CD1A Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description CD1a molecule|This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 909)
External Link http://www.ncbi.nlm.nih.gov/gene/909
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8 interacting proteins for CD1A from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
B2M beta-2-microglobulin
CD1B CD1b molecule
CD1C CD1c molecule
CD8A CD8a molecule
DGAT1 diacylglycerol O-acyltransferase 1
KCTD5 potassium channel tetramerization domain containing 5
UBTD1 ubiquitin domain containing 1
VWA5A von Willebrand factor A domain containing 5A