CD19 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description CD19 molecule|Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 930)
External Link http://www.ncbi.nlm.nih.gov/gene/930
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131 interacting proteins for CD19 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABI1 abl-interactor 1
ABI2 abl-interactor 2
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADAM10 ADAM metallopeptidase domain 10
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANXA6 annexin A6
ARID3A AT rich interactive domain 3A (BRIGHT-like)
BAIAP2 BAI1-associated protein 2
BCR breakpoint cluster region
BLNK B-cell linker
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
BTK Bruton agammaglobulinemia tyrosine kinase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD22 CD22 molecule
CD247 CD247 molecule
CD28 CD28 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD63 CD63 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CD80 CD80 molecule
CD81 CD81 molecule
CD82 CD82 molecule
CD86 CD86 molecule
CD9 CD9 molecule
CNTRL centriolin
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CR2 complement component (3d/Epstein Barr virus) receptor 2
CUX1 cut-like homeobox 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAAM1 dishevelled associated activator of morphogenesis 1
ECT2 epithelial cell transforming 2
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF16 fibroblast growth factor 16
FGF17 fibroblast growth factor 17
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF20 fibroblast growth factor 20
FGF22 fibroblast growth factor 22
FGF23 fibroblast growth factor 23
FGF3 fibroblast growth factor 3
FGF4 fibroblast growth factor 4
FGF5 fibroblast growth factor 5
FGF6 fibroblast growth factor 6
FGF7 fibroblast growth factor 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR1OP FGFR1 oncogene partner
FGFR1OP2 FGFR1 oncogene partner 2
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GALK1 galactokinase 1
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
GTF2I general transcription factor IIi
HLA-A major histocompatibility complex, class I, A
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFITM1 interferon induced transmembrane protein 1
IGHD immunoglobulin heavy constant delta
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker)
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker)
IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker)
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IGLC2 immunoglobulin lambda constant 2 (Kern-Oz- marker)
IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker)
IGLC6 immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene)
IGLL1 immunoglobulin lambda-like polypeptide 1
IGSF8 immunoglobulin superfamily, member 8
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITK IL2-inducible T-cell kinase
KL klotho
KLB klotho beta
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAPK1 mitogen-activated protein kinase 1
MCAM melanoma cell adhesion molecule
MME membrane metallo-endopeptidase
MYO18A myosin XVIIIA
NCKAP1 NCK-associated protein 1
PDIA6 protein disulfide isomerase family A, member 6
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PTGFRN prostaglandin F2 receptor inhibitor
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RFTN1 raftlin, lipid raft linker 1
RHOA ras homolog family member A
SH3KBP1 SH3-domain kinase binding protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SOS1 son of sevenless homolog 1 (Drosophila)
SYK spleen tyrosine kinase
TEC tec protein tyrosine kinase
TFRC transferrin receptor
TRIM24 tripartite motif containing 24
TSPAN14 tetraspanin 14
TSPAN9 tetraspanin 9
TXK TXK tyrosine kinase
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
WASF1 WAS protein family, member 1
WASF2 WAS protein family, member 2
WASF3 WAS protein family, member 3
ZMYM2 zinc finger, MYM-type 2