CCT4 Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description chaperonin containing TCP1, subunit 4 (delta)|The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 10575)
External Link http://www.ncbi.nlm.nih.gov/gene/10575
Similar Terms
Downloads & Tools

Genes

121 interacting proteins for hub protein CCT4 from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTA1 actin, alpha 1, skeletal muscle
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTB actin, beta
ADARB1 adenosine deaminase, RNA-specific, B1
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
ANGPTL6 angiopoietin-like 6
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
ART5 ADP-ribosyltransferase 5
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1
BCAS2 breast carcinoma amplified sequence 2
CA6 carbonic anhydrase VI
CBR1 carbonyl reductase 1
CCL1 chemokine (C-C motif) ligand 1
CCNE1 cyclin E1
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CDC20 cell division cycle 20
CDK9 cyclin-dependent kinase 9
CELA1 chymotrypsin-like elastase family, member 1
CFAP52 cilia and flagella associated protein 52
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNOT1 CCR4-NOT transcription complex, subunit 1
CPA2 carboxypeptidase A2 (pancreatic)
CTR9 CTR9, Paf1/RNA polymerase II complex component
CUL3 cullin 3
CYLD cylindromatosis (turban tumor syndrome)
DEFA1 defensin, alpha 1
DIAPH3 diaphanous-related formin 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DPH2 DPH2 homolog (S. cerevisiae)
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
ENG endoglin
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
GABARAPL1 GABA(A) receptor-associated protein like 1
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GLI2 GLI family zinc finger 2
GNLY granulysin
GPN1 GPN-loop GTPase 1
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
HAP1 huntingtin-associated protein 1
HGH1 HGH1 homolog (S. cerevisiae)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
IGBP1 immunoglobulin (CD79A) binding protein 1
L1RE1 LINE1 retrotransposable element 1
LSP1 lymphocyte-specific protein 1
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAPK13 mitogen-activated protein kinase 13
MBD5 methyl-CpG binding domain protein 5
MCHR1 melanin-concentrating hormone receptor 1
MED9 mediator complex subunit 9
MEPCE methylphosphate capping enzyme
MORF4 mortality factor 4 (pseudogene)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAP1L3 nucleosome assembly protein 1-like 3
NCBP2 nuclear cap binding protein subunit 2, 20kDa
NDNL2 necdin-like 2
NR0B2 nuclear receptor subfamily 0, group B, member 2
PFDN1 prefoldin subunit 1
PGK1 phosphoglycerate kinase 1
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PPP4C protein phosphatase 4, catalytic subunit
PRPF19 pre-mRNA processing factor 19
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PRPF8 pre-mRNA processing factor 8
PTK2B protein tyrosine kinase 2 beta
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAD50 RAD50 homolog (S. cerevisiae)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPN1 ribophorin I
RRP1 ribosomal RNA processing 1
RYBP RING1 and YY1 binding protein
S100A8 S100 calcium binding protein A8
SAI1 suppression of anchorage independence 1
SEH1L SEH1-like (S. cerevisiae)
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIL1 SIL1 nucleotide exchange factor
SIN3A SIN3 transcription regulator family member A
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SMAD1 SMAD family member 1
SMC2 structural maintenance of chromosomes 2
SPP1 secreted phosphoprotein 1
SPPL3 signal peptide peptidase like 3
SPRR3 small proline-rich protein 3
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STK24 serine/threonine kinase 24
STRN striatin, calmodulin binding protein
STRN3 striatin, calmodulin binding protein 3
STRN4 striatin, calmodulin binding protein 4
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
TAZ tafazzin
TBK1 TANK-binding kinase 1
TCP1 t-complex 1
TRAPPC9 trafficking protein particle complex 9
TRIM21 tripartite motif containing 21
TROVE2 TROVE domain family, member 2
USO1 USO1 vesicle transport factor
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDHD1 WD repeat and HMG-box DNA binding protein 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta