CD247 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description CD247 molecule|The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 919)
External Link https://ncbi.nlm.nih.gov/gene/919
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Genes

498 genes differentially expressed following the CD247 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0228178
BEX1 brain expressed, X-linked 1 0.018396
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.018024
XPO7 exportin 7 0.0166776
TFDP1 transcription factor Dp-1 0.0142048
CXCL12 chemokine (C-X-C motif) ligand 12 0.0140772
LOXL1 lysyl oxidase-like 1 0.0138232
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0127582
NRN1 neuritin 1 0.0125083
SFRP1 secreted frizzled-related protein 1 0.0120084
CD200 CD200 molecule 0.0119141
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.0119074
PLAT plasminogen activator, tissue 0.0117816
DPYSL3 dihydropyrimidinase-like 3 0.0116972
ACAT2 acetyl-CoA acetyltransferase 2 0.0115081
EXOC5 exocyst complex component 5 0.0114433
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.0113307
FABP7 fatty acid binding protein 7, brain 0.0113133
ASCL1 achaete-scute family bHLH transcription factor 1 0.0112413
AK4 adenylate kinase 4 0.0112168
CCNA2 cyclin A2 0.0111917
KDM5D lysine (K)-specific demethylase 5D 0.0110151
KIF20A kinesin family member 20A 0.0109439
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.0106398
C3ORF14 chromosome 3 open reading frame 14 0.0106058
COL1A2 collagen, type I, alpha 2 0.0105651
TIMP3 TIMP metallopeptidase inhibitor 3 0.0105629
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.0104909
HMGB3 high mobility group box 3 0.0102962
SCAMP1 secretory carrier membrane protein 1 0.0102798
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.0101985
C7 complement component 7 0.00996927
PRKD3 protein kinase D3 0.00994238
CPVL carboxypeptidase, vitellogenic-like 0.00992982
ERLIN2 ER lipid raft associated 2 0.00990899
ANOS1 anosmin 1 0.00980278
DPYD dihydropyrimidine dehydrogenase 0.0097913
ITM2A integral membrane protein 2A 0.00966867
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00947457
PLSCR4 phospholipid scramblase 4 0.00945005
GPC3 glypican 3 0.00940822
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00934857
LTA4H leukotriene A4 hydrolase 0.00928518
NTS neurotensin 0.00927218
ADGRL2 adhesion G protein-coupled receptor L2 0.00920391
RGS5 regulator of G-protein signaling 5 0.00916585
BIRC5 baculoviral IAP repeat containing 5 0.00904219
CXADR coxsackie virus and adenovirus receptor 0.00901504
SRSF1 serine/arginine-rich splicing factor 1 0.00900399
GTPBP8 GTP-binding protein 8 (putative) 0.00898446
DHFR dihydrofolate reductase 0.00898315
FMO2 flavin containing monooxygenase 2 (non-functional) 0.00884798
SLC35A5 solute carrier family 35, member A5 0.00880377
NREP neuronal regeneration related protein 0.00878225
F2R coagulation factor II (thrombin) receptor 0.0086986
PTPRD protein tyrosine phosphatase, receptor type, D 0.00864876
NOVA1 neuro-oncological ventral antigen 1 0.008628
CPE carboxypeptidase E 0.00862593
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00862164
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.00861604
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00860164
MAGEA3 melanoma antigen family A3 0.00859625
RPA3 replication protein A3, 14kDa 0.0085959
ALDOC aldolase C, fructose-bisphosphate 0.00854257
GCA grancalcin, EF-hand calcium binding protein 0.00853156
ENO1 enolase 1, (alpha) 0.00851864
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00849184
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00845718
FCGBP Fc fragment of IgG binding protein 0.00844817
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.00844781
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.00844751
SEPP1 selenoprotein P, plasma, 1 0.00840402
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00837532
TMEM38B transmembrane protein 38B 0.00834688
DIPK1A divergent protein kinase domain 1A 0.00828718
PLPBP pyridoxal phosphate binding protein 0.00828642
BHLHE41 basic helix-loop-helix family, member e41 0.00828088
FHL1 four and a half LIM domains 1 0.00827683
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.00825176
NPY1R neuropeptide Y receptor Y1 0.00820868
EGR2 early growth response 2 0.00818889
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 0.00818284
SPRED2 sprouty-related, EVH1 domain containing 2 0.00811785
PLN phospholamban 0.00811709
COL3A1 collagen, type III, alpha 1 0.00807873
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00807602
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00804915
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.00804109
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00803572
MRPL39 mitochondrial ribosomal protein L39 0.00801098
TYRP1 tyrosinase-related protein 1 0.0079939
BCHE butyrylcholinesterase 0.00797721
LIG1 ligase I, DNA, ATP-dependent 0.00795319
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.00791426
IFRD2 interferon-related developmental regulator 2 0.00787846
TMEM47 transmembrane protein 47 0.00786595
EML4 echinoderm microtubule associated protein like 4 0.00786165
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00784607
PDHB pyruvate dehydrogenase (lipoamide) beta 0.00782518
MEN1 multiple endocrine neoplasia I 0.00780117
CXCL14 chemokine (C-X-C motif) ligand 14 0.00779512
IPO5 importin 5 0.00779326
CA9 carbonic anhydrase IX 0.00778818
COPS4 COP9 signalosome subunit 4 0.00775893
DZIP1 DAZ interacting zinc finger protein 1 0.00774356
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.00771649
TDP1 tyrosyl-DNA phosphodiesterase 1 0.00767161
DMD dystrophin 0.00764827
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.00759138
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.00758941
CDC42 cell division cycle 42 0.00758781
LDB2 LIM domain binding 2 0.00758451
SALL2 spalt-like transcription factor 2 0.00755363
RBBP4 retinoblastoma binding protein 4 0.00751952
FGFR3 fibroblast growth factor receptor 3 0.00748638
PER3 period circadian clock 3 0.00748575
AMD1 adenosylmethionine decarboxylase 1 0.00748365
RTN1 reticulon 1 0.00747348
TRMT5 tRNA methyltransferase 5 0.00743676
NUBPL nucleotide binding protein-like 0.00743216
PCYOX1 prenylcysteine oxidase 1 0.00742262
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00741753
PBK PDZ binding kinase 0.00740936
PCYOX1L prenylcysteine oxidase 1 like 0.00739163
SET SET nuclear proto-oncogene 0.00737905
PTTG1 pituitary tumor-transforming 1 0.00737836
POSTN periostin, osteoblast specific factor 0.00736182
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00736094
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00735295
DCTN4 dynactin 4 (p62) 0.00733331
CDCA4 cell division cycle associated 4 0.00732233
PRR5L proline rich 5 like 0.00731929
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.00731855
FAM216A family with sequence similarity 216, member A 0.00730084
C1QBP complement component 1, q subcomponent binding protein 0.00728424
CCND2 cyclin D2 0.00728216
USP9Y ubiquitin specific peptidase 9, Y-linked 0.00724042
TRIP13 thyroid hormone receptor interactor 13 0.00723511
COMMD10 COMM domain containing 10 0.00722961
BNC2 basonuclin 2 0.00722715
BMPR1A bone morphogenetic protein receptor, type IA 0.0072017
FAR2 fatty acyl CoA reductase 2 0.0072014
CD300A CD300a molecule 0.00719568
PRUNE2 prune homolog 2 (Drosophila) 0.00717662
ALG8 ALG8, alpha-1,3-glucosyltransferase 0.00717642
TMEM176A transmembrane protein 176A 0.00716408
NANOG Nanog homeobox 0.00715831
RGS1 regulator of G-protein signaling 1 0.00714662
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.0071422
ICMT isoprenylcysteine carboxyl methyltransferase 0.00713673
SUB1 SUB1 homolog (S. cerevisiae) 0.00712885
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.00710865
BCL2 B-cell CLL/lymphoma 2 0.00710445
ACE2 angiotensin I converting enzyme 2 0.00710321
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00709763
SMC2 structural maintenance of chromosomes 2 0.00708838
RET ret proto-oncogene 0.00708641
CAND1 cullin-associated and neddylation-dissociated 1 0.00708509
SPTSSA serine palmitoyltransferase, small subunit A 0.00706866
DPY19L2P2 DPY19L2 pseudogene 2 0.00705577
CCKBR cholecystokinin B receptor 0.00705396
REEP1 receptor accessory protein 1 0.00704376
DLAT dihydrolipoamide S-acetyltransferase 0.00703927
NCAPD3 non-SMC condensin II complex, subunit D3 0.00703526
SRSF7 serine/arginine-rich splicing factor 7 0.00703071
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00701085
TSPAN6 tetraspanin 6 0.00700078
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00697552
HOPX HOP homeobox 0.0069718
PDE4B phosphodiesterase 4B, cAMP-specific 0.00695325
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00693951
RAB23 RAB23, member RAS oncogene family 0.00693802
EIF4E eukaryotic translation initiation factor 4E 0.00693232
CDKN3 cyclin-dependent kinase inhibitor 3 0.00692522
EXD2 exonuclease 3'-5' domain containing 2 0.00689446
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.00688948
TUBB2A tubulin, beta 2A class IIa 0.00688647
KIF15 kinesin family member 15 0.00687334
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.00686792
FBLN5 fibulin 5 0.00685818
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.00684479
NLGN4X neuroligin 4, X-linked 0.00684046
PRMT2 protein arginine methyltransferase 2 0.00683805
DLD dihydrolipoamide dehydrogenase 0.00681606
NEBL nebulette 0.00681558
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.00680492
YEATS4 YEATS domain containing 4 0.00679744
A2M alpha-2-macroglobulin 0.00679379
PRC1 protein regulator of cytokinesis 1 0.00679012
THAP12 THAP domain containing 12 0.00678514
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00676544
PCLAF PCNA clamp associated factor 0.00676403
KLHL23 kelch-like family member 23 0.00676287
DUT deoxyuridine triphosphatase 0.00675312
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.00674863
MDFIC MyoD family inhibitor domain containing 0.00674677
C21ORF33 chromosome 21 open reading frame 33 0.00673456
ADAMTSL3 ADAMTS-like 3 0.00671624
PRKD1 protein kinase D1 0.00669569
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00668301
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 0.00667022
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.00666315
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00666274
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00666189
MTARC1 mitochondrial amidoxime reducing component 1 0.00664283
ETV1 ets variant 1 0.00664173
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.00663971
ADGRF5 adhesion G protein-coupled receptor F5 0.00661987
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00659499
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00657844
CDC7 cell division cycle 7 0.00657745
SEC23A Sec23 homolog A (S. cerevisiae) 0.00655756
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00655381
PTDSS1 phosphatidylserine synthase 1 0.00655041
AFP alpha-fetoprotein 0.00653899
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00652691
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 0.00652167
LMNB1 lamin B1 0.00650286
B3GNT1 0.00649932
SELL selectin L 0.00649523
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.00649275
GSTA4 glutathione S-transferase alpha 4 0.00649258
NFASC neurofascin 0.00648727
FMO1 flavin containing monooxygenase 1 0.00648277
CDK1 cyclin-dependent kinase 1 0.00646199
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00644971
DMAC2L distal membrane arm assembly component 2 like 0.00644557
CADPS2 Ca++-dependent secretion activator 2 0.00644514
PADI2 peptidyl arginine deiminase, type II 0.00644348
LMAN1 lectin, mannose-binding, 1 0.00643867
GPM6A glycoprotein M6A 0.00643048
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.00641369
TFF1 trefoil factor 1 0.00639985
CENPE centromere protein E, 312kDa 0.00639674
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00638544
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.00638284
KIF1B kinesin family member 1B 0.00636946
CANX calnexin 0.00636877
PLS3 plastin 3 0.00636509
LRP2 low density lipoprotein receptor-related protein 2 0.00635913
SIVA1 SIVA1, apoptosis-inducing factor 0.00635685
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.00634905
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00634533
NUP107 nucleoporin 107kDa 0.00634273
MAT2A methionine adenosyltransferase II, alpha 0.00633883
PDLIM3 PDZ and LIM domain 3 0.00633821
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.0063344
C9ORF40 chromosome 9 open reading frame 40 0.0063324
FANCL Fanconi anemia, complementation group L 0.00633062

decreased expression

Symbol Name Standardized Value
HSPA1A heat shock 70kDa protein 1A -0.0234911
HSPB1 heat shock 27kDa protein 1 -0.0232302
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0182385
IFI6 interferon, alpha-inducible protein 6 -0.0161456
XIC X chromosome inactivation center -0.0156141
ISG15 ISG15 ubiquitin-like modifier -0.0153823
METRN meteorin, glial cell differentiation regulator -0.0151342
MX1 MX dynamin-like GTPase 1 -0.0147492
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0144467
PERP PERP, TP53 apoptosis effector -0.0144401
JCHAIN joining chain of multimeric IgA and IgM -0.0141358
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.0139552
HMOX1 heme oxygenase 1 -0.013931
MT1X metallothionein 1X -0.0136801
BIK BCL2-interacting killer (apoptosis-inducing) -0.0134886
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0132956
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.013129
CLU clusterin -0.0128376
PLAAT3 phospholipase A and acyltransferase 3 -0.012535
MVP major vault protein -0.0124764
DSP desmoplakin -0.0123506
AMDHD2 amidohydrolase domain containing 2 -0.0120702
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.011814
POU2AF1 POU class 2 associating factor 1 -0.0114433
IFI27 interferon, alpha-inducible protein 27 -0.0114344
PLK1 polo-like kinase 1 -0.0112936
VAMP8 vesicle-associated membrane protein 8 -0.0112677
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0112049
MT1G metallothionein 1G -0.0111895
TGFBI transforming growth factor, beta-induced, 68kDa -0.0111574
SLC38A1 solute carrier family 38, member 1 -0.0111298
GADD45A growth arrest and DNA-damage-inducible, alpha -0.0109656
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0109106
TPD52L1 tumor protein D52-like 1 -0.0108451
ATF3 activating transcription factor 3 -0.0108338
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.0107703
FKBP11 FK506 binding protein 11, 19 kDa -0.010615
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.010566
BMP4 bone morphogenetic protein 4 -0.0105345
RND3 Rho family GTPase 3 -0.0104662
OSR2 odd-skipped related transciption factor 2 -0.0104086
CFB complement factor B -0.0103925
LCN2 lipocalin 2 -0.0103268
RRAGD Ras-related GTP binding D -0.0102891
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.010265
TGM2 transglutaminase 2 -0.0102515
FTH1 ferritin, heavy polypeptide 1 -0.0102254
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.0101995
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.010124
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.0101173
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.010085
BTG1 B-cell translocation gene 1, anti-proliferative -0.00992985
APOD apolipoprotein D -0.00992338
KRT14 keratin 14, type I -0.00991406
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00974767
IRF7 interferon regulatory factor 7 -0.00958603
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00956516
AKAP9 A kinase (PRKA) anchor protein 9 -0.00955992
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.00954116
STC2 stanniocalcin 2 -0.00953555
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00952659
IL1R1 interleukin 1 receptor, type I -0.00947658
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00943241
ASS1 argininosuccinate synthase 1 -0.00938351
DDIT3 DNA-damage-inducible transcript 3 -0.00937405
MZB1 marginal zone B and B1 cell-specific protein -0.0093541
BST2 bone marrow stromal cell antigen 2 -0.00929583
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00923873
MT1M metallothionein 1M -0.00923243
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00917661
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00917204
PAX5 paired box 5 -0.00915021
MT1E metallothionein 1E -0.00912369
ECM1 extracellular matrix protein 1 -0.00909159
RHOD ras homolog family member D -0.00893213
JUNB jun B proto-oncogene -0.00889084
IRS2 insulin receptor substrate 2 -0.00885731
HSPA2 heat shock 70kDa protein 2 -0.00881464
ZNF91 zinc finger protein 91 -0.00880916
TPSAB1 tryptase alpha/beta 1 -0.00878047
VGLL4 vestigial-like family member 4 -0.00875258
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00875147
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00869845
ADIRF adipogenesis regulatory factor -0.00863717
PLK2 polo-like kinase 2 -0.00858109
IL32 interleukin 32 -0.00844851
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -0.00840018
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00839731
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00837498
TNIP1 TNFAIP3 interacting protein 1 -0.00832753
PMP22 peripheral myelin protein 22 -0.0083088
CCN3 cellular communication network factor 3 -0.00830657
FOXO1 forkhead box O1 -0.00829754
KLHL24 kelch-like family member 24 -0.00826359
KLK11 kallikrein-related peptidase 11 -0.00824354
TRIB1 tribbles pseudokinase 1 -0.00819176
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00816983
CPA3 carboxypeptidase A3 (mast cell) -0.00811489
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00805638
PDLIM4 PDZ and LIM domain 4 -0.00801353
QPRT quinolinate phosphoribosyltransferase -0.00801345
MCOLN1 mucolipin 1 -0.00800737
PLXNB2 plexin B2 -0.00800187
MT1H metallothionein 1H -0.00800133
CD9 CD9 molecule -0.00799463
TYMP thymidine phosphorylase -0.00798245
ISG20 interferon stimulated exonuclease gene 20kDa -0.00792377
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00791577
BRD4 bromodomain containing 4 -0.00791014
CTSA cathepsin A -0.00787738
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00786486
SOD2 superoxide dismutase 2, mitochondrial -0.00785559
IER5 immediate early response 5 -0.00785421
OASL 2'-5'-oligoadenylate synthetase-like -0.00785298
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00782198
IRF9 interferon regulatory factor 9 -0.00782099
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00780242
SMAD3 SMAD family member 3 -0.0077966
SIK1 salt-inducible kinase 1 -0.00778476
TPD52L2 tumor protein D52-like 2 -0.00774413
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00774378
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00773448
TCL1A T-cell leukemia/lymphoma 1A -0.00771408
RRAGC Ras-related GTP binding C -0.00769097
ABHD3 abhydrolase domain containing 3 -0.00768511
LRP4 low density lipoprotein receptor-related protein 4 -0.0076758
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00766918
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00765118
PLEC plectin -0.00764259
EIF5B eukaryotic translation initiation factor 5B -0.00763531
SFN stratifin -0.0076164
ALOX5 arachidonate 5-lipoxygenase -0.00758888
MICB MHC class I polypeptide-related sequence B -0.00758756
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -0.00756978
H1-0 H1.0 linker histone -0.00755892
HIST1H2BD histone cluster 1, H2bd -0.00754988
SLC16A6 solute carrier family 16, member 6 -0.00754953
IFI35 interferon-induced protein 35 -0.00754704
DUSP5 dual specificity phosphatase 5 -0.00754151
NXN nucleoredoxin -0.00753567
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00751949
NEU1 sialidase 1 (lysosomal sialidase) -0.00751834
RAB13 RAB13, member RAS oncogene family -0.00751739
HIST1H2AE histone cluster 1, H2ae -0.00750579
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00749959
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00749722
CHN1 chimerin 1 -0.00748846
PENK proenkephalin -0.00748304
LEF1 lymphoid enhancer-binding factor 1 -0.00747056
ENAH enabled homolog (Drosophila) -0.00744844
CCNG2 cyclin G2 -0.00744501
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00743823
LTBP2 latent transforming growth factor beta binding protein 2 -0.00743562
MT1F metallothionein 1F -0.00743246
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.00742391
SPON2 spondin 2, extracellular matrix protein -0.00741246
MGLL monoglyceride lipase -0.00739183
DDIT4 DNA-damage-inducible transcript 4 -0.00739116
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00739073
IFI44L interferon-induced protein 44-like -0.00738293
DLX5 distal-less homeobox 5 -0.00737658
CYB5R1 cytochrome b5 reductase 1 -0.00736251
CD79A CD79a molecule, immunoglobulin-associated alpha -0.00735628
RNF6 ring finger protein (C3H2C3 type) 6 -0.00733982
RIN2 Ras and Rab interactor 2 -0.00729945
LHFPL2 lipoma HMGIC fusion partner-like 2 -0.00727815
CLCN7 chloride channel, voltage-sensitive 7 -0.00727742
PYCARD PYD and CARD domain containing -0.00726653
CD19 CD19 molecule -0.00726056
HIST2H2BE histone cluster 2, H2be -0.00723626
BLNK B-cell linker -0.00722465
PRSS8 protease, serine, 8 -0.00722315
GPR137B G protein-coupled receptor 137B -0.00721116
COMT catechol-O-methyltransferase -0.00720929
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.00720487
TGFB1 transforming growth factor, beta 1 -0.00719725
FADS3 fatty acid desaturase 3 -0.00718964
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -0.00718452
SQSTM1 sequestosome 1 -0.00718186
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00717596
PXDC1 PX domain containing 1 -0.00716969
ZNF394 zinc finger protein 394 -0.00715775
H1-2 H1.2 linker histone, cluster member -0.0071493
ARL8B ADP-ribosylation factor-like 8B -0.00714689
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.0071424
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -0.00713159
YBX3 Y box binding protein 3 -0.00713041
LIMS1 LIM and senescent cell antigen-like domains 1 -0.00712807
HBD hemoglobin, delta -0.00711579
C9ORF16 chromosome 9 open reading frame 16 -0.00709034
S100P S100 calcium binding protein P -0.00708987
SRCAP Snf2-related CREBBP activator protein -0.00708952
TAPBP TAP binding protein (tapasin) -0.00708638
HIST1H2AC histone cluster 1, H2ac -0.00707607
TOB1 transducer of ERBB2, 1 -0.00707497
TPD52 tumor protein D52 -0.00704728
TSC22D1 TSC22 domain family, member 1 -0.00703839
REG1A regenerating islet-derived 1 alpha -0.00702776
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -0.00701629
MMP7 matrix metallopeptidase 7 -0.00699182
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -0.00697838
TPST2 tyrosylprotein sulfotransferase 2 -0.00697327
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -0.00694905
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00694622
OFD1 oral-facial-digital syndrome 1 -0.00690981
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 -0.00690476
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A -0.00685933
NCDN neurochondrin -0.00684482
FSTL3 follistatin-like 3 (secreted glycoprotein) -0.0068369
USP18 ubiquitin specific peptidase 18 -0.00682935
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00682576
IGF2R insulin-like growth factor 2 receptor -0.00681436
KRT17 keratin 17, type I -0.0068131
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -0.00681121
CLIC3 chloride intracellular channel 3 -0.00680331
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00677641
RAB9A RAB9A, member RAS oncogene family -0.00677187
ATF4 activating transcription factor 4 -0.00675496
RHOF ras homolog family member F (in filopodia) -0.00674071
IL1RN interleukin 1 receptor antagonist -0.00673792
XAF1 XIAP associated factor 1 -0.00672264
SEPHS2 selenophosphate synthetase 2 -0.00671565
HGD homogentisate 1,2-dioxygenase -0.00670329
CFD complement factor D (adipsin) -0.00668593
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00667558
MYO10 myosin X -0.00667463
SNAP23 synaptosomal-associated protein, 23kDa -0.00666397
ABHD4 abhydrolase domain containing 4 -0.00664278
NT5E 5'-nucleotidase, ecto (CD73) -0.00662791
RBM47 RNA binding motif protein 47 -0.00662352
CHMP4A charged multivesicular body protein 4A -0.00662285
ATF7IP activating transcription factor 7 interacting protein -0.00660659
CLN3 ceroid-lipofuscinosis, neuronal 3 -0.00660559
MT1HL1 metallothionein 1H-like 1 -0.0066014
EGR1 early growth response 1 -0.00659741
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.00658845
UPP1 uridine phosphorylase 1 -0.00658628
COL7A1 collagen, type VII, alpha 1 -0.00657795
ZSWIM8 zinc finger, SWIM-type containing 8 -0.00656715
CNOT3 CCR4-NOT transcription complex, subunit 3 -0.00656609
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -0.0065574
OSBPL2 oxysterol binding protein-like 2 -0.00654259
MLPH melanophilin -0.00653577
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa -0.006522
MMP19 matrix metallopeptidase 19 -0.00652037
S100A11 S100 calcium binding protein A11 -0.00651309
BAD BCL2-associated agonist of cell death -0.00651206
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00648907
SH3BP4 SH3-domain binding protein 4 -0.00648904