| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | chemokine (C-C motif) receptor 1|This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1230) |
| External Link | https://ncbi.nlm.nih.gov/gene/1230 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the CCR1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HOPX | HOP homeobox | 0.0165004 |
| MAP7 | microtubule-associated protein 7 | 0.0158328 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0143304 |
| KIAA0100 | KIAA0100 | 0.013943 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.01322 |
| WASHC4 | WASH complex subunit 4 | 0.0130076 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.011998 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.0118789 |
| NPR3 | natriuretic peptide receptor 3 | 0.0115772 |
| TFEC | transcription factor EC | 0.0115142 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0114563 |
| CLU | clusterin | 0.0113264 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.0109481 |
| TSPAN13 | tetraspanin 13 | 0.0107933 |
| SIRT3 | sirtuin 3 | 0.0103414 |
| DAPK1 | death-associated protein kinase 1 | 0.00975147 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00975063 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | 0.00973446 |
| VNN1 | vanin 1 | 0.00971255 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0095327 |
| PXDN | peroxidasin | 0.00941241 |
| PDGFC | platelet derived growth factor C | 0.00933037 |
| ANXA3 | annexin A3 | 0.00920978 |
| MYO6 | myosin VI | 0.00916137 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00913288 |
| LRP2 | low density lipoprotein receptor-related protein 2 | 0.00912985 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00903459 |
| GNAS | GNAS complex locus | 0.00893852 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00879701 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00866289 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00865803 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00861197 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.0085001 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00839284 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00836175 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00834727 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0082967 |
| SFTPC | surfactant protein C | 0.00826131 |
| ZNF589 | zinc finger protein 589 | 0.00818032 |
| AMOTL2 | angiomotin like 2 | 0.00813771 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00802243 |
| IL32 | interleukin 32 | 0.00801447 |
| TLCD3A | TLC domain containing 3A | 0.00796919 |
| STK32B | serine/threonine kinase 32B | 0.00780189 |
| SFTPB | surfactant protein B | 0.00768868 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.00753265 |
| MCL1 | myeloid cell leukemia 1 | 0.00751597 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.00748702 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.00747163 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00745511 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00743959 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00742691 |
| PSAP | prosaposin | 0.00741279 |
| CLDND1 | claudin domain containing 1 | 0.00740762 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00739216 |
| GPI | glucose-6-phosphate isomerase | 0.00738019 |
| GAB2 | GRB2-associated binding protein 2 | 0.00734434 |
| FRMD4B | FERM domain containing 4B | 0.0073267 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00731805 |
| ABHD4 | abhydrolase domain containing 4 | 0.00728342 |
| PXDC1 | PX domain containing 1 | 0.00725334 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00724155 |
| ABHD6 | abhydrolase domain containing 6 | 0.00723861 |
| CD52 | CD52 molecule | 0.007214 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00719521 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00717063 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00714963 |
| H1-0 | H1.0 linker histone | 0.00714839 |
| CDH13 | cadherin 13 | 0.00714262 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.00713389 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00711886 |
| DNTT | DNA nucleotidylexotransferase | 0.00710776 |
| JADE3 | jade family PHD finger 3 | 0.0071039 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | 0.00709538 |
| MAP3K7CL | MAP3K7 C-terminal like | 0.00708402 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | 0.00705629 |
| TYMS | thymidylate synthetase | 0.00702813 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.0070279 |
| KRT18 | keratin 18, type I | 0.00700259 |
| RPS26 | ribosomal protein S26 | 0.00691945 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.00685599 |
| HAVCR1 | hepatitis A virus cellular receptor 1 | 0.00683542 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00680719 |
| USP25 | ubiquitin specific peptidase 25 | 0.00680146 |
| SFTPD | surfactant protein D | 0.00674274 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.00673667 |
| RGS13 | regulator of G-protein signaling 13 | 0.00673368 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00671044 |
| SFTPA2 | surfactant protein A2 | 0.00666276 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00665571 |
| GPR171 | G protein-coupled receptor 171 | 0.00662904 |
| LY96 | lymphocyte antigen 96 | 0.00661207 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00661133 |
| CAVIN2 | caveolae associated protein 2 | 0.00661091 |
| XIC | X chromosome inactivation center | 0.00650776 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.00650518 |
| RNF146 | ring finger protein 146 | 0.00647818 |
| PFKP | phosphofructokinase, platelet | 0.00647803 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 0.00642067 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00639864 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00639297 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00638032 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00637959 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.00637453 |
| ZNF83 | zinc finger protein 83 | 0.00636815 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.00636278 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00634766 |
| ZNF267 | zinc finger protein 267 | 0.0063393 |
| ZNHIT3 | zinc finger, HIT-type containing 3 | 0.00630347 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00629501 |
| TRAF4 | TNF receptor-associated factor 4 | 0.00624184 |
| CHIT1 | chitinase 1 (chitotriosidase) | 0.00621373 |
| COL2A1 | collagen, type II, alpha 1 | 0.00618005 |
| KIAA0125 | KIAA0125 | 0.00614269 |
| COL10A1 | collagen, type X, alpha 1 | 0.00613556 |
| BMP2 | bone morphogenetic protein 2 | 0.00609979 |
| SELL | selectin L | 0.00609303 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00608679 |
| CD200 | CD200 molecule | 0.00607227 |
| TCF4 | transcription factor 4 | 0.00607115 |
| CUX1 | cut-like homeobox 1 | 0.0060682 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00606524 |
| KLF3-AS1 | KLF3 antisense RNA 1 | 0.00605861 |
| MALL | mal, T-cell differentiation protein-like | 0.00604681 |
| NKX2-1 | NK2 homeobox 1 | 0.00600805 |
| CRCT1 | cysteine-rich C-terminal 1 | 0.00597873 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.00596156 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00595295 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00595174 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00595034 |
| TMPRSS11E | transmembrane protease, serine 11E | 0.00594271 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | 0.00593305 |
| DIAPH1 | diaphanous-related formin 1 | 0.005916 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0059121 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 0.0059066 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00590655 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00589701 |
| CST1 | cystatin SN | 0.00589022 |
| AIM2 | absent in melanoma 2 | 0.00587861 |
| CREBZF | CREB/ATF bZIP transcription factor | 0.00587444 |
| ERG28 | ergosterol biosynthesis 28 homolog | 0.0058464 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | 0.00583208 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00583137 |
| BCAS4 | breast carcinoma amplified sequence 4 | 0.00582254 |
| PLA2G2D | phospholipase A2, group IID | 0.00580044 |
| LPIN1 | lipin 1 | 0.00577823 |
| PRKCB | protein kinase C, beta | 0.00576288 |
| PEX3 | peroxisomal biogenesis factor 3 | 0.00575602 |
| RNF7 | ring finger protein 7 | 0.00573532 |
| STX7 | syntaxin 7 | 0.00573281 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00573017 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00572059 |
| CBX4 | chromobox homolog 4 | 0.00571789 |
| LYRM4 | LYR motif containing 4 | 0.00570978 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.00569916 |
| H1-10 | H1.10 linker histone | 0.00569596 |
| RIT1 | Ras-like without CAAX 1 | 0.00569394 |
| MMRN1 | multimerin 1 | 0.00566306 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00565917 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00565896 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.00565409 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | 0.00563501 |
| IER2 | immediate early response 2 | 0.00560812 |
| KLF6 | Kruppel-like factor 6 | 0.0056031 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00559977 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | 0.00559838 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00558349 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 | 0.00557639 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.00554415 |
| FADD | Fas (TNFRSF6)-associated via death domain | 0.00552481 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0055203 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.0055163 |
| LRRC1 | leucine rich repeat containing 1 | 0.00550485 |
| PLXND1 | plexin D1 | 0.00550163 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.00549913 |
| ZNF302 | zinc finger protein 302 | 0.00549022 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00547288 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.00541845 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.00541604 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | 0.00538326 |
| ESM1 | endothelial cell-specific molecule 1 | 0.00538194 |
| TXNIP | thioredoxin interacting protein | 0.00536819 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00536473 |
| IRF1 | interferon regulatory factor 1 | 0.00535495 |
| DENND5A | DENN/MADD domain containing 5A | 0.00533019 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like | 0.0053137 |
| ORC1 | origin recognition complex, subunit 1 | 0.00530365 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 0.00529548 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.00528524 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.0052847 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00528281 |
| RAB5A | RAB5A, member RAS oncogene family | 0.00528249 |
| MMP9 | matrix metallopeptidase 9 | 0.00528237 |
| ZNF146 | zinc finger protein 146 | 0.00526594 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00526246 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00523259 |
| ZNF281 | zinc finger protein 281 | 0.00523103 |
| DUSP14 | dual specificity phosphatase 14 | 0.00522251 |
| EDN1 | endothelin 1 | 0.00522238 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00521735 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.00521179 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00520431 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.00520316 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00519556 |
| SIRPA | signal-regulatory protein alpha | 0.00518739 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00518695 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00517412 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 | 0.00517095 |
| PDAP1 | PDGFA associated protein 1 | 0.00516356 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.00516115 |
| HPN | hepsin | 0.00515043 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.00513943 |
| CORO1C | coronin, actin binding protein, 1C | 0.00512788 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.0051261 |
| CAV2 | caveolin 2 | 0.00511878 |
| COMMD10 | COMM domain containing 10 | 0.00511452 |
| LST1 | leukocyte specific transcript 1 | 0.00511353 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 0.00510691 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | 0.00509897 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.0050819 |
| WDR1 | WD repeat domain 1 | 0.00507861 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00504885 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | 0.00504774 |
| CYRIA | CYFIP related Rac1 interactor A | 0.00503346 |
| ARMT1 | acidic residue methyltransferase 1 | 0.00503334 |
| CDC42 | cell division cycle 42 | 0.00501977 |
| NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | 0.00501941 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | 0.00500013 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00498969 |
| TFG | TRK-fused gene | 0.00498801 |
| SLC13A1 | solute carrier family 13 (sodium/sulfate symporter), member 1 | 0.0049733 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.00495578 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00495537 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00495476 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00494636 |
| RHOH | ras homolog family member H | 0.00494446 |
| UTRN | utrophin | 0.00493991 |
| CDK7 | cyclin-dependent kinase 7 | 0.00492581 |
| ZNF711 | zinc finger protein 711 | 0.00492188 |
| BDNF | brain-derived neurotrophic factor | 0.0049209 |
| ACVR1 | activin A receptor, type I | 0.00492053 |
| IRX5 | iroquois homeobox 5 | 0.00491835 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.0049023 |
| WASF1 | WAS protein family, member 1 | 0.00490163 |
| PRSS8 | protease, serine, 8 | 0.00489936 |
| ERAL1 | Era-like 12S mitochondrial rRNA chaperone 1 | 0.00489603 |
| PHB | prohibitin | 0.00487857 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00487085 |
| NKX2-2 | NK2 homeobox 2 | 0.00486706 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.00484446 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FCGBP | Fc fragment of IgG binding protein | -0.0222859 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0219227 |
| GPX2 | glutathione peroxidase 2 | -0.0168156 |
| DIPK1A | divergent protein kinase domain 1A | -0.0159495 |
| S100P | S100 calcium binding protein P | -0.0154173 |
| ASS1 | argininosuccinate synthase 1 | -0.0149684 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0148618 |
| C3 | complement component 3 | -0.0146283 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0143408 |
| A2M | alpha-2-macroglobulin | -0.0143341 |
| OLFM4 | olfactomedin 4 | -0.0142884 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.013434 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.0134157 |
| SYNM | synemin, intermediate filament protein | -0.013135 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0131296 |
| ADI1 | acireductone dioxygenase 1 | -0.0125823 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0123684 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.0122798 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0120376 |
| STC1 | stanniocalcin 1 | -0.0120018 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0118569 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0116861 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.011636 |
| LCN2 | lipocalin 2 | -0.0114881 |
| H2AFV | H2A histone family, member V | -0.0111333 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0111149 |
| MAOA | monoamine oxidase A | -0.011055 |
| PLAT | plasminogen activator, tissue | -0.0109359 |
| TMOD1 | tropomodulin 1 | -0.0109337 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0109242 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0109195 |
| FBLN1 | fibulin 1 | -0.0108513 |
| GPM6B | glycoprotein M6B | -0.0107413 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | -0.0106676 |
| AEBP1 | AE binding protein 1 | -0.0106256 |
| DES | desmin | -0.010601 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0105903 |
| CFD | complement factor D (adipsin) | -0.010474 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.0104386 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0102401 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.0102341 |
| NEFH | neurofilament, heavy polypeptide | -0.0102331 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0101312 |
| STMN2 | stathmin 2 | -0.0100782 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.0100679 |
| TRIM29 | tripartite motif containing 29 | -0.00987689 |
| SELENBP1 | selenium binding protein 1 | -0.00979782 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00971908 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00962508 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00961794 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00960937 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00956078 |
| TSPYL5 | TSPY-like 5 | -0.00953101 |
| IL1R1 | interleukin 1 receptor, type I | -0.00948565 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00947365 |
| FHOD3 | formin homology 2 domain containing 3 | -0.00939578 |
| NID2 | nidogen 2 (osteonidogen) | -0.00939328 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.00939186 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.00936847 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00915458 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00911115 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00896168 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00896005 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00895671 |
| MAPK13 | mitogen-activated protein kinase 13 | -0.00893907 |
| FABP1 | fatty acid binding protein 1, liver | -0.00891217 |
| MX1 | MX dynamin-like GTPase 1 | -0.00879742 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00875961 |
| RTN1 | reticulon 1 | -0.00874627 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00873918 |
| COLEC12 | collectin sub-family member 12 | -0.00870008 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00868579 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.00868216 |
| ZIC1 | Zic family member 1 | -0.00866505 |
| NELL2 | NEL-like 2 (chicken) | -0.00865399 |
| TGFA | transforming growth factor, alpha | -0.00861633 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00861558 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0085857 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00857199 |
| TRIB2 | tribbles pseudokinase 2 | -0.00854464 |
| RGS4 | regulator of G-protein signaling 4 | -0.0085033 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00849631 |
| TSPAN7 | tetraspanin 7 | -0.00840538 |
| RB1 | retinoblastoma 1 | -0.00838259 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00837736 |
| CNN1 | calponin 1, basic, smooth muscle | -0.0083605 |
| HOMER2 | homer scaffolding protein 2 | -0.00835245 |
| C1S | complement component 1, s subcomponent | -0.00826986 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00825753 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00824629 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00821403 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.00820877 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00819475 |
| PIR | pirin (iron-binding nuclear protein) | -0.00817802 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00817117 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00813216 |
| FRZB | frizzled-related protein | -0.00810636 |
| DCT | dopachrome tautomerase | -0.00803491 |
| CCNB1 | cyclin B1 | -0.00803361 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00800731 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00797866 |
| NPEPL1 | aminopeptidase-like 1 | -0.00796731 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00790544 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00783302 |
| ISL1 | ISL LIM homeobox 1 | -0.00782776 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00780321 |
| PTCH1 | patched 1 | -0.00779031 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00773866 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00772518 |
| PER2 | period circadian clock 2 | -0.00772336 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00772094 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.00771082 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00769828 |
| GSE1 | Gse1 coiled-coil protein | -0.00767409 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00765429 |
| PSCA | prostate stem cell antigen | -0.00759693 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00758788 |
| SDC2 | syndecan 2 | -0.00755973 |
| PEG3 | paternally expressed 3 | -0.00746557 |
| GPC1 | glypican 1 | -0.00746263 |
| MUC4 | mucin 4, cell surface associated | -0.00744512 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 | -0.00744019 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00741368 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00740033 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00739808 |
| NID1 | nidogen 1 | -0.0073943 |
| RCAN2 | regulator of calcineurin 2 | -0.00739379 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00737484 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00734525 |
| FKBP9 | FK506 binding protein 9, 63 kDa | -0.00732805 |
| PRDX2 | peroxiredoxin 2 | -0.00732615 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00730589 |
| MGP | matrix Gla protein | -0.00730387 |
| VEGFA | vascular endothelial growth factor A | -0.00726274 |
| AFP | alpha-fetoprotein | -0.00725595 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00724706 |
| REG1A | regenerating islet-derived 1 alpha | -0.00724312 |
| JAG1 | jagged 1 | -0.00724307 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00723206 |
| RRM2 | ribonucleotide reductase M2 | -0.0072277 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00721715 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.00717941 |
| XPO7 | exportin 7 | -0.00716749 |
| SERINC5 | serine incorporator 5 | -0.0071543 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00712258 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -0.00709945 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00706865 |
| PRAME | preferentially expressed antigen in melanoma | -0.00703114 |
| OLFML3 | olfactomedin-like 3 | -0.00700335 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0070013 |
| CNTN1 | contactin 1 | -0.00698636 |
| C1R | complement component 1, r subcomponent | -0.00698469 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00695707 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.00690644 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00688742 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.00688529 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00688209 |
| APOC2 | apolipoprotein C-II | -0.00686824 |
| MATN2 | matrilin 2 | -0.0068642 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.00685938 |
| CFI | complement factor I | -0.00684483 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0068375 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | -0.00682408 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00681989 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00677389 |
| TPM2 | tropomyosin 2 (beta) | -0.0067641 |
| DEFB1 | defensin, beta 1 | -0.0067497 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00674096 |
| SETBP1 | SET binding protein 1 | -0.00673905 |
| MMD | monocyte to macrophage differentiation-associated | -0.00672449 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00671861 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00671692 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00671586 |
| FLNC | filamin C, gamma | -0.00667368 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00666859 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00665949 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | -0.00665105 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00664509 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | -0.00659301 |
| MXRA5 | matrix-remodelling associated 5 | -0.00659059 |
| NRCAM | neuronal cell adhesion molecule | -0.00657507 |
| INA | internexin neuronal intermediate filament protein, alpha | -0.00657326 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00656771 |
| ZNF331 | zinc finger protein 331 | -0.00655659 |
| CD320 | CD320 molecule | -0.00655456 |
| RELN | reelin | -0.00655394 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00654456 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00653398 |
| PITX3 | paired-like homeodomain 3 | -0.0065258 |
| KRT15 | keratin 15, type I | -0.00651737 |
| MXRA8 | matrix-remodelling associated 8 | -0.00651698 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00650679 |
| GSR | glutathione reductase | -0.00649332 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.00647378 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00647374 |
| MUC16 | mucin 16, cell surface associated | -0.00646993 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00645871 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00645543 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00644727 |
| AHSG | alpha-2-HS-glycoprotein | -0.0064437 |
| ALB | albumin | -0.0064008 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00639717 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.0063893 |
| MICALL2 | MICAL-like 2 | -0.00638658 |
| PLTP | phospholipid transfer protein | -0.00638454 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00637987 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00636937 |
| PBLD | phenazine biosynthesis-like protein domain containing | -0.00636888 |
| GPR183 | G protein-coupled receptor 183 | -0.0063615 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00635649 |
| TMEM255A | transmembrane protein 255A | -0.00635447 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00634384 |
| PBK | PDZ binding kinase | -0.00633597 |
| MEN1 | multiple endocrine neoplasia I | -0.00633266 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00633195 |
| SDC1 | syndecan 1 | -0.00631397 |
| MSMB | microseminoprotein, beta- | -0.00631214 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.0063095 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0063 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.00629621 |
| THBS4 | thrombospondin 4 | -0.00628314 |
| S100B | S100 calcium binding protein B | -0.00628291 |
| PLLP | plasmolipin | -0.00628214 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | -0.00626781 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00626184 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.00625048 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00624415 |
| LRP1 | low density lipoprotein receptor-related protein 1 | -0.0062403 |
| MPC2 | mitochondrial pyruvate carrier 2 | -0.00623285 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | -0.00623179 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.00623133 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00623093 |
| VSNL1 | visinin-like 1 | -0.00622501 |
| XK | X-linked Kx blood group | -0.0062204 |
| CLCA1 | chloride channel accessory 1 | -0.00620483 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.00620115 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00619361 |
| FGL1 | fibrinogen-like 1 | -0.006161 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00615669 |
| MAB21L1 | mab-21-like 1 (C. elegans) | -0.00615036 |
| OPHN1 | oligophrenin 1 | -0.0061483 |
| SNAI2 | snail family zinc finger 2 | -0.00614634 |
| NDRG2 | NDRG family member 2 | -0.0061149 |
| SCG5 | secretogranin V | -0.00611436 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00610635 |
| MAP1B | microtubule-associated protein 1B | -0.00609845 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0060946 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00608283 |
| TDRD12 | tudor domain containing 12 | -0.00607764 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00607545 |
