CD28 co-stimulation Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-389356
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Genes

33 proteins participating in the CD28 co-stimulation pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
CD28 CD28 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CDC42 cell division cycle 42
FYN FYN proto-oncogene, Src family tyrosine kinase
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PRR5 proline rich 5 (renal)
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RICTOR RPTOR independent companion of MTOR, complex 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
THEM4 thioesterase superfamily member 4
TRIB3 tribbles pseudokinase 3
VAV1 vav 1 guanine nucleotide exchange factor
YES1 YES proto-oncogene 1, Src family tyrosine kinase