CD3D Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description CD3d molecule, delta (CD3-TCR complex)|The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009] (NCBI Entrez Gene Database, 915)
External Link https://ncbi.nlm.nih.gov/gene/915
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Genes

497 genes differentially expressed following the CD3D gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
XPO7 exportin 7 0.0209935
NVL nuclear VCP-like 0.0167566
CNPY3 canopy FGF signaling regulator 3 0.013471
PLK1 polo-like kinase 1 0.0120515
GAB2 GRB2-associated binding protein 2 0.0115971
CXCL14 chemokine (C-X-C motif) ligand 14 0.0110429
RNF167 ring finger protein 167 0.00973148
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.00972677
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00966693
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00954324
ERBB3 erb-b2 receptor tyrosine kinase 3 0.0093763
NKX2-1 NK2 homeobox 1 0.00930938
BPHL biphenyl hydrolase-like (serine hydrolase) 0.0092471
CDCA4 cell division cycle associated 4 0.00902037
THBS2 thrombospondin 2 0.00894847
RETREG1 reticulophagy regulator 1 0.00877519
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 0.00866826
FAM13A family with sequence similarity 13, member A 0.00857285
C9ORF3 chromosome 9 open reading frame 3 0.00848609
PCBP1 poly(rC) binding protein 1 0.00842173
EPCAM epithelial cell adhesion molecule 0.00827183
SHTN1 shootin 1 0.00812583
PIEZO2 piezo-type mechanosensitive ion channel component 2 0.00812159
FBP1 fructose-1,6-bisphosphatase 1 0.00811443
LDOC1 leucine zipper, down-regulated in cancer 1 0.00799014
L1CAM L1 cell adhesion molecule 0.00795848
RNPS1 RNA binding protein S1, serine-rich domain 0.00793804
FZD5 frizzled class receptor 5 0.00790151
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 0.00788097
GNAS GNAS complex locus 0.00781159
BST2 bone marrow stromal cell antigen 2 0.00770503
WDR26 WD repeat domain 26 0.00767766
CALCA calcitonin-related polypeptide alpha 0.00766954
CSK c-src tyrosine kinase 0.00766641
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.00761402
CTSC cathepsin C 0.00756738
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.00748088
UNC13B unc-13 homolog B (C. elegans) 0.00744735
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00738917
AURKB aurora kinase B 0.0073662
CTSV cathepsin V 0.00729238
SFTPB surfactant protein B 0.00726354
CDCA3 cell division cycle associated 3 0.00726138
TUBB2B tubulin, beta 2B class IIb 0.00720689
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.00717673
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.0071553
SMC1A structural maintenance of chromosomes 1A 0.00713994
HOMER2 homer scaffolding protein 2 0.00712735
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 0.00712502
PHF10 PHD finger protein 10 0.00710902
DSG1 desmoglein 1 0.00704926
CRLF1 cytokine receptor-like factor 1 0.007047
AHNAK2 AHNAK nucleoprotein 2 0.0070396
DDR2 discoidin domain receptor tyrosine kinase 2 0.00703742
MX1 MX dynamin-like GTPase 1 0.00700817
MYO1D myosin ID 0.00696091
COL9A3 collagen, type IX, alpha 3 0.00695842
PON3 paraoxonase 3 0.00693529
LAMP3 lysosomal-associated membrane protein 3 0.00690599
DIPK1A divergent protein kinase domain 1A 0.00688047
PNN pinin, desmosome associated protein 0.00678992
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.00678517
TCP1 t-complex 1 0.00676123
PBX3 pre-B-cell leukemia homeobox 3 0.00675949
ACKR3 atypical chemokine receptor 3 0.00675495
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.00674893
PMM2 phosphomannomutase 2 0.00673286
EMP2 epithelial membrane protein 2 0.0066892
LMO3 LIM domain only 3 (rhombotin-like 2) 0.006643
CXADR coxsackie virus and adenovirus receptor 0.00663656
LOR loricrin 0.00663126
LAMP5 lysosomal-associated membrane protein family, member 5 0.00661433
CFB complement factor B 0.00656495
ACAT2 acetyl-CoA acetyltransferase 2 0.00654343
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.00653584
HAL histidine ammonia-lyase 0.00651682
IFRD2 interferon-related developmental regulator 2 0.00650293
DSC1 desmocollin 1 0.00649604
IFITM1 interferon induced transmembrane protein 1 0.00645524
CDK18 cyclin-dependent kinase 18 0.00642179
SULF1 sulfatase 1 0.00641474
SFTPA2 surfactant protein A2 0.00637782
NRN1 neuritin 1 0.00636186
SRM spermidine synthase 0.00634409
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.00633577
FUS FUS RNA binding protein 0.00631913
WARS1 tryptophanyl-tRNA synthetase 1 0.00629725
PTBP1 polypyrimidine tract binding protein 1 0.00629658
EXOC5 exocyst complex component 5 0.00627734
MAT2A methionine adenosyltransferase II, alpha 0.00625063
SLIT2 slit homolog 2 (Drosophila) 0.0062227
KLK7 kallikrein-related peptidase 7 0.00619419
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.00619014
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00618389
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 0.00613589
FRS2 fibroblast growth factor receptor substrate 2 0.00613188
TCTA T-cell leukemia translocation altered 0.00612404
PER3 period circadian clock 3 0.00612248
KLF6 Kruppel-like factor 6 0.00610583
DCLK1 doublecortin-like kinase 1 0.00610074
MX2 MX dynamin-like GTPase 2 0.00609658
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.00609008
TMEM45A transmembrane protein 45A 0.00607788
VANGL1 VANGL planar cell polarity protein 1 0.00606604
TBCD tubulin folding cofactor D 0.00604185
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00604028
NELL2 NEL-like 2 (chicken) 0.00603156
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 0.00601706
XPO6 exportin 6 0.00600089
PCCB propionyl CoA carboxylase, beta polypeptide 0.00599705
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00599433
DAPK1 death-associated protein kinase 1 0.00598066
SPTSSA serine palmitoyltransferase, small subunit A 0.00593662
CD4 CD4 molecule 0.00590736
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.0059066
NAV2 neuron navigator 2 0.0059064
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.00589328
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00588692
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00588501
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.00585836
RGS5 regulator of G-protein signaling 5 0.00584973
CBFB core-binding factor, beta subunit 0.00584911
PRPF8 pre-mRNA processing factor 8 0.00584759
MMP3 matrix metallopeptidase 3 0.00584109
FBXO28 F-box protein 28 0.00583502
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.00582763
RNASEH2A ribonuclease H2, subunit A 0.00580851
FAM120A family with sequence similarity 120A 0.00578542
NEK3 NIMA-related kinase 3 0.00577477
CD93 CD93 molecule 0.00576419
GRP gastrin-releasing peptide 0.00576129
TJP2 tight junction protein 2 0.0057572
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.00574422
ALDOA aldolase A, fructose-bisphosphate 0.00573117
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.00572383
AARS1 alanyl-tRNA synthetase 1 0.00572251
CISH cytokine inducible SH2-containing protein 0.00570989
AK2 adenylate kinase 2 0.0056932
COL9A2 collagen, type IX, alpha 2 0.00568464
STMN2 stathmin 2 0.00567736
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.00566869
LEPROTL1 leptin receptor overlapping transcript-like 1 0.00566683
HPD 4-hydroxyphenylpyruvate dioxygenase 0.00563888
SDC2 syndecan 2 0.0056174
PGS1 phosphatidylglycerophosphate synthase 1 0.00561159
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.00561053
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.00560966
PLAT plasminogen activator, tissue 0.00560822
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00558916
ZNF536 zinc finger protein 536 0.00558852
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00557647
ADAMTSL3 ADAMTS-like 3 0.00557559
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 0.00557272
AFF1 AF4/FMR2 family, member 1 0.00556362
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.00555346
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.00555084
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00554836
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 0.00554394
BCLAF1 BCL2-associated transcription factor 1 0.00553504
OGDHL oxoglutarate dehydrogenase-like 0.00552731
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.0055183
GP1BB glycoprotein Ib (platelet), beta polypeptide 0.00551625
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.00551261
ANOS1 anosmin 1 0.00550383
CSNK2B casein kinase 2, beta polypeptide 0.00550218
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.00549984
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.00549475
MYO1B myosin IB 0.00549361
ESRP1 epithelial splicing regulatory protein 1 0.00547281
IL16 interleukin 16 0.00547271
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.00546989
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00545448
CCNI cyclin I 0.00544791
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 0.00543931
GSTT1 glutathione S-transferase theta 1 0.00543631
IFITM3 interferon induced transmembrane protein 3 0.00541832
RET ret proto-oncogene 0.00541374
STC1 stanniocalcin 1 0.00539264
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00539154
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00538661
CIT citron rho-interacting serine/threonine kinase 0.00538562
HPCAL1 hippocalcin-like 1 0.00537637
NPIPA1 nuclear pore complex interacting protein family, member A1 0.0053754
RAB17 RAB17, member RAS oncogene family 0.00537411
CNBP CCHC-type zinc finger, nucleic acid binding protein 0.00537399
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00537224
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.00537031
PBK PDZ binding kinase 0.00535919
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00534202
GLO1 glyoxalase I 0.00534015
IFITM2 interferon induced transmembrane protein 2 0.00533619
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.00532835
OSBPL3 oxysterol binding protein-like 3 0.00532587
GAS2 growth arrest-specific 2 0.00531989
SPP1 secreted phosphoprotein 1 0.00528038
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.00527724
ACTB actin, beta 0.00526485
NUCLEOLIN nucleolin multifunctional protein 0.00525422
UTRN utrophin 0.00525091
TEX261 testis expressed 261 0.00524541
XPC xeroderma pigmentosum, complementation group C 0.00524485
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.0052421
PNPLA3 patatin-like phospholipase domain containing 3 0.00523874
ACTN4 actinin, alpha 4 0.00522347
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00522317
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.00521955
ESRP2 epithelial splicing regulatory protein 2 0.00519624
ASF1B anti-silencing function 1B histone chaperone 0.00518839
DKC1 dyskeratosis congenita 1, dyskerin 0.00518214
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 0.00518085
PCYOX1 prenylcysteine oxidase 1 0.00517794
CYB5R2 cytochrome b5 reductase 2 0.00517517
CENPF centromere protein F, 350/400kDa 0.00517397
SARAF store-operated calcium entry-associated regulatory factor 0.00516068
TNS1 tensin 1 0.00515886
SON SON DNA binding protein 0.0051486
TMEM214 transmembrane protein 214 0.00514515
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00514471
LAPTM4B lysosomal protein transmembrane 4 beta 0.00514215
ZBED1 zinc finger, BED-type containing 1 0.0051264
ODAM odontogenic, ameloblast asssociated 0.00512384
L1TD1 LINE-1 type transposase domain containing 1 0.00512357
HYAL1 hyaluronoglucosaminidase 1 0.0051196
ALDOC aldolase C, fructose-bisphosphate 0.00511216
SERINC5 serine incorporator 5 0.00510947
WDR7 WD repeat domain 7 0.00510938
SNRPA small nuclear ribonucleoprotein polypeptide A 0.00510635
TOP1 topoisomerase (DNA) I 0.00509889
GBP1 guanylate binding protein 1, interferon-inducible 0.0050751
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.00507315
PXDN peroxidasin 0.00507009
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.00506832
TPM4 tropomyosin 4 0.00506697
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.0050648
RBM5 RNA binding motif protein 5 0.00505153
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.00504812
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00504194
AUTS2 autism susceptibility candidate 2 0.00503974
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 0.00503067
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.00502565
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 0.00501691
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 0.00499746
GDI1 GDP dissociation inhibitor 1 0.00499504
MTUS1 microtubule associated tumor suppressor 1 0.00499375
ENO1 enolase 1, (alpha) 0.00497979
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.00497727
ADAR adenosine deaminase, RNA-specific 0.00497659
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00497287
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 0.00497099
STOM stomatin 0.00496791

decreased expression

Symbol Name Standardized Value
LTF lactotransferrin -0.0207238
KRT19 keratin 19, type I -0.0174983
MYBPC1 myosin binding protein C, slow type -0.0159779
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.0144426
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0138995
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.0136371
KRT5 keratin 5, type II -0.0132831
CSTA cystatin A (stefin A) -0.0130242
METRN meteorin, glial cell differentiation regulator -0.0128729
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.0124525
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.0123038
S100P S100 calcium binding protein P -0.0120905
RRAGD Ras-related GTP binding D -0.0120502
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0119092
APOD apolipoprotein D -0.0118584
TTN titin -0.0118146
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0116353
DLK1 delta-like 1 homolog (Drosophila) -0.0116336
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0116046
ANXA1 annexin A1 -0.0114424
CLU clusterin -0.0114253
TNNT1 troponin T type 1 (skeletal, slow) -0.0113236
ACTA1 actin, alpha 1, skeletal muscle -0.0111797
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.0111521
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0110546
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.0109668
KRT13 keratin 13, type I -0.010957
PLK2 polo-like kinase 2 -0.0107348
FXYD3 FXYD domain containing ion transport regulator 3 -0.0106796
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.0105849
MB myoglobin -0.0104287
AKR1C3 aldo-keto reductase family 1, member C3 -0.0103683
LGALS3 lectin, galactoside-binding, soluble, 3 -0.0103372
MT1X metallothionein 1X -0.0103293
CRISP3 cysteine-rich secretory protein 3 -0.0103113
BASP1 brain abundant, membrane attached signal protein 1 -0.0102348
IQCG IQ motif containing G -0.0102342
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.0101519
FTH1 ferritin, heavy polypeptide 1 -0.00995613
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00991243
NAMPT nicotinamide phosphoribosyltransferase -0.00990622
SRPX sushi-repeat containing protein, X-linked -0.00990606
PITX3 paired-like homeodomain 3 -0.00984417
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00975095
SLN sarcolipin -0.00966293
IGFBP4 insulin-like growth factor binding protein 4 -0.00963645
SCGB1D2 secretoglobin, family 1D, member 2 -0.00959767
MMP7 matrix metallopeptidase 7 -0.00955691
S100A9 S100 calcium binding protein A9 -0.00951297
C1S complement component 1, s subcomponent -0.00946994
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00942037
KRT15 keratin 15, type I -0.00942004
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00941305
KLHL41 kelch-like family member 41 -0.00938934
PDLIM5 PDZ and LIM domain 5 -0.00934616
MT1E metallothionein 1E -0.00933952
CKM creatine kinase, muscle -0.00929748
MSMB microseminoprotein, beta- -0.00929517
SCAF4 SR-related CTD-associated factor 4 -0.00925585
CPA3 carboxypeptidase A3 (mast cell) -0.00924808
NRCAM neuronal cell adhesion molecule -0.00924059
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00923329
FABP7 fatty acid binding protein 7, brain -0.00918754
CD59 CD59 molecule, complement regulatory protein -0.00917696
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00915802
DUSP5 dual specificity phosphatase 5 -0.00913274
FEM1C fem-1 homolog c (C. elegans) -0.00900085
CNR1 cannabinoid receptor 1 (brain) -0.00897277
TRIB2 tribbles pseudokinase 2 -0.00892431
HIST1H2BD histone cluster 1, H2bd -0.00890548
CNN3 calponin 3, acidic -0.00887807
RHOBTB3 Rho-related BTB domain containing 3 -0.00885621
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00882935
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00874536
PROM1 prominin 1 -0.00870011
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00868205
GPM6B glycoprotein M6B -0.00867461
SCGB2A2 secretoglobin, family 2A, member 2 -0.00867042
G0S2 G0/G1 switch 2 -0.00864496
ADAM9 ADAM metallopeptidase domain 9 -0.00860879
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.00858624
MXRA7 matrix-remodelling associated 7 -0.0085566
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00849232
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.0084448
MT1M metallothionein 1M -0.00843166
EIF5A eukaryotic translation initiation factor 5A -0.00838781
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00835425
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00830846
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -0.00827581
SCPEP1 serine carboxypeptidase 1 -0.00827198
GOLM1 golgi membrane protein 1 -0.00826943
EFHC2 EF-hand domain (C-terminal) containing 2 -0.00821863
CFD complement factor D (adipsin) -0.00819565
ZNF91 zinc finger protein 91 -0.00814983
FGFR3 fibroblast growth factor receptor 3 -0.00814906
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00811583
MYH2 myosin, heavy chain 2, skeletal muscle, adult -0.00810775
HEPH hephaestin -0.00809949
PEG3 paternally expressed 3 -0.00809813
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.00807271
TPD52L1 tumor protein D52-like 1 -0.00805799
TACSTD2 tumor-associated calcium signal transducer 2 -0.00801669
CD52 CD52 molecule -0.00801549
TRIM29 tripartite motif containing 29 -0.00800541
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00799353
LOXL1 lysyl oxidase-like 1 -0.00796856
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00793048
NME5 NME/NM23 family member 5 -0.00792774
PDE4DIP phosphodiesterase 4D interacting protein -0.00788671
CDC20 cell division cycle 20 -0.00787302
ZEB1 zinc finger E-box binding homeobox 1 -0.00784133
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00780554
AKAP12 A kinase (PRKA) anchor protein 12 -0.00776578
MYOT myotilin -0.00775168
GALC galactosylceramidase -0.00768331
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.00767089
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00762902
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00762182
BLVRB biliverdin reductase B -0.00759778
ALOX5 arachidonate 5-lipoxygenase -0.00759599
FABP4 fatty acid binding protein 4, adipocyte -0.00759326
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00759195
HIST1H2AE histone cluster 1, H2ae -0.00758948
MT1F metallothionein 1F -0.00758822
BTG1 B-cell translocation gene 1, anti-proliferative -0.00758036
FHL1 four and a half LIM domains 1 -0.00750873
ACTN2 actinin, alpha 2 -0.00750521
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00749761
CHI3L2 chitinase 3-like 2 -0.00748943
SPARCL1 SPARC-like 1 (hevin) -0.00745102
TSPAN5 tetraspanin 5 -0.00744573
CRYAB crystallin, alpha B -0.0074398
TBC1D31 TBC1 domain family, member 31 -0.00742849
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00738318
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00734701
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00734507
TSPO translocator protein (18kDa) -0.00731429
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00731118
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00727604
XYLT1 xylosyltransferase I -0.00721739
C1ORF54 chromosome 1 open reading frame 54 -0.00721489
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00721195
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.0071791
LXN latexin -0.007173
PLTP phospholipid transfer protein -0.0071673
EMP3 epithelial membrane protein 3 -0.00715503
SPRY2 sprouty homolog 2 (Drosophila) -0.00715184
CENPU centromere protein U -0.00713972
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00712783
PDLIM4 PDZ and LIM domain 4 -0.00708022
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -0.00707954
TSPAN7 tetraspanin 7 -0.00704965
GAS1 growth arrest-specific 1 -0.00701587
TWF1 twinfilin actin binding protein 1 -0.00699394
SOD2 superoxide dismutase 2, mitochondrial -0.00697986
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00696502
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.0069577
VAV3 vav 3 guanine nucleotide exchange factor -0.00694364
GSAP gamma-secretase activating protein -0.00693605
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00691792
HOPX HOP homeobox -0.00690761
NIBAN1 niban apoptosis regulator 1 -0.00687381
TNNC1 troponin C type 1 (slow) -0.00685958
VCAM1 vascular cell adhesion molecule 1 -0.0068392
HSF2 heat shock transcription factor 2 -0.00682938
NPC2 Niemann-Pick disease, type C2 -0.00682856
TPSAB1 tryptase alpha/beta 1 -0.0068136
AKAP7 A kinase (PRKA) anchor protein 7 -0.00679971
SLC38A1 solute carrier family 38, member 1 -0.00678539
BCL2A1 BCL2-related protein A1 -0.00677378
CCDC176 coiled-coil domain containing 176 -0.00675895
IER5 immediate early response 5 -0.00675768
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00673454
ARL4A ADP-ribosylation factor-like 4A -0.00672884
FSTL1 follistatin-like 1 -0.00672095
MGST3 microsomal glutathione S-transferase 3 -0.00671677
ANXA2P2 annexin A2 pseudogene 2 -0.00671552
GOLGA8A golgin A8 family, member A -0.00667635
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -0.00664907
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -0.00663032
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00661815
TPM3 tropomyosin 3 -0.00659487
RYR3 ryanodine receptor 3 -0.00658306
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00657607
ZBTB18 zinc finger and BTB domain containing 18 -0.00657344
CLGN calmegin -0.00657053
SCN3A sodium channel, voltage gated, type III alpha subunit -0.00656466
CCND2 cyclin D2 -0.00656397
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.0065638
SMPX small muscle protein, X-linked -0.0065522
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00654353
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00653624
GSDME gasdermin E -0.00652808
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -0.00651244
ANKRD36 ankyrin repeat domain 36 -0.00648656
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00645255
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -0.00643427
GSDMB gasdermin B -0.00642518
C1R complement component 1, r subcomponent -0.00641043
PBX1 pre-B-cell leukemia homeobox 1 -0.00640771
CADPS2 Ca++-dependent secretion activator 2 -0.00640671
LDB3 LIM domain binding 3 -0.00638369
PAQR3 progestin and adipoQ receptor family member III -0.00637959
ING2 inhibitor of growth family, member 2 -0.00636788
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -0.00636353
F3 coagulation factor III (thromboplastin, tissue factor) -0.00635978
WBP5 WW domain binding protein 5 -0.00631546
COCH cochlin -0.0063131
SCGB2A1 secretoglobin, family 2A, member 1 -0.00629997
GJA1 gap junction protein, alpha 1, 43kDa -0.00629981
GLUL glutamate-ammonia ligase -0.00629391
PNMA1 paraneoplastic Ma antigen 1 -0.00629371
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00628649
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00628431
CD83 CD83 molecule -0.00628172
ZBTB10 zinc finger and BTB domain containing 10 -0.00627898
PERP PERP, TP53 apoptosis effector -0.00627476
EFNB2 ephrin-B2 -0.00625375
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00624459
CD38 CD38 molecule -0.00624403
TOB1 transducer of ERBB2, 1 -0.00622048
SGK1 serum/glucocorticoid regulated kinase 1 -0.00622036
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00622007
AOC1 amine oxidase, copper containing 1 -0.00621217
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -0.00620869
COX11 COX11 cytochrome c oxidase copper chaperone -0.00619739
ZNF652 zinc finger protein 652 -0.00617417
HSPA2 heat shock 70kDa protein 2 -0.00616482
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00616076
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00615437
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00615282
DES desmin -0.00613214
MYBPC2 myosin binding protein C, fast type -0.00612418
GPRC5B G protein-coupled receptor, class C, group 5, member B -0.00611007
PENK proenkephalin -0.00609413
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -0.00608863
MYOM2 myomesin 2 -0.00608714
TNNC2 troponin C type 2 (fast) -0.00607372
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00607227
IRS2 insulin receptor substrate 2 -0.00606365
CCNG2 cyclin G2 -0.00605716
DSG3 desmoglein 3 -0.00603695
CCDC69 coiled-coil domain containing 69 -0.00602805
PDLIM3 PDZ and LIM domain 3 -0.00600502
COL6A2 collagen, type VI, alpha 2 -0.00599893
STATH statherin -0.00597356
CHRDL1 chordin-like 1 -0.00596648