| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | CD8a molecule|The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] (NCBI Entrez Gene Database, 925) |
| External Link | https://ncbi.nlm.nih.gov/gene/925 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the CD8A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0165588 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0137551 |
| THBS2 | thrombospondin 2 | 0.0135665 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0119339 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.0118871 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0118052 |
| MX1 | MX dynamin-like GTPase 1 | 0.0116801 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0116617 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.011533 |
| SFRP1 | secreted frizzled-related protein 1 | 0.011476 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0111306 |
| RET | ret proto-oncogene | 0.0109527 |
| XIC | X chromosome inactivation center | 0.0106999 |
| PEG3 | paternally expressed 3 | 0.0105108 |
| MATN2 | matrilin 2 | 0.010429 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0103407 |
| MME | membrane metallo-endopeptidase | 0.0103306 |
| CA2 | carbonic anhydrase II | 0.0101524 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00981014 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00974154 |
| BAX | BCL2-associated X protein | 0.00955646 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00952432 |
| KLF6 | Kruppel-like factor 6 | 0.00951863 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00949374 |
| PLLP | plasmolipin | 0.00939328 |
| CD200 | CD200 molecule | 0.00926025 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00924188 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00922642 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00914325 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00913614 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00909832 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00886866 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00884759 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00880772 |
| CLIC5 | chloride intracellular channel 5 | 0.00875818 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00870768 |
| OGN | osteoglycin | 0.00870324 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00866848 |
| ALB | albumin | 0.00854716 |
| CDC20 | cell division cycle 20 | 0.0084755 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00845555 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00842294 |
| TFF1 | trefoil factor 1 | 0.00838441 |
| FBLN5 | fibulin 5 | 0.00836604 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00834367 |
| LEFTY1 | left-right determination factor 1 | 0.00831043 |
| FILIP1L | filamin A interacting protein 1-like | 0.0082849 |
| ZNF160 | zinc finger protein 160 | 0.00827888 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.0082772 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00826993 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00825397 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00818022 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00815316 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.0080716 |
| HOXC6 | homeobox C6 | 0.00804951 |
| TNNC1 | troponin C type 1 (slow) | 0.00803853 |
| HSPB8 | heat shock 22kDa protein 8 | 0.0079845 |
| ZNF721 | zinc finger protein 721 | 0.00795209 |
| MEG3 | maternally expressed 3 (non-protein coding) | 0.00793481 |
| GAS1 | growth arrest-specific 1 | 0.00782716 |
| BMP7 | bone morphogenetic protein 7 | 0.00780754 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00774632 |
| THBS1 | thrombospondin 1 | 0.00773082 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.00772291 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00770365 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00769981 |
| ANXA6 | annexin A6 | 0.00768694 |
| ANK2 | ankyrin 2, neuronal | 0.00767801 |
| COL10A1 | collagen, type X, alpha 1 | 0.00765704 |
| PXDN | peroxidasin | 0.00756394 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00754456 |
| KRT23 | keratin 23, type I | 0.00749865 |
| FHOD3 | formin homology 2 domain containing 3 | 0.00745696 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00741634 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00731323 |
| OPHN1 | oligophrenin 1 | 0.00731183 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00724165 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00722836 |
| PNMA8A | PNMA family member 8A | 0.0071653 |
| NPEPL1 | aminopeptidase-like 1 | 0.00714594 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00714368 |
| DCN | decorin | 0.00712208 |
| C7 | complement component 7 | 0.00711707 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00708619 |
| BEX1 | brain expressed, X-linked 1 | 0.00707194 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00706182 |
| RGS5 | regulator of G-protein signaling 5 | 0.00705528 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00703072 |
| FBXW12 | F-box and WD repeat domain containing 12 | 0.00702913 |
| COLEC11 | collectin sub-family member 11 | 0.00701936 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00701823 |
| MGLL | monoglyceride lipase | 0.00700561 |
| RTN2 | reticulon 2 | 0.00699555 |
| TSPAN8 | tetraspanin 8 | 0.00698913 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit | 0.00694606 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | 0.00691257 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00686945 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00686943 |
| THBS4 | thrombospondin 4 | 0.00685236 |
| TAC1 | tachykinin, precursor 1 | 0.00681598 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00681364 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00679686 |
| CLTB | clathrin, light chain B | 0.00679298 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.0067834 |
| TMEM255A | transmembrane protein 255A | 0.00677231 |
| ESR1 | estrogen receptor 1 | 0.00676872 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00675142 |
| CCN2 | cellular communication network factor 2 | 0.00674058 |
| GPR137B | G protein-coupled receptor 137B | 0.00673163 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00671607 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00670585 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00670261 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) | 0.00670057 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00669097 |
| ZNF611 | zinc finger protein 611 | 0.00667298 |
| AK1 | adenylate kinase 1 | 0.00666975 |
| COG7 | component of oligomeric golgi complex 7 | 0.00666968 |
| NEBL | nebulette | 0.00665353 |
| RXYLT1 | ribitol xylosyltransferase 1 | 0.00665318 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00664291 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.0066378 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00663091 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00662961 |
| COX5A | cytochrome c oxidase subunit Va | 0.00658712 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00657609 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00652832 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00650051 |
| GPC3 | glypican 3 | 0.00649185 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00647827 |
| INSR | insulin receptor | 0.00647703 |
| HELLS | helicase, lymphoid-specific | 0.00647583 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00645798 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00642808 |
| OXTR | oxytocin receptor | 0.00642185 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00642156 |
| CALCA | calcitonin-related polypeptide alpha | 0.00637913 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.00637679 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.00630951 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | 0.00630163 |
| RETREG1 | reticulophagy regulator 1 | 0.00629683 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00629418 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00629415 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0062795 |
| RRAD | Ras-related associated with diabetes | 0.00627207 |
| TSPYL5 | TSPY-like 5 | 0.00627093 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00626756 |
| FBN1 | fibrillin 1 | 0.00626508 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.00625735 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.00625164 |
| BICC1 | BicC family RNA binding protein 1 | 0.00624715 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00623918 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.00622971 |
| AURKB | aurora kinase B | 0.00622959 |
| FSTL1 | follistatin-like 1 | 0.00622952 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00622576 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00620724 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00620459 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0061973 |
| PPT2 | palmitoyl-protein thioesterase 2 | 0.00619125 |
| MPO | myeloperoxidase | 0.00618392 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00617761 |
| TMEM63A | transmembrane protein 63A | 0.00614084 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00613933 |
| TFRC | transferrin receptor | 0.00611967 |
| ACKR3 | atypical chemokine receptor 3 | 0.00611618 |
| OLFML3 | olfactomedin-like 3 | 0.00611363 |
| PEG10 | paternally expressed 10 | 0.00610415 |
| NDE1 | nudE neurodevelopment protein 1 | 0.00608788 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00608754 |
| SGCE | sarcoglycan, epsilon | 0.00607369 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.00605886 |
| CDV3 | CDV3 homolog (mouse) | 0.00605818 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00605758 |
| GAL | galanin/GMAP prepropeptide | 0.00605715 |
| FCGBP | Fc fragment of IgG binding protein | 0.00604435 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00602889 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.00602493 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.0060164 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00601258 |
| SNX7 | sorting nexin 7 | 0.0060096 |
| PRR11 | proline rich 11 | 0.00600894 |
| FGA | fibrinogen alpha chain | 0.00600285 |
| STMN2 | stathmin 2 | 0.00599579 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | 0.00599403 |
| EMP2 | epithelial membrane protein 2 | 0.00598827 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0059803 |
| TTN | titin | 0.00597046 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 0.00596712 |
| NEFM | neurofilament, medium polypeptide | 0.0059399 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00593019 |
| AEBP1 | AE binding protein 1 | 0.00592279 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00591676 |
| SIX1 | SIX homeobox 1 | 0.00591359 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00589949 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00589231 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00588713 |
| FA2H | fatty acid 2-hydroxylase | 0.00588585 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.00587307 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00587059 |
| RYR1 | ryanodine receptor 1 (skeletal) | 0.00585054 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00584379 |
| ECM1 | extracellular matrix protein 1 | 0.00584132 |
| PRKX | protein kinase, X-linked | 0.00584107 |
| L1CAM | L1 cell adhesion molecule | 0.00582298 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00582019 |
| TFDP1 | transcription factor Dp-1 | 0.00581531 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00579608 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 0.00579113 |
| MFAP5 | microfibrillar associated protein 5 | 0.00577785 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 0.0057656 |
| MSLN | mesothelin | 0.00575811 |
| CLDN3 | claudin 3 | 0.00575522 |
| MXRA5 | matrix-remodelling associated 5 | 0.00573776 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | 0.0057332 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00572381 |
| SSPN | sarcospan | 0.0057156 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00569506 |
| ZNF44 | zinc finger protein 44 | 0.00568654 |
| KLHL41 | kelch-like family member 41 | 0.00568391 |
| TSPAN3 | tetraspanin 3 | 0.0056829 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00568284 |
| ASS1 | argininosuccinate synthase 1 | 0.00567877 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00567742 |
| ZFHX4 | zinc finger homeobox 4 | 0.0056723 |
| DEFB1 | defensin, beta 1 | 0.00564157 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00563856 |
| ASPN | asporin | 0.00563568 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00563566 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00563001 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00562609 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00560702 |
| RRAGD | Ras-related GTP binding D | 0.00558631 |
| ATP10B | ATPase, class V, type 10B | 0.00557475 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00557315 |
| RUFY3 | RUN and FYVE domain containing 3 | 0.00557267 |
| CHIT1 | chitinase 1 (chitotriosidase) | 0.00555446 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 | 0.00554077 |
| MAP9 | microtubule-associated protein 9 | 0.00553751 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.00553053 |
| ALDOA | aldolase A, fructose-bisphosphate | 0.00551334 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.00550658 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 | 0.00549662 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00549188 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00548317 |
| BNC2 | basonuclin 2 | 0.0054793 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | 0.00546215 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.0054612 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.00544495 |
| INAVA | innate immunity activator | 0.00544359 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.00541025 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.014156 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.0129301 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0127518 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0114724 |
| KRT17 | keratin 17, type I | -0.0114247 |
| LTF | lactotransferrin | -0.0107906 |
| C1QB | complement component 1, q subcomponent, B chain | -0.0107824 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0107515 |
| CSTA | cystatin A (stefin A) | -0.0103182 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.0101255 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00996988 |
| S100A8 | S100 calcium binding protein A8 | -0.00995989 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00993687 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00993549 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.0098225 |
| CD163 | CD163 molecule | -0.0097804 |
| RPS5 | ribosomal protein S5 | -0.0096195 |
| CD14 | CD14 molecule | -0.00931257 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00929958 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.00927854 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00926772 |
| SFN | stratifin | -0.00923151 |
| TRIB2 | tribbles pseudokinase 2 | -0.0091026 |
| RHOB | ras homolog family member B | -0.00906901 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00894235 |
| REG1A | regenerating islet-derived 1 alpha | -0.00874253 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00871085 |
| RIN2 | Ras and Rab interactor 2 | -0.00868297 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00853652 |
| PDGFC | platelet derived growth factor C | -0.00842198 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.00832541 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00818904 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.0081626 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00815592 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00812196 |
| TCTA | T-cell leukemia translocation altered | -0.00808467 |
| CST3 | cystatin C | -0.00801356 |
| COPS7A | COP9 signalosome subunit 7A | -0.00798449 |
| KRT6A | keratin 6A, type II | -0.00797896 |
| IQCG | IQ motif containing G | -0.00794876 |
| GFAP | glial fibrillary acidic protein | -0.00794073 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0079363 |
| CD320 | CD320 molecule | -0.00785725 |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase | -0.0076991 |
| EXOSC4 | exosome component 4 | -0.00769162 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.0076794 |
| STAB1 | stabilin 1 | -0.00766649 |
| REG3A | regenerating islet-derived 3 alpha | -0.00764735 |
| S100A9 | S100 calcium binding protein A9 | -0.00763173 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00759583 |
| CHN2 | chimerin 2 | -0.00757871 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.00754993 |
| MCOLN1 | mucolipin 1 | -0.00754963 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00745625 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00743689 |
| PRF1 | perforin 1 (pore forming protein) | -0.00743615 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.0073776 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00735571 |
| COMT | catechol-O-methyltransferase | -0.00733337 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00732672 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00729259 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00727957 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00727375 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00725263 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0072044 |
| CCR1 | chemokine (C-C motif) receptor 1 | -0.00706445 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.00705633 |
| S100A2 | S100 calcium binding protein A2 | -0.00701919 |
| RGS2 | regulator of G-protein signaling 2 | -0.00700608 |
| DGS2 | DiGeorge syndrome/velocardiofacial syndrome complex 2 | -0.00695911 |
| CHI3L2 | chitinase 3-like 2 | -0.00694384 |
| AMD1 | adenosylmethionine decarboxylase 1 | -0.00689676 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00688696 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00688269 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00680911 |
| ZNF266 | zinc finger protein 266 | -0.00679115 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.006778 |
| HIC2 | hypermethylated in cancer 2 | -0.00677016 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00676993 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00673698 |
| MRTFB | myocardin related transcription factor B | -0.00673676 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00672731 |
| CHN1 | chimerin 1 | -0.00665538 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00664819 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00663285 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00662801 |
| H1-2 | H1.2 linker histone, cluster member | -0.0066082 |
| NDP | Norrie disease (pseudoglioma) | -0.00659877 |
| TSPAN13 | tetraspanin 13 | -0.00658986 |
| TMEM106B | transmembrane protein 106B | -0.00658685 |
| MAGEB2 | melanoma antigen family B2 | -0.00657556 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | -0.00657168 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | -0.00648575 |
| NXT2 | nuclear transport factor 2-like export factor 2 | -0.00646862 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00645065 |
| STK38L | serine/threonine kinase 38 like | -0.00642853 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.00641257 |
| PDLIM4 | PDZ and LIM domain 4 | -0.00638311 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00637964 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | -0.00637953 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | -0.006372 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00637115 |
| EMP3 | epithelial membrane protein 3 | -0.00636164 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00635173 |
| GLUL | glutamate-ammonia ligase | -0.00632207 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | -0.00631666 |
| TGFB1 | transforming growth factor, beta 1 | -0.00631338 |
| PRAME | preferentially expressed antigen in melanoma | -0.00630799 |
| CLU | clusterin | -0.00630319 |
| KYNU | kynureninase | -0.00630018 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00624166 |
| SNX10 | sorting nexin 10 | -0.00623972 |
| CEP70 | centrosomal protein 70kDa | -0.00619051 |
| TSPAN7 | tetraspanin 7 | -0.00615473 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -0.00615422 |
| AGR2 | anterior gradient 2 | -0.00615354 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00615146 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0061488 |
| QDPR | quinoid dihydropteridine reductase | -0.00611303 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | -0.00610164 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00607834 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -0.00607699 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | -0.00607693 |
| HIST1H2AE | histone cluster 1, H2ae | -0.00605813 |
| MAGEA3 | melanoma antigen family A3 | -0.00604626 |
| NOTCH2 | notch 2 | -0.00604501 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00603658 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00602801 |
| FGF13 | fibroblast growth factor 13 | -0.00602095 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | -0.00597959 |
| MGAM | maltase-glucoamylase | -0.00597485 |
| CCL13 | chemokine (C-C motif) ligand 13 | -0.00596949 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.00596847 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00596431 |
| PKP1 | plakophilin 1 | -0.00595007 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00594658 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00594594 |
| RXRA | retinoid X receptor, alpha | -0.00592988 |
| GLUD1 | glutamate dehydrogenase 1 | -0.00592823 |
| ANKRD17 | ankyrin repeat domain 17 | -0.00590801 |
| STX6 | syntaxin 6 | -0.00590023 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00587915 |
| PTRH2 | peptidyl-tRNA hydrolase 2 | -0.00587334 |
| PLTP | phospholipid transfer protein | -0.00586333 |
| TMEM126B | transmembrane protein 126B | -0.00585618 |
| SAR1B | secretion associated, Ras related GTPase 1B | -0.00583238 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.0058314 |
| FBXO7 | F-box protein 7 | -0.0058293 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.00581662 |
| NCKAP1 | NCK-associated protein 1 | -0.00581308 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | -0.00581216 |
| PMP22 | peripheral myelin protein 22 | -0.00578929 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00578799 |
| PLBD1 | phospholipase B domain containing 1 | -0.00578076 |
| LY86 | lymphocyte antigen 86 | -0.00576097 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | -0.00575616 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00575589 |
| TMEM135 | transmembrane protein 135 | -0.0057442 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00573554 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) | -0.00572868 |
| ABHD6 | abhydrolase domain containing 6 | -0.00571712 |
| SGMS1 | sphingomyelin synthase 1 | -0.00569998 |
| KCTD5 | potassium channel tetramerization domain containing 5 | -0.00568688 |
| PDLIM1 | PDZ and LIM domain 1 | -0.00567188 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00567106 |
| EFHD2 | EF-hand domain family, member D2 | -0.00567038 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0056537 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00564277 |
| RAB6A | RAB6A, member RAS oncogene family | -0.00563388 |
| ODC1 | ornithine decarboxylase 1 | -0.0056233 |
| PTK2 | protein tyrosine kinase 2 | -0.00562306 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.00562186 |
| KRT14 | keratin 14, type I | -0.00561298 |
| TRIM37 | tripartite motif containing 37 | -0.00560252 |
| INSIG2 | insulin induced gene 2 | -0.0056003 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00558731 |
| MED21 | mediator complex subunit 21 | -0.00558117 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.0055539 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.00553584 |
| WDR44 | WD repeat domain 44 | -0.00553552 |
| CD86 | CD86 molecule | -0.00553046 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) | -0.00550735 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -0.0054994 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00548611 |
| NIT1 | nitrilase 1 | -0.00548444 |
| HDAC9 | histone deacetylase 9 | -0.0054736 |
| IL2RB | interleukin 2 receptor, beta | -0.00546791 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00545615 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.0054542 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 | -0.00544501 |
| SORD | sorbitol dehydrogenase | -0.00542898 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.00542827 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00542501 |
| DMXL2 | Dmx-like 2 | -0.00542376 |
| TPD52L1 | tumor protein D52-like 1 | -0.00541642 |
| CRYL1 | crystallin, lambda 1 | -0.00540648 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -0.00540556 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0053957 |
| KRT5 | keratin 5, type II | -0.00538718 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | -0.00538141 |
| TLR4 | toll-like receptor 4 | -0.00537562 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.00537006 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00536571 |
| CDCP1 | CUB domain containing protein 1 | -0.00533221 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | -0.00532827 |
| ACACA | acetyl-CoA carboxylase alpha | -0.00532238 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00530794 |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 | -0.00529034 |
| KIF1B | kinesin family member 1B | -0.00528588 |
| FPR1 | formyl peptide receptor 1 | -0.00528515 |
| CCN3 | cellular communication network factor 3 | -0.00528007 |
| CLCN3 | chloride channel, voltage-sensitive 3 | -0.00527908 |
| CHPT1 | choline phosphotransferase 1 | -0.00527797 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | -0.00527797 |
| THAP12 | THAP domain containing 12 | -0.00527641 |
| EMP1 | epithelial membrane protein 1 | -0.00527158 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | -0.0052665 |
| FAM172A | family with sequence similarity 172, member A | -0.00524845 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.00524399 |
| RIT1 | Ras-like without CAAX 1 | -0.00524275 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00524151 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00523623 |
| SCARA3 | scavenger receptor class A, member 3 | -0.00521336 |
| SCLY | selenocysteine lyase | -0.0052131 |
| TBC1D31 | TBC1 domain family, member 31 | -0.00520804 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00520364 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.00518868 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | -0.00518171 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00518109 |
| CASC3 | cancer susceptibility candidate 3 | -0.00516954 |
| ACO1 | aconitase 1, soluble | -0.0051628 |
| CD9 | CD9 molecule | -0.00516148 |
| SHROOM2 | shroom family member 2 | -0.00515548 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00514138 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.00513044 |
| PXN | paxillin | -0.00512457 |
| SLC38A6 | solute carrier family 38, member 6 | -0.00511395 |
| ACP3 | acid phosphatase 3 | -0.00511164 |
| HPSE | heparanase | -0.00509245 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00509005 |
| TLN1 | talin 1 | -0.0050739 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00506825 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | -0.00506418 |
| KRT6B | keratin 6B, type II | -0.00505366 |
| LRRC59 | leucine rich repeat containing 59 | -0.00504498 |
| TLK2 | tousled-like kinase 2 | -0.00504486 |
| CD209 | CD209 molecule | -0.0050429 |
