| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | CD74 molecule, major histocompatibility complex, class II invariant chain|The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 972) |
| External Link | https://ncbi.nlm.nih.gov/gene/972 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the CD74 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| THBS1 | thrombospondin 1 | 0.0243361 |
| HTRA1 | HtrA serine peptidase 1 | 0.0184887 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0183589 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0179908 |
| COG7 | component of oligomeric golgi complex 7 | 0.0164664 |
| RGS4 | regulator of G-protein signaling 4 | 0.0160042 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0151018 |
| KRT23 | keratin 23, type I | 0.0147873 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0145441 |
| GPX1 | glutathione peroxidase 1 | 0.0143695 |
| WASHC4 | WASH complex subunit 4 | 0.0140787 |
| PTK2B | protein tyrosine kinase 2 beta | 0.0140733 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.0139476 |
| THBS2 | thrombospondin 2 | 0.013463 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.013192 |
| RPS27L | ribosomal protein S27-like | 0.0127495 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.0127457 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0125934 |
| SFRP4 | secreted frizzled-related protein 4 | 0.012059 |
| EVI2A | ecotropic viral integration site 2A | 0.0120042 |
| S100A8 | S100 calcium binding protein A8 | 0.0116932 |
| LRRC17 | leucine rich repeat containing 17 | 0.0114718 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0113534 |
| PITX3 | paired-like homeodomain 3 | 0.0111766 |
| ZNF91 | zinc finger protein 91 | 0.0110645 |
| ADIRF | adipogenesis regulatory factor | 0.0109934 |
| SRGN | serglycin | 0.0109393 |
| RGS1 | regulator of G-protein signaling 1 | 0.0109302 |
| LCN2 | lipocalin 2 | 0.0108486 |
| BCL2A1 | BCL2-related protein A1 | 0.0107226 |
| MT1E | metallothionein 1E | 0.0106851 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0106144 |
| PDGFC | platelet derived growth factor C | 0.0104966 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0104306 |
| COL10A1 | collagen, type X, alpha 1 | 0.01042 |
| IPO13 | importin 13 | 0.0104088 |
| PLK2 | polo-like kinase 2 | 0.0103971 |
| FN1 | fibronectin 1 | 0.0103739 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0103503 |
| LST1 | leukocyte specific transcript 1 | 0.0103304 |
| NOTCH1 | notch 1 | 0.0101329 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.0101292 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0100974 |
| LXN | latexin | 0.0098625 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00986166 |
| S100A9 | S100 calcium binding protein A9 | 0.0098063 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00979781 |
| NOTCH2NL | notch 2 N-terminal like | 0.00965326 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00961999 |
| CNN3 | calponin 3, acidic | 0.00960875 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00955896 |
| SNAI2 | snail family zinc finger 2 | 0.00955434 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00953963 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00949823 |
| CFB | complement factor B | 0.00940029 |
| HBD | hemoglobin, delta | 0.00933443 |
| FST | follistatin | 0.00928437 |
| CLC | Charcot-Leyden crystal galectin | 0.00927286 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00926593 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00926244 |
| CTSK | cathepsin K | 0.0092248 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00922004 |
| ASPN | asporin | 0.00919716 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00910997 |
| BBX | bobby sox homolog (Drosophila) | 0.00910096 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00903962 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00903158 |
| ARG1 | arginase 1 | 0.00890369 |
| ANXA1 | annexin A1 | 0.00889969 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0088223 |
| LRRC15 | leucine rich repeat containing 15 | 0.00880829 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00877478 |
| RAP2A | RAP2A, member of RAS oncogene family | 0.00877018 |
| PEG10 | paternally expressed 10 | 0.00876641 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.00870363 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.00868733 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00868555 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00866547 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00863132 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00863116 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.00854566 |
| PYCARD | PYD and CARD domain containing | 0.00850196 |
| ZNF264 | zinc finger protein 264 | 0.0084752 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00844306 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00843363 |
| GPR137B | G protein-coupled receptor 137B | 0.00833672 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.00832281 |
| NMRK1 | nicotinamide riboside kinase 1 | 0.00821345 |
| MSMB | microseminoprotein, beta- | 0.0081858 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00815805 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00813336 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00808111 |
| CD9 | CD9 molecule | 0.00801944 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00801233 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00800469 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00799976 |
| SGCE | sarcoglycan, epsilon | 0.00799083 |
| KLF2 | Kruppel-like factor 2 | 0.0079731 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00796605 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 0.00795728 |
| LOXL2 | lysyl oxidase-like 2 | 0.00795124 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00792719 |
| ECM1 | extracellular matrix protein 1 | 0.00789348 |
| GSDME | gasdermin E | 0.00787735 |
| PAK1IP1 | PAK1 interacting protein 1 | 0.00785236 |
| DOK5 | docking protein 5 | 0.00783785 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | 0.00783497 |
| OPTN | optineurin | 0.00781861 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00781817 |
| BPI | bactericidal/permeability-increasing protein | 0.00780923 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00777402 |
| PXDN | peroxidasin | 0.00774529 |
| LY96 | lymphocyte antigen 96 | 0.00774011 |
| SUCO | SUN domain containing ossification factor | 0.00771487 |
| LYPLA1 | lysophospholipase I | 0.00771321 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.00769695 |
| EREG | epiregulin | 0.00767298 |
| REXO2 | RNA exonuclease 2 | 0.00764391 |
| TEX30 | testis expressed 30 | 0.00763843 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.00763544 |
| STK10 | serine/threonine kinase 10 | 0.00760395 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00756422 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.00755908 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00754958 |
| DSG2 | desmoglein 2 | 0.00752966 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00748629 |
| CD52 | CD52 molecule | 0.00747556 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00747104 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.00745979 |
| EAF2 | ELL associated factor 2 | 0.00744993 |
| OAT | ornithine aminotransferase | 0.00743751 |
| CTSD | cathepsin D | 0.00743517 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00743404 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | 0.00742511 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00741935 |
| RPL26L1 | ribosomal protein L26-like 1 | 0.00736613 |
| STK26 | serine/threonine protein kinase 26 | 0.00735506 |
| NAV3 | neuron navigator 3 | 0.00734903 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00734605 |
| CDK14 | cyclin-dependent kinase 14 | 0.00733301 |
| KLK5 | kallikrein-related peptidase 5 | 0.00733115 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00724175 |
| PCTP | phosphatidylcholine transfer protein | 0.00721216 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00720158 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.0072009 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00718056 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.00717941 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00717735 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00715756 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00715721 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00713635 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00712375 |
| KRT5 | keratin 5, type II | 0.00711517 |
| NOX4 | NADPH oxidase 4 | 0.00707781 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.00707089 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00706611 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.00706349 |
| ESR1 | estrogen receptor 1 | 0.00705183 |
| DIPK1A | divergent protein kinase domain 1A | 0.0070479 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00703602 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | 0.0070279 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.00702569 |
| SEC24A | SEC24 family member A | 0.00702432 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | 0.00702038 |
| ZNF652 | zinc finger protein 652 | 0.00701401 |
| CEL | carboxyl ester lipase | 0.0069891 |
| AHR | aryl hydrocarbon receptor | 0.00697465 |
| CLINT1 | clathrin interactor 1 | 0.0069686 |
| HINT1 | histidine triad nucleotide binding protein 1 | 0.00696551 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00694738 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00694121 |
| GSAP | gamma-secretase activating protein | 0.00693782 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00691017 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00690414 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | 0.00687792 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00686859 |
| DCN | decorin | 0.0068672 |
| CYBB | cytochrome b-245, beta polypeptide | 0.00686274 |
| CAMP | cathelicidin antimicrobial peptide | 0.00685754 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | 0.00681118 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 0.00677974 |
| LYRM4 | LYR motif containing 4 | 0.00676979 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00676343 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00673823 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.00673352 |
| PDCD10 | programmed cell death 10 | 0.00672726 |
| HEXB | hexosaminidase B (beta polypeptide) | 0.00671725 |
| S100A12 | S100 calcium binding protein A12 | 0.00671624 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | 0.00671366 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 0.00671002 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00670221 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00669446 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0066873 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00668379 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.00668369 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | 0.00668003 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.00666164 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00665759 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0066463 |
| PPIF | peptidylprolyl isomerase F | 0.00664145 |
| ATP5MJ | ATP synthase membrane subunit j | 0.00663534 |
| HNMT | histamine N-methyltransferase | 0.00663366 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.00663069 |
| UROD | uroporphyrinogen decarboxylase | 0.00662623 |
| ZNF160 | zinc finger protein 160 | 0.00662598 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00660912 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00658953 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00658722 |
| TSPO | translocator protein (18kDa) | 0.00657882 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00656614 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 0.00653716 |
| SMAD3 | SMAD family member 3 | 0.00653417 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.00652175 |
| IRF9 | interferon regulatory factor 9 | 0.00652109 |
| WWC1 | WW and C2 domain containing 1 | 0.00649452 |
| MIR22HG | MIR22 host gene | 0.00649449 |
| RIN2 | Ras and Rab interactor 2 | 0.00649378 |
| PLXNC1 | plexin C1 | 0.00648527 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0064725 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0064697 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | 0.00646523 |
| APOC1 | apolipoprotein C-I | 0.00645567 |
| IL1B | interleukin 1, beta | 0.0064333 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00643298 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00642258 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00641282 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.0064024 |
| ZNF721 | zinc finger protein 721 | 0.00640221 |
| MMP8 | matrix metallopeptidase 8 | 0.00639503 |
| GMPR | guanosine monophosphate reductase | 0.00639207 |
| AZU1 | azurocidin 1 | 0.00636839 |
| FLCN | folliculin | 0.00635699 |
| CTBS | chitobiase, di-N-acetyl- | 0.00635137 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00634835 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | 0.00634455 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | 0.00632611 |
| XIC | X chromosome inactivation center | 0.00631724 |
| SLC44A4 | solute carrier family 44, member 4 | 0.0063134 |
| RPA3 | replication protein A3, 14kDa | 0.00630552 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00630198 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00630131 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00629744 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00628638 |
| KLK10 | kallikrein-related peptidase 10 | 0.00627422 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 0.00626316 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00625495 |
| MAGT1 | magnesium transporter 1 | 0.00624597 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00623773 |
| NUP58 | nucleoporin 58 | 0.00623215 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAGEA3 | melanoma antigen family A3 | -0.0136195 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.0134917 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0134468 |
| MAGEA12 | melanoma antigen family A12 | -0.0131788 |
| MGP | matrix Gla protein | -0.0128856 |
| NRN1 | neuritin 1 | -0.0126246 |
| NELL2 | NEL-like 2 (chicken) | -0.0123624 |
| PRAME | preferentially expressed antigen in melanoma | -0.0120855 |
| HOXC6 | homeobox C6 | -0.0116649 |
| CD99 | CD99 molecule | -0.011621 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0113114 |
| CHGB | chromogranin B | -0.0111951 |
| CHKB | choline kinase beta | -0.0110935 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0109049 |
| TSPAN8 | tetraspanin 8 | -0.0107858 |
| MSX1 | msh homeobox 1 | -0.0107826 |
| NEFM | neurofilament, medium polypeptide | -0.0107618 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.010685 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0104835 |
| NLGN4X | neuroligin 4, X-linked | -0.0104492 |
| AGR2 | anterior gradient 2 | -0.01043 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.010377 |
| PTCH1 | patched 1 | -0.0101359 |
| RETREG1 | reticulophagy regulator 1 | -0.0100028 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00993645 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00991977 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00963363 |
| COL1A2 | collagen, type I, alpha 2 | -0.00954653 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00947892 |
| TRIM28 | tripartite motif containing 28 | -0.00947605 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -0.00947542 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00945251 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00940234 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.0093057 |
| MAOA | monoamine oxidase A | -0.00925936 |
| STC1 | stanniocalcin 1 | -0.00914614 |
| CFH | complement factor H | -0.00913598 |
| HOXB6 | homeobox B6 | -0.00909438 |
| FCGBP | Fc fragment of IgG binding protein | -0.00907525 |
| TMEM176B | transmembrane protein 176B | -0.00901967 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00900887 |
| STMN2 | stathmin 2 | -0.0089728 |
| HOXB7 | homeobox B7 | -0.0088782 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00883378 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00881811 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | -0.0088132 |
| SFTPB | surfactant protein B | -0.00879725 |
| EDN3 | endothelin 3 | -0.00869724 |
| VWF | von Willebrand factor | -0.00858792 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00857934 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00857564 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0085555 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00850005 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00846068 |
| GPC3 | glypican 3 | -0.00843809 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00841605 |
| INSR | insulin receptor | -0.0083965 |
| SYNM | synemin, intermediate filament protein | -0.00838884 |
| DES | desmin | -0.00835965 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00826786 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00825713 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.0081593 |
| MYO5C | myosin VC | -0.00812557 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.00810724 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | -0.00802321 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.00800481 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00800396 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | -0.00799865 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.00798692 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00798435 |
| CAPNS1 | calpain, small subunit 1 | -0.00795527 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00794986 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00794532 |
| OLFM1 | olfactomedin 1 | -0.00790079 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.00789377 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.00784079 |
| CHN1 | chimerin 1 | -0.00782071 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00778917 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.0077814 |
| PLK1 | polo-like kinase 1 | -0.00776164 |
| CH25H | cholesterol 25-hydroxylase | -0.00773497 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00772989 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00772628 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -0.00770214 |
| CARM1 | coactivator-associated arginine methyltransferase 1 | -0.00766449 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00766188 |
| EDNRB | endothelin receptor type B | -0.00764111 |
| GSE1 | Gse1 coiled-coil protein | -0.00762818 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.00762134 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00761871 |
| FKBP5 | FK506 binding protein 5 | -0.00761634 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | -0.00759517 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00756565 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0075632 |
| TFF1 | trefoil factor 1 | -0.00753423 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.00749933 |
| TRIP13 | thyroid hormone receptor interactor 13 | -0.00747253 |
| PRF1 | perforin 1 (pore forming protein) | -0.0074621 |
| CTSZ | cathepsin Z | -0.00741426 |
| CD14 | CD14 molecule | -0.0073622 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00734837 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00733199 |
| SI | sucrase-isomaltase (alpha-glucosidase) | -0.00729842 |
| TBCD | tubulin folding cofactor D | -0.00727567 |
| MEOX2 | mesenchyme homeobox 2 | -0.00726647 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00726386 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -0.00726141 |
| PCGF2 | polycomb group ring finger 2 | -0.00720253 |
| CDCA3 | cell division cycle associated 3 | -0.00719885 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.0071939 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00718261 |
| RBPMS | RNA binding protein with multiple splicing | -0.00717593 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00717057 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00716138 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | -0.00714685 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00713902 |
| NDC80 | NDC80 kinetochore complex component | -0.00713866 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00713185 |
| SETBP1 | SET binding protein 1 | -0.007087 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | -0.00708685 |
| RGS5 | regulator of G-protein signaling 5 | -0.00708426 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00706915 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00705877 |
| MKI67 | marker of proliferation Ki-67 | -0.00704334 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | -0.00700508 |
| RHOA | ras homolog family member A | -0.00700367 |
| FABP7 | fatty acid binding protein 7, brain | -0.00699922 |
| MMP12 | matrix metallopeptidase 12 | -0.00699323 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00696541 |
| SORD | sorbitol dehydrogenase | -0.00694873 |
| MTA1 | metastasis associated 1 | -0.00691226 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.006903 |
| MMP3 | matrix metallopeptidase 3 | -0.0068561 |
| TWF2 | twinfilin actin binding protein 2 | -0.00684021 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00683224 |
| PRKCSH | protein kinase C substrate 80K-H | -0.00681446 |
| NES | nestin | -0.00679658 |
| CD151 | CD151 molecule (Raph blood group) | -0.00675499 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00674246 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00671561 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00670899 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.00669026 |
| ASF1B | anti-silencing function 1B histone chaperone | -0.0066353 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -0.00662516 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | -0.00662422 |
| CD81 | CD81 molecule | -0.00661497 |
| ADCY3 | adenylate cyclase 3 | -0.00659851 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | -0.00658421 |
| CS | citrate synthase | -0.0065722 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.00655097 |
| SAE1 | SUMO1 activating enzyme subunit 1 | -0.00653549 |
| SELENBP1 | selenium binding protein 1 | -0.00652484 |
| LAMA4 | laminin, alpha 4 | -0.00650807 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00649137 |
| CLCA1 | chloride channel accessory 1 | -0.00649026 |
| CCDC22 | coiled-coil domain containing 22 | -0.00648663 |
| L1CAM | L1 cell adhesion molecule | -0.00648337 |
| TMEM176A | transmembrane protein 176A | -0.00647943 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00647513 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | -0.00646974 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00644538 |
| LASP1 | LIM and SH3 protein 1 | -0.0064379 |
| REG1A | regenerating islet-derived 1 alpha | -0.00642737 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -0.00640826 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00640334 |
| PDCD6 | programmed cell death 6 | -0.00640283 |
| REEP1 | receptor accessory protein 1 | -0.00639483 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.0063914 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | -0.00638194 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00637836 |
| KIF20A | kinesin family member 20A | -0.00634724 |
| CCNB1 | cyclin B1 | -0.00634655 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.00634371 |
| H2AX | H2A.X variant histone | -0.00634193 |
| TCTA | T-cell leukemia translocation altered | -0.00634175 |
| DGS2 | DiGeorge syndrome/velocardiofacial syndrome complex 2 | -0.00634065 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.00632619 |
| PRDX2 | peroxiredoxin 2 | -0.00632354 |
| IMMT | inner membrane protein, mitochondrial | -0.00632303 |
| FLNA | filamin A, alpha | -0.00631865 |
| PTBP1 | polypyrimidine tract binding protein 1 | -0.00630154 |
| CD1E | CD1e molecule | -0.00629984 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | -0.00628407 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00627739 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00627547 |
| NDRG1 | N-myc downstream regulated 1 | -0.00627377 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00627369 |
| S100B | S100 calcium binding protein B | -0.00625653 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00625548 |
| DST | dystonin | -0.00625513 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00624781 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.00623937 |
| NNT | nicotinamide nucleotide transhydrogenase | -0.00623785 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00623557 |
| GLG1 | golgi glycoprotein 1 | -0.00622913 |
| NCOR2 | nuclear receptor corepressor 2 | -0.00622883 |
| ELP1 | elongator acetyltransferase complex subunit 1 | -0.0062202 |
| SSRP1 | structure specific recognition protein 1 | -0.00621928 |
| VSNL1 | visinin-like 1 | -0.00621218 |
| FOXM1 | forkhead box M1 | -0.00621035 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00620845 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0062033 |
| SAMM50 | SAMM50 sorting and assembly machinery component | -0.00619889 |
| VWA1 | von Willebrand factor A domain containing 1 | -0.00619039 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | -0.00618796 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00618049 |
| CDC20 | cell division cycle 20 | -0.00617695 |
| EGR2 | early growth response 2 | -0.00616306 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00614853 |
| MLXIP | MLX interacting protein | -0.00612947 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -0.00611928 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.00611674 |
| TPI1 | triosephosphate isomerase 1 | -0.00611372 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00610055 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00609706 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | -0.00608351 |
| SDHAP1 | succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 | -0.0060768 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00607577 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00607222 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00606147 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.00606107 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00605581 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00605405 |
| FZD5 | frizzled class receptor 5 | -0.00604068 |
| HEPH | hephaestin | -0.00604032 |
| TMSB15A | thymosin beta 15a | -0.00603549 |
| TLE5 | TLE family member 5, transcriptional modulator | -0.00601591 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00601022 |
| A2M | alpha-2-macroglobulin | -0.00600268 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.00599917 |
| PFKL | phosphofructokinase, liver | -0.00598298 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00597086 |
| NUCB1 | nucleobindin 1 | -0.00596459 |
| BMP4 | bone morphogenetic protein 4 | -0.00596126 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00596046 |
| C9ORF3 | chromosome 9 open reading frame 3 | -0.00596019 |
| MAGEA4 | melanoma antigen family A4 | -0.00595679 |
| ACTB | actin, beta | -0.00594523 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0059422 |
| MATN2 | matrilin 2 | -0.00592902 |
| CBS | cystathionine-beta-synthase | -0.00592884 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00592754 |
| CD93 | CD93 molecule | -0.00592596 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00592413 |
| CALCA | calcitonin-related polypeptide alpha | -0.00591232 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00591199 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.00590686 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00589415 |
| CLCA2 | chloride channel accessory 2 | -0.0058884 |
