CD47 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description CD47 molecule|This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 961)
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Genes

325 genes differentially expressed following the CD47 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
RAET1E retinoic acid early transcript 1E 3.32753
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 3.32753
PON1 paraoxonase 1 3.32753
PRODH2 proline dehydrogenase (oxidase) 2 3.32753
LRRC14B leucine rich repeat containing 14B 3.32753
DUSP10 dual specificity phosphatase 10 3.32753
CCL5 chemokine (C-C motif) ligand 5 3.32753
CD300A CD300a molecule 3.32753
DMRTC1B DMRT-like family C1B 3.32753
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 3.32753
MAGEA2 melanoma antigen family A2 3.32753
NXPH4 neurexophilin 4 3.32753
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 3.32753
WEE2 WEE1 homolog 2 (S. pombe) 3.32753
TPBGL trophoblast glycoprotein-like 3.32753
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 3.32753
NPAP1 nuclear pore associated protein 1 3.32753
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 3.32753
DUXB double homeobox B 3.32753
KNG1 kininogen 1 3.32753
TMEM176A transmembrane protein 176A 3.32753
RFPL2 ret finger protein-like 2 3.32753
OTUD6A OTU deubiquitinase 6A 3.32753
TRPV5 transient receptor potential cation channel, subfamily V, member 5 3.32753
C2ORF78 chromosome 2 open reading frame 78 3.32753
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 3.32753
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 3.32753
HIC1 hypermethylated in cancer 1 3.32753
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 3.32753
IL18R1 interleukin 18 receptor 1 3.32753
OR56A5 olfactory receptor, family 56, subfamily A, member 5 3.32753
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 3.32753
OR6J1 olfactory receptor, family 6, subfamily J, member 1 (gene/pseudogene) 3.32753
HMX3 H6 family homeobox 3 3.32753
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 3.32753
RAB20 RAB20, member RAS oncogene family 3.32753
ACTL7B actin-like 7B 3.32753
LGI1 leucine-rich, glioma inactivated 1 3.32753
GMNC geminin coiled-coil domain containing 3.32753
RIMBP3B RIMS binding protein 3B 3.32753
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative) 3.32753
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 3.32753
JCHAIN joining chain of multimeric IgA and IgM 3.32753
CLEC14A C-type lectin domain family 14, member A 3.32753
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 3.32753
LOC107986837 uncharacterized LOC107986837 3.32753
ANKRD40CL ANKRD40 C-terminal like 3.32753
SMIM38 small integral membrane protein 38 3.32753
H3-5 H3.5 histone 3.32753
LTB4R2 leukotriene B4 receptor 2 3.32753
HTRA4 HtrA serine peptidase 4 3.32753
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 3.32753
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 3.32753
MIOX myo-inositol oxygenase 3.32753
CFC1 cripto, FRL-1, cryptic family 1 3.32753
MINAR1 membrane integral NOTCH2 associated receptor 1 3.32753
TAFA3 TAFA chemokine like family member 3 3.32753
OR56B2 olfactory receptor family 56 subfamily B member 2 3.32753
ANKRD42-DT ANKRD42 divergent transcript 3.32753
C17ORF113 chromosome 17 open reading frame 113 3.32753
GREP1 glycine rich extracellular protein 1 3.32753
SMIM43 small integral membrane protein 43 3.32753
OR52P1 olfactory receptor family 52 subfamily P member 1 (gene/pseudogene) 3.32753
LHFPL7 LHFPL tetraspan subfamily member 7 3.32753
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 3.32753
VXN vexin 3.32753
GPR37L1 G protein-coupled receptor 37 like 1 3.32753
GATA1 GATA binding protein 1 (globin transcription factor 1) 3.32753
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 3.32753
CLDN1 claudin 1 3.32753
TUBA3D tubulin, alpha 3d 3.32753
LTBP2 latent transforming growth factor beta binding protein 2 3.32753
PTPRQ protein tyrosine phosphatase, receptor type, Q 3.32753
TSSC4 tumor suppressing subtransferable candidate 4 3.32753
RHOXF2 Rhox homeobox family, member 2 3.32753
GDA guanine deaminase 3.32753
LIPK lipase, family member K 3.32753
ATP13A4 ATPase type 13A4 3.32753
ITK IL2-inducible T-cell kinase 3.32753
CD48 CD48 molecule 3.32753
ZNF350 zinc finger protein 350 3.32753
TACR2 tachykinin receptor 2 3.32753
S100B S100 calcium binding protein B 3.32753
ARMS2 age-related maculopathy susceptibility 2 3.32753
KLRF1 killer cell lectin-like receptor subfamily F, member 1 3.32753
TFEC transcription factor EC 3.32753
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 3.32753
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 3.32753
MSX1 msh homeobox 1 3.32753
ISM2 isthmin 2 3.32753
CDHR5 cadherin-related family member 5 3.32753
PTGDR prostaglandin D2 receptor (DP) 3.32753
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 3.32753
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 3.32753
MC5R melanocortin 5 receptor 3.32753
STMND1 stathmin domain containing 1 3.32753
SUN3 Sad1 and UNC84 domain containing 3 3.32753
PRRX1 paired related homeobox 1 3.32753
ADGRF1 adhesion G protein-coupled receptor F1 3.32753
PDZRN4 PDZ domain containing ring finger 4 3.32753
ITGAD integrin, alpha D 3.32753
GTF2A1L general transcription factor IIA, 1-like 3.32753
PXT1 peroxisomal, testis specific 1 3.32753
HHIPL2 HHIP-like 2 3.32753
ZFP92 ZFP92 zinc finger protein 3.32753
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 3.32753
SPRN shadow of prion protein homolog (zebrafish) 3.32753
TBC1D10C TBC1 domain family, member 10C 3.32753
GOLGA6C golgin A6 family, member C 3.32753
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 3.32753
DYDC1 DPY30 domain containing 1 3.32753
SPATA4 spermatogenesis associated 4 3.32753
PAGE4 P antigen family, member 4 (prostate associated) 3.32753
MAB21L1 mab-21-like 1 (C. elegans) 3.32753
KCNK4 potassium channel, two pore domain subfamily K, member 4 3.32753
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 3.32753
CCDC152 coiled-coil domain containing 152 3.32753
PRF1 perforin 1 (pore forming protein) 3.32753
PCDHGA4 protocadherin gamma subfamily A, 4 3.32753
IL1B interleukin 1, beta 3.32753
PLEKHS1 pleckstrin homology domain containing, family S member 1 3.32753
HLA-DOB major histocompatibility complex, class II, DO beta 3.32753
SPEF1 sperm flagellar 1 3.32753
PCDHGA12 protocadherin gamma subfamily A, 12 3.32753
VPREB3 pre-B lymphocyte 3 3.32753
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 3.32753
AMPD1 adenosine monophosphate deaminase 1 3.32753
ABRA actin binding Rho activating protein 3.32753
MEIG1 meiosis/spermiogenesis associated 1 3.32753
PLA2G5 phospholipase A2, group V 3.32753
OR52N1 olfactory receptor, family 52, subfamily N, member 1 3.32753
SPDEF SAM pointed domain containing ETS transcription factor 3.32753
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 3.32753
GPR78 G protein-coupled receptor 78 3.32753
PODN podocan 3.32753
PRSS21 protease, serine, 21 (testisin) 3.32753
PHACTR3 phosphatase and actin regulator 3 3.32753
RAD51AP2 RAD51 associated protein 2 3.32753
NLRP5 NLR family, pyrin domain containing 5 3.32753
TH tyrosine hydroxylase 3.32753
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 3.32753
AMN amnion associated transmembrane protein 3.32753
SPHKAP SPHK1 interactor, AKAP domain containing 3.32753
TEX38 testis expressed 38 3.32753
C4ORF36 chromosome 4 open reading frame 36 3.32753
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 3.32753
ALOX12B arachidonate 12-lipoxygenase, 12R type 3.32753
LPO lactoperoxidase 3.32753
AOC1 amine oxidase, copper containing 1 3.32753
MARCHF10 membrane associated ring-CH-type finger 10 3.25961
TMC3 transmembrane channel-like 3 3.25961
EPHB1 EPH receptor B1 3.24136
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 3.23122
TOX3 TOX high mobility group box family member 3 3.11339
CA11 carbonic anhydrase XI 3.07313
CSRNP2 cysteine-serine-rich nuclear protein 2 2.97497
PCNX4 pecanex 4 2.96134
HELZ2 helicase with zinc finger 2, transcriptional coactivator 2.91179
HJURP Holliday junction recognition protein 2.87212
UGP2 UDP-glucose pyrophosphorylase 2 2.86863
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 2.73965
TRIQK triple QxxK/R motif containing 2.7238
PCDH12 protocadherin 12 2.63599
EFNB2 ephrin-B2 2.60877
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 2.59758
YEATS2 YEATS domain containing 2 2.58977
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1 2.56836
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 2.55253
FARSA phenylalanyl-tRNA synthetase, alpha subunit 2.55129
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.4959
STX3 syntaxin 3 2.44529
MRPL19 mitochondrial ribosomal protein L19 2.44306
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 2.43033
TANGO6 transport and golgi organization 6 homolog (Drosophila) 2.43026
ANXA2 annexin A2 2.4299
MSR1 macrophage scavenger receptor 1 2.4299
ADAM11 ADAM metallopeptidase domain 11 2.4299
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 2.4299
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 2.4299
FBXL19 F-box and leucine-rich repeat protein 19 2.4299
ECT2L epithelial cell transforming 2 like 2.4299
MYT1L myelin transcription factor 1-like 2.4299
CEP63 centrosomal protein 63kDa 2.4299
OXSM 3-oxoacyl-ACP synthase, mitochondrial 2.4299
XK X-linked Kx blood group 2.4299
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 2.4299
STAB2 stabilin 2 2.4299
INHBE inhibin, beta E 2.4299
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 2.42664
ZFAND6 zinc finger, AN1-type domain 6 2.41645
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 2.3682
ZNF530 zinc finger protein 530 2.35623
GNMT glycine N-methyltransferase 2.33844
SRRT serrate, RNA effector molecule 2.32791
ZNF638 zinc finger protein 638 2.31013
ASIP agouti signaling protein 2.31013
ZNHIT3 zinc finger, HIT-type containing 3 2.30091
GIPC1 GIPC PDZ domain containing family, member 1 2.29626
WIPF3 WAS/WASL interacting protein family, member 3 2.29201
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 2.24898
TNNT2 troponin T type 2 (cardiac) 2.2489
MTAP methylthioadenosine phosphorylase 2.23403
ODAD3 outer dynein arm docking complex subunit 3 2.22574
PPCDC phosphopantothenoylcysteine decarboxylase 2.2188
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 2.2188
GLO1 glyoxalase I 2.21721
HIF3A hypoxia inducible factor 3, alpha subunit 2.20033
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 2.1711
PPOX protoporphyrinogen oxidase 2.1373
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 2.13134
DUS2 dihydrouridine synthase 2 2.12113
SPC24 SPC24, NDC80 kinetochore complex component 2.11296
CCDC120 coiled-coil domain containing 120 2.11027
PLD3 phospholipase D family, member 3 2.10696
CAVIN4 caveolae associated protein 4 2.10478
TDRD7 tudor domain containing 7 2.0418
CCNT1 cyclin T1 2.037
TPO thyroid peroxidase 2.037
SH3BP2 SH3-domain binding protein 2 2.03237

decreased expression

Symbol Name Standardized Value
RABL2B RAB, member of RAS oncogene family-like 2B -3.32753
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 -3.32753
ZSCAN22 zinc finger and SCAN domain containing 22 -3.32753
CBY3 chibby homolog 3 (Drosophila) -3.32753
CXCR4 chemokine (C-X-C motif) receptor 4 -3.32753
HYAL1 hyaluronoglucosaminidase 1 -3.32753
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 -3.32753
TRIM17 tripartite motif containing 17 -3.32753
SYNPO synaptopodin -3.32753
CYBRD1 cytochrome b reductase 1 -3.32753
USP21 ubiquitin specific peptidase 21 -3.32753
ZNF823 zinc finger protein 823 -3.32753
ZNF449 zinc finger protein 449 -3.32753
PVALB parvalbumin -3.32753
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -3.24235
PUS10 pseudouridylate synthase 10 -3.23122
CCNH cyclin H -3.18186
LHX1 LIM homeobox 1 -3.08757
OC90 otoconin 90 -3.08757
EYA4 EYA transcriptional coactivator and phosphatase 4 -3.08757
IQCJ IQ motif containing J -3.08757
EMCN endomucin -3.08757
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 -3.08757
TMPRSS4 transmembrane protease, serine 4 -3.08757
SPDYE17 speedy/RINGO cell cycle regulator family member E17 -3.08757
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 -3.08757
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -3.08757
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -3.08757
GJA4 gap junction protein, alpha 4, 37kDa -3.08757
BTC betacellulin -3.08757
HES3 hes family bHLH transcription factor 3 -3.08757
RRAD Ras-related associated with diabetes -3.08757
MTTP microsomal triglyceride transfer protein -3.08757
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit -3.08757
MEIOB meiosis specific with OB domains -3.08757
C17ORF107 chromosome 17 open reading frame 107 -3.08757
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 -3.08757
HCLS1 hematopoietic cell-specific Lyn substrate 1 -3.08757
DGCR6 DiGeorge syndrome critical region gene 6 -3.08757
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -3.08757
CFP complement factor properdin -3.08757
MYF6 myogenic factor 6 (herculin) -3.08757
NKAPD1 NKAP domain containing 1 -2.9585
NRG2 neuregulin 2 -2.94213
RGPD6 RANBP2-like and GRIP domain containing 6 -2.77963
VSTM4 V-set and transmembrane domain containing 4 -2.74982
BCAP29 B-cell receptor-associated protein 29 -2.64683
RUFY3 RUN and FYVE domain containing 3 -2.63599
GATD1 glutamine amidotransferase class 1 domain containing 1 -2.63599
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) -2.60931
FSIP1 fibrous sheath interacting protein 1 -2.56579
ITGB5 integrin, beta 5 -2.54203
S100A16 S100 calcium binding protein A16 -2.52915
TTN titin -2.50143
GAS7 growth arrest-specific 7 -2.48056
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -2.48056
OTUD4 OTU deubiquitinase 4 -2.46153
LAMA4 laminin, alpha 4 -2.44306
RND1 Rho family GTPase 1 -2.42977
SLCO5A1 solute carrier organic anion transporter family, member 5A1 -2.41468
APTX aprataxin -2.41358
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -2.40497
TRHDE thyrotropin-releasing hormone degrading enzyme -2.36415
ZNF514 zinc finger protein 514 -2.31013
IFNAR2 interferon (alpha, beta and omega) receptor 2 -2.30091
HBQ1 hemoglobin, theta 1 -2.29201
WDR18 WD repeat domain 18 -2.25319
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -2.24969
FOXO1 forkhead box O1 -2.24679
LPL lipoprotein lipase -2.24172
TUBB4A tubulin, beta 4A class IVa -2.23946
ZNF469 zinc finger protein 469 -2.23946
KIAA2012 KIAA2012 -2.23946
ATP8B4 ATPase, class I, type 8B, member 4 -2.23946
PDCD6 programmed cell death 6 -2.22574
TLL2 tolloid-like 2 -2.20033
RAB34 RAB34, member RAS oncogene family -2.19157
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -2.17261
RIN3 Ras and Rab interactor 3 -2.15936
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -2.15936
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) -2.15936
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit -2.15936
CFAP410 cilia and flagella associated protein 410 -2.14603
FBLN5 fibulin 5 -2.14603
YME1L1 YME1-like 1 ATPase -2.1437
COA6 cytochrome c oxidase assembly factor 6 -2.1434
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -2.14118
ZC4H2 zinc finger, C4H2 domain containing -2.14118
TMEM47 transmembrane protein 47 -2.14118
RNF103 ring finger protein 103 -2.1386
ACSS1 acyl-CoA synthetase short-chain family member 1 -2.11881
MYO3B myosin IIIB -2.11881
ZNF365 zinc finger protein 365 -2.11881
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor -2.09516
ZNF200 zinc finger protein 200 -2.07366
NGDN neuroguidin, EIF4E binding protein -2.07172
GYPC glycophorin C (Gerbich blood group) -2.06691
ARL2BP ADP-ribosylation factor-like 2 binding protein -2.06249
NSMCE3 NSE3 homolog, SMC5-SMC6 complex component -2.04483
CAV1 caveolin 1, caveolae protein, 22kDa -2.03314
ANO8 anoctamin 8 -2.02066
TMUB2 transmembrane and ubiquitin-like domain containing 2 -2.02066
STARD7 StAR-related lipid transfer (START) domain containing 7 -2.02066
SFXN4 sideroflexin 4 -2.0159
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) -2.01416
SOX2 SRY (sex determining region Y)-box 2 -2.01271