CCR5 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description chemokine (C-C motif) receptor 5 (gene/pseudogene)|This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1234)
External Link https://ncbi.nlm.nih.gov/gene/1234
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Genes

499 genes differentially expressed following the CCR5 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CD93 CD93 molecule 0.013584
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0133983
CD36 CD36 molecule (thrombospondin receptor) 0.0133656
IFI27 interferon, alpha-inducible protein 27 0.0118304
TSPAN3 tetraspanin 3 0.0116616
IFI6 interferon, alpha-inducible protein 6 0.0114438
RGS5 regulator of G-protein signaling 5 0.0114068
CXCL14 chemokine (C-X-C motif) ligand 14 0.0112762
COL3A1 collagen, type III, alpha 1 0.0111952
SEPP1 selenoprotein P, plasma, 1 0.011137
MTUS1 microtubule associated tumor suppressor 1 0.0108682
FABP4 fatty acid binding protein 4, adipocyte 0.0106107
VWF von Willebrand factor 0.0105672
LRRC17 leucine rich repeat containing 17 0.0101458
THBS1 thrombospondin 1 0.0101412
ADRA2A adrenoceptor alpha 2A 0.00986929
MX1 MX dynamin-like GTPase 1 0.00965005
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00957083
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00950023
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00925919
ACKR3 atypical chemokine receptor 3 0.0092004
DAXX death-domain associated protein 0.00919579
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00903642
ISG15 ISG15 ubiquitin-like modifier 0.00895648
NID1 nidogen 1 0.00893256
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00884769
LAMP5 lysosomal-associated membrane protein family, member 5 0.00876674
HNMT histamine N-methyltransferase 0.00869653
TGFB3 transforming growth factor, beta 3 0.00868042
PCOLCE procollagen C-endopeptidase enhancer 0.00862128
PLAT plasminogen activator, tissue 0.00857129
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.00851498
COL5A1 collagen, type V, alpha 1 0.00847191
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.0084339
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00842606
GATA6 GATA binding protein 6 0.00830341
BGN biglycan 0.00827823
LGALS13 lectin, galactoside-binding, soluble, 13 0.00825833
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00825314
MX2 MX dynamin-like GTPase 2 0.00820003
PLIN2 perilipin 2 0.00802957
ADGRF5 adhesion G protein-coupled receptor F5 0.00802186
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00801998
ARHGAP29 Rho GTPase activating protein 29 0.00794283
NUTF2 nuclear transport factor 2 0.00786272
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00785524
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00782131
LAMP3 lysosomal-associated membrane protein 3 0.00776226
HLA-DOB major histocompatibility complex, class II, DO beta 0.00772133
CCN2 cellular communication network factor 2 0.00753131
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00752285
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00749657
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00747561
PITX3 paired-like homeodomain 3 0.00745233
MARCKSL1 MARCKS-like 1 0.00742718
PLXDC1 plexin domain containing 1 0.00741971
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00741857
LOX lysyl oxidase 0.00741681
CRELD2 cysteine-rich with EGF-like domains 2 0.00739636
SPARCL1 SPARC-like 1 (hevin) 0.00736319
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00733629
OXA1L oxidase (cytochrome c) assembly 1-like 0.00731099
THBD thrombomodulin 0.0072508
CXCL2 chemokine (C-X-C motif) ligand 2 0.00724436
HLA-DRA major histocompatibility complex, class II, DR alpha 0.00718087
POSTN periostin, osteoblast specific factor 0.00717868
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00711001
AREG amphiregulin 0.00710253
LYZ lysozyme 0.00709731
SRGN serglycin 0.00707042
FZD6 frizzled class receptor 6 0.0070535
XIC X chromosome inactivation center 0.00698709
RGS4 regulator of G-protein signaling 4 0.00697492
CA2 carbonic anhydrase II 0.00694384
ACSL5 acyl-CoA synthetase long-chain family member 5 0.00693701
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.00689589
APOLD1 apolipoprotein L domain containing 1 0.00687434
BST2 bone marrow stromal cell antigen 2 0.0068726
TBX3 T-box 3 0.00685044
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00683003
HSPB1 heat shock 27kDa protein 1 0.00682825
TPBG trophoblast glycoprotein 0.00682595
RTN2 reticulon 2 0.0068047
IFI44 interferon-induced protein 44 0.00680335
MYOF myoferlin 0.00674819
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00672656
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.00672559
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.00669579
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00667718
IFITM1 interferon induced transmembrane protein 1 0.00667148
RCAN1 regulator of calcineurin 1 0.00664425
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00656496
CFDP1 craniofacial development protein 1 0.0065349
FHOD1 formin homology 2 domain containing 1 0.00653385
PALMD palmdelphin 0.00653163
WSB1 WD repeat and SOCS box containing 1 0.00650869
MMP9 matrix metallopeptidase 9 0.00641232
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00636652
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.00636359
TNNT1 troponin T type 1 (skeletal, slow) 0.00635831
MPDZ multiple PDZ domain protein 0.00635543
ACAT1 acetyl-CoA acetyltransferase 1 0.00634588
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.00633893
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.00630743
SLC43A3 solute carrier family 43, member 3 0.00630714
MT1E metallothionein 1E 0.00630094
ANXA3 annexin A3 0.00629806
IL1R1 interleukin 1 receptor, type I 0.00629671
ANPEP alanyl (membrane) aminopeptidase 0.00629428
MT1HL1 metallothionein 1H-like 1 0.00626905
ECM1 extracellular matrix protein 1 0.0062664
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.00621772
WLS wntless Wnt ligand secretion mediator 0.00620408
CFI complement factor I 0.00619354
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00615156
TXNL4A thioredoxin-like 4A 0.00614649
SOX9 SRY (sex determining region Y)-box 9 0.00612792
SAMHD1 SAM domain and HD domain 1 0.00611646
MSL1 male-specific lethal 1 homolog (Drosophila) 0.00611561
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00609256
COL5A2 collagen, type V, alpha 2 0.0060889
GEM GTP binding protein overexpressed in skeletal muscle 0.00607465
KLF4 Kruppel-like factor 4 (gut) 0.00606794
CCNF cyclin F 0.0060534
LGALS4 lectin, galactoside-binding, soluble, 4 0.00604171
CNN3 calponin 3, acidic 0.00603906
ADD3 adducin 3 (gamma) 0.00603706
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00600718
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00600495
PBLD phenazine biosynthesis-like protein domain containing 0.00597695
GIMAP4 GTPase, IMAP family member 4 0.00596484
GAA glucosidase, alpha; acid 0.00596426
KIAA0100 KIAA0100 0.00596189
GBP1 guanylate binding protein 1, interferon-inducible 0.00594862
CRABP2 cellular retinoic acid binding protein 2 0.0059425
PEX2 peroxisomal biogenesis factor 2 0.00593256
TUBA1A tubulin, alpha 1a 0.00593027
TMEM176B transmembrane protein 176B 0.00591131
G0S2 G0/G1 switch 2 0.00591067
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00589555
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00586707
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00585902
SCAND1 SCAN domain containing 1 0.00584732
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.00582206
EFNB2 ephrin-B2 0.00580194
IFITM3 interferon induced transmembrane protein 3 0.00579531
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.00578941
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.0057676
MSX1 msh homeobox 1 0.00573781
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00573318
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00572778
MYH10 myosin, heavy chain 10, non-muscle 0.00570196
WDR7 WD repeat domain 7 0.00568448
EFHD1 EF-hand domain family, member D1 0.00566977
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00566289
CAB39 calcium binding protein 39 0.00566053
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.0056601
RNPS1 RNA binding protein S1, serine-rich domain 0.00564143
ACAA2 acetyl-CoA acyltransferase 2 0.00563362
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00562461
MCAM melanoma cell adhesion molecule 0.00561796
OASL 2'-5'-oligoadenylate synthetase-like 0.00560711
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.00560065
CALML3 calmodulin-like 3 0.00558318
RRAGA Ras-related GTP binding A 0.00557721
IFI44L interferon-induced protein 44-like 0.00555346
HLX H2.0-like homeobox 0.00555255
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00552935
ZCCHC14 zinc finger, CCHC domain containing 14 0.00551774
MT1H metallothionein 1H 0.00550388
GNAS GNAS complex locus 0.0054954
DRAM1 DNA-damage regulated autophagy modulator 1 0.00549047
SIDT2 SID1 transmembrane family, member 2 0.00546899
HOXB2 homeobox B2 0.00546365
CES1 carboxylesterase 1 0.00545866
MT2A metallothionein 2A 0.00545754
ASB13 ankyrin repeat and SOCS box containing 13 0.00545744
KDSR 3-ketodihydrosphingosine reductase 0.00545732
KRT14 keratin 14, type I 0.00545469
GAB2 GRB2-associated binding protein 2 0.0054507
RFTN1 raftlin, lipid raft linker 1 0.00544169
FILIP1L filamin A interacting protein 1-like 0.00543733
CCL2 chemokine (C-C motif) ligand 2 0.00543251
TPD52 tumor protein D52 0.00543235
SELL selectin L 0.00541552
ASPN asporin 0.00540831
CDCA4 cell division cycle associated 4 0.00539413
NAV2 neuron navigator 2 0.00539357
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00538318
PGF placental growth factor 0.00536209
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.0053509
IL1RN interleukin 1 receptor antagonist 0.00534845
TAGLN transgelin 0.00534593
MFAP2 microfibrillar-associated protein 2 0.00533724
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.00533443
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.00532924
PDGFRL platelet-derived growth factor receptor-like 0.00532491
TMEM14A transmembrane protein 14A 0.00532162
CTSG cathepsin G 0.00532157
IL6ST interleukin 6 signal transducer 0.00531869
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.00530884
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.00529508
SP110 SP110 nuclear body protein 0.00528248
MTMR11 myotubularin related protein 11 0.00527386
NPEPL1 aminopeptidase-like 1 0.00526948
TLR4 toll-like receptor 4 0.0052666
FRS2 fibroblast growth factor receptor substrate 2 0.00525247
CAVIN2 caveolae associated protein 2 0.00525213
EDN1 endothelin 1 0.00524668
ZNF160 zinc finger protein 160 0.00524028
MDK midkine (neurite growth-promoting factor 2) 0.00523925
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 0.00523522
DSP desmoplakin 0.00523285
FOXJ3 forkhead box J3 0.00522185
CCNA2 cyclin A2 0.00522099
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 0.00521664
LXN latexin 0.00520863
GRK5 G protein-coupled receptor kinase 5 0.00520538
GOLGA8A golgin A8 family, member A 0.00520396
NEK9 NIMA-related kinase 9 0.00519457
TMEM176A transmembrane protein 176A 0.00517309
PODXL podocalyxin-like 0.00514828
H1-0 H1.0 linker histone 0.00514186
PDGFD platelet derived growth factor D 0.00513436
ADAM19 ADAM metallopeptidase domain 19 0.00511762
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00511216
MBD1 methyl-CpG binding domain protein 1 0.00511009
PCYOX1L prenylcysteine oxidase 1 like 0.00510572
CPNE1 copine I 0.00510093
PTPRK protein tyrosine phosphatase, receptor type, K 0.00509776
FLT1 fms-related tyrosine kinase 1 0.00508823
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00507842
KANK1 KN motif and ankyrin repeat domains 1 0.00506769
MMP11 matrix metallopeptidase 11 0.00506403
CD200 CD200 molecule 0.00505097
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00505024
ICAM2 intercellular adhesion molecule 2 0.00504489
ZCCHC24 zinc finger, CCHC domain containing 24 0.00503403
ETFB electron-transfer-flavoprotein, beta polypeptide 0.0050339
ADM adrenomedullin 0.00501916
GSS glutathione synthetase 0.00501278
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00501209
TPPP3 tubulin polymerization-promoting protein family member 3 0.00499481
CEL carboxyl ester lipase 0.00499217
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.00497085
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.00496969
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 0.00496502
CBFB core-binding factor, beta subunit 0.00494338
CARD8 caspase recruitment domain family, member 8 0.00492559
MVP major vault protein 0.004924

decreased expression

Symbol Name Standardized Value
KRT19 keratin 19, type I -0.0135096
MMP7 matrix metallopeptidase 7 -0.0127797
SSBP2 single-stranded DNA binding protein 2 -0.0126898
TPSAB1 tryptase alpha/beta 1 -0.0124836
KRT7 keratin 7, type II -0.011122
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0108282
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0104341
ASS1 argininosuccinate synthase 1 -0.0101287
S100P S100 calcium binding protein P -0.00964311
PDZK1IP1 PDZK1 interacting protein 1 -0.00945646
SNAP25 synaptosomal-associated protein, 25kDa -0.00938378
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00926621
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00923735
PRUNE2 prune homolog 2 (Drosophila) -0.00892674
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00887193
AKAP8 A kinase (PRKA) anchor protein 8 -0.00867296
FABP6 fatty acid binding protein 6, ileal -0.00822047
FBXO11 F-box protein 11 -0.00809507
PSAT1 phosphoserine aminotransferase 1 -0.00801771
TGM2 transglutaminase 2 -0.00798196
RADX RPA1 related single stranded DNA binding protein, X-linked -0.0079076
STK26 serine/threonine protein kinase 26 -0.00785114
LTF lactotransferrin -0.00777675
IPO13 importin 13 -0.00771813
TPM4 tropomyosin 4 -0.00769734
NELL2 NEL-like 2 (chicken) -0.00763511
SLPI secretory leukocyte peptidase inhibitor -0.00752953
CALB1 calbindin 1, 28kDa -0.0073563
BPGM 2,3-bisphosphoglycerate mutase -0.00732843
P3H2 prolyl 3-hydroxylase 2 -0.00731242
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00729061
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00717827
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00712017
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00693616
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -0.00691927
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00688013
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00677765
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00668617
GAL galanin/GMAP prepropeptide -0.00668211
CTPS1 CTP synthase 1 -0.0066375
NKX3-1 NK3 homeobox 1 -0.00661318
NDP Norrie disease (pseudoglioma) -0.00659293
GPX3 glutathione peroxidase 3 -0.00659037
ITM2A integral membrane protein 2A -0.00656892
INSM1 insulinoma-associated 1 -0.00654677
TXLNA taxilin alpha -0.00649615
GAP43 growth associated protein 43 -0.00646622
MARS1 methionyl-tRNA synthetase 1 -0.00645392
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00643233
DNM1L dynamin 1-like -0.00641182
PON3 paraoxonase 3 -0.00640707
MRPS12 mitochondrial ribosomal protein S12 -0.00634713
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00631605
COCH cochlin -0.00630853
FABP7 fatty acid binding protein 7, brain -0.00628197
QPCT glutaminyl-peptide cyclotransferase -0.00627
CCDC88A coiled-coil domain containing 88A -0.00626637
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00624562
CCND2 cyclin D2 -0.00620994
C5ORF28 chromosome 5 open reading frame 28 -0.00620193
LCK LCK proto-oncogene, Src family tyrosine kinase -0.00619369
TXNIP thioredoxin interacting protein -0.00612241
RBM34 RNA binding motif protein 34 -0.00610859
MAP9 microtubule-associated protein 9 -0.0060781
NLGN1 neuroligin 1 -0.00604916
TGFBI transforming growth factor, beta-induced, 68kDa -0.00603565
HRASLS HRAS-like suppressor -0.0060132
LBH limb bud and heart development -0.00596636
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.0059099
CRYM crystallin, mu -0.00590735
MAOA monoamine oxidase A -0.00589491
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.0058727
GPR87 G protein-coupled receptor 87 -0.00586677
PKM pyruvate kinase, muscle -0.00586486
TWF1 twinfilin actin binding protein 1 -0.00585788
GFAP glial fibrillary acidic protein -0.00585493
ANGPT1 angiopoietin 1 -0.00585168
PCDH9 protocadherin 9 -0.00584773
KYNU kynureninase -0.00583524
S100A11 S100 calcium binding protein A11 -0.0058327
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 -0.00581385
HDAC9 histone deacetylase 9 -0.00578084
CP ceruloplasmin (ferroxidase) -0.00578006
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -0.00576934
SCN3A sodium channel, voltage gated, type III alpha subunit -0.00576129
NDNF neuron-derived neurotrophic factor -0.00575392
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00573077
RBPMS RNA binding protein with multiple splicing -0.00571163
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00570364
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.00567246
GPC4 glypican 4 -0.00565228
RAD23B RAD23 homolog B (S. cerevisiae) -0.00563279
YBX3 Y box binding protein 3 -0.00562848
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00560645
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.00559243
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00558824
CADM1 cell adhesion molecule 1 -0.00556017
TCEAL2 transcription elongation factor A (SII)-like 2 -0.00555016
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00554855
MOXD1 monooxygenase, DBH-like 1 -0.00551481
DBF4 DBF4 zinc finger -0.00550127
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -0.00550012
FAM46C family with sequence similarity 46, member C -0.005497
DSE dermatan sulfate epimerase -0.00547887
SGMS1 sphingomyelin synthase 1 -0.00547224
HBD hemoglobin, delta -0.00546878
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00545184
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00544502
SH3GL2 SH3-domain GRB2-like 2 -0.00544444
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -0.00543758
MAP7 microtubule-associated protein 7 -0.00543526
MSMO1 methylsterol monooxygenase 1 -0.00541977
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00541157
ST18 suppression of tumorigenicity 18, zinc finger -0.00540538
CORO1C coronin, actin binding protein, 1C -0.00540226
TFPI2 tissue factor pathway inhibitor 2 -0.00534126
SYT1 synaptotagmin I -0.005341
CD1E CD1e molecule -0.00532952
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -0.00531891
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -0.00531149
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -0.0053108
TARS1 threonyl-tRNA synthetase 1 -0.0052986
HPGDS hematopoietic prostaglandin D synthase -0.00529738
IRF4 interferon regulatory factor 4 -0.00529241
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -0.00528769
DNASE2 deoxyribonuclease II, lysosomal -0.00525934
TXNDC9 thioredoxin domain containing 9 -0.00523397
FAIM2 Fas apoptotic inhibitory molecule 2 -0.00523122
FHL1 four and a half LIM domains 1 -0.0052297
AP5M1 adaptor-related protein complex 5, mu 1 subunit -0.00522491
CUX1 cut-like homeobox 1 -0.00521952
KLRC3 killer cell lectin-like receptor subfamily C, member 3 -0.00521612
DEPTOR DEP domain containing MTOR-interacting protein -0.00521218
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit -0.00519742
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 -0.00517912
DNM3 dynamin 3 -0.00517583
WASF1 WAS protein family, member 1 -0.00517417
TFB2M transcription factor B2, mitochondrial -0.00517338
GSPT2 G1 to S phase transition 2 -0.00517007
ADGRG2 adhesion G protein-coupled receptor G2 -0.00514763
CD9 CD9 molecule -0.00513823
LITAF lipopolysaccharide-induced TNF factor -0.00512906
TPD52L1 tumor protein D52-like 1 -0.00511859
COL4A6 collagen, type IV, alpha 6 -0.00511709
IL13RA2 interleukin 13 receptor, alpha 2 -0.00511255
PTN pleiotrophin -0.00510852
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00510108
CD46 CD46 molecule, complement regulatory protein -0.00509557
SELENOT selenoprotein T -0.0050931
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -0.00507371
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.00507054
AHSP alpha hemoglobin stabilizing protein -0.00506924
SERINC5 serine incorporator 5 -0.00506904
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -0.00506449
ING3 inhibitor of growth family, member 3 -0.0050559
COL11A1 collagen, type XI, alpha 1 -0.00504371
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00503826
CLDN1 claudin 1 -0.00502556
PCSK2 proprotein convertase subtilisin/kexin type 2 -0.00502541
SLC38A1 solute carrier family 38, member 1 -0.00502308
PSPH phosphoserine phosphatase -0.00498051
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -0.00495298
TLE5 TLE family member 5, transcriptional modulator -0.00493442
RIMS3 regulating synaptic membrane exocytosis 3 -0.00491188
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00490192
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.00489954
BCHE butyrylcholinesterase -0.00488699
IFNG interferon, gamma -0.00488635
CLTC clathrin, heavy chain (Hc) -0.00487921
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.00486921
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A -0.00486806
KIF1A kinesin family member 1A -0.00486588
DENND1B DENN/MADD domain containing 1B -0.00486056
S100A2 S100 calcium binding protein A2 -0.00484582
ATF4 activating transcription factor 4 -0.00484431
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00484115
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00483836
CCL4 chemokine (C-C motif) ligand 4 -0.00483675
LOC283683 uncharacterized LOC283683 -0.00483013
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.00482634
NVL nuclear VCP-like -0.00481328
DUSP2 dual specificity phosphatase 2 -0.00479988
MLXIP MLX interacting protein -0.00479574
PCGF1 polycomb group ring finger 1 -0.00478603
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -0.00477425
VAMP8 vesicle-associated membrane protein 8 -0.00476496
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -0.00476209
GNLY granulysin -0.00475534
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00475386
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) -0.00474624
NR0B1 nuclear receptor subfamily 0, group B, member 1 -0.00473897
PSCA prostate stem cell antigen -0.00472869
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00471843
TESC tescalcin -0.00470414
STAT4 signal transducer and activator of transcription 4 -0.00470276
CDH10 cadherin 10, type 2 (T2-cadherin) -0.00469745
ANO3 anoctamin 3 -0.00469354
PRPS1 phosphoribosyl pyrophosphate synthetase 1 -0.00469097
VLDLR very low density lipoprotein receptor -0.00468018
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00467777
NPTX2 neuronal pentraxin II -0.00467752
ELOVL4 ELOVL fatty acid elongase 4 -0.00466536
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00465441
BCL2L1 BCL2-like 1 -0.00465423
ORC1 origin recognition complex, subunit 1 -0.00464913
FXYD2 FXYD domain containing ion transport regulator 2 -0.00464336
RAB33A RAB33A, member RAS oncogene family -0.00464131
NAP1L2 nucleosome assembly protein 1-like 2 -0.00463575
RPL36AL ribosomal protein L36a-like -0.00461416
XCL1 chemokine (C motif) ligand 1 -0.0046134
ERP29 endoplasmic reticulum protein 29 -0.00461071
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00461061
MXRA7 matrix-remodelling associated 7 -0.00460487
NKX2-2 NK2 homeobox 2 -0.00460447
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00460413
C12ORF29 chromosome 12 open reading frame 29 -0.00458975
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00458073
SSH3 slingshot protein phosphatase 3 -0.00457574
RAB5C RAB5C, member RAS oncogene family -0.00457035
TENM1 teneurin transmembrane protein 1 -0.00456624
PDE4D phosphodiesterase 4D, cAMP-specific -0.00454527
CA8 carbonic anhydrase VIII -0.00454053
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -0.00453104
SDHAF3 succinate dehydrogenase complex assembly factor 3 -0.00451856
PADI3 peptidyl arginine deiminase, type III -0.00451224
CENPU centromere protein U -0.00450126
ADA adenosine deaminase -0.00448702
PRF1 perforin 1 (pore forming protein) -0.00447828
DHDDS dehydrodolichyl diphosphate synthase -0.00447674
KANSL2 KAT8 regulatory NSL complex subunit 2 -0.00447346
ELP5 elongator acetyltransferase complex subunit 5 -0.00447225
RNF41 ring finger protein 41, E3 ubiquitin protein ligase -0.00447169
PROM1 prominin 1 -0.00446486
THAP1 THAP domain containing, apoptosis associated protein 1 -0.00445834
NKX2-1 NK2 homeobox 1 -0.00445249
CCDC86 coiled-coil domain containing 86 -0.00445179
FOXG1 forkhead box G1 -0.00445067
CDK8 cyclin-dependent kinase 8 -0.00444872
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -0.00443776
F3 coagulation factor III (thromboplastin, tissue factor) -0.00443217
VSIG4 V-set and immunoglobulin domain containing 4 -0.00441763
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00441587
MED21 mediator complex subunit 21 -0.00441338
GCLC glutamate-cysteine ligase, catalytic subunit -0.00441025
BCR breakpoint cluster region -0.00440841
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -0.00440772
AGR2 anterior gradient 2 -0.00440268
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -0.00438371
ZNF576 zinc finger protein 576 -0.00437651