CD63 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description CD63 molecule|The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012] (NCBI Entrez Gene Database, 967)
External Link http://www.ncbi.nlm.nih.gov/gene/967
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Genes

228 interacting proteins for CD63 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACTN4 actinin, alpha 4
ADAM10 ADAM metallopeptidase domain 10
ADD1 adducin 1 (alpha)
ADGRL4 adhesion G protein-coupled receptor L4
AGR2 anterior gradient 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA1 annexin A1
ANXA2 annexin A2
ANXA6 annexin A6
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
BANF1 barrier to autointegration factor 1
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
BSG basigin (Ok blood group)
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAND1 cullin-associated and neddylation-dissociated 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CD19 CD19 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CD47 CD47 molecule
CD59 CD59 molecule, complement regulatory protein
CD81 CD81 molecule
CD82 CD82 molecule
CD9 CD9 molecule
CDC42 cell division cycle 42
CDCP1 CUB domain containing protein 1
CHMP1A charged multivesicular body protein 1A
CHMP1B charged multivesicular body protein 1B
CHMP2B charged multivesicular body protein 2B
CHMP3 charged multivesicular body protein 3
CHMP4B charged multivesicular body protein 4B
CHMP5 charged multivesicular body protein 5
CLDND1 claudin domain containing 1
CLTA clathrin, light chain A
CLTC clathrin, heavy chain (Hc)
COBLL1 cordon-bleu WH2 repeat protein-like 1
CST4 cystatin S
CSTA cystatin A (stefin A)
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTSD cathepsin D
DAAM1 dishevelled associated activator of morphogenesis 1
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DNM2 dynamin 2
DSTN destrin (actin depolymerizing factor)
DTYMK deoxythymidylate kinase (thymidylate kinase)
EHD1 EH-domain containing 1
EIF3M eukaryotic translation initiation factor 3, subunit M
EMP1 epithelial membrane protein 1
EMP3 epithelial membrane protein 3
ENO1 enolase 1, (alpha)
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPCAM epithelial cell adhesion molecule
EZR ezrin
FAP fibroblast activation protein, alpha
FCHO2 FCH domain only 2
FLNA filamin A, alpha
FLNB filamin B, beta
FLNC filamin C, gamma
FLOT1 flotillin 1
FTH1 ferritin, heavy polypeptide 1
GALK1 galactokinase 1
GBA glucosidase, beta, acid
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GLMP glycosylated lysosomal membrane protein
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GPA33 glycoprotein A33 (transmembrane)
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HLA-A major histocompatibility complex, class I, A
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
ICAM2 intercellular adhesion molecule 2
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGLL1 immunoglobulin lambda-like polypeptide 1
IGSF8 immunoglobulin superfamily, member 8
IL13RA2 interleukin 13 receptor, alpha 2
ILF3 interleukin enhancer binding factor 3, 90kDa
IQGAP1 IQ motif containing GTPase activating protein 1
IST1 increased sodium tolerance 1 homolog (yeast)
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA6 integrin, alpha 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB4 integrin, beta 4
ITGB5 integrin, beta 5
IWS1 IWS1 homolog (S. cerevisiae)
KIAA1033 KIAA1033
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LNPEP leucyl/cystinyl aminopeptidase
LPCAT2 lysophosphatidylcholine acyltransferase 2
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MCAM melanoma cell adhesion molecule
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MITD1 MIT, microtubule interacting and transport, domain containing 1
MME membrane metallo-endopeptidase
MOGS mannosyl-oligosaccharide glucosidase
MPZL1 myelin protein zero-like 1
MPZL2 myelin protein zero-like 2
MSN moesin
MUC13 mucin 13, cell surface associated
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
MYO1A myosin IA
MYO1B myosin IB
MYO1D myosin ID
MYO3B myosin IIIB
MYOF myoferlin
NCSTN nicastrin
NPC1 Niemann-Pick disease, type C1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPTN neuroplastin
PDCD10 programmed cell death 10
PDIA6 protein disulfide isomerase family A, member 6
PHACTR4 phosphatase and actin regulator 4
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PIP prolactin-induced protein
PITPNB phosphatidylinositol transfer protein, beta
PKP4 plakophilin 4
PLBD1 phospholipase B domain containing 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEC plectin
PPAP2C phosphatidic acid phosphatase type 2C
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRNP prion protein
PTGES2 prostaglandin E synthase 2
PTGFRN prostaglandin F2 receptor inhibitor
PTPRJ protein tyrosine phosphatase, receptor type, J
PTTG1IP pituitary tumor-transforming 1 interacting protein
RAB12 RAB12, member RAS oncogene family
RAB14 RAB14, member RAS oncogene family
RAB15 RAB15, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAB22A RAB22A, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RALB v-ral simian leukemia viral oncogene homolog B
RDX radixin
RHOB ras homolog family member B
RNF13 ring finger protein 13
RRAS related RAS viral (r-ras) oncogene homolog
RSU1 Ras suppressor protein 1
S100A11 S100 calcium binding protein A11
SCARB2 scavenger receptor class B, member 2
SDCBP syndecan binding protein (syntenin)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC35F6 solute carrier family 35, member F6
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC43A3 solute carrier family 43, member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SPPL2A signal peptide peptidase like 2A
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
STOM stomatin
STX8 syntaxin 8
SYNGR2 synaptogyrin 2
SYPL1 synaptophysin-like 1
TACSTD2 tumor-associated calcium signal transducer 2
TFRC transferrin receptor
TIMP1 TIMP metallopeptidase inhibitor 1
TM9SF1 transmembrane 9 superfamily member 1
TMEM181 transmembrane protein 181
TMEM192 transmembrane protein 192
TMEM206 transmembrane protein 206
TMEM87A transmembrane protein 87A
TMOD3 tropomodulin 3 (ubiquitous)
TOMM34 translocase of outer mitochondrial membrane 34
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TSC1 tuberous sclerosis 1
TSPAN14 tetraspanin 14
TSPAN3 tetraspanin 3
TSPAN9 tetraspanin 9
UBC ubiquitin C
UBQLN2 ubiquilin 2
VAMP7 vesicle-associated membrane protein 7
VAMP8 vesicle-associated membrane protein 8
VKORC1 vitamin K epoxide reductase complex, subunit 1
VTI1B vesicle transport through interaction with t-SNAREs 1B