CD28 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description CD28 molecule|The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011] (NCBI Entrez Gene Database, 940)
External Link https://ncbi.nlm.nih.gov/gene/940
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Genes

496 genes differentially expressed following the CD28 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAGEA3 melanoma antigen family A3 0.0141463
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.0125684
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0110319
RNF167 ring finger protein 167 0.0106476
GNAS GNAS complex locus 0.0106284
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.0105423
CCL20 chemokine (C-C motif) ligand 20 0.0104517
LGALS13 lectin, galactoside-binding, soluble, 13 0.0104048
XPO7 exportin 7 0.010313
C10ORF10 chromosome 10 open reading frame 10 0.00982155
PRKCA protein kinase C, alpha 0.00946284
DEFB1 defensin, beta 1 0.00932917
MAGEA12 melanoma antigen family A12 0.00922996
KDM5D lysine (K)-specific demethylase 5D 0.00871498
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00862109
USP18 ubiquitin specific peptidase 18 0.00853863
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.00849657
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.0084454
ODAM odontogenic, ameloblast asssociated 0.00829668
PLS3 plastin 3 0.00823005
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00820465
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00815162
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.00814724
MAL mal, T-cell differentiation protein 0.00811561
PRAME preferentially expressed antigen in melanoma 0.00804276
PLAUR plasminogen activator, urokinase receptor 0.00802799
TJP2 tight junction protein 2 0.00799266
ENO2 enolase 2 (gamma, neuronal) 0.0079572
IVNS1ABP influenza virus NS1A binding protein 0.00790516
TUBB2A tubulin, beta 2A class IIa 0.00787679
EDN1 endothelin 1 0.00772996
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00759902
OXTR oxytocin receptor 0.00749402
KRT17 keratin 17, type I 0.00747826
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00742486
TRIM16 tripartite motif containing 16 0.00734411
ZIC1 Zic family member 1 0.00731506
LAMP3 lysosomal-associated membrane protein 3 0.00729196
DIPK1A divergent protein kinase domain 1A 0.00720407
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.0071927
RCAN1 regulator of calcineurin 1 0.00717669
ADM adrenomedullin 0.00716486
ACKR3 atypical chemokine receptor 3 0.00715974
TGM2 transglutaminase 2 0.0071178
ATF3 activating transcription factor 3 0.0070889
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00707468
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00707024
CARMIL1 capping protein regulator and myosin 1 linker 1 0.00706133
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.00705595
CXCL5 chemokine (C-X-C motif) ligand 5 0.00699245
LAMB3 laminin, beta 3 0.00695454
S100A2 S100 calcium binding protein A2 0.00690178
GRAMD2B GRAM domain containing 2B 0.00688553
AUTS2 autism susceptibility candidate 2 0.00686722
ACP6 acid phosphatase 6, lysophosphatidic 0.00684234
OPTN optineurin 0.00683887
MMP12 matrix metallopeptidase 12 0.00681616
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00679851
ACAT2 acetyl-CoA acetyltransferase 2 0.00669645
PFKP phosphofructokinase, platelet 0.00669255
LAPTM4B lysosomal protein transmembrane 4 beta 0.00665964
KIAA0125 KIAA0125 0.00663027
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.0066102
BHLHE41 basic helix-loop-helix family, member e41 0.0065605
JPT2 Jupiter microtubule associated homolog 2 0.00654361
AGTPBP1 ATP/GTP binding protein 1 0.00651091
PITRM1 pitrilysin metallopeptidase 1 0.00651057
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.0064777
SFTPB surfactant protein B 0.00646704
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00645174
EXOC5 exocyst complex component 5 0.00643033
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.0064233
LTBP2 latent transforming growth factor beta binding protein 2 0.00641572
PLCB4 phospholipase C, beta 4 0.00636891
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00635122
SFTPA2 surfactant protein A2 0.00632492
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.00630475
MAGEA1 melanoma antigen family A1 0.00628354
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00627454
IL2RG interleukin 2 receptor, gamma 0.00620459
TPX2 TPX2, microtubule-associated 0.00619659
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.00618418
TLK2 tousled-like kinase 2 0.00617738
FOXG1 forkhead box G1 0.00615565
PDZD2 PDZ domain containing 2 0.00611582
FOSL2 FOS-like antigen 2 0.00610103
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.00609379
PRKCH protein kinase C, eta 0.00607814
LBH limb bud and heart development 0.00606297
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00601981
PSME4 proteasome (prosome, macropain) activator subunit 4 0.00594204
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00592141
LAMC2 laminin, gamma 2 0.00587963
BAMBI BMP and activin membrane-bound inhibitor 0.00582897
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00581704
CXCL8 chemokine (C-X-C motif) ligand 8 0.0058063
TRIM29 tripartite motif containing 29 0.00579882
MAGEA4 melanoma antigen family A4 0.0057983
FXYD5 FXYD domain containing ion transport regulator 5 0.00578206
GDI2 GDP dissociation inhibitor 2 0.00577724
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 0.00575463
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.00574972
MYO5A myosin VA (heavy chain 12, myoxin) 0.00574177
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.00572972
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.00572773
CAPNS1 calpain, small subunit 1 0.0057207
MAB21L1 mab-21-like 1 (C. elegans) 0.00569756
SSR1 signal sequence receptor, alpha 0.005689
SMYD2 SET and MYND domain containing 2 0.00568702
PLAG1 pleiomorphic adenoma gene 1 0.00568695
KRT16 keratin 16, type I 0.00567969
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.00567468
PALLD palladin, cytoskeletal associated protein 0.00565945
GPR183 G protein-coupled receptor 183 0.00565675
MMP10 matrix metallopeptidase 10 0.00565527
MED1 mediator complex subunit 1 0.00564915
PAAF1 proteasomal ATPase-associated factor 1 0.00562278
EYA2 EYA transcriptional coactivator and phosphatase 2 0.00561829
PRPF8 pre-mRNA processing factor 8 0.00561514
MACF1 microtubule-actin crosslinking factor 1 0.00560516
ARFIP2 ADP-ribosylation factor interacting protein 2 0.00558062
TADA2A transcriptional adaptor 2A 0.00555394
ENO1 enolase 1, (alpha) 0.00554555
MUC16 mucin 16, cell surface associated 0.00552527
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00551964
RAB6A RAB6A, member RAS oncogene family 0.00550687
RHOA ras homolog family member A 0.0055042
AARS1 alanyl-tRNA synthetase 1 0.00548229
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.00547891
SORT1 sortilin 1 0.00545658
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00543847
PTHLH parathyroid hormone-like hormone 0.00542456
POGK pogo transposable element with KRAB domain 0.0054182
TP63 tumor protein p63 0.00541649
S100A7 S100 calcium binding protein A7 0.00541355
KLF9 Kruppel-like factor 9 0.00540513
NRN1 neuritin 1 0.00539556
CASC3 cancer susceptibility candidate 3 0.00537059
HSPG2 heparan sulfate proteoglycan 2 0.00535751
KIFAP3 kinesin-associated protein 3 0.00535723
NCF2 neutrophil cytosolic factor 2 0.0053551
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.00535271
YLPM1 YLP motif containing 1 0.00532739
VWA8 von Willebrand factor A domain containing 8 0.00531983
PRUNE1 prune exopolyphosphatase 1 0.00531315
AKR1C2 aldo-keto reductase family 1, member C2 0.00530568
C8ORF4 chromosome 8 open reading frame 4 0.00528266
ELAVL1 ELAV like RNA binding protein 1 0.005273
SCAMP1 secretory carrier membrane protein 1 0.00526023
EPN2 epsin 2 0.00524057
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00523261
ATF6 activating transcription factor 6 0.005202
BCAS3 breast carcinoma amplified sequence 3 0.00518435
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0051773
NCAPD2 non-SMC condensin I complex, subunit D2 0.00517436
RFTN1 raftlin, lipid raft linker 1 0.00517331
IL27RA interleukin 27 receptor, alpha 0.00516648
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00516324
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.0051422
ZNF318 zinc finger protein 318 0.0051322
PRMT1 protein arginine methyltransferase 1 0.00510078
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.00509391
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.00508416
CD70 CD70 molecule 0.0050666
TRIP6 thyroid hormone receptor interactor 6 0.00506585
TMEM255A transmembrane protein 255A 0.00506047
F8 coagulation factor VIII, procoagulant component 0.00505288
DUSP22 dual specificity phosphatase 22 0.00504301
RFC2 replication factor C (activator 1) 2, 40kDa 0.00503726
CD3D CD3d molecule, delta (CD3-TCR complex) 0.00503693
SLAMF7 SLAM family member 7 0.00503479
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00503127
KRT6A keratin 6A, type II 0.00498098
CORO1A coronin, actin binding protein, 1A 0.00497526
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00496616
IL32 interleukin 32 0.00496537
COL7A1 collagen, type VII, alpha 1 0.004965
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0049642
C9ORF3 chromosome 9 open reading frame 3 0.00495699
CXCL13 chemokine (C-X-C motif) ligand 13 0.00495558
SPRR1B small proline-rich protein 1B 0.00495009
BPIFA1 BPI fold containing family A, member 1 0.00494685
CTSZ cathepsin Z 0.00493087
OTULINL OTU deubiquitinase with linear linkage specificity like 0.00492889
RPS5 ribosomal protein S5 0.00491726
OGA O-GlcNAcase 0.00490774
KDM5B lysine (K)-specific demethylase 5B 0.00490574
LRRN3 leucine rich repeat neuronal 3 0.00490481
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00490257
SH3BP4 SH3-domain binding protein 4 0.00490046
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00489956
PTGES prostaglandin E synthase 0.00488247
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 0.00487254
IDE insulin-degrading enzyme 0.00485412
SSX1 synovial sarcoma, X breakpoint 1 0.00483323
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.00483002
MAGEC2 melanoma antigen family C2 0.00482127
NUP205 nucleoporin 205kDa 0.00482127
TKTL1 transketolase-like 1 0.00482083
PER1 period circadian clock 1 0.0048139
ACTA2 actin, alpha 2, smooth muscle, aorta 0.0048095
SCD5 stearoyl-CoA desaturase 5 0.0048025
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 0.00479204
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.00478682
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 0.00478331
PCBP4 poly(rC) binding protein 4 0.00478234
TRAF1 TNF receptor-associated factor 1 0.00477536
LIF leukemia inhibitory factor 0.0047751
NNT nicotinamide nucleotide transhydrogenase 0.00477317
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) 0.00476361
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00476198
GOLGA3 golgin A3 0.00475108
IL13RA2 interleukin 13 receptor, alpha 2 0.00474415
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00473819
WWC2 WW and C2 domain containing 2 0.00473658
KDM3A lysine (K)-specific demethylase 3A 0.00472311
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.00472298
TESC tescalcin 0.00471886
CAPN7 calpain 7 0.00471884
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.0047176
ATP9A ATPase, class II, type 9A 0.00471595
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00471562
SVIL supervillin 0.00469745
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.00469331
OPHN1 oligophrenin 1 0.00468486
ATP10A ATPase, class V, type 10A 0.00466444
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00465152
CALB1 calbindin 1, 28kDa 0.0046504
FAIM Fas apoptotic inhibitory molecule 0.00464904
CAV2 caveolin 2 0.00464895
IGBP1 immunoglobulin (CD79A) binding protein 1 0.00464394
NFYA nuclear transcription factor Y, alpha 0.00464309
MED6 mediator complex subunit 6 0.00463102
ZMIZ2 zinc finger, MIZ-type containing 2 0.00461481
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00461013
WDR7 WD repeat domain 7 0.00460981
ZNF410 zinc finger protein 410 0.00460628
RGS1 regulator of G-protein signaling 1 0.00460614
TDP1 tyrosyl-DNA phosphodiesterase 1 0.00460032
LYST lysosomal trafficking regulator 0.00459373
IL2RB interleukin 2 receptor, beta 0.00458415
SRP72 signal recognition particle 72kDa 0.00458101
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.00457493
CDA cytidine deaminase 0.0045745
CD2 CD2 molecule 0.00457257
YARS1 tyrosyl-tRNA synthetase 1 0.00456983
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 0.00455758
BCL2A1 BCL2-related protein A1 0.00455436

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0183708
MAP7 microtubule-associated protein 7 -0.0165624
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0156986
METRN meteorin, glial cell differentiation regulator -0.0155414
APOD apolipoprotein D -0.0141246
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0133491
SCGB1D2 secretoglobin, family 1D, member 2 -0.0131435
ADIRF adipogenesis regulatory factor -0.0131406
TNNT1 troponin T type 1 (skeletal, slow) -0.0124697
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0123306
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.012226
CLU clusterin -0.0114859
TSPAN13 tetraspanin 13 -0.0114842
SCGB2A1 secretoglobin, family 2A, member 1 -0.0114594
SPARCL1 SPARC-like 1 (hevin) -0.0112427
COL11A1 collagen, type XI, alpha 1 -0.0110485
CDC20 cell division cycle 20 -0.0107195
GAS1 growth arrest-specific 1 -0.0106943
ESR1 estrogen receptor 1 -0.010682
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0104165
MT1E metallothionein 1E -0.0102244
XIC X chromosome inactivation center -0.0102175
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0102088
NPY neuropeptide Y -0.0101911
PRSS3 protease, serine, 3 -0.0101579
PRR15L proline rich 15-like -0.00998309
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00995262
HEPH hephaestin -0.00993423
FRZB frizzled-related protein -0.00988553
NRGN neurogranin (protein kinase C substrate, RC3) -0.00987629
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00977511
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00968774
CCNG2 cyclin G2 -0.00954445
BEX1 brain expressed, X-linked 1 -0.00954171
SKAP2 src kinase associated phosphoprotein 2 -0.00947872
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00933112
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -0.00932647
NPY1R neuropeptide Y receptor Y1 -0.00923915
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00915176
ANPEP alanyl (membrane) aminopeptidase -0.00906851
CPB1 carboxypeptidase B1 (tissue) -0.00899522
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00883209
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00881103
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00873963
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00869416
FGFR3 fibroblast growth factor receptor 3 -0.00867258
ABHD3 abhydrolase domain containing 3 -0.00866839
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00866576
SLC38A1 solute carrier family 38, member 1 -0.00860043
PDZK1 PDZ domain containing 1 -0.00859638
ISYNA1 inositol-3-phosphate synthase 1 -0.00858458
MT1F metallothionein 1F -0.00858415
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00857633
FGF13 fibroblast growth factor 13 -0.00855102
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00848306
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00847979
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) -0.00846708
TPSAB1 tryptase alpha/beta 1 -0.00844337
THY1 Thy-1 cell surface antigen -0.00843089
IL1R1 interleukin 1 receptor, type I -0.00827382
STXBP2 syntaxin binding protein 2 -0.00826288
MEN1 multiple endocrine neoplasia I -0.00825888
ECM1 extracellular matrix protein 1 -0.00824405
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.00824274
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00815751
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00814026
MT1M metallothionein 1M -0.00802282
ZNF91 zinc finger protein 91 -0.00800343
METTL7A methyltransferase like 7A -0.00797016
OLFML3 olfactomedin-like 3 -0.00789691
RAPSN receptor-associated protein of the synapse -0.00779974
NPTX2 neuronal pentraxin II -0.00777264
CCND2 cyclin D2 -0.00775624
NMU neuromedin U -0.00773968
CA2 carbonic anhydrase II -0.00754372
FKBP4 FK506 binding protein 4, 59kDa -0.00751643
COL10A1 collagen, type X, alpha 1 -0.00749655
CCK cholecystokinin -0.00740302
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00740194
RGS13 regulator of G-protein signaling 13 -0.00739517
CRIP2 cysteine-rich protein 2 -0.00734015
CD36 CD36 molecule (thrombospondin receptor) -0.0073114
ADGRG2 adhesion G protein-coupled receptor G2 -0.00726823
HOPX HOP homeobox -0.0072682
TPD52L1 tumor protein D52-like 1 -0.00725892
ZFP36L1 ZFP36 ring finger protein-like 1 -0.00725454
GLB1L2 galactosidase, beta 1-like 2 -0.00725203
MT1H metallothionein 1H -0.00725128
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00723686
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00721757
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A -0.0072097
TOB1 transducer of ERBB2, 1 -0.00720296
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00717299
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00716017
CHRDL1 chordin-like 1 -0.0071048
CRISP3 cysteine-rich secretory protein 3 -0.00700716
PDGFD platelet derived growth factor D -0.00698296
DPYSL2 dihydropyrimidinase-like 2 -0.00695821
PCP4 Purkinje cell protein 4 -0.00693264
PAX5 paired box 5 -0.00692448
DEPTOR DEP domain containing MTOR-interacting protein -0.00692425
LEF1 lymphoid enhancer-binding factor 1 -0.00691216
BMP4 bone morphogenetic protein 4 -0.00688227
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00687438
KRT8 keratin 8, type II -0.00686864
ARHGAP29 Rho GTPase activating protein 29 -0.00685607
SGK1 serum/glucocorticoid regulated kinase 1 -0.00684235
VPREB3 pre-B lymphocyte 3 -0.00679731
COL5A2 collagen, type V, alpha 2 -0.0067891
MB myoglobin -0.00675003
CRIP1 cysteine-rich protein 1 (intestinal) -0.00674848
PFKM phosphofructokinase, muscle -0.00672518
SCGB2A2 secretoglobin, family 2A, member 2 -0.00672288
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00671471
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00671358
CST6 cystatin E/M -0.00670467
ANKRD10 ankyrin repeat domain 10 -0.00669302
SPON2 spondin 2, extracellular matrix protein -0.0066838
NT5E 5'-nucleotidase, ecto (CD73) -0.00666253
PKP2 plakophilin 2 -0.00664994
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -0.00662297
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.0066035
SECTM1 secreted and transmembrane 1 -0.00660246
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00659055
TMSB15A thymosin beta 15a -0.00658929
TFF3 trefoil factor 3 (intestinal) -0.00656734
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.00656176
VCAM1 vascular cell adhesion molecule 1 -0.00655148
MT1G metallothionein 1G -0.00653152
AKAP7 A kinase (PRKA) anchor protein 7 -0.00652676
ABAT 4-aminobutyrate aminotransferase -0.0065127
CPE carboxypeptidase E -0.00650591
HBB hemoglobin, beta -0.00650022
TST thiosulfate sulfurtransferase (rhodanese) -0.00648344
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00647378
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00646866
SST somatostatin -0.00645739
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00645298
ANXA4 annexin A4 -0.0064341
SYBU syntabulin (syntaxin-interacting) -0.00641637
FBXO2 F-box protein 2 -0.00639962
EIF5A eukaryotic translation initiation factor 5A -0.00639497
GJA1 gap junction protein, alpha 1, 43kDa -0.00632881
LXN latexin -0.00631515
PXDN peroxidasin -0.00627624
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -0.00621934
COMP cartilage oligomeric matrix protein -0.00620688
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00620242
PROM1 prominin 1 -0.00620221
HSPA2 heat shock 70kDa protein 2 -0.00620204
IL17RB interleukin 17 receptor B -0.00618522
FBXL14 F-box and leucine-rich repeat protein 14 -0.0061542
RGS4 regulator of G-protein signaling 4 -0.00614535
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00611154
PPL periplakin -0.00606563
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00605855
MT1HL1 metallothionein 1H-like 1 -0.00605741
CLC Charcot-Leyden crystal galectin -0.00603939
SIKE1 suppressor of IKBKE 1 -0.00603491
SCAND1 SCAN domain containing 1 -0.00602078
SLC44A4 solute carrier family 44, member 4 -0.00601394
PID1 phosphotyrosine interaction domain containing 1 -0.00601346
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00601189
RET ret proto-oncogene -0.00601181
SLBP stem-loop binding protein -0.00600705
KIF1A kinesin family member 1A -0.00599724
DUSP6 dual specificity phosphatase 6 -0.00598253
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.0059783
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00597701
CTSH cathepsin H -0.00597037
NDN necdin, melanoma antigen (MAGE) family member -0.00594188
TTYH1 tweety family member 1 -0.00593536
S100P S100 calcium binding protein P -0.0059235
BLNK B-cell linker -0.00591821
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00591606
C14ORF132 chromosome 14 open reading frame 132 -0.00587929
PDLIM5 PDZ and LIM domain 5 -0.00585827
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00584679
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00583667
KAZN kazrin, periplakin interacting protein -0.0058304
NOTCH2NL notch 2 N-terminal like -0.00582876
GPM6B glycoprotein M6B -0.00582465
ADD3 adducin 3 (gamma) -0.00579711
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0057788
PPP1R16B protein phosphatase 1, regulatory subunit 16B -0.00577303
RTN2 reticulon 2 -0.00577267
HAUS3 HAUS augmin-like complex, subunit 3 -0.00576395
EREG epiregulin -0.00576243
CD52 CD52 molecule -0.00575019
SPON1 spondin 1, extracellular matrix protein -0.00574143
SCRG1 stimulator of chondrogenesis 1 -0.00569909
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00569538
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00568329
SMC1A structural maintenance of chromosomes 1A -0.00566712
PUDP pseudouridine 5'-phosphatase -0.00566285
BEX4 brain expressed, X-linked 4 -0.0056516
PLSCR4 phospholipid scramblase 4 -0.00565001
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.00563504
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.00563155
DENND2D DENN/MADD domain containing 2D -0.00562881
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00562784
ARMT1 acidic residue methyltransferase 1 -0.00562098
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00562012
EDN3 endothelin 3 -0.00561553
STK39 serine threonine kinase 39 -0.00558084
RGS16 regulator of G-protein signaling 16 -0.00556552
SNAI2 snail family zinc finger 2 -0.00555108
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00554375
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.0055381
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00553124
WT1 Wilms tumor 1 -0.00550474
EZR ezrin -0.00550159
PRSS8 protease, serine, 8 -0.00550134
SC5D sterol-C5-desaturase -0.00549866
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00548316
DMBT1 deleted in malignant brain tumors 1 -0.00545868
PTGDS prostaglandin D2 synthase 21kDa (brain) -0.00545434
RBBP8 retinoblastoma binding protein 8 -0.00544782
CD320 CD320 molecule -0.00543092
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -0.00542447
ZCCHC10 zinc finger, CCHC domain containing 10 -0.00542038
MCFD2 multiple coagulation factor deficiency 2 -0.00541982
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.00541573
FZD2 frizzled class receptor 2 -0.00541123
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00540947
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00539129
PTK2B protein tyrosine kinase 2 beta -0.00539102
PARM1 prostate androgen-regulated mucin-like protein 1 -0.00538879
RHOBTB3 Rho-related BTB domain containing 3 -0.00538432
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -0.00536687
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -0.00534861
DNALI1 dynein, axonemal, light intermediate chain 1 -0.00534318
OAT ornithine aminotransferase -0.00533734
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.00532772
PEG3 paternally expressed 3 -0.00532222
TOR1A torsin family 1, member A (torsin A) -0.00530976
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.0053039
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00530241
AHR aryl hydrocarbon receptor -0.00527996
TGIF1 TGFB-induced factor homeobox 1 -0.00527676
NNMT nicotinamide N-methyltransferase -0.00525366
WBP5 WW domain binding protein 5 -0.00525213
PLCH1 phospholipase C, eta 1 -0.00525112
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00524778
MAPK13 mitogen-activated protein kinase 13 -0.0052445
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.00522391
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -0.00521645
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00520666