CD97 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description adhesion G protein-coupled receptor E5|This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011] (NCBI Entrez Gene Database, 976)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CD97
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Genes

38 co-expressed genes for CD97 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
ADCY7 adenylate cyclase 7
ADGRE5 adhesion G protein-coupled receptor E5
AOAH acyloxyacyl hydrolase (neutrophil)
APOBR apolipoprotein B receptor
BIN2 bridging integrator 2
CD244 CD244 molecule, natural killer cell receptor 2B4
CD300A CD300a molecule
CLEC2B C-type lectin domain family 2, member B
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYTIP cytohesin 1 interacting protein
DOK2 docking protein 2, 56kDa
EFHD2 EF-hand domain family, member D2
ELF4 E74-like factor 4 (ets domain transcription factor)
GIMAP6 GTPase, IMAP family member 6
GPR65 G protein-coupled receptor 65
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL10RA interleukin 10 receptor, alpha
IQGAP1 IQ motif containing GTPase activating protein 1
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK1 Janus kinase 1
LITAF lipopolysaccharide-induced TNF factor
MYO1F myosin IF
OSTF1 osteoclast stimulating factor 1
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPRC protein tyrosine phosphatase, receptor type, C
RAP1B RAP1B, member of RAS oncogene family
RIN3 Ras and Rab interactor 3
SELPLG selectin P ligand
STK10 serine/threonine kinase 10
STK38 serine/threonine kinase 38
ZCCHC6 zinc finger, CCHC domain containing 6