| Dataset | Pathway Commons Protein-Protein Interactions |
| Category | physical interactions |
| Type | interacting protein |
| Description | chemokine (C-C motif) receptor 7|The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 1236) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/1236 |
| Similar Terms | |
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7 interacting proteins for CCR7 from the Pathway Commons Protein-Protein Interactions dataset.
