| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | CD81 molecule|The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] (NCBI Entrez Gene Database, 975) |
| External Link | https://ncbi.nlm.nih.gov/gene/975 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the CD81 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0137444 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.0117335 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.011603 |
| TPSAB1 | tryptase alpha/beta 1 | 0.0112861 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0106439 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0104788 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0104242 |
| RNF167 | ring finger protein 167 | 0.0101672 |
| IFI44L | interferon-induced protein 44-like | 0.0101033 |
| MSMB | microseminoprotein, beta- | 0.0099289 |
| CFB | complement factor B | 0.00965091 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00953003 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00934205 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00932821 |
| FN1 | fibronectin 1 | 0.00929131 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00914788 |
| PERP | PERP, TP53 apoptosis effector | 0.00878206 |
| AUTS2 | autism susceptibility candidate 2 | 0.00863216 |
| GPX3 | glutathione peroxidase 3 | 0.008625 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00859903 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00856823 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00842944 |
| ACP3 | acid phosphatase 3 | 0.0082991 |
| CD9 | CD9 molecule | 0.00821704 |
| EREG | epiregulin | 0.00816954 |
| RIN2 | Ras and Rab interactor 2 | 0.00815448 |
| CNN3 | calponin 3, acidic | 0.00811012 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.00795126 |
| PLK2 | polo-like kinase 2 | 0.00794626 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00786343 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00785383 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00776348 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00759694 |
| ADIRF | adipogenesis regulatory factor | 0.00758292 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00753525 |
| TARP | TCR gamma alternate reading frame protein | 0.00751107 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00750114 |
| CST7 | cystatin F (leukocystatin) | 0.00745281 |
| PMP22 | peripheral myelin protein 22 | 0.00745194 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00740253 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.0073599 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 0.00735689 |
| TGM2 | transglutaminase 2 | 0.00734098 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00733466 |
| MAP7 | microtubule-associated protein 7 | 0.00730004 |
| VEGFA | vascular endothelial growth factor A | 0.00725665 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.00713066 |
| STK26 | serine/threonine protein kinase 26 | 0.00712645 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.00712115 |
| COCH | cochlin | 0.00711942 |
| RGS1 | regulator of G-protein signaling 1 | 0.00700809 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00700588 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00697349 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00696324 |
| S100P | S100 calcium binding protein P | 0.0069144 |
| KRT14 | keratin 14, type I | 0.00689497 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.00681306 |
| EZR | ezrin | 0.0067828 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00675846 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00670935 |
| TPD52 | tumor protein D52 | 0.00663827 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00660818 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00660464 |
| YBX3 | Y box binding protein 3 | 0.00657422 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00654391 |
| CTSH | cathepsin H | 0.00651565 |
| XCL1 | chemokine (C motif) ligand 1 | 0.00651216 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00645535 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00644021 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.00641974 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.0063969 |
| PTK2B | protein tyrosine kinase 2 beta | 0.006394 |
| H1-2 | H1.2 linker histone, cluster member | 0.00638796 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.00638637 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00638252 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00636426 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00635078 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00629085 |
| CD46 | CD46 molecule, complement regulatory protein | 0.00623621 |
| KIF5B | kinesin family member 5B | 0.0062213 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.0062059 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00619764 |
| NCDN | neurochondrin | 0.00616912 |
| RND3 | Rho family GTPase 3 | 0.0061571 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00611937 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00611651 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00610306 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00609937 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00604442 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00604406 |
| CLIC4 | chloride intracellular channel 4 | 0.0060343 |
| MX1 | MX dynamin-like GTPase 1 | 0.00601646 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.0060007 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00598799 |
| TNS3 | tensin 3 | 0.00598336 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00595466 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00594615 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.0059373 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00589713 |
| S100A2 | S100 calcium binding protein A2 | 0.00583587 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00583526 |
| RGCC | regulator of cell cycle | 0.00579501 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00576553 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.00565883 |
| KRT6A | keratin 6A, type II | 0.00565346 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00562678 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00560256 |
| PLIN2 | perilipin 2 | 0.00555553 |
| IRF7 | interferon regulatory factor 7 | 0.00554135 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00552849 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00548868 |
| IPO13 | importin 13 | 0.00547904 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.00546678 |
| S100A9 | S100 calcium binding protein A9 | 0.00542933 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.00541883 |
| CHN1 | chimerin 1 | 0.00540924 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 0.00539605 |
| RBM47 | RNA binding motif protein 47 | 0.00539296 |
| PPL | periplakin | 0.00536578 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0053542 |
| TPD52L1 | tumor protein D52-like 1 | 0.00535106 |
| DSP | desmoplakin | 0.00531082 |
| NXN | nucleoredoxin | 0.00530052 |
| YME1L1 | YME1-like 1 ATPase | 0.0052952 |
| TRIB2 | tribbles pseudokinase 2 | 0.00526935 |
| SC5D | sterol-C5-desaturase | 0.00525559 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00524321 |
| USP18 | ubiquitin specific peptidase 18 | 0.00524163 |
| KLHL24 | kelch-like family member 24 | 0.00524064 |
| TBX3 | T-box 3 | 0.00523436 |
| ATP6V1E1 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | 0.00523435 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00522134 |
| IRF9 | interferon regulatory factor 9 | 0.00521784 |
| KLHDC10 | kelch domain containing 10 | 0.00521773 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00519139 |
| HIST1H2AE | histone cluster 1, H2ae | 0.00518803 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00516607 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00513599 |
| FRMD4B | FERM domain containing 4B | 0.0051335 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00512176 |
| FOXF1 | forkhead box F1 | 0.00512097 |
| CD69 | CD69 molecule | 0.00510504 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.00509192 |
| JAG1 | jagged 1 | 0.00507995 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00507796 |
| S100A8 | S100 calcium binding protein A8 | 0.00507056 |
| DUSP14 | dual specificity phosphatase 14 | 0.00505115 |
| DOCK4 | dedicator of cytokinesis 4 | 0.00505046 |
| OLFML2A | olfactomedin-like 2A | 0.00505 |
| ACOT13 | acyl-CoA thioesterase 13 | 0.00504262 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00504096 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00502572 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.00502151 |
| SHTN1 | shootin 1 | 0.00501939 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00501166 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 0.00500503 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.00499074 |
| IL1RN | interleukin 1 receptor antagonist | 0.004936 |
| MEIS2 | Meis homeobox 2 | 0.0049336 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | 0.00492354 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.0049077 |
| TULP4 | tubby like protein 4 | 0.00490526 |
| YAP1 | Yes-associated protein 1 | 0.00490441 |
| CCNG2 | cyclin G2 | 0.00488459 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 | 0.00487826 |
| APOC1 | apolipoprotein C-I | 0.00487228 |
| NVL | nuclear VCP-like | 0.00487106 |
| KLK3 | kallikrein-related peptidase 3 | 0.00487094 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00486691 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00485703 |
| KLK2 | kallikrein-related peptidase 2 | 0.00484816 |
| PLS1 | plastin 1 | 0.00484103 |
| NOTCH1 | notch 1 | 0.00483734 |
| TTN | titin | 0.00483535 |
| EFNB2 | ephrin-B2 | 0.00482801 |
| GLO1 | glyoxalase I | 0.00482626 |
| RIT1 | Ras-like without CAAX 1 | 0.00482291 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00482216 |
| MYO10 | myosin X | 0.00481067 |
| NPY | neuropeptide Y | 0.00480948 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 | 0.00480875 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00478462 |
| IL1B | interleukin 1, beta | 0.00477785 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00477687 |
| NAV2 | neuron navigator 2 | 0.00477496 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00475686 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 | 0.0047555 |
| N4BP1 | NEDD4 binding protein 1 | 0.0047516 |
| CP | ceruloplasmin (ferroxidase) | 0.00475009 |
| AVPI1 | arginine vasopressin-induced 1 | 0.00473957 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00473111 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00472885 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00472877 |
| GPX1 | glutathione peroxidase 1 | 0.00472732 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00472148 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0047146 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.00471239 |
| TLK2 | tousled-like kinase 2 | 0.00470604 |
| RXRA | retinoid X receptor, alpha | 0.0047035 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | 0.00468147 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00467451 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 0.00465686 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00465215 |
| SVIL | supervillin | 0.00464789 |
| LRRC1 | leucine rich repeat containing 1 | 0.00463782 |
| FOXF2 | forkhead box F2 | 0.00463486 |
| COG7 | component of oligomeric golgi complex 7 | 0.00462436 |
| GPR65 | G protein-coupled receptor 65 | 0.00461782 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.00461164 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00460628 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00460488 |
| MINK1 | misshapen-like kinase 1 | 0.0046014 |
| RNF44 | ring finger protein 44 | 0.0045965 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00459164 |
| TXLNA | taxilin alpha | 0.00457227 |
| EFNA1 | ephrin-A1 | 0.0045642 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.00456377 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00455313 |
| SNAI2 | snail family zinc finger 2 | 0.00454532 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.00453887 |
| ARPP21 | cAMP-regulated phosphoprotein, 21kDa | 0.00453675 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00453135 |
| HOXA10 | homeobox A10 | 0.00452563 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00451655 |
| REXO2 | RNA exonuclease 2 | 0.00450712 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0044886 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0044881 |
| TGFB1 | transforming growth factor, beta 1 | 0.00448713 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0044722 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.00446853 |
| KRT5 | keratin 5, type II | 0.00446232 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00445905 |
| IFI44 | interferon-induced protein 44 | 0.00445487 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00444848 |
| CLEC3B | C-type lectin domain family 3, member B | 0.00444695 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00444537 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00444432 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00444033 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0044389 |
| PXDC1 | PX domain containing 1 | 0.0044246 |
| KAT2B | K(lysine) acetyltransferase 2B | 0.00442207 |
| KRT17 | keratin 17, type I | 0.00441937 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0044191 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00441812 |
| CPM | carboxypeptidase M | 0.00441728 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00441669 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00440123 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.00439615 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 | 0.00438804 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HOXC6 | homeobox C6 | -0.0122599 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0113743 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0106845 |
| TFF1 | trefoil factor 1 | -0.0103456 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0102385 |
| EGR2 | early growth response 2 | -0.00986439 |
| MFAP5 | microfibrillar associated protein 5 | -0.00920002 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00904459 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00889095 |
| MAGEA3 | melanoma antigen family A3 | -0.00876066 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00831391 |
| C7 | complement component 7 | -0.0083052 |
| MAGEA12 | melanoma antigen family A12 | -0.00818469 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00816409 |
| XPO7 | exportin 7 | -0.0079688 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.00796254 |
| GAS1 | growth arrest-specific 1 | -0.00794652 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0078896 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00786061 |
| FABP7 | fatty acid binding protein 7, brain | -0.00782694 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00766017 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.0076015 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.0075504 |
| OXTR | oxytocin receptor | -0.00741154 |
| PEG3 | paternally expressed 3 | -0.00727937 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00727297 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00711966 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00696857 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.0068907 |
| ESR1 | estrogen receptor 1 | -0.00683362 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0068266 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00680731 |
| CHGB | chromogranin B | -0.00676944 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -0.00674288 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00672317 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.00652787 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00647195 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -0.00646901 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00646401 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00644209 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00642022 |
| SCG5 | secretogranin V | -0.00641469 |
| CD200 | CD200 molecule | -0.00637889 |
| NELL2 | NEL-like 2 (chicken) | -0.006363 |
| MDFIC | MyoD family inhibitor domain containing | -0.00634598 |
| NLGN4X | neuroligin 4, X-linked | -0.00634101 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.00632215 |
| ALDOA | aldolase A, fructose-bisphosphate | -0.00629257 |
| CDCA4 | cell division cycle associated 4 | -0.00628361 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00624265 |
| CTSZ | cathepsin Z | -0.00622241 |
| GPC3 | glypican 3 | -0.00620355 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00619748 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -0.00617698 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00616068 |
| PTDSS1 | phosphatidylserine synthase 1 | -0.00612568 |
| INSR | insulin receptor | -0.00609131 |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | -0.0060886 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00607776 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00606914 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00605288 |
| TWF2 | twinfilin actin binding protein 2 | -0.00603821 |
| ASF1B | anti-silencing function 1B histone chaperone | -0.00601123 |
| ILK | integrin-linked kinase | -0.00600407 |
| ASRGL1 | asparaginase like 1 | -0.00600195 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00597599 |
| ADRA2A | adrenoceptor alpha 2A | -0.00596849 |
| RUVBL1 | RuvB-like AAA ATPase 1 | -0.00593961 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | -0.00592265 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00591818 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0059038 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00582783 |
| LASP1 | LIM and SH3 protein 1 | -0.00577981 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00575816 |
| CLDN8 | claudin 8 | -0.00574719 |
| CCNA2 | cyclin A2 | -0.00574376 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00573712 |
| FKBP5 | FK506 binding protein 5 | -0.00571933 |
| PODXL | podocalyxin-like | -0.00565676 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00563299 |
| CLTB | clathrin, light chain B | -0.00562957 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00562077 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00560586 |
| E2F2 | E2F transcription factor 2 | -0.00558093 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.00555974 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00555505 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -0.00555124 |
| GOLM1 | golgi membrane protein 1 | -0.00553007 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.0055013 |
| IFRD2 | interferon-related developmental regulator 2 | -0.0054935 |
| IER2 | immediate early response 2 | -0.00547184 |
| GOLGA8A | golgin A8 family, member A | -0.00546643 |
| LOXL1 | lysyl oxidase-like 1 | -0.00546266 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00543792 |
| CIRBP | cold inducible RNA binding protein | -0.00543789 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00542842 |
| MMP3 | matrix metallopeptidase 3 | -0.00540286 |
| BRCA1 | breast cancer 1, early onset | -0.00536961 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -0.00534019 |
| TFF2 | trefoil factor 2 | -0.00533674 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.0053173 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00531725 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -0.00531252 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00531029 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -0.00529002 |
| ACAA2 | acetyl-CoA acyltransferase 2 | -0.00525723 |
| RIMBP2 | RIMS binding protein 2 | -0.00525235 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00525091 |
| ALB | albumin | -0.00523327 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00521288 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00517016 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.00516874 |
| EGR3 | early growth response 3 | -0.00513412 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00513297 |
| KARS1 | lysyl-tRNA synthetase 1 | -0.00511537 |
| DOK5 | docking protein 5 | -0.00509398 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00508869 |
| MAL | mal, T-cell differentiation protein | -0.0050845 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.00507366 |
| PFKL | phosphofructokinase, liver | -0.00506594 |
| COQ8A | coenzyme Q8A | -0.00505572 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.00504405 |
| METTL7A | methyltransferase like 7A | -0.00502334 |
| COL10A1 | collagen, type X, alpha 1 | -0.00498658 |
| GLDC | glycine dehydrogenase (decarboxylating) | -0.00497179 |
| FBLN5 | fibulin 5 | -0.00496373 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | -0.0049533 |
| POSTN | periostin, osteoblast specific factor | -0.00493358 |
| PRMT2 | protein arginine methyltransferase 2 | -0.00491887 |
| MMP1 | matrix metallopeptidase 1 | -0.00489684 |
| MBD2 | methyl-CpG binding domain protein 2 | -0.00487101 |
| MB | myoglobin | -0.00483847 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00483573 |
| RXYLT1 | ribitol xylosyltransferase 1 | -0.0048357 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00483027 |
| DCPS | decapping enzyme, scavenger | -0.0048158 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00479967 |
| FBL | fibrillarin | -0.00478366 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | -0.00477659 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00477632 |
| CCN2 | cellular communication network factor 2 | -0.00477105 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.00476701 |
| THYN1 | thymocyte nuclear protein 1 | -0.00475948 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00475776 |
| B3GNT1 | -0.00475513 | |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00475447 |
| PLIN3 | perilipin 3 | -0.00474907 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00474757 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00473363 |
| COL1A2 | collagen, type I, alpha 2 | -0.0047196 |
| CTSE | cathepsin E | -0.00471633 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0047144 |
| NSG1 | neuron specific gene family member 1 | -0.00469987 |
| ANXA5 | annexin A5 | -0.0046926 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0046849 |
| RCAN1 | regulator of calcineurin 1 | -0.00468283 |
| TYRP1 | tyrosinase-related protein 1 | -0.00468159 |
| NFASC | neurofascin | -0.00467894 |
| HOXB7 | homeobox B7 | -0.00466412 |
| AK4 | adenylate kinase 4 | -0.00466345 |
| LAMA2 | laminin, alpha 2 | -0.00464951 |
| AHCY | adenosylhomocysteinase | -0.00464823 |
| STMN2 | stathmin 2 | -0.00464707 |
| AMPH | amphiphysin | -0.00463539 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.00461978 |
| MAGEA1 | melanoma antigen family A1 | -0.00461428 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | -0.00460669 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.00459723 |
| OLFML3 | olfactomedin-like 3 | -0.00459421 |
| HARS1 | histidyl-tRNA synthetase 1 | -0.0045853 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -0.00458174 |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) | -0.00458013 |
| F2R | coagulation factor II (thrombin) receptor | -0.00457512 |
| ICAM3 | intercellular adhesion molecule 3 | -0.00456536 |
| PNMA1 | paraneoplastic Ma antigen 1 | -0.00455754 |
| IL17RB | interleukin 17 receptor B | -0.00455496 |
| LMNB1 | lamin B1 | -0.00454598 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00452551 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00452459 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00451732 |
| SELL | selectin L | -0.00450971 |
| GSTM5 | glutathione S-transferase mu 5 | -0.00450807 |
| PRKD3 | protein kinase D3 | -0.00450728 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00450296 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | -0.00450191 |
| ARL14 | ADP-ribosylation factor-like 14 | -0.00448006 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00447803 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00447193 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00447048 |
| HOMER1 | homer scaffolding protein 1 | -0.00446578 |
| JAM2 | junctional adhesion molecule 2 | -0.00446091 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | -0.00443388 |
| DNTT | DNA nucleotidylexotransferase | -0.00442576 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00442087 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00441263 |
| AATF | apoptosis antagonizing transcription factor | -0.00440904 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00438975 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | -0.00438897 |
| FPGS | folylpolyglutamate synthase | -0.00438842 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00438076 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00436643 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00436211 |
| DMD | dystrophin | -0.00435373 |
| COLEC11 | collectin sub-family member 11 | -0.00434439 |
| SORBS3 | sorbin and SH3 domain containing 3 | -0.00433102 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00432885 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0043145 |
| EPS8L3 | EPS8-like 3 | -0.00430442 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00430308 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00429597 |
| PLAT | plasminogen activator, tissue | -0.00428993 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00428922 |
| SLC35G2 | solute carrier family 35, member G2 | -0.00428523 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) | -0.00428398 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00427849 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.00425364 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.00425354 |
| MT1H | metallothionein 1H | -0.00423968 |
| TSPYL5 | TSPY-like 5 | -0.00423415 |
| THBS2 | thrombospondin 2 | -0.00422953 |
| PLLP | plasmolipin | -0.00420659 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | -0.00420463 |
| GUCY2C | guanylate cyclase 2C | -0.00419022 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00418131 |
| C21ORF33 | chromosome 21 open reading frame 33 | -0.00417199 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00416705 |
| ITM2A | integral membrane protein 2A | -0.00416621 |
| SMAGP | small cell adhesion glycoprotein | -0.00416273 |
| LEFTY1 | left-right determination factor 1 | -0.00415854 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00415462 |
| CYRIA | CYFIP related Rac1 interactor A | -0.00415374 |
| DALRD3 | DALR anticodon binding domain containing 3 | -0.00415208 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00415172 |
| KLF2 | Kruppel-like factor 2 | -0.00414262 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | -0.00413682 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -0.00413194 |
| RGS10 | regulator of G-protein signaling 10 | -0.00412443 |
| RPL36AL | ribosomal protein L36a-like | -0.00412436 |
| RAB15 | RAB15, member RAS oncogene family | -0.00410321 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00409264 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00408235 |
| AFP | alpha-fetoprotein | -0.00408029 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00407618 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | -0.00407418 |
| IRX5 | iroquois homeobox 5 | -0.00407113 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -0.00406992 |
| RASA4 | RAS p21 protein activator 4 | -0.00406287 |
| TLCD3A | TLC domain containing 3A | -0.00405868 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.00405793 |
