CD8A Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description CD8a molecule|The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] (NCBI Entrez Gene Database, 925)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CD8A
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Genes

127 co-expressed genes for CD8A from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADAM20 ADAM metallopeptidase domain 20
ADAMTSL3 ADAMTS-like 3
AOC4P amine oxidase, copper containing 4, pseudogene
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
AQP7 aquaporin 7
ARL3 ADP-ribosylation factor-like 3
ASB4 ankyrin repeat and SOCS box containing 4
ATXN3 ataxin 3
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMP10 bone morphogenetic protein 10
CADM4 cell adhesion molecule 4
CALN1 calneuron 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCL16 chemokine (C-C motif) ligand 16
CD8A CD8a molecule
CDC73 cell division cycle 73
COL14A1 collagen, type XIV, alpha 1
COL19A1 collagen, type XIX, alpha 1
COL8A1 collagen, type VIII, alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CXCL5 chemokine (C-X-C motif) ligand 5
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DBT dihydrolipoamide branched chain transacylase E2
DMD dystrophin
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EPHB2 EPH receptor B2
ERCC4 excision repair cross-complementation group 4
EXOC4 exocyst complex component 4
EXOC6B exocyst complex component 6B
F2RL3 coagulation factor II (thrombin) receptor-like 3
FAM153B family with sequence similarity 153, member B
FAS Fas cell surface death receptor
FBXL4 F-box and leucine-rich repeat protein 4
FGF18 fibroblast growth factor 18
FOSL1 FOS-like antigen 1
FSHR follicle stimulating hormone receptor
FZD5 frizzled class receptor 5
GCA grancalcin, EF-hand calcium binding protein
GJB5 gap junction protein, beta 5, 31.1kDa
GLRA3 glycine receptor, alpha 3
GPR171 G protein-coupled receptor 171
GPR18 G protein-coupled receptor 18
GPR19 G protein-coupled receptor 19
GUCY2F guanylate cyclase 2F, retinal
HCG8 HLA complex group 8
HCRTR2 hypocretin (orexin) receptor 2
HNF1A HNF1 homeobox A
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNA10 interferon, alpha 10
IGH immunoglobulin heavy locus
IGKV7-3 immunoglobulin kappa variable 7-3 (pseudogene)
IL11RA interleukin 11 receptor, alpha
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
IVL involucrin
JRKL JRK-like
KDR kinase insert domain receptor
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KNG1 kininogen 1
KRT2 keratin 2, type II
KRT34 keratin 34, type I
LECT2 leukocyte cell-derived chemotaxin 2
LGI1 leucine-rich, glioma inactivated 1
LOR loricrin
LPPR4 lipid phosphate phosphatase-related protein type 4
MAGEA8 melanoma antigen family A8
MAGEA9 melanoma antigen family A9
MAP2 microtubule-associated protein 2
MC5R melanocortin 5 receptor
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MYT1 myelin transcription factor 1
NPFF neuropeptide FF-amide peptide precursor
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRXN1 neurexin 1
NTNG2 netrin G2
OCM oncomodulin
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PCDHGB7 protocadherin gamma subfamily B, 7
PDCD1 programmed cell death 1
PDE4D phosphodiesterase 4D, cAMP-specific
PGM3 phosphoglucomutase 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHOX2B paired-like homeobox 2b
PLA2R1 phospholipase A2 receptor 1, 180kDa
POU6F1 POU class 6 homeobox 1
PSG1 pregnancy specific beta-1-glycoprotein 1
PTPRB protein tyrosine phosphatase, receptor type, B
PVR poliovirus receptor
R3HCC1L R3H domain and coiled-coil containing 1-like
RAD51D RAD51 paralog D
RORB RAR-related orphan receptor B
RREB1 ras responsive element binding protein 1
RUNX2 runt-related transcription factor 2
RXRG retinoid X receptor, gamma
S100A5 S100 calcium binding protein A5
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SGPL1 sphingosine-1-phosphate lyase 1
SIM2 single-minded family bHLH transcription factor 2
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SPA17 sperm autoantigenic protein 17
STAC SH3 and cysteine rich domain
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBX19 T-box 19
TENM4 teneurin transmembrane protein 4
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TMEM26 transmembrane protein 26
TSSK2 testis-specific serine kinase 2
VSTM4 V-set and transmembrane domain containing 4
ZBTB40 zinc finger and BTB domain containing 40
ZNF141 zinc finger protein 141
ZNF157 zinc finger protein 157
ZSCAN26 zinc finger and SCAN domain containing 26