CD80 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description CD80 molecule|The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 941)
External Link https://ncbi.nlm.nih.gov/gene/941
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Genes

499 genes differentially expressed following the CD80 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HSPB1 heat shock 27kDa protein 1 0.0200827
SLPI secretory leukocyte peptidase inhibitor 0.0160713
LCN2 lipocalin 2 0.0153188
AQP3 aquaporin 3 (Gill blood group) 0.0152317
S100A9 S100 calcium binding protein A9 0.0146689
S100A8 S100 calcium binding protein A8 0.0140475
KYNU kynureninase 0.0128923
S100A7 S100 calcium binding protein A7 0.0128505
MGLL monoglyceride lipase 0.0114824
PDZK1IP1 PDZK1 interacting protein 1 0.011416
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.0111736
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0111501
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.0109982
SSBP2 single-stranded DNA binding protein 2 0.0108681
KRT13 keratin 13, type I 0.0105669
CRISP3 cysteine-rich secretory protein 3 0.0104293
COG7 component of oligomeric golgi complex 7 0.0101761
PPL periplakin 0.0101094
SPRR3 small proline-rich protein 3 0.0100287
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0100274
CFB complement factor B 0.010002
LYPD3 LY6/PLAUR domain containing 3 0.009959
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00991389
PERP PERP, TP53 apoptosis effector 0.00990025
TFPI2 tissue factor pathway inhibitor 2 0.00985234
L1CAM L1 cell adhesion molecule 0.00979449
BAX BCL2-associated X protein 0.00978451
AKR1C2 aldo-keto reductase family 1, member C2 0.0097776
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00975826
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00962715
TFRC transferrin receptor 0.00953133
SLC38A2 solute carrier family 38, member 2 0.0095286
CLDN10 claudin 10 0.00951047
TACSTD2 tumor-associated calcium signal transducer 2 0.00947437
RAB13 RAB13, member RAS oncogene family 0.0094378
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00941043
MVP major vault protein 0.00937763
OSMR oncostatin M receptor 0.00920114
MSMB microseminoprotein, beta- 0.00906864
MAP7 microtubule-associated protein 7 0.00905618
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.00893416
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.00889922
SFRP1 secreted frizzled-related protein 1 0.00886512
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00885911
KLK7 kallikrein-related peptidase 7 0.0087878
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00875777
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00868453
CRABP2 cellular retinoic acid binding protein 2 0.00863903
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.0086251
HMGA1 high mobility group AT-hook 1 0.00855702
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.00851441
MME membrane metallo-endopeptidase 0.00844355
TMEM45A transmembrane protein 45A 0.00839493
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00836783
BLNK B-cell linker 0.00826961
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00826706
NCOA3 nuclear receptor coactivator 3 0.00824155
RFTN1 raftlin, lipid raft linker 1 0.00822213
HLA-F major histocompatibility complex, class I, F 0.00821488
SLC43A3 solute carrier family 43, member 3 0.00817993
CSTA cystatin A (stefin A) 0.00810494
UPK1B uroplakin 1B 0.0080946
BID BH3 interacting domain death agonist 0.00804658
HLA-C major histocompatibility complex, class I, C 0.00801655
ZNF91 zinc finger protein 91 0.00798935
DDR2 discoidin domain receptor tyrosine kinase 2 0.00797398
LAMP3 lysosomal-associated membrane protein 3 0.00793999
RNPS1 RNA binding protein S1, serine-rich domain 0.0078896
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00788164
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00788011
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00783882
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00783672
FZD6 frizzled class receptor 6 0.0078146
H1-0 H1.0 linker histone 0.00775655
PITX1 paired-like homeodomain 1 0.00766271
IPO13 importin 13 0.00762621
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 0.00760376
NPTX2 neuronal pentraxin II 0.00760356
NTS neurotensin 0.00758298
KLK8 kallikrein-related peptidase 8 0.00757784
HOMER2 homer scaffolding protein 2 0.00754901
DEFB1 defensin, beta 1 0.00751869
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00751658
CXCL12 chemokine (C-X-C motif) ligand 12 0.00748978
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00748613
CSRP2 cysteine and glycine-rich protein 2 0.0074514
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00742049
SPRR1A small proline-rich protein 1A 0.00741531
EFNA5 ephrin-A5 0.00739244
PSCA prostate stem cell antigen 0.00737252
RHCG Rh family, C glycoprotein 0.00736108
CLCA2 chloride channel accessory 2 0.00730303
NPR1 natriuretic peptide receptor 1 0.00726319
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00725871
TMED9 transmembrane emp24 protein transport domain containing 9 0.00724283
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00719324
TGM2 transglutaminase 2 0.00718935
MMP9 matrix metallopeptidase 9 0.00715711
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00708745
CD82 CD82 molecule 0.0070772
MREG melanoregulin 0.00705755
TNIP1 TNFAIP3 interacting protein 1 0.00704341
CLTB clathrin, light chain B 0.00701048
KRT23 keratin 23, type I 0.00698042
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.0069731
ACAT2 acetyl-CoA acetyltransferase 2 0.00696457
FPGS folylpolyglutamate synthase 0.00695668
SGK1 serum/glucocorticoid regulated kinase 1 0.00695544
HECA headcase homolog (Drosophila) 0.00693634
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.00693533
SOD2 superoxide dismutase 2, mitochondrial 0.00692931
PBX3 pre-B-cell leukemia homeobox 3 0.0069264
IFI16 interferon, gamma-inducible protein 16 0.00688974
TPM4 tropomyosin 4 0.0068707
FGG fibrinogen gamma chain 0.00685045
MEIS2 Meis homeobox 2 0.00684519
OSBPL9 oxysterol binding protein-like 9 0.0068418
LXN latexin 0.00684131
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00683597
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.00681425
HLA-B major histocompatibility complex, class I, B 0.00678671
RIPK2 receptor-interacting serine-threonine kinase 2 0.00678083
TPD52L1 tumor protein D52-like 1 0.00677641
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 0.00673832
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.00672331
ACP3 acid phosphatase 3 0.00671742
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00671283
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00668311
G6PD glucose-6-phosphate dehydrogenase 0.00665934
PDZD2 PDZ domain containing 2 0.00665377
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00663192
TGFA transforming growth factor, alpha 0.00661887
EPS8L1 EPS8-like 1 0.00661792
RAB3B RAB3B, member RAS oncogene family 0.00659941
RND3 Rho family GTPase 3 0.00659102
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00654018
CSK c-src tyrosine kinase 0.00652346
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00651724
ATF3 activating transcription factor 3 0.00651249
SCGB2A1 secretoglobin, family 2A, member 1 0.0064199
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.0064185
FMO3 flavin containing monooxygenase 3 0.00641401
OLFML2A olfactomedin-like 2A 0.00634462
CXADR coxsackie virus and adenovirus receptor 0.00632866
CA12 carbonic anhydrase XII 0.00632716
MAL mal, T-cell differentiation protein 0.00631983
IL1R1 interleukin 1 receptor, type I 0.00631023
ZYX zyxin 0.0063069
VLDLR very low density lipoprotein receptor 0.0063038
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00629916
ITPRID2 ITPR interacting domain containing 2 0.00626932
EMX2 empty spiracles homeobox 2 0.00626371
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00625781
YBX3 Y box binding protein 3 0.00625765
GPNMB glycoprotein (transmembrane) nmb 0.00625132
KRT6A keratin 6A, type II 0.00624424
DSE dermatan sulfate epimerase 0.0062339
AKR1C1 aldo-keto reductase family 1, member C1 0.00622456
PPP4C protein phosphatase 4, catalytic subunit 0.00621008
VNN1 vanin 1 0.00620154
PLIN3 perilipin 3 0.00619011
IFITM3 interferon induced transmembrane protein 3 0.00616795
ACP2 acid phosphatase 2, lysosomal 0.00615884
MCM2 minichromosome maintenance complex component 2 0.00613975
JAK1 Janus kinase 1 0.00613734
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.00613021
EMP2 epithelial membrane protein 2 0.00612506
SPRR1B small proline-rich protein 1B 0.00612494
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.00609741
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.00609349
ECM1 extracellular matrix protein 1 0.00608234
RIPK4 receptor-interacting serine-threonine kinase 4 0.00608225
ALDOA aldolase A, fructose-bisphosphate 0.00607956
PELI1 pellino E3 ubiquitin protein ligase 1 0.00607279
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00606881
RTN4 reticulon 4 0.00602963
ALCAM activated leukocyte cell adhesion molecule 0.00601211
FADS1 fatty acid desaturase 1 0.00599853
MSMO1 methylsterol monooxygenase 1 0.00599195
NEU1 sialidase 1 (lysosomal sialidase) 0.00598808
CLCA4 chloride channel accessory 4 0.00596949
WNT5A wingless-type MMTV integration site family, member 5A 0.00596836
DUOX1 dual oxidase 1 0.00593625
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00591809
TWF2 twinfilin actin binding protein 2 0.00591129
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00590888
PLEK pleckstrin 0.00590733
HIGD2A HIG1 hypoxia inducible domain family, member 2A 0.00590276
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00587654
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00585233
GPX3 glutathione peroxidase 3 0.00584836
CBS cystathionine-beta-synthase 0.00578935
DUSP1 dual specificity phosphatase 1 0.00577893
MSRB1 methionine sulfoxide reductase B1 0.00577383
CTSD cathepsin D 0.005762
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0057583
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00575201
NPAS2 neuronal PAS domain protein 2 0.00574823
FXYD2 FXYD domain containing ion transport regulator 2 0.00574176
SASH1 SAM and SH3 domain containing 1 0.00574094
SPINT1 serine peptidase inhibitor, Kunitz type 1 0.00573907
SST somatostatin 0.00572343
ADGRG6 adhesion G protein-coupled receptor G6 0.00571351
GAL galanin/GMAP prepropeptide 0.00569831
DRAM1 DNA-damage regulated autophagy modulator 1 0.00569165
JUP junction plakoglobin 0.00569114
BRD4 bromodomain containing 4 0.00566296
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00565267
NT5DC2 5'-nucleotidase domain containing 2 0.00563097
GYPC glycophorin C (Gerbich blood group) 0.00561682
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00561397
FAIM Fas apoptotic inhibitory molecule 0.0056082
CP ceruloplasmin (ferroxidase) 0.0056041
CPE carboxypeptidase E 0.00559108
TRIP6 thyroid hormone receptor interactor 6 0.00557809
PEA15 phosphoprotein enriched in astrocytes 15 0.00557737
BASP1 brain abundant, membrane attached signal protein 1 0.00557611
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.00557246
SNX13 sorting nexin 13 0.00557027
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 0.00556741
BMERB1 bMERB domain containing 1 0.00556713
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00556413
UMOD uromodulin 0.00556337
MEIS1 Meis homeobox 1 0.00555364
SDC2 syndecan 2 0.00554913
QPRT quinolinate phosphoribosyltransferase 0.00554154
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.00553727
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00552756
WFDC2 WAP four-disulfide core domain 2 0.00551852
INA internexin neuronal intermediate filament protein, alpha 0.00551308
ERBB3 erb-b2 receptor tyrosine kinase 3 0.00551166
KLK10 kallikrein-related peptidase 10 0.0055094
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.00548676
HIP1 huntingtin interacting protein 1 0.00548648
BTF3P11 basic transcription factor 3 pseudogene 11 0.00548637
IFRD2 interferon-related developmental regulator 2 0.00548161
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00547696
RNF167 ring finger protein 167 0.00547508
CA2 carbonic anhydrase II 0.00547253
RSL1D1 ribosomal L1 domain containing 1 0.00546986
PTGES prostaglandin E synthase 0.0054672
BLVRB biliverdin reductase B 0.00546136
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.0054612
TAGLN2 transgelin 2 0.00545323
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00544359
HLA-E major histocompatibility complex, class I, E 0.00544137
PLXNB2 plexin B2 0.00543463
MECOM MDS1 and EVI1 complex locus 0.00540371
EIF6 eukaryotic translation initiation factor 6 0.00538684
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00537479

decreased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.0184506
EGR2 early growth response 2 -0.014743
CD320 CD320 molecule -0.0146225
TFF3 trefoil factor 3 (intestinal) -0.0140085
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.0123118
MXRA7 matrix-remodelling associated 7 -0.0122445
IFI6 interferon, alpha-inducible protein 6 -0.0120937
SCRG1 stimulator of chondrogenesis 1 -0.0115939
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0112839
HEPH hephaestin -0.0110944
IL17RB interleukin 17 receptor B -0.0107772
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -0.0107563
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0106081
CCNB1 cyclin B1 -0.0104507
COMP cartilage oligomeric matrix protein -0.010045
COL5A2 collagen, type V, alpha 2 -0.00992667
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00991107
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00989297
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00986428
TXLNA taxilin alpha -0.00973918
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00962045
SOX9 SRY (sex determining region Y)-box 9 -0.00949467
IL13RA2 interleukin 13 receptor, alpha 2 -0.00926074
GFAP glial fibrillary acidic protein -0.00923905
MYBPC1 myosin binding protein C, slow type -0.00922847
ECI2 enoyl-CoA delta isomerase 2 -0.00915272
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00902165
POSTN periostin, osteoblast specific factor -0.00881742
HMGB3 high mobility group box 3 -0.00873679
GOLM1 golgi membrane protein 1 -0.00864911
CTSK cathepsin K -0.00863164
ZBTB18 zinc finger and BTB domain containing 18 -0.00859183
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00826713
FERMT1 fermitin family member 1 -0.00823358
ALOX5 arachidonate 5-lipoxygenase -0.0082179
GATA6 GATA binding protein 6 -0.00819792
EFHD1 EF-hand domain family, member D1 -0.00810459
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00798484
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00791494
SCGB2A2 secretoglobin, family 2A, member 2 -0.00789629
SFRP4 secreted frizzled-related protein 4 -0.00782556
ITM2A integral membrane protein 2A -0.00782553
ADIRF adipogenesis regulatory factor -0.00781637
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -0.00775383
TSPAN7 tetraspanin 7 -0.00774633
APOD apolipoprotein D -0.00773013
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00772424
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.0077156
UGT8 UDP glycosyltransferase 8 -0.00770561
TPSAB1 tryptase alpha/beta 1 -0.00769135
SYNM synemin, intermediate filament protein -0.00767408
PENK proenkephalin -0.00765139
DLK1 delta-like 1 homolog (Drosophila) -0.00759053
CLCA1 chloride channel accessory 1 -0.00758962
TSPAN8 tetraspanin 8 -0.00754777
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00749841
FBLN1 fibulin 1 -0.00749722
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00741782
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00736984
MSX1 msh homeobox 1 -0.00736132
TMEM106C transmembrane protein 106C -0.00736029
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -0.00730409
MTMR11 myotubularin related protein 11 -0.00729087
TMEM176B transmembrane protein 176B -0.00728488
TBX3 T-box 3 -0.00726386
CH25H cholesterol 25-hydroxylase -0.00719775
CCL4 chemokine (C-C motif) ligand 4 -0.00719639
KRT20 keratin 20, type I -0.00718296
BGN biglycan -0.00717188
S100B S100 calcium binding protein B -0.0071662
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.00711604
MXRA5 matrix-remodelling associated 5 -0.00710556
RPS5 ribosomal protein S5 -0.00709517
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.00708035
DPY19L1 dpy-19-like 1 (C. elegans) -0.00706971
PLAAT3 phospholipase A and acyltransferase 3 -0.00704728
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00704189
SDHAF3 succinate dehydrogenase complex assembly factor 3 -0.00704004
NAP1L3 nucleosome assembly protein 1-like 3 -0.00702205
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00697253
BAG2 BCL2-associated athanogene 2 -0.0069635
EGR3 early growth response 3 -0.00694467
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00690978
TUBB2B tubulin, beta 2B class IIb -0.00690323
TKTL1 transketolase-like 1 -0.00690038
OLFM4 olfactomedin 4 -0.00689718
SDC3 syndecan 3 -0.00682123
PNMA2 paraneoplastic Ma antigen 2 -0.00681103
ACAA2 acetyl-CoA acyltransferase 2 -0.00680752
MERTK MER proto-oncogene, tyrosine kinase -0.00678285
CHKB choline kinase beta -0.00677743
EFNB2 ephrin-B2 -0.0067683
GPX2 glutathione peroxidase 2 -0.00675838
TYMS thymidylate synthetase -0.00674803
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00671381
NRN1 neuritin 1 -0.00669702
FXYD6 FXYD domain containing ion transport regulator 6 -0.00669522
AOC1 amine oxidase, copper containing 1 -0.00668717
ARL4A ADP-ribosylation factor-like 4A -0.00667733
BMP4 bone morphogenetic protein 4 -0.0066722
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.00667101
MARCKSL1 MARCKS-like 1 -0.00666682
IGFBP6 insulin-like growth factor binding protein 6 -0.00665299
RCAN1 regulator of calcineurin 1 -0.00664445
PTN pleiotrophin -0.006632
AQP4 aquaporin 4 -0.0065827
AGR2 anterior gradient 2 -0.00658005
PTCH1 patched 1 -0.00657177
GLA galactosidase, alpha -0.00655818
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00654234
SRPX sushi-repeat containing protein, X-linked -0.00654225
SIRT3 sirtuin 3 -0.00651292
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00648079
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -0.00646562
EPCAM epithelial cell adhesion molecule -0.00645972
VCAM1 vascular cell adhesion molecule 1 -0.00645078
RALB v-ral simian leukemia viral oncogene homolog B -0.00644974
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00643948
COL14A1 collagen, type XIV, alpha 1 -0.0064249
FBXO11 F-box protein 11 -0.00642234
CST3 cystatin C -0.00641582
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.0064072
PLS3 plastin 3 -0.00639202
S100A10 S100 calcium binding protein A10 -0.00638395
IQGAP2 IQ motif containing GTPase activating protein 2 -0.00635502
DIO2 deiodinase, iodothyronine, type II -0.00633145
PAGE4 P antigen family, member 4 (prostate associated) -0.00631627
AOAH acyloxyacyl hydrolase (neutrophil) -0.00629902
SCG5 secretogranin V -0.00629
CYTL1 cytokine-like 1 -0.00628996
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00628848
C1QTNF3 C1q and tumor necrosis factor related protein 3 -0.00626642
JAM3 junctional adhesion molecule 3 -0.00625246
FMOD fibromodulin -0.00623559
FAM169A family with sequence similarity 169, member A -0.00623144
COL2A1 collagen, type II, alpha 1 -0.00622051
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.006216
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00621228
FBN2 fibrillin 2 -0.00620045
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00619605
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00619544
GNLY granulysin -0.0061935
AKAP7 A kinase (PRKA) anchor protein 7 -0.00618508
OGN osteoglycin -0.006183
CRY1 cryptochrome circadian clock 1 -0.00615244
IL11RA interleukin 11 receptor, alpha -0.00611462
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00610639
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00608358
FABP1 fatty acid binding protein 1, liver -0.0060704
IFI44L interferon-induced protein 44-like -0.00606292
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00606225
GOLGA8H golgin A8 family, member H -0.00605127
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00605096
ASPN asporin -0.00604722
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00603893
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00602075
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -0.00601363
RACGAP1 Rac GTPase activating protein 1 -0.00598333
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00598164
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -0.00596367
CHPT1 choline phosphotransferase 1 -0.00596345
NUTF2 nuclear transport factor 2 -0.00595815
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00595601
PLAT plasminogen activator, tissue -0.00589613
AEBP1 AE binding protein 1 -0.00589389
TIPRL TOR signaling pathway regulator -0.0058899
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.00587709
FRZB frizzled-related protein -0.0058723
ZBTB20 zinc finger and BTB domain containing 20 -0.00586895
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00585491
CDKN2A cyclin-dependent kinase inhibitor 2A -0.00585422
LAMP5 lysosomal-associated membrane protein family, member 5 -0.005853
PDGFD platelet derived growth factor D -0.00584782
NDP Norrie disease (pseudoglioma) -0.00584632
AREG amphiregulin -0.00583059
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -0.00582951
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00582847
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00582277
TARDBP TAR DNA binding protein -0.0058179
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -0.00581448
ANXA5 annexin A5 -0.00581064
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.0058013
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00579716
GSTA4 glutathione S-transferase alpha 4 -0.00579214
CNTNAP2 contactin associated protein-like 2 -0.00576503
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00576483
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00573687
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00571224
ANKRD10 ankyrin repeat domain 10 -0.0057095
DCLK1 doublecortin-like kinase 1 -0.00570846
NXT2 nuclear transport factor 2-like export factor 2 -0.00570722
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00568781
CD69 CD69 molecule -0.00568767
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -0.00568448
PRDX4 peroxiredoxin 4 -0.00567719
ZCCHC10 zinc finger, CCHC domain containing 10 -0.005651
TYROBP TYRO protein tyrosine kinase binding protein -0.00563017
LRRC59 leucine rich repeat containing 59 -0.005618
RIN2 Ras and Rab interactor 2 -0.00561791
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.00560335
GOLGA8A golgin A8 family, member A -0.00559381
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00558687
CDKN3 cyclin-dependent kinase inhibitor 3 -0.00558626
SYNRG synergin, gamma -0.00558029
PRF1 perforin 1 (pore forming protein) -0.00557746
RBBP4 retinoblastoma binding protein 4 -0.00557223
CDO1 cysteine dioxygenase type 1 -0.00556417
PRDX2 peroxiredoxin 2 -0.00556013
CAPN6 calpain 6 -0.00555872
JCHAIN joining chain of multimeric IgA and IgM -0.00555717
COL11A1 collagen, type XI, alpha 1 -0.00554865
MAOB monoamine oxidase B -0.00554269
VSIG4 V-set and immunoglobulin domain containing 4 -0.00552783
CCNA2 cyclin A2 -0.00552508
NUSAP1 nucleolar and spindle associated protein 1 -0.0055137
ADGRL3 adhesion G protein-coupled receptor L3 -0.00550228
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -0.00549623
C1QA complement component 1, q subcomponent, A chain -0.0054956
WT1 Wilms tumor 1 -0.00549333
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -0.00549289
HBEGF heparin-binding EGF-like growth factor -0.00547806
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00547687
APOLD1 apolipoprotein L domain containing 1 -0.00546587
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00542883
PTH2R parathyroid hormone 2 receptor -0.00542877
CBX1 chromobox homolog 1 -0.00542506
TGFB3 transforming growth factor, beta 3 -0.00542427
ADAM22 ADAM metallopeptidase domain 22 -0.00542337
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.00541447
C1QB complement component 1, q subcomponent, B chain -0.00541392
PTGDS prostaglandin D2 synthase 21kDa (brain) -0.00538434
PTPRD protein tyrosine phosphatase, receptor type, D -0.00538032
SYT11 synaptotagmin XI -0.00536247
MGST3 microsomal glutathione S-transferase 3 -0.00535807
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00535144
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.0053252
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00532231
LY86 lymphocyte antigen 86 -0.00531842
CLDND1 claudin domain containing 1 -0.00531728
CLEC2D C-type lectin domain family 2, member D -0.00531695
GJA1 gap junction protein, alpha 1, 43kDa -0.00530837
JAG1 jagged 1 -0.00530525
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -0.00530253
CPA3 carboxypeptidase A3 (mast cell) -0.0052985
LIPG lipase, endothelial -0.00529311
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -0.00529229
SLCO2B1 solute carrier organic anion transporter family, member 2B1 -0.00528412
GMFB glia maturation factor, beta -0.00527489
PPT1 palmitoyl-protein thioesterase 1 -0.00525568