| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | CD209 molecule|This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 10332; often referred to as L-SIGN). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.[provided by RefSeq, Feb 2009] (NCBI Entrez Gene Database, 30835) |
| External Link | https://ncbi.nlm.nih.gov/gene/30835 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the CD209 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAGEA3 | melanoma antigen family A3 | 0.0153161 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0120128 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.0108477 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0107711 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0105455 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0105049 |
| KRT7 | keratin 7, type II | 0.00999864 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00984161 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00955477 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00910323 |
| PROM1 | prominin 1 | 0.00889906 |
| MAGEA12 | melanoma antigen family A12 | 0.00872603 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00838594 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | 0.00824132 |
| FASN | fatty acid synthase | 0.00806545 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00805953 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00805618 |
| TGM2 | transglutaminase 2 | 0.00805498 |
| CHN1 | chimerin 1 | 0.00804615 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00800524 |
| TNS1 | tensin 1 | 0.00788366 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.0077874 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00769964 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00769781 |
| SQLE | squalene epoxidase | 0.00766122 |
| PPL | periplakin | 0.0076166 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.00758851 |
| COPS7A | COP9 signalosome subunit 7A | 0.00757191 |
| CHKB | choline kinase beta | 0.00756365 |
| OBSL1 | obscurin-like 1 | 0.00748702 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0074056 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00740431 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00737862 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00732957 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00727523 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00717942 |
| PLXNB2 | plexin B2 | 0.00715466 |
| SYNM | synemin, intermediate filament protein | 0.00714902 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00709394 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.00708914 |
| FADS1 | fatty acid desaturase 1 | 0.00703027 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.00702547 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00700662 |
| H1-0 | H1.0 linker histone | 0.00691718 |
| NMU | neuromedin U | 0.00690181 |
| CFB | complement factor B | 0.00686496 |
| ZNF395 | zinc finger protein 395 | 0.00685105 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00679039 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00676718 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.00675147 |
| SNX13 | sorting nexin 13 | 0.00671485 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00668899 |
| PRAME | preferentially expressed antigen in melanoma | 0.00665 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00663126 |
| KRT18 | keratin 18, type I | 0.00659666 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00658528 |
| SVIL | supervillin | 0.00652496 |
| TSPYL5 | TSPY-like 5 | 0.00649119 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.00644991 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00642932 |
| TBC1D16 | TBC1 domain family, member 16 | 0.00638845 |
| AGRN | agrin | 0.00638231 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00635003 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.00633818 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00631129 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 0.00625472 |
| GANAB | glucosidase, alpha; neutral AB | 0.00619098 |
| PRKD3 | protein kinase D3 | 0.00618582 |
| PMP22 | peripheral myelin protein 22 | 0.00618108 |
| KIF18B | kinesin family member 18B | 0.00611473 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00610614 |
| RAPSN | receptor-associated protein of the synapse | 0.00609977 |
| ODC1 | ornithine decarboxylase 1 | 0.0060796 |
| NXN | nucleoredoxin | 0.00602779 |
| PCGF2 | polycomb group ring finger 2 | 0.00599054 |
| CRTC3 | CREB regulated transcription coactivator 3 | 0.00596073 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.00590376 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.00588912 |
| NKX3-1 | NK3 homeobox 1 | 0.00585667 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00584814 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.00584628 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00584241 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00581032 |
| HBB | hemoglobin, beta | 0.00581001 |
| CBS | cystathionine-beta-synthase | 0.00576029 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.00575742 |
| MMP7 | matrix metallopeptidase 7 | 0.00573721 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | 0.00573683 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00569036 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00568638 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.00568103 |
| RAB13 | RAB13, member RAS oncogene family | 0.00567925 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00567915 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 0.00567646 |
| GATA2 | GATA binding protein 2 | 0.00566733 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00564837 |
| SPPL2B | signal peptide peptidase like 2B | 0.0056475 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00563046 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00561837 |
| GNAS | GNAS complex locus | 0.0056113 |
| MEIS2 | Meis homeobox 2 | 0.00559847 |
| RAB21 | RAB21, member RAS oncogene family | 0.00559729 |
| STXBP2 | syntaxin binding protein 2 | 0.00558695 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00556047 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00555898 |
| FDPS | farnesyl diphosphate synthase | 0.00555335 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00554351 |
| MLF2 | myeloid leukemia factor 2 | 0.00548018 |
| ARG2 | arginase 2 | 0.00544785 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00543847 |
| PHF20 | PHD finger protein 20 | 0.00543365 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00541678 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00538714 |
| EMILIN1 | elastin microfibril interfacer 1 | 0.00538517 |
| NFIB | nuclear factor I/B | 0.00538371 |
| PRKCA | protein kinase C, alpha | 0.00535178 |
| LAMA5 | laminin, alpha 5 | 0.00533449 |
| S100A8 | S100 calcium binding protein A8 | 0.00532831 |
| PDLIM4 | PDZ and LIM domain 4 | 0.0053139 |
| CDC7 | cell division cycle 7 | 0.00530824 |
| PHF10 | PHD finger protein 10 | 0.00528062 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.00526967 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 0.00526526 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 | 0.00526004 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.00524984 |
| CRIP2 | cysteine-rich protein 2 | 0.00524916 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00524827 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00524384 |
| CCDC47 | coiled-coil domain containing 47 | 0.00522098 |
| SFTPB | surfactant protein B | 0.00522043 |
| IGSF3 | immunoglobulin superfamily, member 3 | 0.00520736 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00519994 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.00519345 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | 0.00518735 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | 0.00518674 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.00516211 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00515277 |
| CHRDL1 | chordin-like 1 | 0.00514991 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 0.00514612 |
| PKP4 | plakophilin 4 | 0.0051395 |
| KIF20A | kinesin family member 20A | 0.00513676 |
| NPHP4 | nephronophthisis 4 | 0.00509869 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00508482 |
| NF2 | neurofibromin 2 (merlin) | 0.00508368 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.00505893 |
| GLB1 | galactosidase, beta 1 | 0.00505163 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.00504568 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 0.00503713 |
| GTPBP1 | GTP binding protein 1 | 0.0050361 |
| INTS1 | integrator complex subunit 1 | 0.00503032 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00502581 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0050161 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00501259 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.00501195 |
| IQCE | IQ motif containing E | 0.00500097 |
| SPHK1 | sphingosine kinase 1 | 0.00498446 |
| KAZN | kazrin, periplakin interacting protein | 0.00498185 |
| ELN | elastin | 0.00493145 |
| DCP2 | decapping mRNA 2 | 0.00491909 |
| LOXL1 | lysyl oxidase-like 1 | 0.00491782 |
| C1R | complement component 1, r subcomponent | 0.00491609 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00490694 |
| CBX6 | chromobox homolog 6 | 0.00488927 |
| ZNF217 | zinc finger protein 217 | 0.00488354 |
| HYOU1 | hypoxia up-regulated 1 | 0.00487604 |
| LMNB1 | lamin B1 | 0.0048746 |
| ADIPOR2 | adiponectin receptor 2 | 0.0048609 |
| DVL3 | dishevelled segment polarity protein 3 | 0.00484761 |
| FAAP100 | FA core complex associated protein 100 | 0.00484385 |
| SC5D | sterol-C5-desaturase | 0.00483982 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.0048343 |
| FABP6 | fatty acid binding protein 6, ileal | 0.00482681 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.00480795 |
| TUBG1 | tubulin, gamma 1 | 0.00478322 |
| SNX10 | sorting nexin 10 | 0.00478186 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.004773 |
| PRKCZ | protein kinase C, zeta | 0.00477112 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.00475836 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.00475452 |
| DVL1 | dishevelled segment polarity protein 1 | 0.00475278 |
| TEX2 | testis expressed 2 | 0.00475267 |
| TES | testin LIM domain protein | 0.00474518 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00473482 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00473217 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00472789 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.00472705 |
| ADCY3 | adenylate cyclase 3 | 0.00471557 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.00471537 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00470999 |
| MOK | MOK protein kinase | 0.00470782 |
| FERMT2 | fermitin family member 2 | 0.00469464 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00469295 |
| CENPB | centromere protein B, 80kDa | 0.00469001 |
| TRIB2 | tribbles pseudokinase 2 | 0.00467811 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.00466291 |
| SEC24C | SEC24 family member C | 0.00465351 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.00464684 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00462554 |
| TGFB1 | transforming growth factor, beta 1 | 0.00461943 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00461045 |
| ETV5 | ets variant 5 | 0.00459853 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 0.00459249 |
| CPE | carboxypeptidase E | 0.00458329 |
| MRTFB | myocardin related transcription factor B | 0.00458047 |
| SMTN | smoothelin | 0.00456805 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.00456415 |
| DKC1 | dyskeratosis congenita 1, dyskerin | 0.00454785 |
| ATG4B | autophagy related 4B, cysteine peptidase | 0.00454075 |
| NOTCH3 | notch 3 | 0.00453989 |
| SOCS1 | suppressor of cytokine signaling 1 | 0.00453614 |
| WWC1 | WW and C2 domain containing 1 | 0.00453047 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.00453033 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.00452913 |
| FLNA | filamin A, alpha | 0.00452521 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00451496 |
| SDC4 | syndecan 4 | 0.00451464 |
| EMP2 | epithelial membrane protein 2 | 0.00451436 |
| POLD2 | polymerase (DNA directed), delta 2, accessory subunit | 0.00451209 |
| PFKM | phosphofructokinase, muscle | 0.00450005 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | 0.00449902 |
| TRIP10 | thyroid hormone receptor interactor 10 | 0.00449512 |
| TRIP13 | thyroid hormone receptor interactor 13 | 0.00449418 |
| ITGAV | integrin, alpha V | 0.00449191 |
| ACVR1B | activin A receptor, type IB | 0.00448964 |
| MOGS | mannosyl-oligosaccharide glucosidase | 0.00448772 |
| HPCAL1 | hippocalcin-like 1 | 0.00448586 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 0.00448356 |
| SRPRA | SRP receptor subunit alpha | 0.00447948 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00447112 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) | 0.00446027 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa | 0.00445647 |
| FOXA1 | forkhead box A1 | 0.00445578 |
| CCNF | cyclin F | 0.00444971 |
| ATG9A | autophagy related 9A | 0.00444967 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.00444269 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) | 0.00442952 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.00442605 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00442512 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00441973 |
| KLHDC2 | kelch domain containing 2 | 0.00441895 |
| ZNF266 | zinc finger protein 266 | 0.0044124 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00440844 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00440613 |
| TLN1 | talin 1 | 0.00440476 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | 0.00440426 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.00440348 |
| INSIG2 | insulin induced gene 2 | 0.00439321 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00439146 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 | 0.00438888 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.014442 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0131322 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.0124274 |
| XIC | X chromosome inactivation center | -0.0123469 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0119516 |
| AOC1 | amine oxidase, copper containing 1 | -0.0115316 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0107797 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.0103549 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0103172 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00993159 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00940965 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00924672 |
| THBS1 | thrombospondin 1 | -0.00917496 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00911969 |
| HOPX | HOP homeobox | -0.00909832 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00898996 |
| KRT20 | keratin 20, type I | -0.00878737 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00874267 |
| KLF6 | Kruppel-like factor 6 | -0.00874002 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0087021 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00857493 |
| TXN | thioredoxin | -0.00839874 |
| TSPAN1 | tetraspanin 1 | -0.00819724 |
| FCGBP | Fc fragment of IgG binding protein | -0.0081758 |
| FAIM | Fas apoptotic inhibitory molecule | -0.00812765 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00812066 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00805099 |
| LY96 | lymphocyte antigen 96 | -0.00802726 |
| NMRK1 | nicotinamide riboside kinase 1 | -0.00800783 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.0079856 |
| MEG3 | maternally expressed 3 (non-protein coding) | -0.00791522 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00781344 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00780141 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00779392 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.0077327 |
| ZNF160 | zinc finger protein 160 | -0.00764214 |
| CLCA1 | chloride channel accessory 1 | -0.0076151 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00759504 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00748531 |
| LXN | latexin | -0.00744323 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | -0.00735158 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00714656 |
| TOR1A | torsin family 1, member A (torsin A) | -0.00711849 |
| WDR7 | WD repeat domain 7 | -0.00705931 |
| EGR3 | early growth response 3 | -0.00705818 |
| WASHC4 | WASH complex subunit 4 | -0.00700472 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00697406 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00696497 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00693834 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0069265 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00691816 |
| CA12 | carbonic anhydrase XII | -0.00685873 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -0.00685859 |
| S100A10 | S100 calcium binding protein A10 | -0.00682164 |
| IFI44L | interferon-induced protein 44-like | -0.00681444 |
| ADM | adrenomedullin | -0.00681437 |
| ASS1 | argininosuccinate synthase 1 | -0.00681228 |
| ZNF721 | zinc finger protein 721 | -0.00681077 |
| TEX10 | testis expressed 10 | -0.00680118 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -0.00676656 |
| ANXA1 | annexin A1 | -0.00675707 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00669567 |
| RGS4 | regulator of G-protein signaling 4 | -0.00662594 |
| MVP | major vault protein | -0.00654819 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00651156 |
| KRT1 | keratin 1, type II | -0.00648698 |
| LEFTY1 | left-right determination factor 1 | -0.00647805 |
| VNN1 | vanin 1 | -0.0064695 |
| DAPK1 | death-associated protein kinase 1 | -0.00640025 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00638763 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | -0.00635595 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00630275 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00627417 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00619811 |
| S100P | S100 calcium binding protein P | -0.0061595 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00613944 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00613855 |
| CCN2 | cellular communication network factor 2 | -0.00613718 |
| GPX1 | glutathione peroxidase 1 | -0.00613234 |
| MGST3 | microsomal glutathione S-transferase 3 | -0.00609025 |
| PYCARD | PYD and CARD domain containing | -0.00608007 |
| PITX3 | paired-like homeodomain 3 | -0.00606345 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00605671 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.00605379 |
| HSBP1 | heat shock factor binding protein 1 | -0.0060121 |
| S100A11 | S100 calcium binding protein A11 | -0.00599173 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00596809 |
| ZNF611 | zinc finger protein 611 | -0.00595762 |
| NRCAM | neuronal cell adhesion molecule | -0.00595247 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00594374 |
| CAPN3 | calpain 3, (p94) | -0.00592573 |
| ZG16 | zymogen granule protein 16 | -0.0058908 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00588989 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.00588068 |
| TBCA | tubulin folding cofactor A | -0.005866 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00586437 |
| SH3BGR | SH3 domain binding glutamate-rich protein | -0.00584779 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00584507 |
| RPS27L | ribosomal protein S27-like | -0.00583408 |
| MYOF | myoferlin | -0.00581697 |
| HAL | histidine ammonia-lyase | -0.00581025 |
| CLEC2B | C-type lectin domain family 2, member B | -0.0057897 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.00578409 |
| PRR11 | proline rich 11 | -0.00576632 |
| ATP5MF | ATP synthase membrane subunit f | -0.00576137 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00575947 |
| ATP5MJ | ATP synthase membrane subunit j | -0.00575481 |
| TMEM176B | transmembrane protein 176B | -0.00575425 |
| STK10 | serine/threonine kinase 10 | -0.00574987 |
| TMEM176A | transmembrane protein 176A | -0.00574778 |
| BMP4 | bone morphogenetic protein 4 | -0.00572039 |
| EVI2A | ecotropic viral integration site 2A | -0.00571644 |
| PDGFD | platelet derived growth factor D | -0.00569829 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00566335 |
| NAV3 | neuron navigator 3 | -0.00563396 |
| TMEM14A | transmembrane protein 14A | -0.00563066 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00562881 |
| TLR4 | toll-like receptor 4 | -0.00562528 |
| FBXO11 | F-box protein 11 | -0.0056083 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -0.00559602 |
| OPHN1 | oligophrenin 1 | -0.00558743 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00557218 |
| PFDN4 | prefoldin subunit 4 | -0.00556347 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00554248 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00553817 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00553171 |
| LPXN | leupaxin | -0.00551964 |
| ECM1 | extracellular matrix protein 1 | -0.00548078 |
| COL1A2 | collagen, type I, alpha 2 | -0.00545929 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00544717 |
| LRRC17 | leucine rich repeat containing 17 | -0.00543106 |
| OPTN | optineurin | -0.00543097 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.00542965 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00540994 |
| SLN | sarcolipin | -0.00539146 |
| TNNC1 | troponin C type 1 (slow) | -0.00538781 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00537848 |
| RABAC1 | Rab acceptor 1 (prenylated) | -0.00537659 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00537175 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00537159 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | -0.00535117 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0053259 |
| TRIM22 | tripartite motif containing 22 | -0.00532258 |
| FBN2 | fibrillin 2 | -0.00531906 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00529462 |
| ATF3 | activating transcription factor 3 | -0.00529011 |
| JAM3 | junctional adhesion molecule 3 | -0.00528533 |
| UPP1 | uridine phosphorylase 1 | -0.00526211 |
| PLP1 | proteolipid protein 1 | -0.00522971 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | -0.0052242 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00521612 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | -0.00521369 |
| BTNL8 | butyrophilin-like 8 | -0.00519705 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | -0.00518404 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00516321 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | -0.00514475 |
| INSM1 | insulinoma-associated 1 | -0.00512684 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.0051164 |
| CD52 | CD52 molecule | -0.00510849 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00510516 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00508999 |
| CWH43 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) | -0.00506995 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | -0.0050617 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00504483 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00503811 |
| PERP | PERP, TP53 apoptosis effector | -0.00503313 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.00500316 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00500291 |
| SALL1 | spalt-like transcription factor 1 | -0.00499993 |
| TMEM47 | transmembrane protein 47 | -0.00499656 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00499481 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | -0.00499184 |
| MIR22HG | MIR22 host gene | -0.00496193 |
| THBS4 | thrombospondin 4 | -0.0049567 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.00494998 |
| EDF1 | endothelial differentiation-related factor 1 | -0.00494853 |
| CLCA4 | chloride channel accessory 4 | -0.00493706 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.00492561 |
| WASL | Wiskott-Aldrich syndrome-like | -0.00492062 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | -0.00490496 |
| AQP8 | aquaporin 8 | -0.00489885 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00488801 |
| ZIC1 | Zic family member 1 | -0.00488516 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.0048804 |
| STMN2 | stathmin 2 | -0.00487219 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00486243 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00485448 |
| CNTN1 | contactin 1 | -0.00484139 |
| OSTF1 | osteoclast stimulating factor 1 | -0.00483831 |
| NDUFB2 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa | -0.00483474 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00483302 |
| IRF6 | interferon regulatory factor 6 | -0.00483053 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00482172 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00482026 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 | -0.00481892 |
| ACAA2 | acetyl-CoA acyltransferase 2 | -0.00481781 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00480748 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00479316 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00478834 |
| NOX1 | NADPH oxidase 1 | -0.00475212 |
| CIAO2B | cytosolic iron-sulfur assembly component 2B | -0.00475123 |
| MAP7 | microtubule-associated protein 7 | -0.00474792 |
| CALB1 | calbindin 1, 28kDa | -0.00474775 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | -0.00474246 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00473591 |
| CDO1 | cysteine dioxygenase type 1 | -0.00472415 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00471801 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00471416 |
| MRPS33 | mitochondrial ribosomal protein S33 | -0.00470925 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00470707 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00470334 |
| MYOZ2 | myozenin 2 | -0.00469796 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.00469463 |
| PEG3 | paternally expressed 3 | -0.00468946 |
| NANOG | Nanog homeobox | -0.00468811 |
| PLS3 | plastin 3 | -0.00468424 |
| MEF2C | myocyte enhancer factor 2C | -0.00467698 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00466625 |
| PSG5 | pregnancy specific beta-1-glycoprotein 5 | -0.00465918 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00464673 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.00464285 |
| SPP1 | secreted phosphoprotein 1 | -0.00464217 |
| NXPE4 | neurexophilin and PC-esterase domain family, member 4 | -0.00463272 |
| CPM | carboxypeptidase M | -0.00462561 |
| TOX | thymocyte selection-associated high mobility group box | -0.00462414 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) | -0.00462272 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00461949 |
| LRRC31 | leucine rich repeat containing 31 | -0.00461445 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00459946 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.00459816 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.00459708 |
| ASPA | aspartoacylase | -0.00458873 |
| CLDND1 | claudin domain containing 1 | -0.00458795 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00458712 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.00458126 |
| FAM198B | family with sequence similarity 198, member B | -0.00456356 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00455713 |
| ZNF277 | zinc finger protein 277 | -0.00455706 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | -0.00454763 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00454652 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | -0.00454247 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 | -0.00453582 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | -0.00453551 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | -0.00452434 |
| COX5B | cytochrome c oxidase subunit Vb | -0.00452379 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00451873 |
| SLC35G2 | solute carrier family 35, member G2 | -0.0045184 |
| ENDOD1 | endonuclease domain containing 1 | -0.00451007 |
| ITM2C | integral membrane protein 2C | -0.00449886 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00449525 |
