CCT-031374 Gene Set
Genes
13 genes differentially expressed following the CCT-031374 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INSIG1
|
insulin induced gene 1
|
7.59435
|
|
GNPDA1
|
glucosamine-6-phosphate deaminase 1
|
4.36119
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
3.94672
|
|
MSMO1
|
methylsterol monooxygenase 1
|
3.87691
|
|
NPC1
|
Niemann-Pick disease, type C1
|
3.81681
|
|
SQLE
|
squalene epoxidase
|
3.71788
|
|
LSS
|
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
|
3.65077
|
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
3.60123
|
|
FDPS
|
farnesyl diphosphate synthase
|
3.44813
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
3.13873
|
|
DHCR7
|
7-dehydrocholesterol reductase
|
3.12336
|
|
MVD
|
mevalonate (diphospho) decarboxylase
|
3.05562
|
|
ERG28
|
ergosterol biosynthesis 28 homolog
|
3.0185
|
