CCT-251545 Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

44 genes differentially expressed following the CCT-251545 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 5.44614
RPS5 ribosomal protein S5 4.073
EMX2 empty spiracles homeobox 2 3.6738
PRPF4 pre-mRNA processing factor 4 3.54004
SKIL SKI-like proto-oncogene 3.51767
WASHC4 WASH complex subunit 4 3.45597
MBD5 methyl-CpG binding domain protein 5 3.43589
APTX aprataxin 3.24853
XPO4 exportin 4 3.2201
IFRD2 interferon-related developmental regulator 2 3.20059
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 3.20026
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 3.10568
CGREF1 cell growth regulator with EF-hand domain 1 3.09642
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 3.09389
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 3.07816
LRPPRC leucine-rich pentatricopeptide repeat containing 3.07455
NOP10 NOP10 ribonucleoprotein 3.06002
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 3.02894
FZD5 frizzled class receptor 5 3.01621

decreased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 -6.82178
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -5.8952
MAMLD1 mastermind-like domain containing 1 -4.61994
H2BC12 H2B clustered histone 12 -4.50001
GTSE1 G-2 and S-phase expressed 1 -3.81177
SOX10 SRY (sex determining region Y)-box 10 -3.7871
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -3.66021
CD40 CD40 molecule, TNF receptor superfamily member 5 -3.46222
PNMT phenylethanolamine N-methyltransferase -3.38543
SSX3 synovial sarcoma, X breakpoint 3 -3.36409
USP11 ubiquitin specific peptidase 11 -3.34485
TROAP trophinin associated protein -3.32728
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 -3.32303
DSCAM Down syndrome cell adhesion molecule -3.31602
MFGE8 milk fat globule-EGF factor 8 protein -3.30083
ANKRD10 ankyrin repeat domain 10 -3.22088
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 -3.20139
CDCA3 cell division cycle associated 3 -3.18285
CENPF centromere protein F, 350/400kDa -3.13501
REEP2 receptor accessory protein 2 -3.13416
KAT2B K(lysine) acetyltransferase 2B -3.12553
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.1223
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 -3.11989
GVINP1 GTPase, very large interferon inducible pseudogene 1 -3.06603
PLA2G2D phospholipase A2, group IID -3.03337