| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | CD4 molecule|This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010] (NCBI Entrez Gene Database, 920) |
| External Link | https://ncbi.nlm.nih.gov/gene/920 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the CD4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADD3 | adducin 3 (gamma) | 0.0155756 |
| RNF167 | ring finger protein 167 | 0.0146653 |
| AOC1 | amine oxidase, copper containing 1 | 0.013602 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.0132552 |
| AUTS2 | autism susceptibility candidate 2 | 0.0129823 |
| OLFM4 | olfactomedin 4 | 0.0121833 |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.0119588 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0114923 |
| LCN2 | lipocalin 2 | 0.0109452 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0108467 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0107886 |
| PODXL | podocalyxin-like | 0.0105719 |
| ITM2C | integral membrane protein 2C | 0.010005 |
| NEBL | nebulette | 0.00977325 |
| NRN1 | neuritin 1 | 0.00975241 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00972266 |
| KLK10 | kallikrein-related peptidase 10 | 0.0097056 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00970194 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00958191 |
| CST7 | cystatin F (leukocystatin) | 0.00950604 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00949897 |
| NSG1 | neuron specific gene family member 1 | 0.00946267 |
| PTHLH | parathyroid hormone-like hormone | 0.00935329 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00911305 |
| CAPN3 | calpain 3, (p94) | 0.00908001 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00902155 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00898048 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.00879582 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00852383 |
| DSG1 | desmoglein 1 | 0.0084161 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0084054 |
| PLP1 | proteolipid protein 1 | 0.00834446 |
| DIAPH2 | diaphanous-related formin 2 | 0.00832841 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00826469 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00818247 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00810283 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0080925 |
| CALB1 | calbindin 1, 28kDa | 0.00805407 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00801573 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00788611 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00788046 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00786837 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00782645 |
| QDPR | quinoid dihydropteridine reductase | 0.00769375 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00760419 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00759515 |
| CLIC5 | chloride intracellular channel 5 | 0.00756857 |
| RCAN1 | regulator of calcineurin 1 | 0.00748809 |
| LEFTY1 | left-right determination factor 1 | 0.00745295 |
| VWF | von Willebrand factor | 0.00744645 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00744361 |
| SELPLG | selectin P ligand | 0.0073976 |
| TMEM176A | transmembrane protein 176A | 0.00739477 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.0073591 |
| TSPAN8 | tetraspanin 8 | 0.00729466 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00724838 |
| GAB2 | GRB2-associated binding protein 2 | 0.00720061 |
| MARCKSL1 | MARCKS-like 1 | 0.00719001 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00718062 |
| KRT1 | keratin 1, type II | 0.00713357 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00712051 |
| HAS2 | hyaluronan synthase 2 | 0.00711382 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00710361 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.00709302 |
| S100A12 | S100 calcium binding protein A12 | 0.00707517 |
| ARG1 | arginase 1 | 0.00705692 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00697649 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00696412 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00689247 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00687887 |
| CALML3 | calmodulin-like 3 | 0.00687788 |
| GATA6 | GATA binding protein 6 | 0.00685933 |
| HTRA1 | HtrA serine peptidase 1 | 0.00685581 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00685027 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00683388 |
| DPEP1 | dipeptidase 1 (renal) | 0.00679643 |
| RGS5 | regulator of G-protein signaling 5 | 0.00678927 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.0067607 |
| CDA | cytidine deaminase | 0.0067606 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00674601 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00670181 |
| MAL | mal, T-cell differentiation protein | 0.00666513 |
| PGAP2 | post-GPI attachment to proteins 2 | 0.00665969 |
| MSLN | mesothelin | 0.00665915 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 0.00665748 |
| MMP8 | matrix metallopeptidase 8 | 0.00665387 |
| ACOT7 | acyl-CoA thioesterase 7 | 0.00665268 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00662889 |
| ZIC1 | Zic family member 1 | 0.00660418 |
| TKTL1 | transketolase-like 1 | 0.0065833 |
| FCGBP | Fc fragment of IgG binding protein | 0.00658282 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.00654845 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00653785 |
| IL2RG | interleukin 2 receptor, gamma | 0.00651106 |
| CFDP1 | craniofacial development protein 1 | 0.00649031 |
| S100P | S100 calcium binding protein P | 0.00648015 |
| RGCC | regulator of cell cycle | 0.00647992 |
| MGAM | maltase-glucoamylase | 0.00646641 |
| TYRP1 | tyrosinase-related protein 1 | 0.00645232 |
| XIC | X chromosome inactivation center | 0.00642661 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00640875 |
| EDN1 | endothelin 1 | 0.00638086 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00637741 |
| BIN1 | bridging integrator 1 | 0.00633341 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00631969 |
| BMP2 | bone morphogenetic protein 2 | 0.00628024 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0062558 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00624086 |
| FBXO11 | F-box protein 11 | 0.00623455 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.00622066 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00621695 |
| MX1 | MX dynamin-like GTPase 1 | 0.00619715 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00618752 |
| LAMC2 | laminin, gamma 2 | 0.00616398 |
| CD81 | CD81 molecule | 0.00616032 |
| C5ORF30 | chromosome 5 open reading frame 30 | 0.00613909 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.00613434 |
| CLTB | clathrin, light chain B | 0.00613156 |
| RNASET2 | ribonuclease T2 | 0.00613149 |
| FA2H | fatty acid 2-hydroxylase | 0.00613136 |
| GPM6A | glycoprotein M6A | 0.00609958 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00609954 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00606409 |
| FAM107A | family with sequence similarity 107, member A | 0.00606224 |
| CDK18 | cyclin-dependent kinase 18 | 0.00606108 |
| EDNRB | endothelin receptor type B | 0.00605603 |
| ACKR3 | atypical chemokine receptor 3 | 0.00605482 |
| PRKCQ | protein kinase C, theta | 0.00604217 |
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.00602736 |
| KLK6 | kallikrein-related peptidase 6 | 0.00602497 |
| CBFB | core-binding factor, beta subunit | 0.00601264 |
| ATP10B | ATPase, class V, type 10B | 0.00599793 |
| CD96 | CD96 molecule | 0.00594461 |
| DEFB1 | defensin, beta 1 | 0.00594055 |
| LOR | loricrin | 0.005926 |
| ZNF395 | zinc finger protein 395 | 0.00590715 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00590522 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00590521 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.00587222 |
| S100B | S100 calcium binding protein B | 0.00587222 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.00587111 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00584565 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00583731 |
| SOX17 | SRY (sex determining region Y)-box 17 | 0.0058368 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00581815 |
| OPHN1 | oligophrenin 1 | 0.00581273 |
| BPI | bactericidal/permeability-increasing protein | 0.00580055 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00579983 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00579374 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.00578906 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.00578138 |
| LIPG | lipase, endothelial | 0.00577547 |
| CSNK1E | casein kinase 1, epsilon | 0.00576715 |
| ANXA3 | annexin A3 | 0.00575111 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.0057118 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.00570715 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.00570565 |
| CDV3 | CDV3 homolog (mouse) | 0.00570117 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00568843 |
| ATF3 | activating transcription factor 3 | 0.00567934 |
| LRP2 | low density lipoprotein receptor-related protein 2 | 0.00567716 |
| CH25H | cholesterol 25-hydroxylase | 0.00567431 |
| EPS8L3 | EPS8-like 3 | 0.00567413 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00565477 |
| CTSV | cathepsin V | 0.00563623 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00562794 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.00562332 |
| ASPA | aspartoacylase | 0.005602 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.0055826 |
| FERMT1 | fermitin family member 1 | 0.005563 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00552118 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00551852 |
| UPB1 | ureidopropionase, beta | 0.00551556 |
| OPTN | optineurin | 0.00549547 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.00549142 |
| MSRB2 | methionine sulfoxide reductase B2 | 0.00548404 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00548262 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.00547716 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 0.0054598 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00545707 |
| PLS3 | plastin 3 | 0.00544728 |
| KIFAP3 | kinesin-associated protein 3 | 0.00544137 |
| CNTN1 | contactin 1 | 0.00542314 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00542155 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00541054 |
| CES1 | carboxylesterase 1 | 0.00540923 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.00539674 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0053905 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00537639 |
| TADA2A | transcriptional adaptor 2A | 0.00537329 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.00536409 |
| MSN | moesin | 0.00536213 |
| OSTF1 | osteoclast stimulating factor 1 | 0.00534512 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.00534369 |
| GOLGA8H | golgin A8 family, member H | 0.00534006 |
| DEFB4A | defensin, beta 4A | 0.00531228 |
| C21ORF91 | chromosome 21 open reading frame 91 | 0.00528209 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00528186 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0052622 |
| DSG3 | desmoglein 3 | 0.00525486 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00524546 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.00524398 |
| SP110 | SP110 nuclear body protein | 0.00524207 |
| AVEN | apoptosis, caspase activation inhibitor | 0.00523488 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.00523053 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00522994 |
| PLLP | plasmolipin | 0.00522991 |
| MLANA | melan-A | 0.00522771 |
| ZNF165 | zinc finger protein 165 | 0.00520646 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00520251 |
| CLC | Charcot-Leyden crystal galectin | 0.00518451 |
| PMP2 | peripheral myelin protein 2 | 0.00518004 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.00517974 |
| PITX3 | paired-like homeodomain 3 | 0.00517618 |
| DUSP7 | dual specificity phosphatase 7 | 0.00515921 |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.00515731 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0051469 |
| COG4 | component of oligomeric golgi complex 4 | 0.00512563 |
| GAS6 | growth arrest-specific 6 | 0.00511104 |
| GALC | galactosylceramidase | 0.0051073 |
| TSPAN3 | tetraspanin 3 | 0.00510097 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00509173 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0050911 |
| SAMHD1 | SAM domain and HD domain 1 | 0.00509091 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.00507682 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00507336 |
| MOAP1 | modulator of apoptosis 1 | 0.00506915 |
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 | 0.005058 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | 0.00505678 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0050533 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) | 0.00503953 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00503777 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 0.00503478 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase | 0.00503475 |
| NELL1 | NEL-like 1 (chicken) | 0.00502724 |
| KDR | kinase insert domain receptor | 0.00502243 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.0050065 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00500506 |
| PRSS8 | protease, serine, 8 | 0.00500473 |
| TFDP1 | transcription factor Dp-1 | 0.00500182 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0050014 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | 0.00500103 |
| SALL1 | spalt-like transcription factor 1 | 0.00498929 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00498902 |
| CTSZ | cathepsin Z | 0.00497296 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00497184 |
| OLFML2A | olfactomedin-like 2A | 0.00495811 |
| MMP3 | matrix metallopeptidase 3 | 0.0049369 |
| MUC13 | mucin 13, cell surface associated | 0.00493227 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00492734 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0167808 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.0136835 |
| APOD | apolipoprotein D | -0.0135257 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0135042 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0122077 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0122047 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.012044 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0118531 |
| STXBP2 | syntaxin binding protein 2 | -0.0118511 |
| TOX3 | TOX high mobility group box family member 3 | -0.0114106 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.0112361 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0111181 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.0109701 |
| MSMB | microseminoprotein, beta- | -0.0107185 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0105764 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0105391 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.0104269 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0102129 |
| KYNU | kynureninase | -0.00993796 |
| PMP22 | peripheral myelin protein 22 | -0.00980114 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00964785 |
| KRT7 | keratin 7, type II | -0.00961461 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00959608 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00934022 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00924873 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00924657 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00923458 |
| CPM | carboxypeptidase M | -0.0090921 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00908571 |
| OAT | ornithine aminotransferase | -0.00897626 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00896855 |
| KRT19 | keratin 19, type I | -0.00891719 |
| CLU | clusterin | -0.00890733 |
| METRN | meteorin, glial cell differentiation regulator | -0.00888194 |
| COG7 | component of oligomeric golgi complex 7 | -0.00885713 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00884816 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00859859 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | -0.00845925 |
| LOXL1 | lysyl oxidase-like 1 | -0.00843461 |
| CCNG2 | cyclin G2 | -0.00843171 |
| ASPN | asporin | -0.0083585 |
| BSG | basigin (Ok blood group) | -0.0083553 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00830781 |
| NPY | neuropeptide Y | -0.00828164 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0082329 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.0081734 |
| PERP | PERP, TP53 apoptosis effector | -0.00813495 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00810028 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00809527 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00809012 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00798816 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00796783 |
| APOB | apolipoprotein B | -0.00794435 |
| BAD | BCL2-associated agonist of cell death | -0.0079298 |
| CPE | carboxypeptidase E | -0.00789102 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | -0.00785564 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | -0.00780098 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0077828 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00774592 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00766312 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00760936 |
| SC5D | sterol-C5-desaturase | -0.00759497 |
| ZNF91 | zinc finger protein 91 | -0.00755937 |
| PSCA | prostate stem cell antigen | -0.00754031 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00752592 |
| PPL | periplakin | -0.00744605 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00743197 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00741637 |
| METTL7A | methyltransferase like 7A | -0.00738218 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | -0.00736342 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00734658 |
| PROM1 | prominin 1 | -0.00729879 |
| SPP1 | secreted phosphoprotein 1 | -0.00718884 |
| ABHD3 | abhydrolase domain containing 3 | -0.00718314 |
| HOXB2 | homeobox B2 | -0.00716614 |
| AHSG | alpha-2-HS-glycoprotein | -0.0071577 |
| COPE | coatomer protein complex, subunit epsilon | -0.00715192 |
| FADS3 | fatty acid desaturase 3 | -0.00713893 |
| NBEA | neurobeachin | -0.00710747 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00710226 |
| APOC1 | apolipoprotein C-I | -0.00708619 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0070642 |
| ANXA5 | annexin A5 | -0.00705178 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00699588 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00699569 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00699304 |
| AIM2 | absent in melanoma 2 | -0.00699285 |
| PCLAF | PCNA clamp associated factor | -0.00697403 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0069706 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00696975 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00691791 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.00691278 |
| STK39 | serine threonine kinase 39 | -0.0069119 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00691064 |
| PLAU | plasminogen activator, urokinase | -0.00686459 |
| H1-2 | H1.2 linker histone, cluster member | -0.00683806 |
| CSTA | cystatin A (stefin A) | -0.00679433 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00673792 |
| RRM2 | ribonucleotide reductase M2 | -0.00668871 |
| PFN2 | profilin 2 | -0.00668813 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00667271 |
| TMEM165 | transmembrane protein 165 | -0.00664052 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00663802 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00662272 |
| APOA2 | apolipoprotein A-II | -0.00661892 |
| TSPAN9 | tetraspanin 9 | -0.0066105 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00660286 |
| HBD | hemoglobin, delta | -0.0066002 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00658126 |
| PLIN1 | perilipin 1 | -0.00657619 |
| CTSH | cathepsin H | -0.00655842 |
| LYZ | lysozyme | -0.0065562 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | -0.00653655 |
| GAS1 | growth arrest-specific 1 | -0.00651571 |
| RGS13 | regulator of G-protein signaling 13 | -0.00650892 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00647026 |
| COMT | catechol-O-methyltransferase | -0.00644484 |
| CRIP2 | cysteine-rich protein 2 | -0.00641289 |
| KCTD5 | potassium channel tetramerization domain containing 5 | -0.00637432 |
| PGC | progastricsin (pepsinogen C) | -0.00637307 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00636859 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00636335 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00635741 |
| BEX1 | brain expressed, X-linked 1 | -0.00634448 |
| PDGFC | platelet derived growth factor C | -0.00634395 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | -0.00634205 |
| SQLE | squalene epoxidase | -0.00633696 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00632059 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | -0.00628686 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00626487 |
| C5ORF28 | chromosome 5 open reading frame 28 | -0.00624684 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00621379 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.00614421 |
| COL10A1 | collagen, type X, alpha 1 | -0.00613655 |
| AFP | alpha-fetoprotein | -0.00613502 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00613258 |
| TGFB1 | transforming growth factor, beta 1 | -0.00610213 |
| SYT17 | synaptotagmin XVII | -0.00608821 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.00607988 |
| RAB1A | RAB1A, member RAS oncogene family | -0.006071 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00606998 |
| HNMT | histamine N-methyltransferase | -0.00604125 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00603997 |
| RPL10 | ribosomal protein L10 | -0.00603703 |
| CNN3 | calponin 3, acidic | -0.00598345 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00596053 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.00595125 |
| TPD52L1 | tumor protein D52-like 1 | -0.00592402 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00591926 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00591873 |
| PDE8B | phosphodiesterase 8B | -0.00588077 |
| SLC38A6 | solute carrier family 38, member 6 | -0.00587922 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00587369 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.005871 |
| DUSP5 | dual specificity phosphatase 5 | -0.00586666 |
| PLD3 | phospholipase D family, member 3 | -0.00586468 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.0058627 |
| EMC3 | ER membrane protein complex subunit 3 | -0.00584889 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.00584335 |
| CST6 | cystatin E/M | -0.00583742 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.0058201 |
| MMP7 | matrix metallopeptidase 7 | -0.00579192 |
| C3 | complement component 3 | -0.00578638 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00578415 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00577656 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.00577119 |
| MAGEB2 | melanoma antigen family B2 | -0.00576726 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00576649 |
| EMP3 | epithelial membrane protein 3 | -0.00576235 |
| HIST3H2A | histone cluster 3, H2a | -0.00575431 |
| SCGN | secretagogin, EF-hand calcium binding protein | -0.00574632 |
| CHI3L2 | chitinase 3-like 2 | -0.00574503 |
| FADS1 | fatty acid desaturase 1 | -0.0057434 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00571476 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00569087 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.00569064 |
| LTF | lactotransferrin | -0.00568651 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00568626 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | -0.00568349 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -0.00567953 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00567115 |
| AHR | aryl hydrocarbon receptor | -0.00566056 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00565554 |
| GLS | glutaminase | -0.0056458 |
| RXRA | retinoid X receptor, alpha | -0.00564086 |
| CD37 | CD37 molecule | -0.00559463 |
| OSMR | oncostatin M receptor | -0.00559414 |
| SGMS1 | sphingomyelin synthase 1 | -0.00557996 |
| THUMPD1 | THUMP domain containing 1 | -0.00557435 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.00556219 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 | -0.00554664 |
| PGRMC2 | progesterone receptor membrane component 2 | -0.0055364 |
| FASN | fatty acid synthase | -0.00551234 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00549778 |
| CPD | carboxypeptidase D | -0.00549146 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 | -0.00548864 |
| PLTP | phospholipid transfer protein | -0.00548343 |
| JUNB | jun B proto-oncogene | -0.00548002 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.00547328 |
| MAOA | monoamine oxidase A | -0.00545715 |
| MED13 | mediator complex subunit 13 | -0.00545531 |
| TFEC | transcription factor EC | -0.00543873 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00541267 |
| RIN2 | Ras and Rab interactor 2 | -0.00537965 |
| RIOK3 | RIO kinase 3 | -0.00537495 |
| CLIC2 | chloride intracellular channel 2 | -0.00537125 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00535197 |
| CYBC1 | cytochrome b-245 chaperone 1 | -0.00534694 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00533207 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00533018 |
| BLNK | B-cell linker | -0.0053269 |
| IL17RC | interleukin 17 receptor C | -0.00532545 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0053243 |
| CD84 | CD84 molecule | -0.00531994 |
| CADM1 | cell adhesion molecule 1 | -0.00531501 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00530929 |
| CLDN4 | claudin 4 | -0.00529631 |
| LRRC40 | leucine rich repeat containing 40 | -0.00528934 |
| CIDEC | cell death-inducing DFFA-like effector c | -0.0052869 |
| ISCA1 | iron-sulfur cluster assembly 1 | -0.00528131 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | -0.00527668 |
| PTK2 | protein tyrosine kinase 2 | -0.00526248 |
| TNS3 | tensin 3 | -0.00525472 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | -0.00525296 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.00525194 |
| ZNF512B | zinc finger protein 512B | -0.00522516 |
| KRT8 | keratin 8, type II | -0.00521633 |
| CXORF40A | chromosome X open reading frame 40A | -0.00517765 |
| MT1F | metallothionein 1F | -0.00516726 |
| MEIS2 | Meis homeobox 2 | -0.00516559 |
| RAPSN | receptor-associated protein of the synapse | -0.00515791 |
| ZNF544 | zinc finger protein 544 | -0.00515382 |
| ATG7 | autophagy related 7 | -0.00511843 |
| NPTXR | neuronal pentraxin receptor | -0.0051109 |
| NCKAP1 | NCK-associated protein 1 | -0.00510991 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.00510571 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00510241 |
| CDC20 | cell division cycle 20 | -0.00509422 |
| UPK1B | uroplakin 1B | -0.00509343 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00508135 |
| FN1 | fibronectin 1 | -0.00507431 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | -0.00507142 |
| SV2B | synaptic vesicle glycoprotein 2B | -0.00506406 |
| DCLK1 | doublecortin-like kinase 1 | -0.00505164 |
| KRT18 | keratin 18, type I | -0.00504784 |
| MYBPC1 | myosin binding protein C, slow type | -0.0050468 |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 | -0.00504153 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00503507 |
