CD53 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description CD53 molecule|The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 963)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CD53
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Genes

58 co-expressed genes for CD53 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
B2M beta-2-microglobulin
C17ORF62 chromosome 17 open reading frame 62
CD48 CD48 molecule
CD53 CD53 molecule
CORO1A coronin, actin binding protein, 1A
CORO7 coronin 7
CRLF3 cytokine receptor-like factor 3
CSK c-src tyrosine kinase
CYTIP cytohesin 1 interacting protein
DOCK2 dedicator of cytokinesis 2
ELF4 E74-like factor 4 (ets domain transcription factor)
FMNL1 formin-like 1
FXYD5 FXYD domain containing ion transport regulator 5
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPSM3 G-protein signaling modulator 3
GRK6 G protein-coupled receptor kinase 6
HCLS1 hematopoietic cell-specific Lyn substrate 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
IFI16 interferon, gamma-inducible protein 16
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
LAPTM5 lysosomal protein transmembrane 5
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIMD2 LIM domain containing 2
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LSP1 lymphocyte-specific protein 1
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MYD88 myeloid differentiation primary response 88
OSTF1 osteoclast stimulating factor 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PHF11 PHD finger protein 11
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SASH3 SAM and SH3 domain containing 3
SELL selectin L
SP110 SP110 nuclear body protein
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TRIM22 tripartite motif containing 22
VAV1 vav 1 guanine nucleotide exchange factor
WAS Wiskott-Aldrich syndrome
WIPF1 WAS/WASL interacting protein family, member 1
ZCCHC6 zinc finger, CCHC domain containing 6