| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | chemokine (C-C motif) receptor 6|This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1235) |
| External Link | https://ncbi.nlm.nih.gov/gene/1235 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the CCR6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0192556 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0178635 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0153003 |
| TYRP1 | tyrosinase-related protein 1 | 0.0137681 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0133691 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0119362 |
| PLPBP | pyridoxal phosphate binding protein | 0.0116755 |
| BCHE | butyrylcholinesterase | 0.0114097 |
| DIPK1A | divergent protein kinase domain 1A | 0.0112483 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.0109366 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.0108112 |
| KRT5 | keratin 5, type II | 0.0106342 |
| PLAT | plasminogen activator, tissue | 0.0104226 |
| FABP7 | fatty acid binding protein 7, brain | 0.0103678 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0103321 |
| C7 | complement component 7 | 0.010112 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.0100432 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.00978792 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00966907 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00960654 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.00955057 |
| COPS7A | COP9 signalosome subunit 7A | 0.00952544 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00947043 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00935746 |
| ERLIN2 | ER lipid raft associated 2 | 0.00934233 |
| PRKD3 | protein kinase D3 | 0.00917666 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00917177 |
| AK4 | adenylate kinase 4 | 0.00912727 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00909167 |
| S100A8 | S100 calcium binding protein A8 | 0.00895785 |
| FABP1 | fatty acid binding protein 1, liver | 0.00894596 |
| ATP10B | ATPase, class V, type 10B | 0.0088913 |
| MAGEA3 | melanoma antigen family A3 | 0.00887861 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00882595 |
| PITX3 | paired-like homeodomain 3 | 0.00882439 |
| MT1X | metallothionein 1X | 0.00875801 |
| ANXA6 | annexin A6 | 0.00871844 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00867781 |
| SATB2 | SATB homeobox 2 | 0.00867092 |
| DENND2B | DENN domain containing 2B | 0.00861221 |
| GAS1 | growth arrest-specific 1 | 0.00853266 |
| MT1H | metallothionein 1H | 0.0085188 |
| PCYOX1L | prenylcysteine oxidase 1 like | 0.00847307 |
| HOPX | HOP homeobox | 0.00843904 |
| NEBL | nebulette | 0.00841517 |
| LAGE3 | L antigen family, member 3 | 0.00839865 |
| FAM162A | family with sequence similarity 162, member A | 0.00829655 |
| SFTPA2 | surfactant protein A2 | 0.00828016 |
| FCGBP | Fc fragment of IgG binding protein | 0.00823143 |
| MT1G | metallothionein 1G | 0.00817924 |
| FERMT2 | fermitin family member 2 | 0.00817579 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00800681 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.0080018 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00794103 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.0079177 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00783336 |
| DMBT1 | deleted in malignant brain tumors 1 | 0.00782289 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00781623 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00776923 |
| SDC1 | syndecan 1 | 0.00774821 |
| NSG1 | neuron specific gene family member 1 | 0.00773735 |
| EDN1 | endothelin 1 | 0.00768524 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00767471 |
| BCL2A1 | BCL2-related protein A1 | 0.0076599 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00763414 |
| THY1 | Thy-1 cell surface antigen | 0.00762337 |
| PTPRO | protein tyrosine phosphatase, receptor type, O | 0.00761332 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00760403 |
| RCAN1 | regulator of calcineurin 1 | 0.00759896 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00759779 |
| HTRA1 | HtrA serine peptidase 1 | 0.00745856 |
| DMD | dystrophin | 0.00740995 |
| MMP9 | matrix metallopeptidase 9 | 0.00735096 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.00733815 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00730278 |
| ARG1 | arginase 1 | 0.00729806 |
| LSM1 | LSM1, U6 small nuclear RNA associated | 0.00728045 |
| TNC | tenascin C | 0.00726082 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00724817 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00721409 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00720023 |
| S100A7 | S100 calcium binding protein A7 | 0.00712294 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00710689 |
| LMNB1 | lamin B1 | 0.00707806 |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) | 0.00707489 |
| MARCKSL1 | MARCKS-like 1 | 0.00706053 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00703412 |
| CDC7 | cell division cycle 7 | 0.0070229 |
| KIFAP3 | kinesin-associated protein 3 | 0.00696122 |
| IL2RG | interleukin 2 receptor, gamma | 0.00694439 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00693827 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00693403 |
| EMP2 | epithelial membrane protein 2 | 0.006918 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 0.00691708 |
| DOK5 | docking protein 5 | 0.00689446 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00687983 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00687089 |
| DPEP1 | dipeptidase 1 (renal) | 0.00686162 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00684152 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00679489 |
| TCF21 | transcription factor 21 | 0.00677665 |
| KRT1 | keratin 1, type II | 0.00677219 |
| SFTPC | surfactant protein C | 0.00674045 |
| NRN1 | neuritin 1 | 0.00673909 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00673386 |
| MT1F | metallothionein 1F | 0.00667644 |
| ICAM3 | intercellular adhesion molecule 3 | 0.00663554 |
| MT1M | metallothionein 1M | 0.00661451 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00660691 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00659142 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00657652 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00655725 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00653306 |
| FGFR4 | fibroblast growth factor receptor 4 | 0.00652138 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00651367 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | 0.00645012 |
| BRCA1 | breast cancer 1, early onset | 0.00643766 |
| NREP | neuronal regeneration related protein | 0.00641676 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00639641 |
| DAXX | death-domain associated protein | 0.00639621 |
| LOR | loricrin | 0.00638971 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.00637309 |
| CD200 | CD200 molecule | 0.00636147 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00635528 |
| KIAA0355 | KIAA0355 | 0.00635376 |
| WDR7 | WD repeat domain 7 | 0.00633945 |
| PLS3 | plastin 3 | 0.00632958 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00632554 |
| RPA3 | replication protein A3, 14kDa | 0.0063232 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00631595 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.0062414 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.00623734 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) | 0.00621623 |
| CALML3 | calmodulin-like 3 | 0.00620596 |
| SIRT5 | sirtuin 5 | 0.00620563 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.00619941 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | 0.00618387 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00617036 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | 0.00617015 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.00614714 |
| S100A2 | S100 calcium binding protein A2 | 0.0061358 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00612876 |
| PLN | phospholamban | 0.00612423 |
| SPRR1B | small proline-rich protein 1B | 0.00611567 |
| BGN | biglycan | 0.00609962 |
| LYRM1 | LYR motif containing 1 | 0.00609794 |
| SFTPD | surfactant protein D | 0.0060816 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00607644 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00606748 |
| GLO1 | glyoxalase I | 0.0060539 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.00604348 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00601494 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00601172 |
| PPP1R11 | protein phosphatase 1, regulatory (inhibitor) subunit 11 | 0.0060031 |
| MT1E | metallothionein 1E | 0.00599833 |
| LAPTM5 | lysosomal protein transmembrane 5 | 0.00597707 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00593951 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00593013 |
| MAL | mal, T-cell differentiation protein | 0.00592797 |
| LYRM4 | LYR motif containing 4 | 0.00589248 |
| CERS6 | ceramide synthase 6 | 0.00588317 |
| TRIB2 | tribbles pseudokinase 2 | 0.00587856 |
| SMAGP | small cell adhesion glycoprotein | 0.00586308 |
| NGRN | neugrin, neurite outgrowth associated | 0.00585748 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.00585134 |
| RPA2 | replication protein A2, 32kDa | 0.00582952 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00582651 |
| ADORA2B | adenosine A2b receptor | 0.00582454 |
| COLEC11 | collectin sub-family member 11 | 0.00581901 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00581226 |
| PPT1 | palmitoyl-protein thioesterase 1 | 0.00579627 |
| WT1 | Wilms tumor 1 | 0.00578837 |
| GLUL | glutamate-ammonia ligase | 0.00577697 |
| PNPLA3 | patatin-like phospholipase domain containing 3 | 0.00577616 |
| CCNF | cyclin F | 0.00577341 |
| SF3A3 | splicing factor 3a, subunit 3, 60kDa | 0.0057721 |
| ETV5 | ets variant 5 | 0.00576595 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00575202 |
| MMP12 | matrix metallopeptidase 12 | 0.00573703 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.00572411 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0057226 |
| CFDP1 | craniofacial development protein 1 | 0.00572086 |
| GOLPH3L | golgi phosphoprotein 3-like | 0.00571614 |
| MRPS18B | mitochondrial ribosomal protein S18B | 0.00570374 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | 0.0056966 |
| KRT6A | keratin 6A, type II | 0.00567157 |
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.00566836 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00565842 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00564347 |
| HAS2 | hyaluronan synthase 2 | 0.00563569 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00562722 |
| CCND2 | cyclin D2 | 0.00561124 |
| KRT14 | keratin 14, type I | 0.00559495 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00559125 |
| CCDC47 | coiled-coil domain containing 47 | 0.00558892 |
| GM2A | GM2 ganglioside activator | 0.00557771 |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 | 0.00557451 |
| EDNRB | endothelin receptor type B | 0.00557212 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00557149 |
| ESD | esterase D | 0.00556465 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0055591 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 0.00555898 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.00555814 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00551262 |
| TMEM14A | transmembrane protein 14A | 0.0055086 |
| RGS4 | regulator of G-protein signaling 4 | 0.00549566 |
| RAB15 | RAB15, member RAS oncogene family | 0.00549452 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00549418 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0054874 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00548563 |
| NR1I2 | nuclear receptor subfamily 1, group I, member 2 | 0.00545538 |
| SV2A | synaptic vesicle glycoprotein 2A | 0.00545404 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00545075 |
| FBXO11 | F-box protein 11 | 0.00544631 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00542765 |
| MT2A | metallothionein 2A | 0.00542524 |
| JRKL | JRK-like | 0.00540558 |
| MRPS27 | mitochondrial ribosomal protein S27 | 0.00540218 |
| PLSCR4 | phospholipid scramblase 4 | 0.00539568 |
| XPO7 | exportin 7 | 0.00538491 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00537794 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00537505 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.00536464 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase | 0.0053564 |
| ADD3 | adducin 3 (gamma) | 0.00534583 |
| KIAA0226L | KIAA0226-like | 0.00534356 |
| MX2 | MX dynamin-like GTPase 2 | 0.00534201 |
| PAH | phenylalanine hydroxylase | 0.00531624 |
| KRT2 | keratin 2, type II | 0.00530474 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00529435 |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 0.00528935 |
| GLB1 | galactosidase, beta 1 | 0.00528913 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00528863 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00528379 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00527641 |
| RGS1 | regulator of G-protein signaling 1 | 0.00525572 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00524678 |
| SNU13 | small nuclear ribonucleoprotein 13 | 0.00524474 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | 0.00523055 |
| PLCG1 | phospholipase C, gamma 1 | 0.00522244 |
| TBC1D4 | TBC1 domain family, member 4 | 0.00522149 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00521975 |
| PRSS21 | protease, serine, 21 (testisin) | 0.005219 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.00520343 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.00517733 |
| C12ORF29 | chromosome 12 open reading frame 29 | 0.00516701 |
| DHFR | dihydrofolate reductase | 0.0051564 |
| MRC2 | mannose receptor, C type 2 | 0.00513488 |
| SFTPB | surfactant protein B | 0.00513343 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0250842 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0222682 |
| MAP7 | microtubule-associated protein 7 | -0.0220626 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.0160904 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0159341 |
| STC2 | stanniocalcin 2 | -0.0147816 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0143043 |
| KRT19 | keratin 19, type I | -0.0134031 |
| TPD52L1 | tumor protein D52-like 1 | -0.0131896 |
| VLDLR | very low density lipoprotein receptor | -0.0128735 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.0126557 |
| OSR2 | odd-skipped related transciption factor 2 | -0.0117881 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0112232 |
| PERP | PERP, TP53 apoptosis effector | -0.0111836 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0108146 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0107617 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0105828 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.0105166 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0104721 |
| KRT7 | keratin 7, type II | -0.0104217 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0104082 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0103956 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0103847 |
| G0S2 | G0/G1 switch 2 | -0.0100824 |
| YBX3 | Y box binding protein 3 | -0.0100351 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00984667 |
| DCLK1 | doublecortin-like kinase 1 | -0.0098391 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00983083 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00970291 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00966044 |
| S100A10 | S100 calcium binding protein A10 | -0.00953079 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00939112 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00937384 |
| ADIRF | adipogenesis regulatory factor | -0.0093604 |
| EPCAM | epithelial cell adhesion molecule | -0.0093068 |
| SHTN1 | shootin 1 | -0.0091431 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00912606 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00907484 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00904118 |
| HEBP2 | heme binding protein 2 | -0.00901821 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00891492 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.00889214 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00876353 |
| PLPP2 | phospholipid phosphatase 2 | -0.00872003 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.00850006 |
| S100A11 | S100 calcium binding protein A11 | -0.00847684 |
| CAV2 | caveolin 2 | -0.0083858 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00836817 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00830041 |
| NEFH | neurofilament, heavy polypeptide | -0.00827886 |
| RAB40B | RAB40B, member RAS oncogene family | -0.0081988 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00818359 |
| PLIN1 | perilipin 1 | -0.00816382 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.0081199 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.008091 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00807546 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00801369 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00780452 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00776536 |
| ZFAND5 | zinc finger, AN1-type domain 5 | -0.00775189 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00767518 |
| MYO5C | myosin VC | -0.00760507 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00759192 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00757914 |
| KRT18 | keratin 18, type I | -0.00756397 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -0.00753909 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00750239 |
| OFD1 | oral-facial-digital syndrome 1 | -0.00749799 |
| CTBP2 | C-terminal binding protein 2 | -0.00749355 |
| UGT8 | UDP glycosyltransferase 8 | -0.00746019 |
| MYRF | myelin regulatory factor | -0.00741836 |
| CLU | clusterin | -0.00735857 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.00733313 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00731152 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00730592 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00728438 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00728227 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00727139 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00723498 |
| IRS2 | insulin receptor substrate 2 | -0.00722478 |
| MID1IP1 | MID1 interacting protein 1 | -0.00719109 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00717746 |
| AK1 | adenylate kinase 1 | -0.00717268 |
| APOD | apolipoprotein D | -0.00714953 |
| CPM | carboxypeptidase M | -0.00714921 |
| GSN | gelsolin | -0.00713681 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00712887 |
| PLXND1 | plexin D1 | -0.00708333 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0070652 |
| BAD | BCL2-associated agonist of cell death | -0.00700882 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00696256 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.00688463 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00688373 |
| LARP6 | La ribonucleoprotein domain family, member 6 | -0.00688127 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | -0.00687442 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | -0.00678964 |
| TRIB3 | tribbles pseudokinase 3 | -0.00678816 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00678622 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | -0.00675848 |
| AMOTL2 | angiomotin like 2 | -0.00674918 |
| EREG | epiregulin | -0.00673551 |
| CLDN7 | claudin 7 | -0.00672977 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00672101 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.00671794 |
| RHOD | ras homolog family member D | -0.00671407 |
| HOXC6 | homeobox C6 | -0.00671375 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00669971 |
| CFH | complement factor H | -0.00664948 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00664428 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00660419 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00657626 |
| RTN1 | reticulon 1 | -0.00656738 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00655115 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00655075 |
| CIDEC | cell death-inducing DFFA-like effector c | -0.00652795 |
| PIR | pirin (iron-binding nuclear protein) | -0.00652426 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00651705 |
| MYOF | myoferlin | -0.00651262 |
| TGM2 | transglutaminase 2 | -0.00651154 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00650753 |
| CD14 | CD14 molecule | -0.00650216 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00648624 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00648612 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | -0.00647573 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | -0.00647493 |
| TBC1D12 | TBC1 domain family, member 12 | -0.00644683 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00644401 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00642932 |
| ANXA1 | annexin A1 | -0.00642053 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 | -0.0064184 |
| TRAM1 | translocation associated membrane protein 1 | -0.0063526 |
| DSE | dermatan sulfate epimerase | -0.00634521 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.00634257 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00633527 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00632511 |
| RPL10 | ribosomal protein L10 | -0.00632379 |
| KMT5B | lysine methyltransferase 5B | -0.00630209 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00630127 |
| FA2H | fatty acid 2-hydroxylase | -0.00626892 |
| S100P | S100 calcium binding protein P | -0.00626515 |
| CHGA | chromogranin A | -0.00623569 |
| JMJD1C | jumonji domain containing 1C | -0.00623327 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00623224 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.00622158 |
| ATP9A | ATPase, class II, type 9A | -0.00619238 |
| HHEX | hematopoietically expressed homeobox | -0.00619155 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00616404 |
| NID2 | nidogen 2 (osteonidogen) | -0.00614949 |
| NAV3 | neuron navigator 3 | -0.00614643 |
| SLC38A2 | solute carrier family 38, member 2 | -0.00613339 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00612888 |
| HGD | homogentisate 1,2-dioxygenase | -0.00612835 |
| MIR22HG | MIR22 host gene | -0.00611964 |
| PRNP | prion protein | -0.0061015 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | -0.00608067 |
| RYBP | RING1 and YY1 binding protein | -0.00607622 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00607559 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00606687 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00605697 |
| GOLGA8H | golgin A8 family, member H | -0.00605593 |
| EGR1 | early growth response 1 | -0.00605299 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00604999 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00604585 |
| CD99 | CD99 molecule | -0.00604317 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00604289 |
| FAM117A | family with sequence similarity 117, member A | -0.00602577 |
| ANXA3 | annexin A3 | -0.00601077 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.00598857 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 | -0.00598203 |
| PLCL2 | phospholipase C-like 2 | -0.00596916 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00595803 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0059455 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00594125 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.00593549 |
| FAM189A2 | family with sequence similarity 189, member A2 | -0.00593295 |
| MAG | myelin associated glycoprotein | -0.00592185 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.00592069 |
| NIT1 | nitrilase 1 | -0.0059013 |
| KIF5B | kinesin family member 5B | -0.00587662 |
| FGL2 | fibrinogen-like 2 | -0.00586978 |
| AKAP17A | A kinase (PRKA) anchor protein 17A | -0.00586928 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00585425 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.00585269 |
| CCNG2 | cyclin G2 | -0.00584623 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.00583672 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00582406 |
| GAB2 | GRB2-associated binding protein 2 | -0.00582114 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00578873 |
| TOB1 | transducer of ERBB2, 1 | -0.00578809 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -0.0057789 |
| ABHD4 | abhydrolase domain containing 4 | -0.00576446 |
| PNN | pinin, desmosome associated protein | -0.0057563 |
| ANXA4 | annexin A4 | -0.00574805 |
| MAGEB2 | melanoma antigen family B2 | -0.00574159 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | -0.00572728 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00572494 |
| ANXA5 | annexin A5 | -0.00570877 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00567869 |
| SEPTIN4 | septin 4 | -0.00567726 |
| RCAN2 | regulator of calcineurin 2 | -0.00566781 |
| RRAGA | Ras-related GTP binding A | -0.00565556 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | -0.00565366 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.0056532 |
| PSAP | prosaposin | -0.00565316 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00565086 |
| NCOA3 | nuclear receptor coactivator 3 | -0.00564871 |
| FRMD4B | FERM domain containing 4B | -0.00564761 |
| TPP2 | tripeptidyl peptidase II | -0.00564355 |
| CORO1C | coronin, actin binding protein, 1C | -0.00564344 |
| TBX3 | T-box 3 | -0.00563881 |
| MGLL | monoglyceride lipase | -0.00563699 |
| H1-0 | H1.0 linker histone | -0.00563492 |
| MLXIP | MLX interacting protein | -0.00562513 |
| TLR4 | toll-like receptor 4 | -0.00561858 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.00561686 |
| EIF6 | eukaryotic translation initiation factor 6 | -0.00561167 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.0056043 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00560353 |
| DIXDC1 | DIX domain containing 1 | -0.00560082 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00559148 |
| PDGFD | platelet derived growth factor D | -0.00559103 |
| FNBP1 | formin binding protein 1 | -0.00558832 |
| MOCOS | molybdenum cofactor sulfurase | -0.00558397 |
| HOMER2 | homer scaffolding protein 2 | -0.00557569 |
| EFHD2 | EF-hand domain family, member D2 | -0.00556049 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.00555477 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00553691 |
| RBM47 | RNA binding motif protein 47 | -0.00552772 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00552575 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.00551728 |
| CHGB | chromogranin B | -0.00551658 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00551625 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00551179 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00549221 |
| CPD | carboxypeptidase D | -0.00548708 |
| SCGN | secretagogin, EF-hand calcium binding protein | -0.00548416 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -0.00547469 |
| SOX17 | SRY (sex determining region Y)-box 17 | -0.00546678 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.0054561 |
| TXNRD1 | thioredoxin reductase 1 | -0.00545418 |
| STC1 | stanniocalcin 1 | -0.00545084 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0054501 |
| ZNF22 | zinc finger protein 22 | -0.0054478 |
| ZNF536 | zinc finger protein 536 | -0.00544728 |
| MGST3 | microsomal glutathione S-transferase 3 | -0.00544552 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | -0.00544416 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00543948 |
| KLK6 | kallikrein-related peptidase 6 | -0.00542362 |
| TSPAN15 | tetraspanin 15 | -0.00540987 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00540751 |
