| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | CD59 molecule, complement regulatory protein|This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 966) |
| External Link | https://ncbi.nlm.nih.gov/gene/966 |
| Similar Terms | |
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498 genes differentially expressed following the CD59 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.0142423 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0115095 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0094053 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00916996 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00915341 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00910202 |
| SFN | stratifin | 0.00891558 |
| SPRR1B | small proline-rich protein 1B | 0.00870962 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00868874 |
| HOPX | HOP homeobox | 0.00863532 |
| CCN3 | cellular communication network factor 3 | 0.00860492 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0083739 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00832648 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00826672 |
| SPRR2B | small proline-rich protein 2B | 0.00805978 |
| KRT6A | keratin 6A, type II | 0.00782801 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00777682 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | 0.00770068 |
| CD320 | CD320 molecule | 0.00745155 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00734103 |
| MICALL1 | MICAL-like 1 | 0.00732931 |
| ADIRF | adipogenesis regulatory factor | 0.00726637 |
| KIF20A | kinesin family member 20A | 0.00724746 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00719955 |
| KRT17 | keratin 17, type I | 0.00718471 |
| RHOB | ras homolog family member B | 0.00717494 |
| S100A2 | S100 calcium binding protein A2 | 0.00711219 |
| RXRA | retinoid X receptor, alpha | 0.00710224 |
| CLU | clusterin | 0.00706501 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00695426 |
| NNT | nicotinamide nucleotide transhydrogenase | 0.00688535 |
| KRT16 | keratin 16, type I | 0.00687963 |
| KRT14 | keratin 14, type I | 0.00677246 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00670241 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.00665981 |
| ELP1 | elongator acetyltransferase complex subunit 1 | 0.00665547 |
| BCHE | butyrylcholinesterase | 0.00658092 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00656761 |
| IL32 | interleukin 32 | 0.0065654 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00653109 |
| CD14 | CD14 molecule | 0.00650199 |
| LUM | lumican | 0.00644313 |
| ANKRD10 | ankyrin repeat domain 10 | 0.00639867 |
| CD93 | CD93 molecule | 0.00638052 |
| FBLN1 | fibulin 1 | 0.00634726 |
| SPRR1A | small proline-rich protein 1A | 0.00632601 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00629287 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00625693 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00622471 |
| ASPN | asporin | 0.00622471 |
| TCTA | T-cell leukemia translocation altered | 0.00618534 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00617351 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00614409 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.00613546 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00610968 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00610668 |
| RAB38 | RAB38, member RAS oncogene family | 0.0061053 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.00610268 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00609791 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00606657 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00602941 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00601629 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.0060067 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00599799 |
| CALML5 | calmodulin-like 5 | 0.0059187 |
| ACKR3 | atypical chemokine receptor 3 | 0.00587699 |
| KRT1 | keratin 1, type II | 0.00587552 |
| DSG1 | desmoglein 1 | 0.00587261 |
| CFD | complement factor D (adipsin) | 0.00584525 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00584377 |
| PRDX2 | peroxiredoxin 2 | 0.00579865 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00579656 |
| DCLK1 | doublecortin-like kinase 1 | 0.00574002 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00573691 |
| PPL | periplakin | 0.00570757 |
| PRDX4 | peroxiredoxin 4 | 0.00566395 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00565293 |
| KIF14 | kinesin family member 14 | 0.00560359 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.00559664 |
| PMM2 | phosphomannomutase 2 | 0.00557343 |
| IRF8 | interferon regulatory factor 8 | 0.00556117 |
| ACTB | actin, beta | 0.00555522 |
| SFTPB | surfactant protein B | 0.00551797 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.00550943 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00549931 |
| MMP2 | matrix metallopeptidase 2 | 0.00548535 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00547427 |
| FAM13A | family with sequence similarity 13, member A | 0.00547419 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00544229 |
| KRT6B | keratin 6B, type II | 0.00544175 |
| RCAN2 | regulator of calcineurin 2 | 0.00542638 |
| CHN1 | chimerin 1 | 0.0054088 |
| PLA1A | phospholipase A1 member A | 0.00540326 |
| PMF1 | polyamine-modulated factor 1 | 0.00539223 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00534042 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic | 0.00533501 |
| TYMP | thymidine phosphorylase | 0.00533152 |
| CST3 | cystatin C | 0.00531284 |
| ITGA7 | integrin, alpha 7 | 0.00529258 |
| NIT1 | nitrilase 1 | 0.00528047 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00527221 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.00524547 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00523186 |
| PCLAF | PCNA clamp associated factor | 0.00522251 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0051897 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.00517617 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma | 0.00516581 |
| ARG2 | arginase 2 | 0.0051559 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.00515113 |
| PGF | placental growth factor | 0.0051473 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | 0.00513327 |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.00511412 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00508601 |
| TBX3 | T-box 3 | 0.0050818 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00507225 |
| PAGE4 | P antigen family, member 4 (prostate associated) | 0.00506507 |
| PLXND1 | plexin D1 | 0.00505971 |
| ADIPOR2 | adiponectin receptor 2 | 0.00505208 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00504381 |
| KLF13 | Kruppel-like factor 13 | 0.00503789 |
| TMEM106C | transmembrane protein 106C | 0.00503437 |
| PMP22 | peripheral myelin protein 22 | 0.00501437 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0049901 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.00498734 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | 0.00498303 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00498282 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.00496876 |
| NXN | nucleoredoxin | 0.00496407 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00495465 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00493407 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00493045 |
| RHOA | ras homolog family member A | 0.00491662 |
| TMEM45A | transmembrane protein 45A | 0.00490327 |
| RASL12 | RAS-like, family 12 | 0.00489604 |
| ANGEL2 | angel homolog 2 (Drosophila) | 0.00489045 |
| EDNRB | endothelin receptor type B | 0.00488716 |
| CBX6 | chromobox homolog 6 | 0.00487947 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.00486551 |
| SETD5 | SET domain containing 5 | 0.00485339 |
| CD163 | CD163 molecule | 0.00484982 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00484259 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | 0.0048337 |
| EDRF1 | erythroid differentiation regulatory factor 1 | 0.00483045 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00481539 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | 0.0047852 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00476548 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00474603 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00473627 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00470268 |
| ARL5A | ADP-ribosylation factor-like 5A | 0.00469883 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00468459 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00468294 |
| EMP3 | epithelial membrane protein 3 | 0.00467235 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00465999 |
| RPA3 | replication protein A3, 14kDa | 0.00464865 |
| GRB14 | growth factor receptor-bound protein 14 | 0.00463548 |
| ACADL | acyl-CoA dehydrogenase, long chain | 0.00463163 |
| BAG2 | BCL2-associated athanogene 2 | 0.00461212 |
| COPS7A | COP9 signalosome subunit 7A | 0.00459807 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.00458461 |
| LYST | lysosomal trafficking regulator | 0.00457781 |
| FZD5 | frizzled class receptor 5 | 0.0045773 |
| DSC2 | desmocollin 2 | 0.00457268 |
| FAM3C | family with sequence similarity 3, member C | 0.00457148 |
| CTSV | cathepsin V | 0.00456447 |
| CADM1 | cell adhesion molecule 1 | 0.00456139 |
| DSG3 | desmoglein 3 | 0.00455423 |
| SETBP1 | SET binding protein 1 | 0.00455097 |
| MRPS28 | mitochondrial ribosomal protein S28 | 0.00454702 |
| OLFM1 | olfactomedin 1 | 0.00454243 |
| CEP55 | centrosomal protein 55kDa | 0.00453331 |
| SPEN | spen family transcriptional repressor | 0.00452541 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.00449957 |
| TCF4 | transcription factor 4 | 0.00448965 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | 0.0044875 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00447641 |
| CDA | cytidine deaminase | 0.00446019 |
| FASTKD3 | FAST kinase domains 3 | 0.00445703 |
| ZBED1 | zinc finger, BED-type containing 1 | 0.00445333 |
| DSC1 | desmocollin 1 | 0.00443793 |
| CHKB | choline kinase beta | 0.00443556 |
| MGP | matrix Gla protein | 0.00443428 |
| FGF13 | fibroblast growth factor 13 | 0.00442726 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.00442579 |
| CALML3 | calmodulin-like 3 | 0.0044193 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.00438002 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00437756 |
| TP63 | tumor protein p63 | 0.00436646 |
| AIM2 | absent in melanoma 2 | 0.00436614 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00436612 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00436555 |
| IVL | involucrin | 0.00435452 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00435351 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.00434764 |
| NEFH | neurofilament, heavy polypeptide | 0.00434693 |
| REV1 | REV1, polymerase (DNA directed) | 0.0043453 |
| TTN | titin | 0.00433695 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 0.00432275 |
| RUFY3 | RUN and FYVE domain containing 3 | 0.00431701 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00431186 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00429199 |
| CBR4 | carbonyl reductase 4 | 0.00428726 |
| TMEM204 | transmembrane protein 204 | 0.00428458 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00427669 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.00427633 |
| LIMA1 | LIM domain and actin binding 1 | 0.00427507 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.00425687 |
| CREB1 | cAMP responsive element binding protein 1 | 0.00425613 |
| GSTT1 | glutathione S-transferase theta 1 | 0.0042536 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00424955 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | 0.00424642 |
| RAD23A | RAD23 homolog A (S. cerevisiae) | 0.00424424 |
| SACM1L | SAC1 suppressor of actin mutations 1-like (yeast) | 0.0042423 |
| MEST | mesoderm specific transcript | 0.00423771 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00423279 |
| CCNL2 | cyclin L2 | 0.00423003 |
| IFI30 | interferon, gamma-inducible protein 30 | 0.0042159 |
| CELP | carboxyl ester lipase pseudogene | 0.00421015 |
| APOD | apolipoprotein D | 0.00420525 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.00419999 |
| S100A4 | S100 calcium binding protein A4 | 0.00419905 |
| CDSN | corneodesmosin | 0.00419765 |
| METTL17 | methyltransferase like 17 | 0.0041838 |
| RBM23 | RNA binding motif protein 23 | 0.00418248 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.0041774 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00417138 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00416545 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.00416395 |
| SEPTIN2 | septin 2 | 0.00415841 |
| MTSS1 | metastasis suppressor 1 | 0.00415066 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.00414364 |
| MIR22HG | MIR22 host gene | 0.00412659 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00412406 |
| PPAP2A | phosphatidic acid phosphatase type 2A | 0.00412336 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.00412333 |
| MCM5 | minichromosome maintenance complex component 5 | 0.00411842 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.00411835 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00411774 |
| PRAME | preferentially expressed antigen in melanoma | 0.004111 |
| MED13 | mediator complex subunit 13 | 0.00410761 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.00409798 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0040893 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00408543 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0040828 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00408275 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | 0.00408096 |
| CENPX | centromere protein X | 0.00408088 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 0.00408076 |
| YBX3 | Y box binding protein 3 | 0.00407497 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | -0.0133149 |
| S100P | S100 calcium binding protein P | -0.0127774 |
| HTRA1 | HtrA serine peptidase 1 | -0.0127526 |
| KRT19 | keratin 19, type I | -0.0125609 |
| NEBL | nebulette | -0.0114399 |
| COG7 | component of oligomeric golgi complex 7 | -0.0110073 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00986636 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00967777 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00958751 |
| FCGBP | Fc fragment of IgG binding protein | -0.0092747 |
| PEG3 | paternally expressed 3 | -0.00904866 |
| EPCAM | epithelial cell adhesion molecule | -0.00903558 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00893915 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00887167 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00884801 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00882518 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00882166 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00872815 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00852582 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00824335 |
| RGS4 | regulator of G-protein signaling 4 | -0.00820911 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00819499 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00787493 |
| BAX | BCL2-associated X protein | -0.00765303 |
| WWC1 | WW and C2 domain containing 1 | -0.00761658 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00759058 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00758283 |
| SCG5 | secretogranin V | -0.0075376 |
| PITX3 | paired-like homeodomain 3 | -0.00748199 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00747998 |
| RGS10 | regulator of G-protein signaling 10 | -0.00744392 |
| FGF1 | fibroblast growth factor 1 (acidic) | -0.00739698 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | -0.00724847 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -0.00721896 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00718981 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.0070958 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00706773 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0070109 |
| THBS1 | thrombospondin 1 | -0.00700539 |
| THBS2 | thrombospondin 2 | -0.00699764 |
| CD44 | CD44 molecule (Indian blood group) | -0.00697382 |
| CLDN8 | claudin 8 | -0.00697211 |
| ADD3 | adducin 3 (gamma) | -0.00696177 |
| CLC | Charcot-Leyden crystal galectin | -0.00693948 |
| RNASET2 | ribonuclease T2 | -0.00691963 |
| AOC1 | amine oxidase, copper containing 1 | -0.00688517 |
| TGFA | transforming growth factor, alpha | -0.00688069 |
| G0S2 | G0/G1 switch 2 | -0.00684508 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00682906 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00680501 |
| ANXA1 | annexin A1 | -0.0068013 |
| DOK5 | docking protein 5 | -0.0067893 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -0.00671003 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.00667119 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.0066696 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -0.00664789 |
| VNN1 | vanin 1 | -0.00662583 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00659121 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00658513 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00656414 |
| AK4 | adenylate kinase 4 | -0.00656082 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00649893 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.00647037 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00647024 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.0064679 |
| MLF1 | myeloid leukemia factor 1 | -0.00644945 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00638069 |
| TFF1 | trefoil factor 1 | -0.00634097 |
| TPBG | trophoblast glycoprotein | -0.00631339 |
| DIPK1A | divergent protein kinase domain 1A | -0.00628138 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0062514 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00625129 |
| S100A8 | S100 calcium binding protein A8 | -0.00624239 |
| RCAN1 | regulator of calcineurin 1 | -0.00619259 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00618554 |
| TFRC | transferrin receptor | -0.00616618 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00615989 |
| CLDN10 | claudin 10 | -0.00611341 |
| LAMB1 | laminin, beta 1 | -0.00610185 |
| CTSD | cathepsin D | -0.00609327 |
| ATF3 | activating transcription factor 3 | -0.00608286 |
| CLDN7 | claudin 7 | -0.00606531 |
| HMGA1 | high mobility group AT-hook 1 | -0.00601871 |
| LEFTY1 | left-right determination factor 1 | -0.00601309 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.0059944 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0059943 |
| BLNK | B-cell linker | -0.00598965 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00598855 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00598648 |
| TPM4 | tropomyosin 4 | -0.00598277 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00597474 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00590993 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00588851 |
| KYNU | kynureninase | -0.00587615 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00586412 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | -0.00586296 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00583635 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | -0.0058351 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00582606 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00582293 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00579505 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00575279 |
| PCDH9 | protocadherin 9 | -0.00573192 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00572877 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00565922 |
| MMP7 | matrix metallopeptidase 7 | -0.00565849 |
| SRGN | serglycin | -0.00565275 |
| MUC16 | mucin 16, cell surface associated | -0.00562506 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.00560848 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.00556258 |
| CLTB | clathrin, light chain B | -0.00556165 |
| MT1F | metallothionein 1F | -0.00554362 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00553557 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00552498 |
| DAXX | death-domain associated protein | -0.00551568 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.00549637 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00547251 |
| SP100 | SP100 nuclear antigen | -0.00546277 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00545255 |
| GRIA1 | glutamate receptor, ionotropic, AMPA 1 | -0.0054353 |
| MAL | mal, T-cell differentiation protein | -0.00540977 |
| INHBA | inhibin, beta A | -0.00539413 |
| HIRA | histone cell cycle regulator | -0.0053611 |
| MRC2 | mannose receptor, C type 2 | -0.00535091 |
| KIAA0226L | KIAA0226-like | -0.00534823 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00532515 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0053219 |
| WT1 | Wilms tumor 1 | -0.0053011 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00528775 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00523098 |
| LXN | latexin | -0.00521828 |
| KRT7 | keratin 7, type II | -0.00521442 |
| HMOX1 | heme oxygenase 1 | -0.00521319 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.00521008 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.00519246 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00514214 |
| MX1 | MX dynamin-like GTPase 1 | -0.00514127 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.005133 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00512178 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | -0.00512026 |
| PLAT | plasminogen activator, tissue | -0.005079 |
| PLIN3 | perilipin 3 | -0.00507276 |
| UMOD | uromodulin | -0.00506534 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.00505972 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.00505674 |
| TP53BP1 | tumor protein p53 binding protein 1 | -0.00504891 |
| LASP1 | LIM and SH3 protein 1 | -0.00504604 |
| GPR137B | G protein-coupled receptor 137B | -0.00503565 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00502505 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00502174 |
| REEP5 | receptor accessory protein 5 | -0.00502145 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00501748 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.0050144 |
| PROM1 | prominin 1 | -0.00500559 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.00500176 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.004987 |
| OPTN | optineurin | -0.00497066 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 | -0.00496003 |
| IL2RG | interleukin 2 receptor, gamma | -0.00495117 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.00490448 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00489404 |
| CFDP1 | craniofacial development protein 1 | -0.00486868 |
| ZW10 | zw10 kinetochore protein | -0.00486147 |
| SGCE | sarcoglycan, epsilon | -0.00485541 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00484951 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00484819 |
| AZIN1 | antizyme inhibitor 1 | -0.00483327 |
| MGLL | monoglyceride lipase | -0.00482789 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | -0.00482139 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00482012 |
| ABHD5 | abhydrolase domain containing 5 | -0.00481389 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.0048034 |
| OPN3 | opsin 3 | -0.00477376 |
| GALC | galactosylceramidase | -0.00476601 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) | -0.00474998 |
| IER3 | immediate early response 3 | -0.0047479 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00474312 |
| GDI2 | GDP dissociation inhibitor 2 | -0.00473109 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.00473084 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.0047265 |
| DENND2D | DENN/MADD domain containing 2D | -0.00469447 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00469062 |
| EPYC | epiphycan | -0.00467199 |
| EHF | ets homologous factor | -0.00467094 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -0.00465792 |
| UBFD1 | ubiquitin family domain containing 1 | -0.00465272 |
| OGA | O-GlcNAcase | -0.00463846 |
| IL17RB | interleukin 17 receptor B | -0.00462292 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00461831 |
| CLMN | calmin (calponin-like, transmembrane) | -0.00461708 |
| TEX10 | testis expressed 10 | -0.00460878 |
| MAPK13 | mitogen-activated protein kinase 13 | -0.00460795 |
| MVP | major vault protein | -0.00459521 |
| HOMER1 | homer scaffolding protein 1 | -0.00459158 |
| EHD1 | EH-domain containing 1 | -0.00458347 |
| TRAF4 | TNF receptor-associated factor 4 | -0.00457619 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00455896 |
| ECM1 | extracellular matrix protein 1 | -0.00455785 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00454999 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00454588 |
| PGAP3 | post-GPI attachment to proteins 3 | -0.00453911 |
| BID | BH3 interacting domain death agonist | -0.00451439 |
| KIAA0355 | KIAA0355 | -0.00451329 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | -0.00450571 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00450457 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.00450295 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00449218 |
| AVEN | apoptosis, caspase activation inhibitor | -0.0044907 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.00449069 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00448999 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | -0.00448451 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00448251 |
| XIC | X chromosome inactivation center | -0.00446552 |
| CFI | complement factor I | -0.00446499 |
| IER5 | immediate early response 5 | -0.004464 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00446385 |
| AKIRIN1 | akirin 1 | -0.00445244 |
| PRKCA | protein kinase C, alpha | -0.00445211 |
| ANXA11 | annexin A11 | -0.00444945 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | -0.00444052 |
| PRKD1 | protein kinase D1 | -0.00443988 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.00440847 |
| CALB1 | calbindin 1, 28kDa | -0.00439808 |
| SDC1 | syndecan 1 | -0.00439508 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.00439273 |
| SORD | sorbitol dehydrogenase | -0.00438417 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00438048 |
| METTL7A | methyltransferase like 7A | -0.00438015 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00437665 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.0043749 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00436932 |
| INAVA | innate immunity activator | -0.00436889 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00436002 |
| OLFML3 | olfactomedin-like 3 | -0.00434954 |
| PF4 | platelet factor 4 | -0.00434576 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0043333 |
| SLC22A18 | solute carrier family 22, member 18 | -0.00432572 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00432092 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00431524 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00431421 |
| TUFT1 | tuftelin 1 | -0.00430906 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -0.00430879 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.0042964 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00429583 |
| SELENBP1 | selenium binding protein 1 | -0.0042957 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00429459 |
| PRKCQ | protein kinase C, theta | -0.00429449 |
| PTPRO | protein tyrosine phosphatase, receptor type, O | -0.00427964 |
| CBFB | core-binding factor, beta subunit | -0.00427784 |
