CD2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description CD2 molecule|CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010] (NCBI Entrez Gene Database, 914)
External Link http://www.ncbi.nlm.nih.gov/gene/914
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Genes

21 interacting proteins for CD2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CD247 CD247 molecule
CD2AP CD2-associated protein
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CD4 CD4 molecule
CD48 CD48 molecule
CD5 CD5 molecule
CD53 CD53 molecule
CD58 CD58 molecule
CD59 CD59 molecule, complement regulatory protein
EP300 E1A binding protein p300
FYN FYN proto-oncogene, Src family tyrosine kinase
ITK IL2-inducible T-cell kinase
LCK LCK proto-oncogene, Src family tyrosine kinase
LGALS1 lectin, galactoside-binding, soluble, 1
LYAR Ly1 antibody reactive
MXD1 MAX dimerization protein 1
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTPRC protein tyrosine phosphatase, receptor type, C
SH3KBP1 SH3-domain kinase binding protein 1
SP1 Sp1 transcription factor
UBC ubiquitin C