CCR3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description chemokine (C-C motif) receptor 3|The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 1232)
External Link https://ncbi.nlm.nih.gov/gene/1232
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Genes

498 genes differentially expressed following the CCR3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0205678
MYBPC1 myosin binding protein C, slow type 0.0155251
HSPB1 heat shock 27kDa protein 1 0.0147202
TNNC1 troponin C type 1 (slow) 0.014243
AQP3 aquaporin 3 (Gill blood group) 0.0142367
MVP major vault protein 0.0139708
TNNT1 troponin T type 1 (skeletal, slow) 0.013826
HSPA1A heat shock 70kDa protein 1A 0.0136518
IL32 interleukin 32 0.0134894
CRYAB crystallin, alpha B 0.0123837
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0119623
STXBP2 syntaxin binding protein 2 0.0110492
TNNC2 troponin C type 2 (fast) 0.0109771
ACTA1 actin, alpha 1, skeletal muscle 0.0108903
KLHL41 kelch-like family member 41 0.0107853
CKM creatine kinase, muscle 0.0106957
ANXA3 annexin A3 0.0106153
COG7 component of oligomeric golgi complex 7 0.0102621
TTN titin 0.0101697
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.0100771
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00989195
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00982095
SLN sarcolipin 0.0097973
STATH statherin 0.00959852
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00942908
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00940875
SVIL supervillin 0.00925404
PRSS21 protease, serine, 21 (testisin) 0.00925152
TRIM16 tripartite motif containing 16 0.00924992
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00917869
EGR1 early growth response 1 0.0091778
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.00911148
SPRED2 sprouty-related, EVH1 domain containing 2 0.00910426
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.0090525
CXCL8 chemokine (C-X-C motif) ligand 8 0.00904614
TFF1 trefoil factor 1 0.00896151
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.00891393
KRT7 keratin 7, type II 0.00884133
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00878235
FOSL2 FOS-like antigen 2 0.00876853
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00873341
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.00867944
RCAN1 regulator of calcineurin 1 0.00866386
HOMER1 homer scaffolding protein 1 0.00865678
PDZK1IP1 PDZK1 interacting protein 1 0.00863452
PODXL podocalyxin-like 0.0086293
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00860581
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00844461
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00844373
PI3 peptidase inhibitor 3, skin-derived 0.00840571
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.0083763
CXCL5 chemokine (C-X-C motif) ligand 5 0.0083179
LBH limb bud and heart development 0.00831175
KYNU kynureninase 0.0082929
KRT14 keratin 14, type I 0.00822364
NEBL nebulette 0.00820749
KLK11 kallikrein-related peptidase 11 0.0081956
QPRT quinolinate phosphoribosyltransferase 0.00817381
COQ8A coenzyme Q8A 0.00810015
ZYX zyxin 0.0080682
TPM3 tropomyosin 3 0.00806489
MYOT myotilin 0.00800281
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00800076
TNNI1 troponin I type 1 (skeletal, slow) 0.00799857
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00794124
S100A7 S100 calcium binding protein A7 0.00791448
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.00789137
TSPAN8 tetraspanin 8 0.00785995
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.00784311
MSRB2 methionine sulfoxide reductase B2 0.00782545
MB myoglobin 0.0078104
BCL3 B-cell CLL/lymphoma 3 0.00779544
FOLR1 folate receptor 1 (adult) 0.00775433
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00774141
RNASET2 ribonuclease T2 0.0077208
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00760438
KRT13 keratin 13, type I 0.00759374
TBC1D4 TBC1 domain family, member 4 0.00756127
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00754869
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.00752772
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00747661
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00745665
OXTR oxytocin receptor 0.00745087
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00745044
FBXO11 F-box protein 11 0.00743268
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.0073948
ZNF185 zinc finger protein 185 (LIM domain) 0.00734411
TPM4 tropomyosin 4 0.00730456
CLTB clathrin, light chain B 0.00725091
CARMIL1 capping protein regulator and myosin 1 linker 1 0.00722014
RHCG Rh family, C glycoprotein 0.00720462
GSTP1 glutathione S-transferase pi 1 0.00720148
PENK proenkephalin 0.00717514
TWF2 twinfilin actin binding protein 2 0.0071681
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00714659
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00704397
FABP7 fatty acid binding protein 7, brain 0.00704172
MAL mal, T-cell differentiation protein 0.00704079
GMDS GDP-mannose 4,6-dehydratase 0.00703748
LY6D lymphocyte antigen 6 complex, locus D 0.00703684
RSL1D1 ribosomal L1 domain containing 1 0.00703222
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.00702575
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00701809
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00698201
NEU1 sialidase 1 (lysosomal sialidase) 0.00697706
TNNI2 troponin I type 2 (skeletal, fast) 0.00695104
JUNB jun B proto-oncogene 0.00693281
RNPS1 RNA binding protein S1, serine-rich domain 0.00686349
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00685618
CTSB cathepsin B 0.00683934
RFC2 replication factor C (activator 1) 2, 40kDa 0.00682725
NRCAM neuronal cell adhesion molecule 0.00682
CRNN cornulin 0.00677185
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.00673831
TM4SF1 transmembrane 4 L six family member 1 0.00672019
SPRR3 small proline-rich protein 3 0.00666426
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00660033
ASXL2 additional sex combs like transcriptional regulator 2 0.00658094
MARCKSL1 MARCKS-like 1 0.00657531
ACTN2 actinin, alpha 2 0.0065583
C1S complement component 1, s subcomponent 0.00655534
SCEL sciellin 0.00652579
IL1RAP interleukin 1 receptor accessory protein 0.00650769
AFTPH aftiphilin 0.00650765
MX2 MX dynamin-like GTPase 2 0.00650055
ZMAT3 zinc finger, matrin-type 3 0.00648939
FAM102A family with sequence similarity 102, member A 0.0064877
HSPH1 heat shock 105kDa/110kDa protein 1 0.0064868
FLNA filamin A, alpha 0.006475
TMED3 transmembrane emp24 protein transport domain containing 3 0.00646323
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00646225
ACAA1 acetyl-CoA acyltransferase 1 0.00641391
WWC1 WW and C2 domain containing 1 0.00640965
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00639781
UPK1B uroplakin 1B 0.0063943
TUBB2B tubulin, beta 2B class IIb 0.00638654
KRT16 keratin 16, type I 0.00638462
ALOX5 arachidonate 5-lipoxygenase 0.0063643
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.00635577
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.00635026
DSP desmoplakin 0.00633131
WASHC4 WASH complex subunit 4 0.00629717
MYOZ2 myozenin 2 0.00629444
CLIC3 chloride intracellular channel 3 0.00628773
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00628373
MT1X metallothionein 1X 0.00628146
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 0.00627099
ENO3 enolase 3 (beta, muscle) 0.00626631
ABLIM1 actin binding LIM protein 1 0.00626049
IL6ST interleukin 6 signal transducer 0.00622533
PLIN3 perilipin 3 0.00619624
CYBA cytochrome b-245, alpha polypeptide 0.0061801
AKAP8 A kinase (PRKA) anchor protein 8 0.00617767
TMPRSS4 transmembrane protease, serine 4 0.00614518
ZNF91 zinc finger protein 91 0.00612556
CRCT1 cysteine-rich C-terminal 1 0.00610876
CRIP1 cysteine-rich protein 1 (intestinal) 0.00609322
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00605202
BABAM2 BRISC and BRCA1 A complex member 2 0.0060494
LYZ lysozyme 0.00603448
CERS6 ceramide synthase 6 0.00602198
LOXL1 lysyl oxidase-like 1 0.00601763
TUFT1 tuftelin 1 0.00601573
SYNGR2 synaptogyrin 2 0.00599778
TCAP titin-cap 0.00599259
SPRR2B small proline-rich protein 2B 0.00595648
JPT1 Jupiter microtubule associated homolog 1 0.00594107
TMEM45A transmembrane protein 45A 0.00593165
RRAGD Ras-related GTP binding D 0.00593083
OXA1L oxidase (cytochrome c) assembly 1-like 0.00592975
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 0.0059267
SMPX small muscle protein, X-linked 0.00590451
OAZ1 ornithine decarboxylase antizyme 1 0.00589394
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00588826
ADAM12 ADAM metallopeptidase domain 12 0.00587777
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.00586392
FXYD3 FXYD domain containing ion transport regulator 3 0.00583486
RTN2 reticulon 2 0.00583427
BCL2A1 BCL2-related protein A1 0.0058292
OLFML3 olfactomedin-like 3 0.00581992
PEBP1 phosphatidylethanolamine binding protein 1 0.0057856
P3H2 prolyl 3-hydroxylase 2 0.0057751
RNF114 ring finger protein 114 0.0057669
C6ORF48 chromosome 6 open reading frame 48 0.00576282
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.00574857
BASP1 brain abundant, membrane attached signal protein 1 0.00574778
MED6 mediator complex subunit 6 0.00572589
R3HDM2 R3H domain containing 2 0.0057109
RPL36 ribosomal protein L36 0.00566861
TRIM29 tripartite motif containing 29 0.00566644
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00563667
SERINC3 serine incorporator 3 0.00559894
SPATA20 spermatogenesis associated 20 0.00559629
GDI2 GDP dissociation inhibitor 2 0.00558429
IER2 immediate early response 2 0.00557646
HHLA3 HERV-H LTR-associating 3 0.00555432
MAGEA12 melanoma antigen family A12 0.00555147
NIP7 NIP7, nucleolar pre-rRNA processing protein 0.00552524
BAALC brain and acute leukemia, cytoplasmic 0.00550348
MYBPC2 myosin binding protein C, fast type 0.00549606
SLC22A18 solute carrier family 22, member 18 0.00549597
CAPNS1 calpain, small subunit 1 0.0054871
PLAUR plasminogen activator, urokinase receptor 0.00548311
HSPE1 heat shock 10kDa protein 1 0.00547124
CCN2 cellular communication network factor 2 0.00547053
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.00546796
ABHD11 abhydrolase domain containing 11 0.00546394
ISG20 interferon stimulated exonuclease gene 20kDa 0.00546385
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00545624
DEFB1 defensin, beta 1 0.00545315
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00545191
IQCG IQ motif containing G 0.0054468
MYO1C myosin IC 0.00543604
PSCA prostate stem cell antigen 0.0054169
CXCL13 chemokine (C-X-C motif) ligand 13 0.00540899
ACSF2 acyl-CoA synthetase family member 2 0.00539142
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00538557
HSPB8 heat shock 22kDa protein 8 0.00537852
TNIP1 TNFAIP3 interacting protein 1 0.00537846
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.00536431
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.00535634
MYH7 myosin, heavy chain 7, cardiac muscle, beta 0.00535567
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00534357
FPGS folylpolyglutamate synthase 0.00534245
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00533051
GFPT2 glutamine-fructose-6-phosphate transaminase 2 0.00532959
CHMP7 charged multivesicular body protein 7 0.00532853
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.00532127
ODAM odontogenic, ameloblast asssociated 0.00532119
FOXG1 forkhead box G1 0.00531883
ADGRE5 adhesion G protein-coupled receptor E5 0.00531881
SHCBP1 SHC SH2-domain binding protein 1 0.00531821
ANAPC13 anaphase promoting complex subunit 13 0.00531409
IRF7 interferon regulatory factor 7 0.00530483
SYNGR3 synaptogyrin 3 0.00530301
IGBP1 immunoglobulin (CD79A) binding protein 1 0.00530013
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.00529896
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00529767
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.00529468
CALB1 calbindin 1, 28kDa 0.00528699
PRMT1 protein arginine methyltransferase 1 0.00527887
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00527677
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 0.00527272
OPHN1 oligophrenin 1 0.00526373
ZDHHC7 zinc finger, DHHC-type containing 7 0.00526322
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.00525935
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.00525518
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.0052531
TBX2 T-box 2 0.0052517
C19ORF54 chromosome 19 open reading frame 54 0.00524308

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -0.0181812
CDC20 cell division cycle 20 -0.0168556
BMP4 bone morphogenetic protein 4 -0.0150148
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.014407
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.014344
RGS5 regulator of G-protein signaling 5 -0.0137217
FRZB frizzled-related protein -0.0135067
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0129066
TPSAB1 tryptase alpha/beta 1 -0.0115083
ASPN asporin -0.0113009
RTN1 reticulon 1 -0.0106756
CLC Charcot-Leyden crystal galectin -0.0105172
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.0104612
NCAM1 neural cell adhesion molecule 1 -0.0103435
GREM1 gremlin 1, DAN family BMP antagonist -0.0102097
RCAN2 regulator of calcineurin 2 -0.0101817
FABP4 fatty acid binding protein 4, adipocyte -0.00988095
A2M alpha-2-macroglobulin -0.00985763
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00972916
GET1 guided entry of tail-anchored proteins factor 1 -0.00972256
MYH11 myosin, heavy chain 11, smooth muscle -0.0097094
FASN fatty acid synthase -0.00969561
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00967375
PLN phospholamban -0.00933346
SNAI2 snail family zinc finger 2 -0.00932901
OLFM4 olfactomedin 4 -0.00930387
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00921661
LPAR1 lysophosphatidic acid receptor 1 -0.0091685
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00910289
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00904546
CLCA1 chloride channel accessory 1 -0.00894893
FGL2 fibrinogen-like 2 -0.00894328
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00889481
CPA3 carboxypeptidase A3 (mast cell) -0.00886643
JCHAIN joining chain of multimeric IgA and IgM -0.0087591
PTGIS prostaglandin I2 (prostacyclin) synthase -0.0086843
ADIRF adipogenesis regulatory factor -0.00864919
ACAT2 acetyl-CoA acetyltransferase 2 -0.00856711
CCND2 cyclin D2 -0.00854317
H1-2 H1.2 linker histone, cluster member -0.00853672
MYO1D myosin ID -0.00851308
TOX3 TOX high mobility group box family member 3 -0.00846575
ZG16 zymogen granule protein 16 -0.00842459
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.0084032
ITGA8 integrin, alpha 8 -0.00832095
TMEM47 transmembrane protein 47 -0.00831111
SDC2 syndecan 2 -0.00828612
NUSAP1 nucleolar and spindle associated protein 1 -0.00827129
GNAS GNAS complex locus -0.00824537
RRAGA Ras-related GTP binding A -0.0081671
ADGRF5 adhesion G protein-coupled receptor F5 -0.00815204
RUFY3 RUN and FYVE domain containing 3 -0.00814062
CPB1 carboxypeptidase B1 (tissue) -0.00812898
GAL galanin/GMAP prepropeptide -0.0080792
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.007954
CD9 CD9 molecule -0.00794375
RAPSN receptor-associated protein of the synapse -0.00789192
HMGB3 high mobility group box 3 -0.00783642
COL4A5 collagen, type IV, alpha 5 -0.00783337
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.00778667
CTSK cathepsin K -0.00777368
TMSB15A thymosin beta 15a -0.00776933
PID1 phosphotyrosine interaction domain containing 1 -0.0076222
JAG1 jagged 1 -0.00759919
ARHGAP29 Rho GTPase activating protein 29 -0.00759024
NMU neuromedin U -0.00755947
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -0.00755609
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00752828
PON3 paraoxonase 3 -0.00752395
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00747414
MAOA monoamine oxidase A -0.00747078
PDGFD platelet derived growth factor D -0.00743808
CPE carboxypeptidase E -0.0073976
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.0073957
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00739171
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.0073776
AQP1 aquaporin 1 (Colton blood group) -0.00736271
ZNF22 zinc finger protein 22 -0.00731848
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -0.00731211
TPRKB TP53RK binding protein -0.00729894
DAAM2 dishevelled associated activator of morphogenesis 2 -0.00729097
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -0.00727415
DCLK1 doublecortin-like kinase 1 -0.00727403
PTGDR prostaglandin D2 receptor (DP) -0.00726346
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00726126
HOXB2 homeobox B2 -0.00720014
PRDX2 peroxiredoxin 2 -0.00716099
NID2 nidogen 2 (osteonidogen) -0.00713263
C6 complement component 6 -0.00712211
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -0.00705154
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00702996
DEFA4 defensin, alpha 4, corticostatin -0.00697169
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00696791
H2AX H2A.X variant histone -0.0069663
PTPRD protein tyrosine phosphatase, receptor type, D -0.00692692
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00691973
FOXM1 forkhead box M1 -0.00689487
PEA15 phosphoprotein enriched in astrocytes 15 -0.00689352
SPON1 spondin 1, extracellular matrix protein -0.00688416
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00685349
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00685057
ETNK1 ethanolamine kinase 1 -0.00681769
NEK2 NIMA-related kinase 2 -0.00678966
FAM3C family with sequence similarity 3, member C -0.0067414
CA2 carbonic anhydrase II -0.00673051
HOPX HOP homeobox -0.00672563
C4BPA complement component 4 binding protein, alpha -0.00671399
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00668716
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00663534
ADAMDEC1 ADAM-like, decysin 1 -0.00663457
ZBTB20 zinc finger and BTB domain containing 20 -0.00663254
APOD apolipoprotein D -0.00662941
DYNLL1 dynein, light chain, LC8-type 1 -0.00661382
JAM3 junctional adhesion molecule 3 -0.00660064
CLDND1 claudin domain containing 1 -0.00659453
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00657402
MPC2 mitochondrial pyruvate carrier 2 -0.00655869
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00653729
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00652828
FAM46C family with sequence similarity 46, member C -0.00649846
HMGB2 high mobility group box 2 -0.00648408
ST18 suppression of tumorigenicity 18, zinc finger -0.00648085
SFRP4 secreted frizzled-related protein 4 -0.00647556
ELOVL5 ELOVL fatty acid elongase 5 -0.00644725
CALD1 caldesmon 1 -0.00643185
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00642332
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00642092
CLEC2B C-type lectin domain family 2, member B -0.00641723
SHB Src homology 2 domain containing adaptor protein B -0.0064042
TSPAN5 tetraspanin 5 -0.00639861
NID1 nidogen 1 -0.00639711
FN1 fibronectin 1 -0.00636377
OIP5 Opa interacting protein 5 -0.00635783
PCP4 Purkinje cell protein 4 -0.00634298
CAV1 caveolin 1, caveolae protein, 22kDa -0.00632948
MCM7 minichromosome maintenance complex component 7 -0.0063151
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00631452
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00627084
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00625652
DMTF1 cyclin D binding myb-like transcription factor 1 -0.00620904
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.00620722
ISYNA1 inositol-3-phosphate synthase 1 -0.00617144
GEM GTP binding protein overexpressed in skeletal muscle -0.006165
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.00614927
HYOU1 hypoxia up-regulated 1 -0.00614175
CENPU centromere protein U -0.0061415
NDC80 NDC80 kinetochore complex component -0.00613458
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 -0.00610851
PDGFRL platelet-derived growth factor receptor-like -0.00610076
CARTPT CART prepropeptide -0.00609501
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00607042
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -0.00606127
RFC5 replication factor C (activator 1) 5, 36.5kDa -0.00605926
LEFTY1 left-right determination factor 1 -0.00604973
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00604084
COL4A6 collagen, type IV, alpha 6 -0.00603693
SORBS2 sorbin and SH3 domain containing 2 -0.00603691
CFH complement factor H -0.00600454
DPYSL3 dihydropyrimidinase-like 3 -0.00600345
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00600071
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -0.0059759
CDO1 cysteine dioxygenase type 1 -0.00595578
PPAP2A phosphatidic acid phosphatase type 2A -0.00595525
FABP1 fatty acid binding protein 1, liver -0.0059435
KLF13 Kruppel-like factor 13 -0.00593061
AEBP1 AE binding protein 1 -0.0059237
NOTCH2 notch 2 -0.00590807
CAMP cathelicidin antimicrobial peptide -0.00590438
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00589834
GCG glucagon -0.00588971
METRN meteorin, glial cell differentiation regulator -0.00588309
CKS1B CDC28 protein kinase regulatory subunit 1B -0.00588119
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00584011
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00583496
HAUS3 HAUS augmin-like complex, subunit 3 -0.00580061
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0057937
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00577298
GUCA2A guanylate cyclase activator 2A (guanylin) -0.00574055
WDR7 WD repeat domain 7 -0.00572952
HOXD1 homeobox D1 -0.00572891
HMGB1 high mobility group box 1 -0.005714
ACAT1 acetyl-CoA acetyltransferase 1 -0.00571356
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.0056983
CD36 CD36 molecule (thrombospondin receptor) -0.00568315
LEF1 lymphoid enhancer-binding factor 1 -0.00567204
GINS1 GINS complex subunit 1 (Psf1 homolog) -0.0056652
SCGN secretagogin, EF-hand calcium binding protein -0.00565427
AXL AXL receptor tyrosine kinase -0.0056326
CISH cytokine inducible SH2-containing protein -0.00562867
PHACTR2 phosphatase and actin regulator 2 -0.00562349
SC5D sterol-C5-desaturase -0.00560598
BEX1 brain expressed, X-linked 1 -0.00560407
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.0055909
AQP8 aquaporin 8 -0.00556568
RASL12 RAS-like, family 12 -0.00554627
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0055452
ZNF395 zinc finger protein 395 -0.00554211
CLEC3B C-type lectin domain family 3, member B -0.00553954
CCR2 chemokine (C-C motif) receptor 2 -0.00552619
CNTNAP2 contactin associated protein-like 2 -0.00551633
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.00550297
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -0.00549983
APMAP adipocyte plasma membrane associated protein -0.00549683
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00549443
IFT74 intraflagellar transport 74 -0.00548756
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -0.00548429
TBC1D12 TBC1 domain family, member 12 -0.00547949
ST14 suppression of tumorigenicity 14 (colon carcinoma) -0.0054768
PNN pinin, desmosome associated protein -0.00547417
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -0.00547145
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00546353
EI24 etoposide induced 2.4 -0.00545538
PPA2 pyrophosphatase (inorganic) 2 -0.00544788
CD302 CD302 molecule -0.00542941
CHN2 chimerin 2 -0.00542929
CD200 CD200 molecule -0.00542737
COL8A2 collagen, type VIII, alpha 2 -0.00541885
CCL8 chemokine (C-C motif) ligand 8 -0.00541868
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -0.00541064
MGP matrix Gla protein -0.0054092
TTLL7 tubulin tyrosine ligase-like family member 7 -0.00540763
LPPR1 lipid phosphate phosphatase-related protein type 1 -0.0053802
MPZL2 myelin protein zero-like 2 -0.00536846
CD48 CD48 molecule -0.00536603
RNF130 ring finger protein 130 -0.00535906
TSPAN7 tetraspanin 7 -0.00532432
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -0.00531813
IDO1 indoleamine 2,3-dioxygenase 1 -0.00530909
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00530452
KIAA0930 KIAA0930 -0.0052938
PLIN1 perilipin 1 -0.00529355
SCG5 secretogranin V -0.00529113
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00529109
PLAAT3 phospholipase A and acyltransferase 3 -0.00528636
THBS2 thrombospondin 2 -0.00528131
NT5E 5'-nucleotidase, ecto (CD73) -0.00527761
LRRC49 leucine rich repeat containing 49 -0.00526726
ADCY1 adenylate cyclase 1 (brain) -0.0052517
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00525041
THBS1 thrombospondin 1 -0.00524258
CTBP2 C-terminal binding protein 2 -0.00523599
TEX30 testis expressed 30 -0.00522897
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00522791
RAD23B RAD23 homolog B (S. cerevisiae) -0.00521538
ANKRD10 ankyrin repeat domain 10 -0.00521072
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00520945
CP ceruloplasmin (ferroxidase) -0.00519798
ILF2 interleukin enhancer binding factor 2 -0.0051975