00609861 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00602707 |
| LXN | latexin | 0.00602683 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00601782 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00599533 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | 0.00599149 |
| DEFB1 | defensin, beta 1 | 0.005982 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00597962 |
| SRGN | serglycin | 0.005972 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00593977 |
| CCN2 | cellular communication network factor 2 | 0.00593912 |
| PAEP | progestagen-associated endometrial protein | 0.0059331 |
| TMEM14B | transmembrane protein 14B | 0.00591242 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00590876 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00589921 |
| HPCAL1 | hippocalcin-like 1 | 0.00588001 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00586302 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | 0.00582843 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00579252 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00575747 |
| RB1 | retinoblastoma 1 | 0.00575428 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | 0.00575351 |
| LIF | leukemia inhibitory factor | 0.00575252 |
| SURF1 | surfeit 1 | 0.0057245 |
| NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | 0.00570042 |
| ODC1 | ornithine decarboxylase 1 | 0.00566354 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 0.00565572 |
| FBXO11 | F-box protein 11 | 0.00563523 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00563079 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00558564 |
| ESR1 | estrogen receptor 1 | 0.00558368 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00558281 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00557486 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00555172 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00551626 |
| EPHB2 | EPH receptor B2 | 0.00551546 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0055114 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00549827 |
| CHMP2A | charged multivesicular body protein 2A | 0.00549375 |
| CA12 | carbonic anhydrase XII | 0.00546609 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.00546568 |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 0.00546236 |
| AREG | amphiregulin | 0.00545823 |
| ATP5F1C | ATP synthase F1 subunit gamma | 0.00545466 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.00545268 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00544169 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.00542633 |
| ANTXR1 | anthrax toxin receptor 1 | 0.00538082 |
| HSBP1 | heat shock factor binding protein 1 | 0.00537068 |
| RBM47 | RNA binding motif protein 47 | 0.00535697 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.00535638 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00535551 |
| ZNF217 | zinc finger protein 217 | 0.00533911 |
| SLC38A4 | solute carrier family 38, member 4 | 0.00533431 |
| AQP4 | aquaporin 4 | 0.00530927 |
| CCNF | cyclin F | 0.0053066 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00530374 |
| MRPS31 | mitochondrial ribosomal protein S31 | 0.00529846 |
| TSNAX | translin-associated factor X | 0.00529173 |
| PDZK1 | PDZ domain containing 1 | 0.00524853 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00520648 |
| RPS5 | ribosomal protein S5 | 0.00519904 |
| LRRC19 | leucine rich repeat containing 19 | 0.00519267 |
| CST6 | cystatin E/M | 0.00518532 |
| CYRIA | CYFIP related Rac1 interactor A | 0.00516834 |
| COX5B | cytochrome c oxidase subunit Vb | 0.0051412 |
| FOLR1 | folate receptor 1 (adult) | 0.00512964 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.00512553 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00511196 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.00510879 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 0.00510301 |
| CD1D | CD1d molecule | 0.00509499 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00507414 |
| PLAT | plasminogen activator, tissue | 0.00507326 |
| FECH | ferrochelatase | 0.00506595 |
| XK | X-linked Kx blood group | 0.00506457 |
| MSRB2 | methionine sulfoxide reductase B2 | 0.00505935 |
| LEFTY1 | left-right determination factor 1 | 0.00505164 |
| GSPT2 | G1 to S phase transition 2 | 0.00504485 |
| CLDN8 | claudin 8 | 0.00503736 |
| CCDC6 | coiled-coil domain containing 6 | 0.00503107 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00503055 |
| SUMO3 | small ubiquitin-like modifier 3 | 0.00502299 |
| TDRD3 | tudor domain containing 3 | 0.00502223 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00500534 |
| ZNF586 | zinc finger protein 586 | 0.00500243 |
| PLK1 | polo-like kinase 1 | 0.00500155 |
| MAT2B | methionine adenosyltransferase II, beta | 0.0049985 |
| WASHC4 | WASH complex subunit 4 | 0.00499397 |
| LSM1 | LSM1, U6 small nuclear RNA associated | 0.00498684 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00497992 |
| DALRD3 | DALR anticodon binding domain containing 3 | 0.0049782 |
| G6PC | glucose-6-phosphatase, catalytic subunit | 0.00497655 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00497638 |
| NOX1 | NADPH oxidase 1 | 0.00496424 |
| ATP5MJ | ATP synthase membrane subunit j | 0.00494647 |
| NPR3 | natriuretic peptide receptor 3 | 0.00494547 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) | 0.00494134 |
| MED7 | mediator complex subunit 7 | 0.00493496 |
| COQ2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase | 0.00490817 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.00490231 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00490066 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 | 0.0048977 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | 0.00488517 |
| BARD1 | BRCA1 associated RING domain 1 | 0.00487786 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00487139 |
| PPT1 | palmitoyl-protein thioesterase 1 | 0.00487086 |
| NSL1 | NSL1, MIS12 kinetochore complex component | 0.00483646 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00483397 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | 0.0048175 |
| CD86 | CD86 molecule | 0.00481677 |
| SRI | sorcin | 0.00481565 |
| COL10A1 | collagen, type X, alpha 1 | 0.00480895 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0048034 |
| CYBRD1 | cytochrome b reductase 1 | 0.0048023 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00479573 |
| VIM | vimentin | 0.00479412 |
| TEX30 | testis expressed 30 | 0.00479036 |
| GMFB | glia maturation factor, beta | 0.00478307 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.0047825 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | 0.0047744 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 0.00477011 |
| ERLIN2 | ER lipid raft associated 2 | 0.00476452 |
| NPC2 | Niemann-Pick disease, type C2 | 0.00475906 |
| IER5 | immediate early response 5 | 0.00475205 |
| SLC2A4RG | SLC2A4 regulator | 0.00473961 |
| LRRC2 | leucine rich repeat containing 2 | 0.00472627 |
| CLEC7A | C-type lectin domain family 7, member A | 0.00472385 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 | 0.0047086 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00469497 |
| MCTS1 | malignant T cell amplified sequence 1 | 0.00469067 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00467499 |
| SCEL | sciellin | 0.00467441 |
| H1-3 | H1.3 linker histone, cluster member | 0.00467007 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00466852 |
| MIS18BP1 | MIS18 binding protein 1 | 0.00466645 |
| MAP3K7CL | MAP3K7 C-terminal like | 0.00466162 |
| SRR | serine racemase | 0.00466128 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00464434 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00463981 |
| TMEM185B | transmembrane protein 185B | 0.00463168 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00462499 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00462206 |
| TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.00460763 |
| ABHD11 | abhydrolase domain containing 11 | 0.00460678 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.00460163 |
| VPREB1 | pre-B lymphocyte 1 | 0.00459956 |
| GSTO1 | glutathione S-transferase omega 1 | 0.0045905 |
| GLRX5 | glutaredoxin 5 | 0.00458798 |
| KIAA0226L | KIAA0226-like | 0.00458632 |
| RNASET2 | ribonuclease T2 | 0.00456749 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.00455058 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00454835 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | 0.00454484 |
| TFPT | TCF3 (E2A) fusion partner (in childhood Leukemia) | 0.00454457 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) | 0.00454089 |
| KLK7 | kallikrein-related peptidase 7 | 0.00453855 |
| MOAP1 | modulator of apoptosis 1 | 0.00453733 |
| HIST3H2A | histone cluster 3, H2a | 0.00453722 |
| ZNF329 | zinc finger protein 329 | 0.00453547 |
| COX15 | cytochrome c oxidase assembly homolog 15 (yeast) | 0.00453142 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.00452582 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.0045115 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | 0.00451124 |
| TCTA | T-cell leukemia translocation altered | 0.00448001 |
| SALL1 | spalt-like transcription factor 1 | 0.00447664 |
| CCL23 | chemokine (C-C motif) ligand 23 | 0.00447466 |
| PFDN4 | prefoldin subunit 4 | 0.00447343 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.00446969 |
| RWDD2B | RWD domain containing 2B | 0.00446054 |
| CHMP4A | charged multivesicular body protein 4A | 0.00446043 |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) | 0.00445959 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.00444185 |
| SEC11A | SEC11 homolog A (S. cerevisiae) | 0.00444059 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0168239 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.0130115 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0109061 |
| GPX2 | glutathione peroxidase 2 | -0.0105422 |
| MMP2 | matrix metallopeptidase 2 | -0.0104787 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0102656 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0101613 |
| LTF | lactotransferrin | -0.0100783 |
| MMP7 | matrix metallopeptidase 7 | -0.0099385 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0098758 |
| H1-0 | H1.0 linker histone | -0.00986519 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00980393 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00947671 |
| GPM6B | glycoprotein M6B | -0.00944655 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00941186 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00915506 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00915286 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00906137 |
| CES1 | carboxylesterase 1 | -0.00883021 |
| COQ8A | coenzyme Q8A | -0.00881192 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0087835 |
| PMM2 | phosphomannomutase 2 | -0.00876959 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00851573 |
| NXN | nucleoredoxin | -0.00847379 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00838042 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00834891 |
| LYZ | lysozyme | -0.00834606 |
| CA2 | carbonic anhydrase II | -0.00824187 |
| APOD | apolipoprotein D | -0.00813673 |
| CTSZ | cathepsin Z | -0.00804827 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00802736 |
| MX1 | MX dynamin-like GTPase 1 | -0.00800694 |
| DPT | dermatopontin | -0.00800616 |
| ABLIM1 | actin binding LIM protein 1 | -0.00798771 |
| INA | internexin neuronal intermediate filament protein, alpha | -0.00797467 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00796862 |
| FBLN1 | fibulin 1 | -0.00795076 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | -0.00789446 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00787004 |
| PRF1 | perforin 1 (pore forming protein) | -0.00785003 |
| SERINC5 | serine incorporator 5 | -0.00777786 |
| MYO5C | myosin VC | -0.00770947 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00770915 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00767604 |
| LIMA1 | LIM domain and actin binding 1 | -0.00764473 |
| CCDC86 | coiled-coil domain containing 86 | -0.00760659 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00758642 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00758081 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00755598 |
| TFF2 | trefoil factor 2 | -0.00754608 |
| MFAP2 | microfibrillar-associated protein 2 | -0.0075295 |
| CADM1 | cell adhesion molecule 1 | -0.00749227 |
| TOX3 | TOX high mobility group box family member 3 | -0.00742795 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00741951 |
| AGR2 | anterior gradient 2 | -0.00741942 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00741718 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00735909 |
| TP63 | tumor protein p63 | -0.00732823 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.00732343 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00730772 |
| ITGA6 | integrin, alpha 6 | -0.00726053 |
| MYRF | myelin regulatory factor | -0.0072595 |
| S100A8 | S100 calcium binding protein A8 | -0.00725436 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.00723161 |
| PCP4 | Purkinje cell protein 4 | -0.00722441 |
| GPC3 | glypican 3 | -0.00720568 |
| GNLY | granulysin | -0.00717085 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00716459 |
| SDC2 | syndecan 2 | -0.00712478 |
| BEX1 | brain expressed, X-linked 1 | -0.00710057 |
| HYOU1 | hypoxia up-regulated 1 | -0.00709702 |
| NRCAM | neuronal cell adhesion molecule | -0.00708831 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.00708065 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00706089 |
| SCGN | secretagogin, EF-hand calcium binding protein | -0.00704614 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.00702109 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00700179 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00699749 |
| ELN | elastin | -0.00689549 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00688484 |
| NDRG1 | N-myc downstream regulated 1 | -0.00687838 |
| PAX6 | paired box 6 | -0.00687737 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00686049 |
| IFI44L | interferon-induced protein 44-like | -0.00685651 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.00683626 |
| MEIS2 | Meis homeobox 2 | -0.00682528 |
| ADIPOR2 | adiponectin receptor 2 | -0.00682519 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00682505 |
| GLUL | glutamate-ammonia ligase | -0.0067863 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00677258 |
| HOXC6 | homeobox C6 | -0.00673834 |
| ASPN | asporin | -0.00664117 |
| OAT | ornithine aminotransferase | -0.0066248 |
| G0S2 | G0/G1 switch 2 | -0.00658496 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.00657535 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00657007 |
| A2M | alpha-2-macroglobulin | -0.00654673 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.00653379 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00652063 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00651984 |
| CHRDL1 | chordin-like 1 | -0.00648745 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00645723 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00644634 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.00642595 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00641344 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00640484 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00640012 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00638855 |
| ITGB4 | integrin, beta 4 | -0.00636194 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00633728 |
| PRPF8 | pre-mRNA processing factor 8 | -0.00632852 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | -0.00631624 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00625593 |
| CIDEC | cell death-inducing DFFA-like effector c | -0.00625035 |
| CARD10 | caspase recruitment domain family, member 10 | -0.00624727 |
| GSN | gelsolin | -0.00624718 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.00623537 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00622048 |
| LYST | lysosomal trafficking regulator | -0.00617345 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00617041 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -0.00616772 |
| MGP | matrix Gla protein | -0.00615744 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.0061491 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00613996 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.00613177 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00612917 |
| REG1A | regenerating islet-derived 1 alpha | -0.00612617 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00612009 |
| CDO1 | cysteine dioxygenase type 1 | -0.00611305 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.00610367 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00609759 |
| SRSF5 | serine/arginine-rich splicing factor 5 | -0.00609181 |
| CST3 | cystatin C | -0.00609175 |
| GLA | galactosidase, alpha | -0.00607658 |
| CLDN5 | claudin 5 | -0.00607104 |
| NIT1 | nitrilase 1 | -0.00606753 |
| THBS4 | thrombospondin 4 | -0.00606641 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00601168 |
| AEBP1 | AE binding protein 1 | -0.00600207 |
| ACTN1 | actinin, alpha 1 | -0.00599942 |
| CFB | complement factor B | -0.00599408 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.00598916 |
| STK10 | serine/threonine kinase 10 | -0.00598891 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.00597746 |
| ALAS1 | 5'-aminolevulinate synthase 1 | -0.0059741 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00597041 |
| TLCD3A | TLC domain containing 3A | -0.00595903 |
| MLXIP | MLX interacting protein | -0.00595635 |
| PXDN | peroxidasin | -0.0059544 |
| CPD | carboxypeptidase D | -0.00595405 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.00594647 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.00590392 |
| MSX1 | msh homeobox 1 | -0.00590316 |
| TMEM51 | transmembrane protein 51 | -0.00589591 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00589287 |
| RGCC | regulator of cell cycle | -0.00589188 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00588568 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 | -0.00587089 |
| SETBP1 | SET binding protein 1 | -0.00585608 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00584625 |
| TESC | tescalcin | -0.00584225 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | -0.00583748 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00579596 |
| RTN2 | reticulon 2 | -0.00578965 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00578388 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 | -0.00577712 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00574616 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00572851 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00572584 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00570446 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00569834 |
| DNM3 | dynamin 3 | -0.00569382 |
| CSNK1E | casein kinase 1, epsilon | -0.00568053 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00567633 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.00566567 |
| NKG7 | natural killer cell granule protein 7 | -0.00566194 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.00566145 |
| CUX1 | cut-like homeobox 1 | -0.00563464 |
| PSCA | prostate stem cell antigen | -0.00563359 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00562176 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0056021 |
| GSDMB | gasdermin B | -0.00559997 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | -0.00559964 |
| CTSE | cathepsin E | -0.00559167 |
| RCAN2 | regulator of calcineurin 2 | -0.0055898 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | -0.00555058 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00554284 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00552428 |
| RTN1 | reticulon 1 | -0.00551732 |
| PMP22 | peripheral myelin protein 22 | -0.00548452 |
| MT1M | metallothionein 1M | -0.00546532 |
| WDTC1 | WD and tetratricopeptide repeats 1 | -0.00546448 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 | -0.00546031 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00543784 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00543538 |
| MLF2 | myeloid leukemia factor 2 | -0.00543451 |
| IL2RB | interleukin 2 receptor, beta | -0.00539598 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.00539488 |
| CD164 | CD164 molecule, sialomucin | -0.00539018 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00538716 |
| NCOA2 | nuclear receptor coactivator 2 | -0.00538184 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 | -0.00535029 |
| MARS1 | methionyl-tRNA synthetase 1 | -0.00534478 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00532616 |
| JAM3 | junctional adhesion molecule 3 | -0.00532606 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00532113 |
| FOXO3 | forkhead box O3 | -0.00530846 |
| ABHD17A | abhydrolase domain containing 17A | -0.00530556 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00530224 |
| CFD | complement factor D (adipsin) | -0.00525735 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | -0.0052535 |
| SNX7 | sorting nexin 7 | -0.00524704 |
| ACKR3 | atypical chemokine receptor 3 | -0.0052458 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0052448 |
| CD8B | CD8b molecule | -0.00524219 |
| ACD | adrenocortical dysplasia homolog (mouse) | -0.00524133 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00520298 |
| OFD1 | oral-facial-digital syndrome 1 | -0.00519949 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.00518898 |
| DGCR8 | DGCR8 microprocessor complex subunit | -0.00518514 |
| SMTN | smoothelin | -0.00518443 |
| KAZN | kazrin, periplakin interacting protein | -0.00517185 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.00516927 |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -0.00516824 |
| IL1R1 | interleukin 1 receptor, type I | -0.00516587 |
| BAX | BCL2-associated X protein | -0.00516181 |
| S100B | S100 calcium binding protein B | -0.00515627 |
| XYLT1 | xylosyltransferase I | -0.00514882 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00514692 |
| CNN3 | calponin 3, acidic | -0.00514165 |
| APOB | apolipoprotein B | -0.00513691 |
| MYLK | myosin light chain kinase | -0.00513138 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.00512464 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 | -0.00512247 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | -0.00511031 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.00510554 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00510467 |
| PLS3 | plastin 3 | -0.00510239 |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 | -0.00509832 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00509822 |
| REXO2 | RNA exonuclease 2 | -0.00509709 |
| LCN2 | lipocalin 2 | -0.005096 |
| PLLP | plasmolipin | -0.00509455 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.00508483 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.00506428 |
| UTRN | utrophin | -0.00505963 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00505667 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00505495 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00505015 |
| SUSD6 | sushi domain containing 6 | -0.00504503 |
