CCR4 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description chemokine (C-C motif) receptor 4|The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1233)
External Link https://ncbi.nlm.nih.gov/gene/1233
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Genes

497 genes differentially expressed following the CCR4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I 0.0133415
SIRT3 sirtuin 3 0.0123786
AMDHD2 amidohydrolase domain containing 2 0.0118463
PDZK1 PDZ domain containing 1 0.0113605
NNMT nicotinamide N-methyltransferase 0.011147
BGN biglycan 0.0110118
C9 complement component 9 0.010704
CRP C-reactive protein, pentraxin-related 0.0102915
NPEPL1 aminopeptidase-like 1 0.0102215
KRT17 keratin 17, type I 0.0100321
KLK5 kallikrein-related peptidase 5 0.00962183
GSTA1 glutathione S-transferase alpha 1 0.00957953
E2F2 E2F transcription factor 2 0.00939104
APOC3 apolipoprotein C-III 0.00930171
STAB1 stabilin 1 0.00918103
VNN1 vanin 1 0.00914273
PCNA proliferating cell nuclear antigen 0.00913324
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.00883688
TACSTD2 tumor-associated calcium signal transducer 2 0.0087915
CCN2 cellular communication network factor 2 0.00873201
LYPD1 LY6/PLAUR domain containing 1 0.00855887
MSLN mesothelin 0.00851606
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00849752
COLEC11 collectin sub-family member 11 0.00842962
F9 coagulation factor IX 0.00839403
TAGLN transgelin 0.0083665
MEF2C myocyte enhancer factor 2C 0.00824309
OXTR oxytocin receptor 0.00821223
SMCO4 single-pass membrane protein with coiled-coil domains 4 0.00811022
APOA1 apolipoprotein A-I 0.00810594
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.00807889
IGFBP4 insulin-like growth factor binding protein 4 0.00800224
SOX9 SRY (sex determining region Y)-box 9 0.00798263
PLK1 polo-like kinase 1 0.00784666
COL2A1 collagen, type II, alpha 1 0.00776135
TM4SF1 transmembrane 4 L six family member 1 0.00769759
ELN elastin 0.00765017
ARG1 arginase 1 0.00763111
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00761049
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.00761018
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.0075861
ALB albumin 0.00757653
ALDOB aldolase B, fructose-bisphosphate 0.00756628
MAGEA1 melanoma antigen family A1 0.00751233
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.00746827
HPR haptoglobin-related protein 0.00745073
CPNE1 copine I 0.00744506
SLC38A4 solute carrier family 38, member 4 0.00740696
GBAP1 glucosidase, beta, acid pseudogene 1 0.00740592
VTN vitronectin 0.00736238
CTSA cathepsin A 0.00733574
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0.00729959
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00725038
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.00716621
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.0071563
LAMP1 lysosomal-associated membrane protein 1 0.00714982
SCAND1 SCAN domain containing 1 0.00712544
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.00711213
SDC4 syndecan 4 0.00709414
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.0070938
FXYD2 FXYD domain containing ion transport regulator 2 0.00708042
MARCKSL1 MARCKS-like 1 0.00702085
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00701965
IFI30 interferon, gamma-inducible protein 30 0.00700191
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.00694492
INHBA inhibin, beta A 0.00693969
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.00693423
HAL histidine ammonia-lyase 0.00689668
KAZN kazrin, periplakin interacting protein 0.00688729
TTR transthyretin 0.00683763
SLPI secretory leukocyte peptidase inhibitor 0.00683578
LUM lumican 0.00682859
APCS amyloid P component, serum 0.00682539
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 0.00679361
SLC16A6 solute carrier family 16, member 6 0.00678297
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00677918
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 0.00677886
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00675691
SRGN serglycin 0.00674707
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 0.00673923
HMOX1 heme oxygenase 1 0.00672103
BST2 bone marrow stromal cell antigen 2 0.00671332
C4BPB complement component 4 binding protein, beta 0.00668163
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.00665513
IGFBP1 insulin-like growth factor binding protein 1 0.00660792
CCNA2 cyclin A2 0.00659606
LY6E lymphocyte antigen 6 complex, locus E 0.00658051
MRPS31 mitochondrial ribosomal protein S31 0.00657624
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.00656715
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.00653352
PLG plasminogen 0.00652984
FST follistatin 0.0065067
FRS2 fibroblast growth factor receptor substrate 2 0.00650548
TNNT1 troponin T type 1 (skeletal, slow) 0.00649812
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.00647451
PEG10 paternally expressed 10 0.00647412
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00642597
C7 complement component 7 0.00642559
DSP desmoplakin 0.00642308
TCTA T-cell leukemia translocation altered 0.00642238
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00641473
JCHAIN joining chain of multimeric IgA and IgM 0.00639515
CXCR4 chemokine (C-X-C motif) receptor 4 0.00634382
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 0.006341
EXT1 exostosin glycosyltransferase 1 0.00633943
IGHMBP2 immunoglobulin mu binding protein 2 0.00633522
COL16A1 collagen, type XVI, alpha 1 0.00629739
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.0062972
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.00629542
RB1 retinoblastoma 1 0.00627352
JADE3 jade family PHD finger 3 0.00627154
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.00626205
G6PC glucose-6-phosphatase, catalytic subunit 0.00624656
AFM afamin 0.00624126
SIDT2 SID1 transmembrane family, member 2 0.00623672
EIF4A1 eukaryotic translation initiation factor 4A1 0.00622527
SLC43A3 solute carrier family 43, member 3 0.00621791
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0062104
JPT1 Jupiter microtubule associated homolog 1 0.00618291
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00617206
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.00617183
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 0.00616522
MAGEA12 melanoma antigen family A12 0.00616108
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.00614559
PLAT plasminogen activator, tissue 0.00612969
KRT7 keratin 7, type II 0.00612178
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 0.00609459
TMEM14A transmembrane protein 14A 0.00605988
KLF6 Kruppel-like factor 6 0.00604859
ENG endoglin 0.00604418
COL9A3 collagen, type IX, alpha 3 0.00603464
ENO1 enolase 1, (alpha) 0.00602565
CRIP2 cysteine-rich protein 2 0.0060217
EVA1B eva-1 homolog B (C. elegans) 0.00595587
TMPRSS4 transmembrane protease, serine 4 0.00595455
HAMP hepcidin antimicrobial peptide 0.00592558
MAGEA3 melanoma antigen family A3 0.00589579
FOXC1 forkhead box C1 0.00588446
RNPS1 RNA binding protein S1, serine-rich domain 0.00587506
HPD 4-hydroxyphenylpyruvate dioxygenase 0.00587287
ANGPTL3 angiopoietin-like 3 0.00586842
RRBP1 ribosome binding protein 1 0.00584441
SH3TC1 SH3 domain and tetratricopeptide repeats 1 0.0058385
CRIP1 cysteine-rich protein 1 (intestinal) 0.00583841
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 0.00583745
TMEM176B transmembrane protein 176B 0.00582946
MAGED2 melanoma antigen family D2 0.00582815
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.00582773
FMO3 flavin containing monooxygenase 3 0.00580808
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00580045
ORM1 orosomucoid 1 0.00578683
AADAC arylacetamide deacetylase 0.00576723
MMP2 matrix metallopeptidase 2 0.00575876
ZGPAT zinc finger, CCCH-type with G patch domain 0.00575107
P3H1 prolyl 3-hydroxylase 1 0.00574027
MAT1A methionine adenosyltransferase I, alpha 0.00571308
CPB2 carboxypeptidase B2 (plasma) 0.00566795
GRAMD1C GRAM domain containing 1C 0.00566156
DCPS decapping enzyme, scavenger 0.00564622
CFHR4 complement factor H-related 4 0.00561474
ACOT7 acyl-CoA thioesterase 7 0.00561081
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00560945
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.00560392
C1QA complement component 1, q subcomponent, A chain 0.00557038
IL17B interleukin 17B 0.00555817
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.00555524
PAH phenylalanine hydroxylase 0.00553477
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00553121
DPYS dihydropyrimidinase 0.00549762
TUBA1A tubulin, alpha 1a 0.00549314
NOS3 nitric oxide synthase 3 (endothelial cell) 0.00548272
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00547632
KLK6 kallikrein-related peptidase 6 0.00546579
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00545717
SMAD6 SMAD family member 6 0.00545587
ARMCX6 armadillo repeat containing, X-linked 6 0.00544195
UBE2S ubiquitin-conjugating enzyme E2S 0.00543651
MEF2A myocyte enhancer factor 2A 0.005417
KRT18 keratin 18, type I 0.00538324
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00538018
PHC2 polyhomeotic homolog 2 (Drosophila) 0.00537896
NRG1 neuregulin 1 0.00536808
IFI27 interferon, alpha-inducible protein 27 0.00536378
MPHOSPH6 M-phase phosphoprotein 6 0.0053283
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.00532503
DLK1 delta-like 1 homolog (Drosophila) 0.00532003
MXRA7 matrix-remodelling associated 7 0.00531421
ZW10 zw10 kinetochore protein 0.0052999
FKBP5 FK506 binding protein 5 0.00529589
THBS1 thrombospondin 1 0.00529101
APOA2 apolipoprotein A-II 0.00528842
GATA6 GATA binding protein 6 0.00528458
CDCA3 cell division cycle associated 3 0.00527899
KCTD12 potassium channel tetramerization domain containing 12 0.00527372
S100A2 S100 calcium binding protein A2 0.00526691
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 0.00526436
PPAN peter pan homolog (Drosophila) 0.00526261
KNG1 kininogen 1 0.00525575
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00525477
COMP cartilage oligomeric matrix protein 0.00524415
RFTN1 raftlin, lipid raft linker 1 0.00524286
ZNF711 zinc finger protein 711 0.00523814
SOBP sine oculis binding protein homolog (Drosophila) 0.00523495
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.00522838
ABAT 4-aminobutyrate aminotransferase 0.00521065
ASS1 argininosuccinate synthase 1 0.00520962
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00520744
THBS2 thrombospondin 2 0.00520488
CCDC85B coiled-coil domain containing 85B 0.0051922
FDXR ferredoxin reductase 0.00518976
SPHK1 sphingosine kinase 1 0.00518386
C5ORF28 chromosome 5 open reading frame 28 0.00517716
F13B coagulation factor XIII, B polypeptide 0.0051715
DOCK4 dedicator of cytokinesis 4 0.00515924
AKR1C4 aldo-keto reductase family 1, member C4 0.00515374
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00514966
DHODH dihydroorotate dehydrogenase (quinone) 0.00513801
FOLR1 folate receptor 1 (adult) 0.00512015
ATOX1 antioxidant 1 copper chaperone 0.00511749
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.00511516
UPB1 ureidopropionase, beta 0.00510852
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 0.00509918
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.00509382
LECT2 leukocyte cell-derived chemotaxin 2 0.00509351
FGFR3 fibroblast growth factor receptor 3 0.00509296
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.00508591
HLA-DRA major histocompatibility complex, class II, DR alpha 0.00508217
TYMS thymidylate synthetase 0.00507988
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00507912
NCALD neurocalcin delta 0.00507595
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00507391
MCAM melanoma cell adhesion molecule 0.00506476
IRX5 iroquois homeobox 5 0.00504642
MTTP microsomal triglyceride transfer protein 0.0050426
ASXL2 additional sex combs like transcriptional regulator 2 0.00503919
CFHR2 complement factor H-related 2 0.00503429
MGMT O-6-methylguanine-DNA methyltransferase 0.00502705
RHOBTB3 Rho-related BTB domain containing 3 0.00502423
FUS FUS RNA binding protein 0.00502389
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 0.00501037
IL17RB interleukin 17 receptor B 0.00500993
FABP1 fatty acid binding protein 1, liver 0.00500898
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.00500385
MRPS30 mitochondrial ribosomal protein S30 0.00500306
SORBS3 sorbin and SH3 domain containing 3 0.00499723
CES1P1 carboxylesterase 1 pseudogene 1 0.00498551
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.00497675
ANO1 anoctamin 1, calcium activated chloride channel 0.00497506

decreased expression

Symbol Name Standardized Value
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0151824
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0129252
BASP1 brain abundant, membrane attached signal protein 1 -0.012635
LYN LYN proto-oncogene, Src family tyrosine kinase -0.0125853
PLN phospholamban -0.0123252
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.011764
AKR1C3 aldo-keto reductase family 1, member C3 -0.0115194
MDFIC MyoD family inhibitor domain containing -0.0111566
ABHD4 abhydrolase domain containing 4 -0.0111455
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0107624
CD38 CD38 molecule -0.0107617
NT5E 5'-nucleotidase, ecto (CD73) -0.0107155
FGF13 fibroblast growth factor 13 -0.0106182
DEPTOR DEP domain containing MTOR-interacting protein -0.0105624
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.0104951
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -0.0104784
VSNL1 visinin-like 1 -0.0104003
CAV1 caveolin 1, caveolae protein, 22kDa -0.0103944
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.0103507
ADM adrenomedullin -0.0102025
COL15A1 collagen, type XV, alpha 1 -0.00997625
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00995987
STC1 stanniocalcin 1 -0.0099523
STK26 serine/threonine protein kinase 26 -0.00993447
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00989157
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0098416
CLCA4 chloride channel accessory 4 -0.00978893
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00970962
FHL1 four and a half LIM domains 1 -0.00963805
LEFTY1 left-right determination factor 1 -0.00950095
NRN1 neuritin 1 -0.00937426
SNAP25 synaptosomal-associated protein, 25kDa -0.00936198
OLFM4 olfactomedin 4 -0.00934825
NIBAN1 niban apoptosis regulator 1 -0.00934212
LMO3 LIM domain only 3 (rhombotin-like 2) -0.0092206
BTG2 BTG family, member 2 -0.00910783
SFRP1 secreted frizzled-related protein 1 -0.00908894
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.0089877
MFAP5 microfibrillar associated protein 5 -0.00895952
FXYD3 FXYD domain containing ion transport regulator 3 -0.00895696
PARM1 prostate androgen-regulated mucin-like protein 1 -0.00893394
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.0088973
VLDLR very low density lipoprotein receptor -0.00878179
MAOA monoamine oxidase A -0.00873638
STOM stomatin -0.00863821
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -0.00862192
HPGDS hematopoietic prostaglandin D synthase -0.00853515
BMP7 bone morphogenetic protein 7 -0.00846234
SYT1 synaptotagmin I -0.00843844
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00837496
PCP4 Purkinje cell protein 4 -0.00824674
YME1L1 YME1-like 1 ATPase -0.00824388
SPART spartin -0.00816749
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -0.00813775
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00813732
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.00812827
LITAF lipopolysaccharide-induced TNF factor -0.00812711
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00809888
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00809369
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00809334
TMPRSS2 transmembrane protease, serine 2 -0.00805225
HLA-DOB major histocompatibility complex, class II, DO beta -0.00804123
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00803905
IGFBP5 insulin-like growth factor binding protein 5 -0.0080363
PPAP2A phosphatidic acid phosphatase type 2A -0.00800472
DES desmin -0.00799412
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00799373
OSR2 odd-skipped related transciption factor 2 -0.00797388
PRKCQ protein kinase C, theta -0.00789429
ESRP1 epithelial splicing regulatory protein 1 -0.00787666
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.00785975
VAV3 vav 3 guanine nucleotide exchange factor -0.00781539
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00777931
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00776047
BCR breakpoint cluster region -0.00772165
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -0.00771832
NEBL nebulette -0.0077145
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00768985
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00768934
GPC4 glypican 4 -0.00761809
CA4 carbonic anhydrase IV -0.00757339
CHRDL1 chordin-like 1 -0.00754193
LTF lactotransferrin -0.0075153
NANOG Nanog homeobox -0.00749235
C3ORF14 chromosome 3 open reading frame 14 -0.00748371
HDAC9 histone deacetylase 9 -0.00745509
SMAGP small cell adhesion glycoprotein -0.0074431
GRB7 growth factor receptor-bound protein 7 -0.00738152
FABP4 fatty acid binding protein 4, adipocyte -0.00734999
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 -0.00733342
TDRD12 tudor domain containing 12 -0.00733279
NELL2 NEL-like 2 (chicken) -0.00727455
GYPC glycophorin C (Gerbich blood group) -0.00725539
CLTB clathrin, light chain B -0.007233
MMP12 matrix metallopeptidase 12 -0.00722085
TGFBR3 transforming growth factor, beta receptor III -0.0071831
SCD5 stearoyl-CoA desaturase 5 -0.00710992
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00708579
MOXD1 monooxygenase, DBH-like 1 -0.00705739
FYB1 FYN binding protein 1 -0.00705126
CD177 CD177 molecule -0.00701194
SERINC5 serine incorporator 5 -0.00699941
DPYD dihydropyrimidine dehydrogenase -0.00698724
VIM vimentin -0.00697662
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00695811
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00695409
POPDC3 popeye domain containing 3 -0.00693921
SORBS1 sorbin and SH3 domain containing 1 -0.00693816
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.0069195
CXADR coxsackie virus and adenovirus receptor -0.00691024
KIAA0226L KIAA0226-like -0.00690661
GPNMB glycoprotein (transmembrane) nmb -0.00689663
MLEC malectin -0.00688478
COL21A1 collagen, type XXI, alpha 1 -0.00685903
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00684749
TGFBI transforming growth factor, beta-induced, 68kDa -0.00684319
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00684292
CA2 carbonic anhydrase II -0.00682953
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00682948
CRISP3 cysteine-rich secretory protein 3 -0.00682057
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00680273
ISG20 interferon stimulated exonuclease gene 20kDa -0.00679426
NAMPT nicotinamide phosphoribosyltransferase -0.00679023
TLCD3A TLC domain containing 3A -0.00678105
AMD1 adenosylmethionine decarboxylase 1 -0.00674305
PYCARD PYD and CARD domain containing -0.00670144
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00664641
ARMCX1 armadillo repeat containing, X-linked 1 -0.00663354
SFRP4 secreted frizzled-related protein 4 -0.00661053
EMX2 empty spiracles homeobox 2 -0.00658513
GPA33 glycoprotein A33 (transmembrane) -0.0065717
NMB neuromedin B -0.00655634
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -0.00655106
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00653671
IFITM1 interferon induced transmembrane protein 1 -0.00653136
MUC4 mucin 4, cell surface associated -0.00651528
ENO2 enolase 2 (gamma, neuronal) -0.00651169
AXL AXL receptor tyrosine kinase -0.00650592
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00645953
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00644704
CLIC2 chloride intracellular channel 2 -0.00644603
MAGEH1 melanoma antigen family H1 -0.00643219
DHDDS dehydrodolichyl diphosphate synthase -0.00640166
GPATCH8 G patch domain containing 8 -0.00640014
RPS17 ribosomal protein S17 -0.0063973
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00639143
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00636346
OPN3 opsin 3 -0.00634794
CYB5R4 cytochrome b5 reductase 4 -0.00633835
PDZD8 PDZ domain containing 8 -0.0063284
CD46 CD46 molecule, complement regulatory protein -0.0063212
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.0062832
PARD3 par-3 family cell polarity regulator -0.0062695
OSBPL10 oxysterol binding protein-like 10 -0.00624917
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00623591
MME membrane metallo-endopeptidase -0.00623206
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00622887
GALC galactosylceramidase -0.00622335
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00620553
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00620056
PTPRO protein tyrosine phosphatase, receptor type, O -0.0061685
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 -0.00615958
PTPRK protein tyrosine phosphatase, receptor type, K -0.00614984
MOCOS molybdenum cofactor sulfurase -0.00613264
KYNU kynureninase -0.00612983
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00612312
CRYM crystallin, mu -0.00612283
NKX3-1 NK3 homeobox 1 -0.00610776
AKAP12 A kinase (PRKA) anchor protein 12 -0.00610578
TGFA transforming growth factor, alpha -0.00608153
FZD5 frizzled class receptor 5 -0.00607419
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00607314
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.0060686
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00606509
ADORA2B adenosine A2b receptor -0.00605743
CLEC2B C-type lectin domain family 2, member B -0.00605038
GSAP gamma-secretase activating protein -0.00602011
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.006004
TMC5 transmembrane channel-like 5 -0.00600389
CADPS2 Ca++-dependent secretion activator 2 -0.00598243
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00595744
CNTNAP2 contactin associated protein-like 2 -0.00595111
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -0.00592991
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.00592551
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00590321
KANK1 KN motif and ankyrin repeat domains 1 -0.00590202
TCEA1 transcription elongation factor A (SII), 1 -0.00589866
TWIST1 twist family bHLH transcription factor 1 -0.00589163
TPD52L1 tumor protein D52-like 1 -0.00588883
SVIL supervillin -0.00588738
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -0.00586788
PADI3 peptidyl arginine deiminase, type III -0.00586501
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -0.0058643
SPRR3 small proline-rich protein 3 -0.00586318
FOXN3 forkhead box N3 -0.00585443
SH3GL3 SH3-domain GRB2-like 3 -0.00581494
GPRASP1 G protein-coupled receptor associated sorting protein 1 -0.00581174
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.00580345
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -0.00580106
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.00579572
DSG3 desmoglein 3 -0.00578557
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00578469
DUOX2 dual oxidase 2 -0.00578158
CTSS cathepsin S -0.00578097
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.00577997
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type -0.00576821
ISCA1 iron-sulfur cluster assembly 1 -0.00576309
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -0.00575917
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -0.00575747
ATP10B ATPase, class V, type 10B -0.00575394
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00574888
HIPK1 homeodomain interacting protein kinase 1 -0.00573147
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -0.00571436
CELF2 CUGBP, Elav-like family member 2 -0.00570752
EGLN1 egl-9 family hypoxia-inducible factor 1 -0.00570445
FBN2 fibrillin 2 -0.00569981
IRF1 interferon regulatory factor 1 -0.0056893
IDO1 indoleamine 2,3-dioxygenase 1 -0.00567748
RSL24D1 ribosomal L24 domain containing 1 -0.00567333
BNC2 basonuclin 2 -0.005672
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00566822
ARHGAP15 Rho GTPase activating protein 15 -0.00564156
NRIP1 nuclear receptor interacting protein 1 -0.0056404
LPAR6 lysophosphatidic acid receptor 6 -0.00563154
INA internexin neuronal intermediate filament protein, alpha -0.00562792
GDE1 glycerophosphodiester phosphodiesterase 1 -0.00562385
NRCAM neuronal cell adhesion molecule -0.00561546
FGFBP1 fibroblast growth factor binding protein 1 -0.0055931
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00557646
SLC25A38 solute carrier family 25, member 38 -0.00556982
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -0.00556862
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -0.005562
PF4 platelet factor 4 -0.00555902
TSPO translocator protein (18kDa) -0.00555784
DOP1B DOP1 leucine zipper like protein B -0.00554966
GDF3 growth differentiation factor 3 -0.00554601
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00554411
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.00554272
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00553773
NDNF neuron-derived neurotrophic factor -0.00552881
AKR1C1 aldo-keto reductase family 1, member C1 -0.00552228
FAM46C family with sequence similarity 46, member C -0.00550931
IFT57 intraflagellar transport 57 -0.00550605
HBD hemoglobin, delta -0.00549593
PYGL phosphorylase, glycogen, liver -0.00548746
SIDT1 SID1 transmembrane family, member 1 -0.00547644
SSPN sarcospan -0.00547496
ZNF423 zinc finger protein 423 -0.00547068
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00546405