CCR7 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description chemokine (C-C motif) receptor 7|The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 1236)
External Link https://ncbi.nlm.nih.gov/gene/1236
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Genes

500 genes differentially expressed following the CCR7 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.0134862
HSPB1 heat shock 27kDa protein 1 0.0111493
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0109395
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.010784
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.0100973
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.010015
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 0.00953267
ACTB actin, beta 0.00947912
WASHC4 WASH complex subunit 4 0.00942117
A2M alpha-2-macroglobulin 0.0090299
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00887357
MAN2A1 mannosidase, alpha, class 2A, member 1 0.00853081
CXCL9 chemokine (C-X-C motif) ligand 9 0.00851978
PMP22 peripheral myelin protein 22 0.00849968
NAV3 neuron navigator 3 0.00847909
TRIB2 tribbles pseudokinase 2 0.00846322
CXCL13 chemokine (C-X-C motif) ligand 13 0.00830743
ADAMDEC1 ADAM-like, decysin 1 0.00824889
IGFBP5 insulin-like growth factor binding protein 5 0.00824573
CD36 CD36 molecule (thrombospondin receptor) 0.00822513
SPON2 spondin 2, extracellular matrix protein 0.00816154
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00814145
CHI3L2 chitinase 3-like 2 0.00809737
LEF1 lymphoid enhancer-binding factor 1 0.00807377
NPY1R neuropeptide Y receptor Y1 0.00804933
TYRP1 tyrosinase-related protein 1 0.00796721
LUM lumican 0.00788066
SNAP25 synaptosomal-associated protein, 25kDa 0.00787798
XPO7 exportin 7 0.00784261
LXN latexin 0.00778725
VSNL1 visinin-like 1 0.00776754
REG1A regenerating islet-derived 1 alpha 0.00750289
TLR4 toll-like receptor 4 0.00747196
CXCL14 chemokine (C-X-C motif) ligand 14 0.00745449
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00738634
PHACTR2 phosphatase and actin regulator 2 0.00723591
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00719945
RNASE6 ribonuclease, RNase A family, k6 0.00719103
FCMR Fc fragment of IgM receptor 0.00710603
F13A1 coagulation factor XIII, A1 polypeptide 0.00708207
PFDN4 prefoldin subunit 4 0.0070681
PMEL premelanosome protein 0.00706752
SELENOF selenoprotein F 0.00705368
DCT dopachrome tautomerase 0.00704753
LYZ lysozyme 0.00704459
CLCA1 chloride channel accessory 1 0.00702585
SUB1 SUB1 homolog (S. cerevisiae) 0.00699744
CCDC86 coiled-coil domain containing 86 0.00699401
TXLNA taxilin alpha 0.00697471
CD2 CD2 molecule 0.00692873
CNN3 calponin 3, acidic 0.00686834
AIM2 absent in melanoma 2 0.00684483
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0067906
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00674079
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00673441
GREB1 growth regulation by estrogen in breast cancer 1 0.00671233
KRT10 keratin 10, type I 0.00670575
CD84 CD84 molecule 0.00666753
REG3A regenerating islet-derived 3 alpha 0.00666597
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00665428
HSPB8 heat shock 22kDa protein 8 0.00664306
TRA2A transformer 2 alpha homolog (Drosophila) 0.00660993
PLXNC1 plexin C1 0.00660384
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.00659602
GAL galanin/GMAP prepropeptide 0.00657293
ASPN asporin 0.0065084
KRT1 keratin 1, type II 0.00650315
TCTA T-cell leukemia translocation altered 0.00649433
PDLIM1 PDZ and LIM domain 1 0.00647142
C1S complement component 1, s subcomponent 0.00645292
SIAH2 siah E3 ubiquitin protein ligase 2 0.00643635
BEX1 brain expressed, X-linked 1 0.0063595
THOC7 THO complex 7 0.00633238
SLC46A3 solute carrier family 46, member 3 0.00632537
OLFM1 olfactomedin 1 0.00628344
SEPP1 selenoprotein P, plasma, 1 0.00623698
CHGA chromogranin A 0.00620856
DCLK1 doublecortin-like kinase 1 0.00618453
UBB ubiquitin B 0.00618249
CTH cystathionine gamma-lyase 0.00614653
TTC37 tetratricopeptide repeat domain 37 0.00613062
CST3 cystatin C 0.00612563
FCGBP Fc fragment of IgG binding protein 0.0061071
MEN1 multiple endocrine neoplasia I 0.00610003
RGS4 regulator of G-protein signaling 4 0.00609776
COL15A1 collagen, type XV, alpha 1 0.00608965
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00605793
LY96 lymphocyte antigen 96 0.00605467
RRAGA Ras-related GTP binding A 0.00605057
TYR tyrosinase 0.00604741
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00603933
CSTA cystatin A (stefin A) 0.0060052
ADAT1 adenosine deaminase, tRNA-specific 1 0.00599757
SORD sorbitol dehydrogenase 0.0059865
IRF8 interferon regulatory factor 8 0.00598053
HEBP2 heme binding protein 2 0.00597376
C1QB complement component 1, q subcomponent, B chain 0.00594619
STMN2 stathmin 2 0.00591307
NEFM neurofilament, medium polypeptide 0.00588726
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.00586849
LDOC1 leucine zipper, down-regulated in cancer 1 0.00586283
CXCL10 chemokine (C-X-C motif) ligand 10 0.00586119
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00586091
PLTP phospholipid transfer protein 0.00585636
FKBP11 FK506 binding protein 11, 19 kDa 0.00585584
MRPS30 mitochondrial ribosomal protein S30 0.0058096
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.00580626
GZMK granzyme K (granzyme 3; tryptase II) 0.00580422
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.0057978
NES nestin 0.00578382
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.00578364
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00578096
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.0057787
TMEM126B transmembrane protein 126B 0.00576897
RELN reelin 0.00576689
LY86 lymphocyte antigen 86 0.00575696
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.00573313
MGST2 microsomal glutathione S-transferase 2 0.00572621
KRT2 keratin 2, type II 0.00571323
NPY neuropeptide Y 0.00570282
ALG8 ALG8, alpha-1,3-glucosyltransferase 0.00569711
YTHDC2 YTH domain containing 2 0.00569386
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00569122
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 0.00566652
HNMT histamine N-methyltransferase 0.0056322
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.00561987
NUSAP1 nucleolar and spindle associated protein 1 0.00561749
HOPX HOP homeobox 0.00560852
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00560037
TLK2 tousled-like kinase 2 0.0055804
C3ORF14 chromosome 3 open reading frame 14 0.00557873
GET1 guided entry of tail-anchored proteins factor 1 0.00557619
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 0.0055744
ANKRD10 ankyrin repeat domain 10 0.00553741
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00551391
CNTNAP2 contactin associated protein-like 2 0.00550316
NOTCH2NL notch 2 N-terminal like 0.00549943
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 0.00549145
NDUFA4 NDUFA4, mitochondrial complex associated 0.00548799
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.00548437
MMP11 matrix metallopeptidase 11 0.00547245
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.0054559
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00545284
GTF2H5 general transcription factor IIH, polypeptide 5 0.00545185
PANK3 pantothenate kinase 3 0.005443
IDO1 indoleamine 2,3-dioxygenase 1 0.00543805
FASN fatty acid synthase 0.00543216
CAAP1 caspase activity and apoptosis inhibitor 1 0.00542249
SPINK4 serine peptidase inhibitor, Kazal type 4 0.00541974
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.00535986
ALG6 ALG6, alpha-1,3-glucosyltransferase 0.00535549
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.0053425
CHPT1 choline phosphotransferase 1 0.00533669
ITGA7 integrin, alpha 7 0.00533405
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00531412
REG1B regenerating islet-derived 1 beta 0.00530905
CD27 CD27 molecule 0.00529983
LTN1 listerin E3 ubiquitin protein ligase 1 0.00529257
LRRC37A3 leucine rich repeat containing 37, member A3 0.00528762
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.00528098
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.00525456
PLK2 polo-like kinase 2 0.0052432
TNS3 tensin 3 0.00524046
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.00523406
ALDOC aldolase C, fructose-bisphosphate 0.0052041
TOPORS-AS1 TOPORS antisense RNA 1 0.00518243
DMTF1 cyclin D binding myb-like transcription factor 1 0.0051812
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.005176
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase 0.00516967
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) 0.00515889
IGFBP1 insulin-like growth factor binding protein 1 0.00515766
CORO1B coronin, actin binding protein, 1B 0.00515573
RPS17 ribosomal protein S17 0.00515184
CTSH cathepsin H 0.00514089
ENO2 enolase 2 (gamma, neuronal) 0.00513772
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.00513459
SNX10 sorting nexin 10 0.00512566
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.00512088
TSPAN7 tetraspanin 7 0.00512067
THAP12 THAP domain containing 12 0.00510044
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00509948
COL6A2 collagen, type VI, alpha 2 0.00509684
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00509585
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.00508673
SFN stratifin 0.00506783
EFR3A EFR3 homolog A (S. cerevisiae) 0.00506526
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00506342
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.00506102
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00503486
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 0.00503419
CCL19 chemokine (C-C motif) ligand 19 0.00502401
PCP4 Purkinje cell protein 4 0.0050189
ADGRG2 adhesion G protein-coupled receptor G2 0.00500162
FSTL1 follistatin-like 1 0.00499792
DIO2 deiodinase, iodothyronine, type II 0.0049967
PI3 peptidase inhibitor 3, skin-derived 0.00499051
CPQ carboxypeptidase Q 0.00497277
RPL36 ribosomal protein L36 0.00496877
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 0.0049666
CTTN cortactin 0.00496606
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.00495516
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00494989
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.00494533
TMX1 thioredoxin-related transmembrane protein 1 0.00494082
SYNGR2 synaptogyrin 2 0.00492579
MRPS2 mitochondrial ribosomal protein S2 0.00491906
ZNF512B zinc finger protein 512B 0.00491203
DHCR7 7-dehydrocholesterol reductase 0.00489932
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 0.00489527
RNPS1 RNA binding protein S1, serine-rich domain 0.00489335
ANXA2 annexin A2 0.00488089
HSPB6 heat shock protein, alpha-crystallin-related, B6 0.00487957
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00487261
APLP2 amyloid beta (A4) precursor-like protein 2 0.00486629
RBM26 RNA binding motif protein 26 0.00486101
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 0.00485302
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00484733
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.00483779
RAPSN receptor-associated protein of the synapse 0.004831
DPY19L1 dpy-19-like 1 (C. elegans) 0.00482777
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00481255
LARS1 leucyl-tRNA synthetase 1 0.00480367
FGF13 fibroblast growth factor 13 0.00480314
LBH limb bud and heart development 0.00478912
COG5 component of oligomeric golgi complex 5 0.00477583
IL2RB interleukin 2 receptor, beta 0.00476879
EPS8 epidermal growth factor receptor pathway substrate 8 0.00474317
ZNF226 zinc finger protein 226 0.00474131
PRPH peripherin 0.0047412
IGF1 insulin-like growth factor 1 (somatomedin C) 0.0047406
FAM46C family with sequence similarity 46, member C 0.00473626
DEFA6 defensin, alpha 6, Paneth cell-specific 0.00472649
FGL2 fibrinogen-like 2 0.00472615
ATP8B4 ATPase, class I, type 8B, member 4 0.00472092
HSPA13 heat shock protein 70kDa family, member 13 0.00472046
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00471652
RSU1 Ras suppressor protein 1 0.00471604
TIMP1 TIMP metallopeptidase inhibitor 1 0.00471269
TMEM258 transmembrane protein 258 0.00471199
PRDX2 peroxiredoxin 2 0.00470866
TFF1 trefoil factor 1 0.00470173
GATA3 GATA binding protein 3 0.00469094
APOC2 apolipoprotein C-II 0.00468904
CD163 CD163 molecule 0.0046824
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 0.00467397
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.00466575
PLAU plasminogen activator, urokinase 0.004661
WSB2 WD repeat and SOCS box containing 2 0.00465944
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00465819
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.00465604

decreased expression

Symbol Name Standardized Value
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.0138445
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0130689
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0125947
ZNF395 zinc finger protein 395 -0.0125567
SIK1 salt-inducible kinase 1 -0.0116546
RGCC regulator of cell cycle -0.0114081
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.0111938
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0108161
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.0107581
MAT2A methionine adenosyltransferase II, alpha -0.010475
AUTS2 autism susceptibility candidate 2 -0.0103725
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00989255
MSLN mesothelin -0.00984609
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00977227
FAM107A family with sequence similarity 107, member A -0.00970913
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00968494
FOLR1 folate receptor 1 (adult) -0.00958267
BMP2 bone morphogenetic protein 2 -0.00946208
METRN meteorin, glial cell differentiation regulator -0.00940983
SSBP2 single-stranded DNA binding protein 2 -0.00932138
EGR1 early growth response 1 -0.00906752
LAMP3 lysosomal-associated membrane protein 3 -0.0090352
EDN1 endothelin 1 -0.00883534
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00867283
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00862436
NEBL nebulette -0.0086051
MMP10 matrix metallopeptidase 10 -0.00855569
KRT7 keratin 7, type II -0.00854961
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00842744
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.00822303
S100P S100 calcium binding protein P -0.00814985
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00795176
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00784768
LCN2 lipocalin 2 -0.00784078
FOXD1 forkhead box D1 -0.00776055
CLC Charcot-Leyden crystal galectin -0.00773536
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00762455
FAIM Fas apoptotic inhibitory molecule -0.0075517
INHBA inhibin, beta A -0.00751674
ISG15 ISG15 ubiquitin-like modifier -0.00737487
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00735102
EFNA1 ephrin-A1 -0.00728907
HBEGF heparin-binding EGF-like growth factor -0.0072165
TUBA4A tubulin, alpha 4a -0.00721385
RIPK4 receptor-interacting serine-threonine kinase 4 -0.00720583
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00714655
TOR1A torsin family 1, member A (torsin A) -0.00709895
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00705562
AKAP12 A kinase (PRKA) anchor protein 12 -0.00699741
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -0.0069713
ADIRF adipogenesis regulatory factor -0.00694679
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00693694
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00691054
EGR2 early growth response 2 -0.00687958
PLLP plasmolipin -0.00686402
EIF6 eukaryotic translation initiation factor 6 -0.00684165
WWC1 WW and C2 domain containing 1 -0.00680485
ANXA11 annexin A11 -0.00675888
SLPI secretory leukocyte peptidase inhibitor -0.00675104
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.00671078
CLIP2 CAP-GLY domain containing linker protein 2 -0.00665596
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00664064
MYRF myelin regulatory factor -0.00663431
KIAA0040 KIAA0040 -0.00663292
NT5E 5'-nucleotidase, ecto (CD73) -0.00661634
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.00657406
MLF1 myeloid leukemia factor 1 -0.00654899
CRISP3 cysteine-rich secretory protein 3 -0.00653467
TEX10 testis expressed 10 -0.00644602
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00644282
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00643757
MX1 MX dynamin-like GTPase 1 -0.00640837
NPTX2 neuronal pentraxin II -0.00636284
DKK3 dickkopf WNT signaling pathway inhibitor 3 -0.00634451
CAMP cathelicidin antimicrobial peptide -0.00633086
MUC4 mucin 4, cell surface associated -0.00631776
MAL mal, T-cell differentiation protein -0.00631293
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.00631187
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00630444
PENK proenkephalin -0.00628874
PCBP1 poly(rC) binding protein 1 -0.00622604
MUC16 mucin 16, cell surface associated -0.00621982
ITM2C integral membrane protein 2C -0.00621636
MN1 meningioma (disrupted in balanced translocation) 1 -0.0062125
TMPRSS4 transmembrane protease, serine 4 -0.00619755
TP53I3 tumor protein p53 inducible protein 3 -0.00617739
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00617452
IFRD2 interferon-related developmental regulator 2 -0.00615687
RRAD Ras-related associated with diabetes -0.00611815
SFTPA2 surfactant protein A2 -0.00611351
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00608727
INSR insulin receptor -0.00605405
ZBED2 zinc finger, BED-type containing 2 -0.00603729
SOBP sine oculis binding protein homolog (Drosophila) -0.00603556
TM4SF1 transmembrane 4 L six family member 1 -0.00603431
CD9 CD9 molecule -0.00603422
PROM1 prominin 1 -0.00602046
FOXG1 forkhead box G1 -0.00599968
LTBP2 latent transforming growth factor beta binding protein 2 -0.00598626
DOCK9 dedicator of cytokinesis 9 -0.00598435
TGFA transforming growth factor, alpha -0.00597461
JPT2 Jupiter microtubule associated homolog 2 -0.00597183
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.00595015
RFTN1 raftlin, lipid raft linker 1 -0.00594748
CTSV cathepsin V -0.00594166
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00593032
SYBU syntabulin (syntaxin-interacting) -0.00591681
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00589487
CAST calpastatin -0.0058704
HMGA1 high mobility group AT-hook 1 -0.00586075
LAMC2 laminin, gamma 2 -0.00584399
ZNF423 zinc finger protein 423 -0.00583402
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00582053
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 -0.00581291
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.00579866
GPM6A glycoprotein M6A -0.0057973
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -0.00578617
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00577576
PER1 period circadian clock 1 -0.0057696
EIF5 eukaryotic translation initiation factor 5 -0.00575362
TACC2 transforming, acidic coiled-coil containing protein 2 -0.00572494
TFDP1 transcription factor Dp-1 -0.00570899
ACSF2 acyl-CoA synthetase family member 2 -0.00569058
FOLR3 folate receptor 3 (gamma) -0.00568204
CRELD2 cysteine-rich with EGF-like domains 2 -0.00566164
IFIH1 interferon induced with helicase C domain 1 -0.00565923
SCGB2A2 secretoglobin, family 2A, member 2 -0.00564064
TCP1 t-complex 1 -0.00564
RNF167 ring finger protein 167 -0.00563515
TMBIM1 transmembrane BAX inhibitor motif containing 1 -0.00562841
ESRP1 epithelial splicing regulatory protein 1 -0.00559519
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00558757
BHLHE41 basic helix-loop-helix family, member e41 -0.00558388
SGK1 serum/glucocorticoid regulated kinase 1 -0.00557109
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00556575
RABGAP1 RAB GTPase activating protein 1 -0.00554933
ANXA1 annexin A1 -0.00554474
ANXA3 annexin A3 -0.0055245
CDA cytidine deaminase -0.00550072
TMC5 transmembrane channel-like 5 -0.00547952
SFRP1 secreted frizzled-related protein 1 -0.00547341
IVNS1ABP influenza virus NS1A binding protein -0.00546113
DOCK4 dedicator of cytokinesis 4 -0.00543685
CLIC5 chloride intracellular channel 5 -0.00543627
CRYAB crystallin, alpha B -0.00541888
ADD3 adducin 3 (gamma) -0.00541643
PBX3 pre-B-cell leukemia homeobox 3 -0.00540853
AOC1 amine oxidase, copper containing 1 -0.00539092
TPPP3 tubulin polymerization-promoting protein family member 3 -0.00538939
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00538679
APOLD1 apolipoprotein L domain containing 1 -0.00536306
TWIST1 twist family bHLH transcription factor 1 -0.00535991
HTRA1 HtrA serine peptidase 1 -0.00535632
AQP1 aquaporin 1 (Colton blood group) -0.00534425
HSPA1A heat shock 70kDa protein 1A -0.0053393
E2F3 E2F transcription factor 3 -0.00532723
MGLL monoglyceride lipase -0.0053236
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00530289
FOXC1 forkhead box C1 -0.00530066
FCN3 ficolin (collagen/fibrinogen domain containing) 3 -0.00526782
SMAD3 SMAD family member 3 -0.00526018
AREG amphiregulin -0.0052591
KRT13 keratin 13, type I -0.00525095
SGCE sarcoglycan, epsilon -0.00524105
PER2 period circadian clock 2 -0.00523098
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00520345
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00520007
MT1M metallothionein 1M -0.00518735
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.00516993
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00516938
SIRPA signal-regulatory protein alpha -0.00515963
TFPI2 tissue factor pathway inhibitor 2 -0.00515171
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.00513541
DEFB1 defensin, beta 1 -0.00512799
FDX1 ferredoxin 1 -0.00511896
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -0.00509013
CALM3 calmodulin 3 (phosphorylase kinase, delta) -0.00507929
LAMB3 laminin, beta 3 -0.00507749
SYNM synemin, intermediate filament protein -0.00506168
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00504291
SORBS3 sorbin and SH3 domain containing 3 -0.00503696
TJP2 tight junction protein 2 -0.00503105
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00503096
KLF9 Kruppel-like factor 9 -0.00502761
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -0.00502563
PTPRK protein tyrosine phosphatase, receptor type, K -0.00501904
MGMT O-6-methylguanine-DNA methyltransferase -0.00501737
LIMK2 LIM domain kinase 2 -0.00501013
GRAMD1C GRAM domain containing 1C -0.00500996
ACKR3 atypical chemokine receptor 3 -0.00500772
WLS wntless Wnt ligand secretion mediator -0.00500617
HAS1 hyaluronan synthase 1 -0.00499617
SDC4 syndecan 4 -0.00499448
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -0.00498207
HNRNPF heterogeneous nuclear ribonucleoprotein F -0.00497878
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00496083
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00496026
MET MET proto-oncogene, receptor tyrosine kinase -0.00495492
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00495054
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) -0.00493779
MVP major vault protein -0.0049343
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -0.00492912
KLK10 kallikrein-related peptidase 10 -0.00492307
TES testin LIM domain protein -0.00492206
SASH1 SAM and SH3 domain containing 1 -0.00492151
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -0.00490938
DEFA4 defensin, alpha 4, corticostatin -0.00489892
VAMP8 vesicle-associated membrane protein 8 -0.00487084
FZD10 frizzled class receptor 10 -0.00486805
ODC1 ornithine decarboxylase 1 -0.00486181
EML1 echinoderm microtubule associated protein like 1 -0.00484732
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -0.00484674
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00484358
PNMA8A PNMA family member 8A -0.00484199
SPINT1 serine peptidase inhibitor, Kunitz type 1 -0.00484189
BAMBI BMP and activin membrane-bound inhibitor -0.00483398
FST follistatin -0.00482199
CDV3 CDV3 homolog (mouse) -0.004812
CALB1 calbindin 1, 28kDa -0.00481181
VWF von Willebrand factor -0.00481166
IL1R1 interleukin 1 receptor, type I -0.0047917
CCN2 cellular communication network factor 2 -0.0047861
MCM7 minichromosome maintenance complex component 7 -0.0047787
SNX13 sorting nexin 13 -0.00476925
RAB40B RAB40B, member RAS oncogene family -0.00476867
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00476738
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00476583
BTG3 BTG family, member 3 -0.00476166
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00475853
TSPAN1 tetraspanin 1 -0.0047499
WNT5A wingless-type MMTV integration site family, member 5A -0.00474519
ALDOB aldolase B, fructose-bisphosphate -0.0047418
PKP4 plakophilin 4 -0.00473958
OLIG2 oligodendrocyte lineage transcription factor 2 -0.00473875
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00472392
EPAS1 endothelial PAS domain protein 1 -0.004723
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -0.00471963
FBP1 fructose-1,6-bisphosphatase 1 -0.0047185
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -0.00471087
IFI44 interferon-induced protein 44 -0.00470218
SFTPB surfactant protein B -0.00469159
SOWAHC sosondowah ankyrin repeat domain family member C -0.00468737
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.00468713
SCGB2A1 secretoglobin, family 2A, member 1 -0.00468467
SPRR3 small proline-rich protein 3 -0.00468042
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.0046777
TSPAN8 tetraspanin 8 -0.0046719
TRAF4 TNF receptor-associated factor 4 -0.00466407
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -0.00466162
ZNF165 zinc finger protein 165 -0.00466151