| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | CD27 molecule|The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 939) |
| External Link | https://ncbi.nlm.nih.gov/gene/939 |
| Similar Terms | |
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499 genes differentially expressed following the CD27 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0294187 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.0169752 |
| MSMB | microseminoprotein, beta- | 0.014522 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0140191 |
| ASPN | asporin | 0.0136876 |
| NPY1R | neuropeptide Y receptor Y1 | 0.0134515 |
| ADIRF | adipogenesis regulatory factor | 0.0130888 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0127682 |
| GNAS | GNAS complex locus | 0.0125276 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.0123519 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.0120343 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.011764 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.011704 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0112256 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0106469 |
| ESR1 | estrogen receptor 1 | 0.0100386 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.0100339 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00996904 |
| KRT19 | keratin 19, type I | 0.00994505 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00994391 |
| TMEM255A | transmembrane protein 255A | 0.00989054 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00986297 |
| COPS7A | COP9 signalosome subunit 7A | 0.00985499 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00970613 |
| GPX1 | glutathione peroxidase 1 | 0.00942531 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00929563 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00926663 |
| PTN | pleiotrophin | 0.00924832 |
| OGN | osteoglycin | 0.00921491 |
| CP | ceruloplasmin (ferroxidase) | 0.00920012 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00896775 |
| LRRC17 | leucine rich repeat containing 17 | 0.00892651 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00890778 |
| FRZB | frizzled-related protein | 0.00890378 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00881379 |
| TCF4 | transcription factor 4 | 0.00872729 |
| ZNHIT1 | zinc finger, HIT-type containing 1 | 0.00863251 |
| THBS1 | thrombospondin 1 | 0.0086318 |
| KRT18 | keratin 18, type I | 0.0086244 |
| IFI44L | interferon-induced protein 44-like | 0.00857638 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00853325 |
| CTSK | cathepsin K | 0.00848052 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.008479 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00839496 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00826274 |
| XIC | X chromosome inactivation center | 0.0081506 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00815013 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00811077 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00805916 |
| TAGLN2 | transgelin 2 | 0.00792017 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0078948 |
| HOXB2 | homeobox B2 | 0.00788744 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00781446 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.00779342 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00777974 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00774738 |
| MMP1 | matrix metallopeptidase 1 | 0.00773231 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00772392 |
| EGR2 | early growth response 2 | 0.00769799 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00769629 |
| ATP5MF | ATP synthase membrane subunit f | 0.0076525 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.0075296 |
| MX1 | MX dynamin-like GTPase 1 | 0.00748971 |
| EMP1 | epithelial membrane protein 1 | 0.00748173 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00745059 |
| COL10A1 | collagen, type X, alpha 1 | 0.00744238 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00740932 |
| AREG | amphiregulin | 0.00738048 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00729218 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00727207 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00722968 |
| POP7 | processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) | 0.0072097 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00714466 |
| CHN1 | chimerin 1 | 0.00713816 |
| LHFP | lipoma HMGIC fusion partner | 0.00705164 |
| ALB | albumin | 0.00701773 |
| RGS5 | regulator of G-protein signaling 5 | 0.00700971 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00693652 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00686633 |
| KRT13 | keratin 13, type I | 0.0068119 |
| TEX10 | testis expressed 10 | 0.00678885 |
| MAGED2 | melanoma antigen family D2 | 0.00678323 |
| CD9 | CD9 molecule | 0.00677706 |
| HNMT | histamine N-methyltransferase | 0.00674404 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.0067292 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00666027 |
| SSPN | sarcospan | 0.00664843 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00662977 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00661309 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.0066006 |
| DAXX | death-domain associated protein | 0.0065308 |
| EDNRA | endothelin receptor type A | 0.00652834 |
| TMEM14B | transmembrane protein 14B | 0.0065141 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.00646633 |
| STK17A | serine/threonine kinase 17a | 0.00645823 |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 | 0.00644253 |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.00644025 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00641692 |
| C4BPA | complement component 4 binding protein, alpha | 0.00640872 |
| SSR4 | signal sequence receptor, delta | 0.00637764 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00637314 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00634911 |
| BLNK | B-cell linker | 0.00634657 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0063361 |
| GSPT2 | G1 to S phase transition 2 | 0.0063012 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00628578 |
| WDR45 | WD repeat domain 45 | 0.0062466 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00623997 |
| TSPAN13 | tetraspanin 13 | 0.00621656 |
| MUC16 | mucin 16, cell surface associated | 0.00621129 |
| SH2B3 | SH2B adaptor protein 3 | 0.00620551 |
| PLAT | plasminogen activator, tissue | 0.00620069 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.00617672 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00616988 |
| CXORF40B | chromosome X open reading frame 40B | 0.00616697 |
| GPR137B | G protein-coupled receptor 137B | 0.00615545 |
| NRBF2 | nuclear receptor binding factor 2 | 0.00614868 |
| PALLD | palladin, cytoskeletal associated protein | 0.00611992 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00610472 |
| PNMA8A | PNMA family member 8A | 0.00609765 |
| MMP13 | matrix metallopeptidase 13 | 0.00606907 |
| PCDH17 | protocadherin 17 | 0.00602655 |
| ELOVL2 | ELOVL fatty acid elongase 2 | 0.00602196 |
| GSN | gelsolin | 0.0060168 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00601595 |
| PRNP | prion protein | 0.00600792 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | 0.00600158 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00599788 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00595442 |
| SDC1 | syndecan 1 | 0.00595075 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00594737 |
| LPXN | leupaxin | 0.00592688 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.00592334 |
| CPB2 | carboxypeptidase B2 (plasma) | 0.00592065 |
| OMD | osteomodulin | 0.00588234 |
| SNX13 | sorting nexin 13 | 0.00587205 |
| RPA3 | replication protein A3, 14kDa | 0.00585838 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.00584555 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.00584429 |
| DCLK1 | doublecortin-like kinase 1 | 0.00584373 |
| CHGB | chromogranin B | 0.00584164 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0058382 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.005833 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00583147 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.00582925 |
| CHMP5 | charged multivesicular body protein 5 | 0.00581576 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00581482 |
| C3 | complement component 3 | 0.00579696 |
| HSBP1 | heat shock factor binding protein 1 | 0.00579655 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.00579605 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00579313 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.00579294 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 0.00578527 |
| MLF2 | myeloid leukemia factor 2 | 0.00577775 |
| GTF3A | general transcription factor IIIA | 0.00577155 |
| TSPAN1 | tetraspanin 1 | 0.00576549 |
| DUSP5 | dual specificity phosphatase 5 | 0.00574774 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00574265 |
| CXORF40A | chromosome X open reading frame 40A | 0.00573085 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.0057191 |
| PRRX1 | paired related homeobox 1 | 0.00571905 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00570536 |
| HMGN1 | high mobility group nucleosome binding domain 1 | 0.00570341 |
| IFNGR1 | interferon gamma receptor 1 | 0.00568808 |
| CNN3 | calponin 3, acidic | 0.00567425 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00567262 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.0056603 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.00563341 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | 0.00562635 |
| TMEM243 | transmembrane protein 243, mitochondrial | 0.00562241 |
| PAK1IP1 | PAK1 interacting protein 1 | 0.00562227 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00561247 |
| FGF13 | fibroblast growth factor 13 | 0.00560152 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00557876 |
| BEX4 | brain expressed, X-linked 4 | 0.00556444 |
| POLR2J | polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa | 0.00555678 |
| PDGFC | platelet derived growth factor C | 0.0055396 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00553721 |
| LY96 | lymphocyte antigen 96 | 0.00552551 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00552345 |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa | 0.00549834 |
| ITM2C | integral membrane protein 2C | 0.00547002 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00545997 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00545298 |
| SLC25A46 | solute carrier family 25, member 46 | 0.0054477 |
| CCN2 | cellular communication network factor 2 | 0.00544586 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00543687 |
| ARG2 | arginase 2 | 0.00542965 |
| TRIB2 | tribbles pseudokinase 2 | 0.00540854 |
| MIR22HG | MIR22 host gene | 0.0054059 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00540398 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00539961 |
| RIN2 | Ras and Rab interactor 2 | 0.00539734 |
| UFM1 | ubiquitin-fold modifier 1 | 0.00537457 |
| PFDN5 | prefoldin subunit 5 | 0.00537169 |
| MARCH2 | membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase | 0.00535843 |
| NLGN4X | neuroligin 4, X-linked | 0.00535559 |
| SIX1 | SIX homeobox 1 | 0.00535007 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00534543 |
| IL7R | interleukin 7 receptor | 0.00532659 |
| BUD31 | BUD31 homolog (S. cerevisiae) | 0.0053259 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00532363 |
| HAT1 | histone acetyltransferase 1 | 0.00531966 |
| BBIP1 | BBSome interacting protein 1 | 0.00531314 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00531007 |
| LRRC15 | leucine rich repeat containing 15 | 0.00530567 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00527596 |
| RGCC | regulator of cell cycle | 0.00527185 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 0.00527061 |
| ANXA5 | annexin A5 | 0.00526409 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.00525802 |
| ANXA2 | annexin A2 | 0.00525556 |
| NUTF2 | nuclear transport factor 2 | 0.00525359 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00525206 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.00524039 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00522631 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00522475 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.00522146 |
| ORC1 | origin recognition complex, subunit 1 | 0.00522141 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00521848 |
| ENSA | endosulfine alpha | 0.00521222 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00519844 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.00519341 |
| MFAP5 | microfibrillar associated protein 5 | 0.00518618 |
| LST1 | leukocyte specific transcript 1 | 0.00517751 |
| PTK2 | protein tyrosine kinase 2 | 0.00516774 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00515922 |
| NRN1 | neuritin 1 | 0.00515104 |
| CFH | complement factor H | 0.00515027 |
| IFI44 | interferon-induced protein 44 | 0.00514639 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00514422 |
| CLIC5 | chloride intracellular channel 5 | 0.00514183 |
| HINT1 | histidine triad nucleotide binding protein 1 | 0.00513512 |
| BTG3 | BTG family, member 3 | 0.00513058 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00513017 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.00512868 |
| TNS1 | tensin 1 | 0.00511064 |
| LOXL2 | lysyl oxidase-like 2 | 0.00509418 |
| MME | membrane metallo-endopeptidase | 0.00508492 |
| LBH | limb bud and heart development | 0.00508242 |
| IRF8 | interferon regulatory factor 8 | 0.00507539 |
| ELN | elastin | 0.00506412 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | 0.00506404 |
| HOXA5 | homeobox A5 | 0.00506146 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00505115 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | 0.00504001 |
| PFDN4 | prefoldin subunit 4 | 0.00503702 |
| LUM | lumican | 0.005032 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00500134 |
| PLAU | plasminogen activator, urokinase | 0.00499532 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0267047 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0196022 |
| CA12 | carbonic anhydrase XII | -0.0154703 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0140686 |
| LCN2 | lipocalin 2 | -0.0135439 |
| S100A9 | S100 calcium binding protein A9 | -0.0127159 |
| MAP7 | microtubule-associated protein 7 | -0.0125112 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0119089 |
| ELANE | elastase, neutrophil expressed | -0.0111165 |
| S100A12 | S100 calcium binding protein A12 | -0.0106593 |
| S100A8 | S100 calcium binding protein A8 | -0.0102665 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00976568 |
| KRT1 | keratin 1, type II | -0.00959462 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.0090064 |
| RHOB | ras homolog family member B | -0.009005 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00894844 |
| CHPT1 | choline phosphotransferase 1 | -0.00884174 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00875105 |
| NDRG1 | N-myc downstream regulated 1 | -0.00865727 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00852287 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00851324 |
| COL1A2 | collagen, type I, alpha 2 | -0.00844688 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00841007 |
| TPD52L1 | tumor protein D52-like 1 | -0.0083268 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00832658 |
| ITM2A | integral membrane protein 2A | -0.00826672 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00822225 |
| TUBA4A | tubulin, alpha 4a | -0.00821402 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00819225 |
| NRCAM | neuronal cell adhesion molecule | -0.00818975 |
| CTSG | cathepsin G | -0.00813511 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00811773 |
| KLK10 | kallikrein-related peptidase 10 | -0.00811063 |
| MMP12 | matrix metallopeptidase 12 | -0.00808725 |
| VNN1 | vanin 1 | -0.00799776 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00799168 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00797271 |
| PPL | periplakin | -0.0078905 |
| PITX3 | paired-like homeodomain 3 | -0.00782653 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00778061 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00776881 |
| PCP4 | Purkinje cell protein 4 | -0.00776873 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | -0.00776194 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00770471 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00768658 |
| CDA | cytidine deaminase | -0.00763649 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00750226 |
| SPRR2B | small proline-rich protein 2B | -0.00749512 |
| NPR3 | natriuretic peptide receptor 3 | -0.00748731 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.00745746 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00742813 |
| MID1IP1 | MID1 interacting protein 1 | -0.00741871 |
| CERS6 | ceramide synthase 6 | -0.00733515 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | -0.00732042 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00727753 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00724784 |
| PLBD1 | phospholipase B domain containing 1 | -0.00723152 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00717987 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00710761 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00699315 |
| S100A7 | S100 calcium binding protein A7 | -0.00698568 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00694582 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00694304 |
| DSG1 | desmoglein 1 | -0.00693164 |
| ADM | adrenomedullin | -0.00690296 |
| GATA6 | GATA binding protein 6 | -0.0068851 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00679795 |
| TYRP1 | tyrosinase-related protein 1 | -0.00678984 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.0067892 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00675976 |
| PRTN3 | proteinase 3 | -0.00675349 |
| MSRB1 | methionine sulfoxide reductase B1 | -0.00673891 |
| CHKB | choline kinase beta | -0.00672873 |
| FZD5 | frizzled class receptor 5 | -0.00669884 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00661659 |
| SLC12A8 | solute carrier family 12, member 8 | -0.00660174 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.00659443 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00656929 |
| RXRA | retinoid X receptor, alpha | -0.00653914 |
| GUCY2C | guanylate cyclase 2C | -0.00653672 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.00653161 |
| STXBP2 | syntaxin binding protein 2 | -0.00651227 |
| KRT16 | keratin 16, type I | -0.00650589 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00641305 |
| GPR88 | G protein-coupled receptor 88 | -0.00641159 |
| DMD | dystrophin | -0.00640683 |
| RAPSN | receptor-associated protein of the synapse | -0.00637437 |
| CEP70 | centrosomal protein 70kDa | -0.00633283 |
| BSG | basigin (Ok blood group) | -0.00631766 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00630717 |
| EHBP1 | EH domain binding protein 1 | -0.00627362 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.00625024 |
| PROM1 | prominin 1 | -0.00622468 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.0062203 |
| ARG1 | arginase 1 | -0.00621542 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -0.00621024 |
| H1-0 | H1.0 linker histone | -0.00620672 |
| PER1 | period circadian clock 1 | -0.00620311 |
| AOC1 | amine oxidase, copper containing 1 | -0.00619272 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0061883 |
| LMNB1 | lamin B1 | -0.00617265 |
| TPP1 | tripeptidyl peptidase I | -0.00616553 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00610762 |
| KIF1B | kinesin family member 1B | -0.00609394 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00608291 |
| TOB2 | transducer of ERBB2, 2 | -0.00604012 |
| GALC | galactosylceramidase | -0.0059804 |
| LOR | loricrin | -0.00597542 |
| MLEC | malectin | -0.00595664 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00595654 |
| MYRF | myelin regulatory factor | -0.00595071 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | -0.00591917 |
| ADCY9 | adenylate cyclase 9 | -0.00591136 |
| PAX6 | paired box 6 | -0.00589966 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00589569 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00587694 |
| JUP | junction plakoglobin | -0.00586968 |
| CRCT1 | cysteine-rich C-terminal 1 | -0.00586665 |
| AZU1 | azurocidin 1 | -0.00584179 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.00583914 |
| EREG | epiregulin | -0.0058168 |
| CALML3 | calmodulin-like 3 | -0.00578691 |
| CD69 | CD69 molecule | -0.0057856 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00578193 |
| STK38 | serine/threonine kinase 38 | -0.00577481 |
| CLIC3 | chloride intracellular channel 3 | -0.00575954 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00575512 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | -0.00575398 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00574062 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00572523 |
| PLSCR4 | phospholipid scramblase 4 | -0.00572202 |
| METRN | meteorin, glial cell differentiation regulator | -0.00571438 |
| FERMT1 | fermitin family member 1 | -0.00571412 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.0057112 |
| VIL1 | villin 1 | -0.00570012 |
| PTCH1 | patched 1 | -0.00567937 |
| TRH | thyrotropin-releasing hormone | -0.0056727 |
| NPTX1 | neuronal pentraxin I | -0.00566674 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00566131 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00565809 |
| SATB2 | SATB homeobox 2 | -0.00565256 |
| PVR | poliovirus receptor | -0.00562226 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00558827 |
| ERAL1 | Era-like 12S mitochondrial rRNA chaperone 1 | -0.00556785 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00556334 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.00554559 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00552626 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00551785 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.0055008 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.00548521 |
| BMP4 | bone morphogenetic protein 4 | -0.00547807 |
| CCKBR | cholecystokinin B receptor | -0.00547403 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00546623 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | -0.00546213 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00545872 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.00542486 |
| POF1B | premature ovarian failure, 1B | -0.00541938 |
| MAGEA3 | melanoma antigen family A3 | -0.0053968 |
| PYGB | phosphorylase, glycogen; brain | -0.00539475 |
| UNC13B | unc-13 homolog B (C. elegans) | -0.00538207 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.00536368 |
| HIRA | histone cell cycle regulator | -0.00535927 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00535865 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.00535584 |
| MEN1 | multiple endocrine neoplasia I | -0.00535545 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | -0.00535373 |
| KLK8 | kallikrein-related peptidase 8 | -0.00534269 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00533777 |
| KLK11 | kallikrein-related peptidase 11 | -0.00532949 |
| FAM102A | family with sequence similarity 102, member A | -0.00532257 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.00532009 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00530261 |
| IL33R | interleukin 33 receptor | -0.0052918 |
| EGR1 | early growth response 1 | -0.0052789 |
| ZNF91 | zinc finger protein 91 | -0.00527708 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00527099 |
| NSG1 | neuron specific gene family member 1 | -0.00527016 |
| USP48 | ubiquitin specific peptidase 48 | -0.00526519 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | -0.00525415 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha | -0.00524959 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00523998 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00522816 |
| HDC | histidine decarboxylase | -0.00522638 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00521037 |
| PITX1 | paired-like homeodomain 1 | -0.00520091 |
| CALB1 | calbindin 1, 28kDa | -0.00519542 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00516623 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.00516057 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00515107 |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | -0.00514192 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | -0.00514034 |
| PPT1 | palmitoyl-protein thioesterase 1 | -0.00513853 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00512571 |
| FLNA | filamin A, alpha | -0.00512214 |
| PKP1 | plakophilin 1 | -0.00511436 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.00511353 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.00510728 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.00510099 |
| S100P | S100 calcium binding protein P | -0.00507868 |
| GPX2 | glutathione peroxidase 2 | -0.00507704 |
| SVIL | supervillin | -0.00506065 |
| HBD | hemoglobin, delta | -0.00504665 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00504225 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.00504196 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | -0.00503731 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00501703 |
| KHSRP | KH-type splicing regulatory protein | -0.00501014 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | -0.00499716 |
| DSP | desmoplakin | -0.00498965 |
| JUNB | jun B proto-oncogene | -0.00497558 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00497416 |
| TLE4 | transducin-like enhancer of split 4 | -0.00496164 |
| PRPH | peripherin | -0.00494976 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00494186 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.00492207 |
| WWC3 | WWC family member 3 | -0.00491557 |
| MRC2 | mannose receptor, C type 2 | -0.0048968 |
| NPY | neuropeptide Y | -0.00489005 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00487847 |
| KLF9 | Kruppel-like factor 9 | -0.00487774 |
| WAC | WW domain containing adaptor with coiled-coil | -0.00487713 |
| DSG3 | desmoglein 3 | -0.00487287 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.00485506 |
| CAPN15 | calpain 15 | -0.00484116 |
| DMXL2 | Dmx-like 2 | -0.00484111 |
| AUTS2 | autism susceptibility candidate 2 | -0.00484059 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00483502 |
| RAB25 | RAB25, member RAS oncogene family | -0.00483369 |
| AFF1 | AF4/FMR2 family, member 1 | -0.00482406 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | -0.00482289 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.00481689 |
| SSBP3 | single stranded DNA binding protein 3 | -0.00481089 |
| COLEC12 | collectin sub-family member 12 | -0.00479826 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.00477785 |
| NISCH | nischarin | -0.00477511 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00477388 |
| ACO2 | aconitase 2, mitochondrial | -0.00476729 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00475667 |
| PGLYRP1 | peptidoglycan recognition protein 1 | -0.00475378 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.00471897 |
| CAMP | cathelicidin antimicrobial peptide | -0.0047176 |
| LY75 | lymphocyte antigen 75 | -0.00471584 |
| KLK6 | kallikrein-related peptidase 6 | -0.00471123 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.004699 |
| MYO6 | myosin VI | -0.00469292 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00468313 |
| HAS2 | hyaluronan synthase 2 | -0.00468006 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00467911 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -0.00466996 |
